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Virtual And In Vitro Screening Of Natural Products Identifies Indole And Benzene Derivatives As Inhibitors Of Sars-Cov-2 Main Protease (MPro), Dony Ang, Riley Kendall, Hagop S. Atamian Mar 2023

Virtual And In Vitro Screening Of Natural Products Identifies Indole And Benzene Derivatives As Inhibitors Of Sars-Cov-2 Main Protease (MPro), Dony Ang, Riley Kendall, Hagop S. Atamian

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The rapid spread of the coronavirus disease 2019 (COVID-19) resulted in serious health, social, and economic consequences. While the development of effective vaccines substantially reduced the severity of symptoms and the associated deaths, we still urgently need effective drugs to further reduce the number of casualties associated with SARS-CoV-2 infections. Machine learning methods both improved and sped up all the different stages of the drug discovery processes by performing complex analyses with enormous datasets. Natural products (NPs) have been used for treating diseases and infections for thousands of years and represent a valuable resource for drug discovery when combined with …


Extreme Development Of Dragon Fruit Agriculture With Nighttime Lighting In Southern Vietnam, Shenyue Jia, Son V. Nghiem, Seung-Hee Kim, Laura Krauser, Andrea E. Gaughan, Forest R. Stevens, Menas Kafatos, Khanh D. Ngo Mar 2022

Extreme Development Of Dragon Fruit Agriculture With Nighttime Lighting In Southern Vietnam, Shenyue Jia, Son V. Nghiem, Seung-Hee Kim, Laura Krauser, Andrea E. Gaughan, Forest R. Stevens, Menas Kafatos, Khanh D. Ngo

Institute for ECHO Faculty Books and Book Chapters

Dragon fruit is widely grown in Southeast Asia and other tropical or subtropical regions. As a high-value cash crop ideal for exportation, dragon fruit cultivation has boomed during the past decade in southern Vietnam. Light supplementing during the winter months using artificial lighting sources is a widely adopted cultivation technique to boost productivity in the major dragon fruit planting regions of Vietnam. The application of electric lighting at night leads to a significant increase of nighttime light (NTL) observable by satellite sensors. The strong seasonality signal of NTL in dragon fruit cultivation enables identifying dragon fruit plantations using NTL images. …


Air Quality Over Major Cities Of Saudi Arabia During Hajj Periods Of 2019 And 2020, Ashraf Farahat, Akshansha Chauhan, Mohammed Al Otaibi, Ramesh P. Singh Feb 2021

Air Quality Over Major Cities Of Saudi Arabia During Hajj Periods Of 2019 And 2020, Ashraf Farahat, Akshansha Chauhan, Mohammed Al Otaibi, Ramesh P. Singh

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Mecca and Madinah are two holy cities where millions of people in general, visit throughout the years, during Hajj (Muslim's pilgrimage) time number of people visit these holy cities from different parts of the world is very high. However, the Government of Saudi Arabia only allowed 1000 pilgrims during the 2020 Hajj especially when the world is suffering from COVID-19. In the present paper, a detailed analysis of air quality parameters available from ground measurements have been carried over major cities of Saudi Arabia, Mecca, Madinah, and Jeddah from June to September 2019 and 2020. At Mecca and Jeddah, PM …


Effect Of Lockdown On Hcho And Trace Gases Over India During March 2020, Akshansha Chauhan, Ramesh P. Singh Nov 2020

Effect Of Lockdown On Hcho And Trace Gases Over India During March 2020, Akshansha Chauhan, Ramesh P. Singh

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

COVID-19 is one of the deadly Epidemics that has impacted people living in more than 200 countries. In order to mitigate the impact of COVID-19, India observed total lockdown in the first phase for a period of 21 days (24 March–13 May 2020), so that social distancing is maintained. However, this sudden decision severely affected the normal life of people. The air quality improved due to lockdown, some relaxation was given in different cities and within some areas in the city where the people were not affected by COVID-19. In this paper, we discuss results of detailed analysis of trace …


Investigating The Significance Of Aerosols In Determining The Coronavirus Fatality Rate Among Three European Countries, Wenzhao Li, Rejoice Thomas, Hesham El-Askary, Thomas Piechota, Daniele Struppa, Khaled A. Abdel Ghaffar Sep 2020

Investigating The Significance Of Aerosols In Determining The Coronavirus Fatality Rate Among Three European Countries, Wenzhao Li, Rejoice Thomas, Hesham El-Askary, Thomas Piechota, Daniele Struppa, Khaled A. Abdel Ghaffar

Mathematics, Physics, and Computer Science Faculty Articles and Research

The coronavirus pandemic has not only gripped the scientific community in the search for a vaccine or a cure but also in attempts using statistics and association analysis—to identify environmental factors that increase its potency. A study by Ogen (Sci Total Environ 726:138605, 2020a) explored the possible correlation between coronavirus fatality and high nitrogen dioxide exposure in four European countries—France, Germany, Italy and Spain. Meanwhile, another study showed the importance of nitrogen dioxide along with population density in determining the coronavirus pandemic rate in England. In this follow-up study, Aerosol Optical Depth (AOD) was introduced in conjunction with other variables …