Digital Commons Network^™

Delineation Of Precursors In Murine Spleen That Develop In Contact With Splenic Endothelium To Give Novel Dendritic-Like Cells., Jonathan Tan, Pravin Periasamy, Helen O'Neill

Jonathan Tan

Hematopoietic cell lineages are best described in terms of distinct progenitors with limited differentiative capacity. To distinguish cell lineages, it is necessary to define progenitors and induce their differentiation in vitro. We previously reported in vitro development of immature dendritic-like cells (DCs) in long-term cultures (LTCs) of murine spleen, and in cocultures of spleen or bone marrow (BM) over splenic endothelial cell lines derived from LTCs. Cells produced are phenotypically distinct CD11b(hi)CD11c(lo)CD8(-)MHC-II(-) cells, tentatively named L-DCs. Here we delineate L-DC progenitors as different from known DC progenitors in BM and DC precursors in spleen. The progenitor is contained within the …

Haematopoietic Stem Cells In Spleen Have Distinct Differentiative Potential For Antigen Presenting Cells., Jonathan Tan, Helen O'Neill

Jonathan Tan

Dendritic cells (DC) are known to develop from macrophage dendritic progenitors (MDP) in bone marrow (BM), which give rise to conventional (c)DC and monocytes, both dominant antigen presenting cell (APC) subsets in spleen. This laboratory has however defined a distinct dendritic-like cell subset in spleen (L-DC), which can also be derived in long-term cultures of spleen. In line with the restricted in vitro development of only L-DC in these stromal cultures, we questioned whether self-renewing HSC or progenitors exist in spleen with restricted differentiative capacity for only L-DC. Neonatal spleen and BM were compared for their ability to reconstitute mice …

Linking Climate, Human Rights, And Development, Naomi Roht-Arriaza, Lyuba Zarsky

Naomi Roht-Arriaza

Monterey Institute Professor Lyuba Zarsky and Hastings Professor Naomi Roht-Arriaza speak about an investment-led approach to climate resilient development paths.

Simultaneous Determination Of Pramoxine Hcl And Benzalkonium Chloride In Wound Care Solutions By Hplc, Panagiotis Tavlarakis, Jonine Greyling, Nicholas Snow

Nicholas A Snow

No abstract provided.

Pisa In Brief : Highlights From The Full Australian Report : Challenges For Australian Education : Results From Pisa 2009 : The Pisa 2009 Assessment Of Students' Reading, Mathematical And Scientific Literacy., Sue Thomson, Lisa De Bortoli, Marina Nicholas, Kylie Hillman, Sarah Buckley

Kylie Hillman

No abstract provided.

Complementary Spectroscopic Assays For Investigating Protein−Ligand Binding Activity: A Project For The Advanced Chemistry Laboratory, David Mascotti, Mark Waner

Mark J. Waner

A protein−ligand binding, guided-inquiry laboratory project with potential application across the advanced undergraduate curriculum is described. At the heart of the project are fluorescence and spectrophotometric assays utilizing biotin-4-fluorescein and streptavidin. The use of the same stock solutions for an assay that may be examined by two distinct spectroscopic techniques offers an opportunity to discuss not only protein−ligand binding but also to compare instrumental techniques and to discuss the underlying physical principles that are the origins of the assays. In addition to critically evaluating analytical techniques, students are pushed to develop quantitative pipetting, estimation, and experimental-design skills to collect and …

Self-Assessed Emergency Readiness And Training Needs Of Nurses In Rural Texas, Holly Jacobson, Francisco Soto Mas, Chiehwen Hsu

Francisco Soto Mas

Nurses are potential first responders in the case of an emergency, and should play a key role in bioterrorism preparedness and response. The role of nurses becomes more critical in rural areas where local health departments are absent and health professionals are scarce. Given that nurses’ capacity to act will be vital to an emergency response in a rural community, it is imperative to determine their current level of bioterrorism training. The purpose of this study was to assess the level of bioterrorism-related preparedness and training needs of the nursing workforce in Regions 2 and 3 of the Texas Department …

Depoliticizing Pregnancy And The Post-Nuclear Family In Juno, Knocked Up, And Waitress, Kristen Hoerl, Casey Kelly

Kristen Hoerl

Retention In Care Among Hiv-Infected Patients In Resource-Limited Settings: Emerging Insights And New Directions, Elvin Geng, Denis Nash, Andrew Kambugu, Yao Zhang, Paula Braitstein, Katerina Christopoulos, Winnie Muyindike, Mwebesa Bwana, Constantin Yiannoutsos, Maya Petersen, Jeff Martin

Elvin H Geng

In resource-limited settings—where a massive scale up of HIV services has occurred in the last 5 years—both understanding the extent of and improving retention in care presents special challenges. First, retention in care within the decentralizing network of services is likely higher than existing estimates that account only for retention in clinic, and therefore antiretroviral therapy services may be more effective than currently believed. Second, both magnitude and determinants of patient retention vary substantially and therefore encouraging the conduct of locally relevant epidemiology is needed to inform programmatic decisions. Third, socio-structural factors such as program characteristics, transportation, poverty, work/child care …

Development Of Temperature Regulation In Nestling Tree Swallows, Richard Marsh

Richard Marsh

No abstract provided.

Adaptations Of The Gray Catbird Dumetella Carolinensis To Long Distance Migration: Energy Stores And Substrate Concentrations In Plasma, Richard Marsh

Richard Marsh

The major body components (water, lean dry, and fat) were measured in the carcasses of Gray Catbirds from which the flight muscles had been removed. Birds were collected from May through October near Ann Arbor, Michigan and during September and October near Gainesville, Florida. Additionally, the glycogen content of muscle and liver and the concentrations of glucose and triglycerides in plasma were determined in catbirds sampled during fall migration in Florida. Catbirds attained maximum body masses of ∼50 g in Florida, largely due to the addition of fat. Relatively lean birds (∼3-4% body fat) in spring through fall weighed approximately …

Seasonal And Geographic Variation Of Cold Resistance In House Finches Carpodacus Mexicanus, William Dawson, Richard Marsh, William Buttemer, Cynthia Carey

Richard Marsh

The house finch (Carpodacus mexicanus) is resident in tropical and subtropical regions as well as in localities having relatively severe winters. The extent of its winter acclimatization was assessed in freshly captured individuals of this species from southern California and Colorado. In severe cold stress tests involving exposure to Tₐ < −60 C, the former did not remain homeothermic any longer in winter than in late spring, whereas the Colorado birds did (8.8 vs. 97.5 min; P < .001). The capacity for winter acclimatization evident in these Colorado individuals was correlated with modest winter fattening, a response lacking in those from southern …

Platte River: Water For People And Wildlife, William Graf

William L. Graf

No abstract provided.

Inside The Beltway: Geography At The National Research Council, William Graf

William L. Graf

Professor Graf provides ample reason why all geographers need to be cognizant of the work by the National Research Councils (NRC) two bodies focussed on mapping issues.“The importance of the two geography committees at NRC is that they give American geographers a voice in issues of national and international importance, and they put geographers on a similar footing with physicists, chemists, medical specialists, biologists, and other scientists.” Read about what has been done and how to get involved…only at Directions Magazine.

Testimony In Support Of The Congaree National Park Act Of 2003, William Graf

William L. Graf

No abstract provided.

The Changing Role Of Dams In Water Resources Management, William Graf

William L. Graf

No abstract provided.

Plutonium In River Sediments Of The Northern Rio Grande: The Los Alamos Contribution In Context, William Graf

William L. Graf

No abstract provided.

Dam Removal Research, William Graf

William L. Graf

No abstract provided.

The Geomorphology Of The Glacial Valley Cross Section, William Graf

William L. Graf

Several alpine valley systems in the southeastern Beartooth Mountains, Montana and Wyoming, have been examined using techniques similar to methods of stream system analysis. The general equation y = a x**b is the most adequate mathematical model for the cross valley profile; b values range between 1.5 and 2.0, indicating a parabolic form. As intensity of erosion increases in the glacial valley system, the b value also increases, indicating relatively deeper and narrower valley cross sections. The law of stream numbers, the law of stream lengths, and the bifurcation ratio, derived from fluvial geomorphology, are also applicable in glacial geomorphology.

The Distribution Of Glaciers In The American Rocky Mountains, William Graf

William L. Graf

No abstract provided.

Channel Instability In A Braided Sand Bed River, William Graf

William L. Graf

The Gila River of central Arizona is representative of braided, sand bed rivers in alluvial valleys that have inherent unstable behavior and destructive channel migration. The 112-year record of channel conditions along a portion of the Gila River provides data for the construction of locational probability maps for main flow channels. Zones of stability and hazardous instability alternate with each other at 3.2 km (2 mi) intervals. During the past century the overall sinuosity of the main flow channel has remained close to 1.18, despite numerous changes in actual location. Spatial and temporal variation of sinuosity have occurred in subreaches …

Geography And The Restoration Of Rivers For Wildlife, William Graf

William L. Graf

Since its establishment in 1973, the Endangered Species Act (ESA) has assumed a gradually increasing importance in environmental management in the United States.The effect of the Act is especially significant in matters related to water management in rivers.This brief article addresses the following questions: why has ESA become so important in water and river matters? And what is the role of geographic technology and knowledge in addressing these issues? The article concludes with two case examples where restoration is underway in attempts to reverse the loss of wildlife.

Apotential Lessons For The Cesi Program From The Grand Canyon, William Graf

William L. Graf

No abstract provided.

Dam Nation: A Geographic Census Of American Dams And Their Large-Scale Hydrologic Impacts, William Graf

William L. Graf

Newly available data indicate that darns fragment the fluvial system of the continental United States and that their impact on river discharge is several times greater than impacts deemed likely as a result of global climate change. The 75,000 dams in the continental United States are capable of storing a volume of water almost equaling one year's mean runoff, but there is considerable geographic variation in potential surface water impacts. In some western mountain and plains regions, darns can store more than 3 year's runoff, while in the Northeast and Northwest, storage is as little as 25% of the annual …

The Effect Of Dam Closure On Downstream Rapids, William Graf

William L. Graf

The force of flowing water and the resistance of the largest boulder provide a means of evaluation of the stability of rapids in canyon rivers. Field measurements and calculations show that the closure of Flaming Gorge Dam, Utah, has had a significant effect on the stability of rapids in the canyons of the Green River in Dinosaur National Monument 68 km (42 mi) downstream from the dam. The reduction in peak flows by the dam has limited the competence of the river to move boulders deposited in the main channel by tributary processes, landslides, and prehistoric floods. Before the dam …

Issues Concerning Phreatophyte Clearing, Revegetation, And Water Savings Along The Gila River, Arizona, William Graf, Duncan Patten, Bonnie Turner

William L. Graf

A detailed analysis of the published results of the U. S. Geological Survey Phreatophyte Project conducted in the area of interest for the Corps of Engineers Camelsback Dam study provides the following results. It appears that the figure of 18.53 inches per year for water savings from phreatophyte clearing along the Gila River in southeast Arizona should not be used for predicting potential water salvage because of large sampling errors, measurement errors, and the inherent variability of the natural processes of evapotranspiration. An extensive literature review shows that no dependable values are available for the Gila River project area. It …

Partially Materialized Digest Scheme: An Efficient Verification Method For Outsourced Databases, Kyriakos Mouratidis, Dimitris Sacharidis, Hwee Hwa Pang

Kyriakos MOURATIDIS

In the outsourced database model, a data owner publishes her database through a third-party server; i.e., the server hosts the data and answers user queries on behalf of the owner. Since the server may not be trusted, or may be compromised, users need a means to verify that answers received are both authentic and complete, i.e., that the returned data have not been tampered with, and that no qualifying results have been omitted. We propose a result verification approach for one-dimensional queries, called Partially Materialized Digest scheme (PMD), that applies to both static and dynamic databases. PMD uses separate indexes …

Pre-Disaster Risk Management In Post-Earthquake (1999) Turkey, Engin Erdem

ENGIN I ERDEM Dr.

This paper assesses the status of pre-disaster risk management in the case of Turkey. By focusing on the period following the catastrophic August 17, 1999 earthquake, the study benefits from USAID’s Disaster Risk Management Benchmarking Tool (DRMBT). In line with the benchmarking tool, the paper covers key developments in the four components of pre-disaster risk management, namely: risk identification, risk mitigation, risk transfer and disaster preparedness. In the end, it will present three major conclusions: (i) Although post-1999 Turkey has made some important progress in the pre-disaster phase of DRM, particularly with the enactment of obligatory earthquake insurance and tightened …

Brave New World: Myth And Migration In Recent Asian-Australian Picture Books, Wenche Ommundsen

Wenche Ommundsen

From Exodus to the American Dream, from Terra Nullius to the Yellow Peril to multicultural harmony, migration has provided a rich source of myth throughout human history. It engenders dreams, fears and memories in both migrant and resident populations; giving rise to hope for a new start and a bright future, feelings of exile and alienation, nostalgia for lost homelands, dreams of belonging and entitlement, fears of invasion, dispossession and cultural extinction. It has inspired artists and writers from the time of the Ancient Testament to the contemporary age of globalisation and mass migration and it has exercised the minds …

Bandwagon, Underdog, And Political Competition: The Uni-Dimensional Case, Woojin Lee

Woojin Lee

The present paper studies the effects of bandwagon and underdog on the political equilibrium of two-party competition models. We adapt the generalized Wittman-Roemer model of political competition for voter conformism, which views political competition as the one between parties with factions of the opportunists and the militants that Nash-bargain one another, and consider three special cases of the general model: the Hotelling-Downs model, the classical Wittman-Roemer model, and what we call the ideological-party model. In the Hotelling-Downs model, where the militants have no bargaining power in both parties, political parties put forth an identical policy at the equilibrium, regardless of …