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Racial Differences In The Association Of Insulin Resistance With Risk Of Incident Heart Failure In Participants Of Regards, Nirav Patel
All ETDs from UAB
Background: Insulin resistance is linked to the development of heart failure (HF). However, there is limited understanding of the racial differences in the association of insulin resistance with the risk of incident HF among individuals without diabetes. Objectives: In a US national cohort of Black and White participants, we sought to evaluate: 1) the relationship between insulin resistance with incident HF participants, and 2) whether there are racial differences in the association of insulin resistance with HF. Methods: We examined >16,000 participants without HF and diabetes at baseline from the REGARDS cohort. Cox regression modeling was used to assess the …
An Analysis Of Preterm Birth Related To Sars-Cov-2 Infection By Race, Madeleine B. Mcgwin
An Analysis Of Preterm Birth Related To Sars-Cov-2 Infection By Race, Madeleine B. Mcgwin
All ETDs from UAB
Research investigating the association between pregnant women with COVID-19 infection and adverse birth outcomes, including preterm birth, having been contradicting. Individual differences between study populations, e.g., racial composition, may explain some of these inconsistencies. The aim of the present study is to determine if the association between SARS-CoV-2 infection and pre-term birth varies according to race. A cross-sectional study was conducted using data from the Vizient Clinical Data Base/Research Manager (CDB/RM). The study participants were women who gave birth in one of the Vizient facilities between March 2020 and January 2021. A positive COVID-19 test status was the primary exposure …
Heart Failure In A Contemporary Biracial Cohort, Matthew Mefford
Heart Failure In A Contemporary Biracial Cohort, Matthew Mefford
All ETDs from UAB
Heart failure (HF) is the inability of the heart to meet the perfusion needs of the body. HF is a leading contributor to the burden of cardiovascular disease (CVD) and remains a public health concern. Hypertension is a major modifiable risk factor for the prevention and management of HF. Hypertension develops earlier, is less controlled, and has a stronger association with some CVD and renal outcomes among blacks versus whites. These disparities may extend to HF. In addition, adults with HF often have complex treatment regimens due to multimorbidity, making medication adherence an issue. The goal of this dissertation was …