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Vitamin D Status Is Not Associated With Risk Of Early Menopause, Alexandra C. Purdue-Smith, Brian W. Whitcomb, Joann E. Manson, Susan E. Hankinson, Lisa M. Troy, Bernard A. Rosner, Elizabeth R. Bertone-Johnson

Biostatistics and Epidemiology Faculty Publications Series

Background: Early natural menopause, the cessation of ovarian function before age 45 y, is positively associated with cardiovascular disease and other conditions. Dietary vitamin D intake has been inversely associated with early menopause; however, no previous studies have evaluated risk with regard to plasma 25-hydroxyvitamin D [25(OH)D] concentrations.

Objective: We prospectively evaluated associations of total and free 25(OH)D and vitamin D–binding protein (VDBP) concentrations and the risk of early menopause in a case-control study nested within the Nurses’ Health Study II (NHS2). We also considered associations of 25(OH)D and VDBP with anti-Müllerian hormone (AMH) concentrations.

Methods: The NHS2 is a …

The Importance Of Friends And Family To Recreational Gambling, At-Risk Gambling, And Problem Gambling, Alissa Mazar, Robert J. Williams, Edward J. Stanek Iii, Martha Zorn, Rachel A. Volberg

Biostatistics and Epidemiology Faculty Publications Series

Background

The variables correlated with problem gambling are routinely assessed and fairly well established. However, problem gamblers were all ‘at-risk’ and ‘recreational’ gamblers at some point. Thus, it is instructive from a prevention perspective to also understand the variables which discriminate between recreational gambling and at-risk gambling and whether they are similar or different to the ones correlated with problem gambling. This is the purpose of the present study.

Method

Between September 2013 to May 2014, a representative sample of 9,523 Massachusetts adults was administered a comprehensive survey of their past year gambling behavior and problem gambling symptomatology. Based on …