Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Role Of Dietary Modification In Alleviating Chronic Fatigue Syndrome Symptoms: A Systematic Review, Kathryn Jones, Yasmine Probst
Role Of Dietary Modification In Alleviating Chronic Fatigue Syndrome Symptoms: A Systematic Review, Kathryn Jones, Yasmine Probst
Faculty of Science, Medicine and Health - Papers: part A
Objective: To review the evidence for the role of dietary modifications in alleviating chronic fatigue syndrome symptoms. Methods: A systematic literature review was guided by PRISMA and conducted using Scopus, CINAHL Plus, Web of Science and PsycINFO scientific databases (1994-2016) to identify relevant studies. Twenty-two studies met the inclusion criteria, the quality of each paper was assessed and data extracted into a standardised tabular format. Results: Positive outcomes were highlighted in some included studies for polyphenol intakes in animal studies, D-ribose supplementation in humans and aspects of symptom alleviation for one of three polynutrient supplement studies. Omega three fatty acid …
Diterpenoid Alkaloids Of Aconitum Laciniatum And Mitigation Of Inflammation By 14-O-Acetylneoline In A Murine Model Of Ulcerative Colitis, Phurpa Wangchuk, Severine Navarro, Catherine Shepherd, Paul A. Keller, Stephen G. Pyne, Alex Loukas
Diterpenoid Alkaloids Of Aconitum Laciniatum And Mitigation Of Inflammation By 14-O-Acetylneoline In A Murine Model Of Ulcerative Colitis, Phurpa Wangchuk, Severine Navarro, Catherine Shepherd, Paul A. Keller, Stephen G. Pyne, Alex Loukas
Faculty of Science, Medicine and Health - Papers: part A
Aconitum laciniatum is used in Bhutanese traditional medicine for treating various chronic infections and inflammatory conditions. We carried out in-depth isolation and characterization of the phytochemicals from the root component and determined the anti-inflammatory effects of the isolated compounds against chemically-induced colitis in mice. Five diterpenoid alkaloids - pseudaconitine, 14-veratroylpseudaconine, 14-O-acetylneoline, neoline, and senbusine A - were isolated from A. laciniatum for the first time. Two of the alkaloids were tested for anti-inflammatory properties in the TNBS-induced colitis model in mice. Various parameters were measured to assess pathology including weight loss, clinical and macroscopic scores, histological structure and IFN-γ production …