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Oral Medicine and Surgical Sciences Issue (Oral Medicine, Oral and Maxillofacial Surgery, Oral Pathology, Oral Biology)
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Role Of Stem Cells In Transport Distraction Osteogenesis For Reconstruction Of Mandibular Defects After Segmental Mandibulectomy, Fatma Alzhraa Yousef, Susan Hassan, Fatma Mohammed, Wael Shawkat
Role Of Stem Cells In Transport Distraction Osteogenesis For Reconstruction Of Mandibular Defects After Segmental Mandibulectomy, Fatma Alzhraa Yousef, Susan Hassan, Fatma Mohammed, Wael Shawkat
Al-Azhar Journal of Dentistry
Purpose: to restore the continuity and functions of the mandible after segmental mandibulectomy for mandibular defect reconstruction by using a technique of transport distraction osteogenesis with stem cells injection. Subjects and methods: Clinical study was conducted on eight patients suffering from mandibular deficiency after tumor resection. All steps of manufacturing of the transport distractor, tumor resection and segmental mandibulectomy of transport disc were guided by Stereolithographic (STL) model. Stem cells sample was prepared to be injected along the soft callus at the end of the activation period. Patients were followed up postoperative clinically every week and radiographically by Panoramic x-ray …
Evaluation Of Anti-Carcinogenic Effect Of Selenium Nanoparticles On Induced Oral Squamous Cell Carcinoma, Aya Yehia, Amany Taha, Eman Abo Hager
Evaluation Of Anti-Carcinogenic Effect Of Selenium Nanoparticles On Induced Oral Squamous Cell Carcinoma, Aya Yehia, Amany Taha, Eman Abo Hager
Al-Azhar Journal of Dentistry
Purpose: Current study proposed to estimate the anticarcinogenic influence of Selenium Nanoparticles (SeNps) on induced squamous cell carcinoma utilizing caspase3 as an apoptotic marker. Material and Methods: Thirty hamsters were used, divided into four groups. Group I: 2 hamsters were left untreated, Group II: 8 hamsters received SeNPs orally for 14 weeks at dosage of 0.5 mg/kg on alternative day along the experimental period. Group III: 10 hamsters received Dimethylbenz [a]anthracene (DMBA) (0.5%) painted by brush on the buccal pouch 3 times per week for 8 weeks, then received DMBA with 5-Fluorouracil (5-FU) for another 6 weeks twice a week …
Correlation Between Clinical And Radiographic Evaluation Using Custom-Made Newly Developed Software Program As A Guide For Accurate Diagnosis Of Periodontal Diseases, Eman Hassan, Naglaa El-Kilani, Halaa Hazza
Correlation Between Clinical And Radiographic Evaluation Using Custom-Made Newly Developed Software Program As A Guide For Accurate Diagnosis Of Periodontal Diseases, Eman Hassan, Naglaa El-Kilani, Halaa Hazza
Al-Azhar Journal of Dentistry
Purpose: to correlate between clinical and radiographic findings using custom– made newly developed software program that guide clinicians, for accurate diagnosis. This is based on clinical and radiographic data from 3D volumetric rendering of cone beam computed tomography. This has been done based on the new classification of periodontal diseases (of 2018). Materials and methods: A randomized clinical study was performed on hundred and fifty patients with periodontal diseases of both gender with age range (30-60) years old. Periodontal clinical parameters were taken. Radiographic analysis using CBCT and 3D volumetric rendering was done. Results: There is a moderate positive correlation …
Use Of Injectable Hyaluronic Acid Gel And Injectable Platelet-Rich Fibrin In The Treatment Of Gingival Black Triangles: A Randomized Clinical Trial, Ingy Fakher, Hala Hazzaa, Nora Abdelgawad
Use Of Injectable Hyaluronic Acid Gel And Injectable Platelet-Rich Fibrin In The Treatment Of Gingival Black Triangles: A Randomized Clinical Trial, Ingy Fakher, Hala Hazzaa, Nora Abdelgawad
Al-Azhar Journal of Dentistry
Purpose: The current study aimed to compare the efficacy of injectable hyaluronic acid gel and injectable platelet rich fibrin, either alone or combined; for the reconstruction of defective interdental papilla using clinical approaches. Subjects and Methods: A total sample size of eighteen class I and class II deficient interdental papillae sites were randomly divided in 3 groups. Group 1 included 6 sites that were treated by 0.2ml hyaluronic acid gel injection. Group 2 included 6 sites that were treated by injectable platelet-rich fibrin (i-PRF). Group 3 included 6 sites that were treated by a combination of 0.2ml hyaluronic acid gel …
A Comparative In Vitro Study: Cytotoxicity Effect Of Curcumin Vs Biodegradable Nanoparticles/Pva Against Hno97 And Effect Of Curcumin On Cell Cycle Phases, Sara Denewer
Al-Azhar Journal of Dentistry
Purpose: This study evaluated that curcumin and biodegradable nanoparticles with PVA as capping material, in terms of cytotoxicity followed by cell cycle analysis against the HNO97 cell line (tongue carcinoma). Material and methods: 5mg of pure curcumin, 7.5 mg of Nano curcumin formulation, and SRB for IC50 done on five concentrations. A flow cytometry test was carried on to evaluate the effect of curcumin on the HNO97 cell line. Results: This study postulated that curcumin had the highest cytotoxicity effect against cell line (HNO97) with IC50=1.59 µg/ml in comparison to curcumin nanoparticles/PVA showed low cytotoxicity owing to the pH (7.4) …
Effect Of Polycaprolactone Nanofiber Membrane Versus Concentrated Growth Factor On Periodontal Ligament Model Defect, Ola Dewedar, Heba Adawy, Mai Attia, Mena Abdullah
Effect Of Polycaprolactone Nanofiber Membrane Versus Concentrated Growth Factor On Periodontal Ligament Model Defect, Ola Dewedar, Heba Adawy, Mai Attia, Mena Abdullah
Al-Azhar Journal of Dentistry
Purpose: This study was carried out to evaluate the effect of two different regenerative materials on periodontal Ligament Model Defect through histological examination of rabbit’s mandible. Material and Methods: Thirty-six (36) adult male New Zealand rabbits (weight 3 to 3.5 kg) were used and then divided randomly into 3 groups according to material received (n=12).Group I (GI) control group that did not receive any treatment, Group II (GII) that received polycarolactone nanofiber membrane (PCL), Group III (GIII) that received concentrated growth factor membrane (CGF), surgical procedures were done to create a bony defect of 5x5mm size in the right side …
Use Of Injectable Hyaluronic Acid Gel And Injectable Platelet-Rich Fibrin In The Treatment Of Gingival Black Triangles: A Randomized Clinical Trial, Ingy Fakher, Hala Hazzaa, Nora Abdelgawad
Use Of Injectable Hyaluronic Acid Gel And Injectable Platelet-Rich Fibrin In The Treatment Of Gingival Black Triangles: A Randomized Clinical Trial, Ingy Fakher, Hala Hazzaa, Nora Abdelgawad
Al-Azhar Journal of Dentistry
Purpose: The current study aimed to compare the efficacy of injectable hyaluronic acid gel and injectable platelet rich fibrin, either alone or combined; for the reconstruction of defective interdental papilla using clinical approaches. Subjects and Methods: A total sample size of eighteen class I and class II deficient interdental papillae sites were randomly divided in 3 groups. Group 1 included 6 sites that were treated by 0.2ml hyaluronic acid gel injection. Group 2 included 6 sites that were treated by injectable platelet-rich fibrin (i-PRF). Group 3 included 6 sites that were treated by a combination of 0.2ml hyaluronic acid gel …
A Comparative In Vitro Study: Cytotoxicity Effect Of Curcumin Vs Biodegradable Nanoparticles/Pva Against Hno97 And Effect Of Curcumin On Cell Cycle Phases, Sara Denewer
Al-Azhar Journal of Dentistry
Purpose: This study evaluated that curcumin and biodegradable nanoparticles with PVA as capping material, in terms of cytotoxicity followed by cell cycle analysis against the HNO97 cell line (tongue carcinoma). Material and methods: 5mg of pure curcumin, 7.5 mg of Nano curcumin formulation, and SRB for IC50 done on five concentrations. A flow cytometry test was carried on to evaluate the effect of curcumin on the HNO97 cell line. Results: This study postulated that curcumin had the highest cytotoxicity effect against cell line (HNO97) with IC50=1.59 µg/ml in comparison to curcumin nanoparticles/PVA showed low cytotoxicity owing to the pH (7.4) …
Evaluation Of Anti-Carcinogenic Effect Of Selenium Nanoparticles On Induced Oral Squamous Cell Carcinoma, Aya Yehia, Amany Taha, Eman Abo Hager
Evaluation Of Anti-Carcinogenic Effect Of Selenium Nanoparticles On Induced Oral Squamous Cell Carcinoma, Aya Yehia, Amany Taha, Eman Abo Hager
Al-Azhar Journal of Dentistry
Purpose: Current study proposed to estimate the anticarcinogenic influence of Selenium Nanoparticles (SeNps) on induced squamous cell carcinoma utilizing caspase3 as an apoptotic marker. Material and Methods: Thirty hamsters were used, divided into four groups. Group I: 2 hamsters were left untreated, Group II: 8 hamsters received SeNPs orally for 14 weeks at dosage of 0.5 mg/kg on alternative day along the experimental period. Group III: 10 hamsters received Dimethylbenz [a]anthracene (DMBA) (0.5%) painted by brush on the buccal pouch 3 times per week for 8 weeks, then received DMBA with 5-Fluorouracil (5-FU) for another 6 weeks twice a week …
Role Of Stem Cells In Transport Distraction Osteogenesis For Reconstruction Of Mandibular Defects After Segmental Mandibulectomy, Fatma Alzhraa Yousef, Susan Hassan, Fatma Mohammed, Wael Shawkat
Role Of Stem Cells In Transport Distraction Osteogenesis For Reconstruction Of Mandibular Defects After Segmental Mandibulectomy, Fatma Alzhraa Yousef, Susan Hassan, Fatma Mohammed, Wael Shawkat
Al-Azhar Journal of Dentistry
Purpose: to restore the continuity and functions of the mandible after segmental mandibulectomy for mandibular defect reconstruction by using a technique of transport distraction osteogenesis with stem cells injection. Subjects and methods: Clinical study was conducted on eight patients suffering from mandibular deficiency after tumor resection. All steps of manufacturing of the transport distractor, tumor resection and segmental mandibulectomy of transport disc were guided by Stereolithographic (STL) model. Stem cells sample was prepared to be injected along the soft callus at the end of the activation period. Patients were followed up postoperative clinically every week and radiographically by Panoramic x-ray …
Effect Of Polycaprolactone Nanofiber Membrane Versus Concentrated Growth Factor On Periodontal Ligament Model Defect, Ola Dewedar, Heba Adawy, Mai Attia, Mena Abdullah
Effect Of Polycaprolactone Nanofiber Membrane Versus Concentrated Growth Factor On Periodontal Ligament Model Defect, Ola Dewedar, Heba Adawy, Mai Attia, Mena Abdullah
Al-Azhar Journal of Dentistry
Purpose: This study was carried out to evaluate the effect of two different regenerative materials on periodontal Ligament Model Defect through histological examination of rabbit’s mandible. Material and Methods: Thirty-six (36) adult male New Zealand rabbits (weight 3 to 3.5 kg) were used and then divided randomly into 3 groups according to material received (n=12).Group I (GI) control group that did not receive any treatment, Group II (GII) that received polycarolactone nanofiber membrane (PCL), Group III (GIII) that received concentrated growth factor membrane (CGF), surgical procedures were done to create a bony defect of 5x5mm size in the right side …
Correlation Between Clinical And Radiographic Evaluation Using Custom-Made Newly Developed Software Program As A Guide For Accurate Diagnosis Of Periodontal Diseases, Eman Hassan, Naglaa El-Kilani, Halaa Hazza
Correlation Between Clinical And Radiographic Evaluation Using Custom-Made Newly Developed Software Program As A Guide For Accurate Diagnosis Of Periodontal Diseases, Eman Hassan, Naglaa El-Kilani, Halaa Hazza
Al-Azhar Journal of Dentistry
Purpose: to correlate between clinical and radiographic findings using custom– made newly developed software program that guide clinicians, for accurate diagnosis. This is based on clinical and radiographic data from 3D volumetric rendering of cone beam computed tomography. This has been done based on the new classification of periodontal diseases (of 2018). Materials and methods: A randomized clinical study was performed on hundred and fifty patients with periodontal diseases of both gender with age range (30-60) years old. Periodontal clinical parameters were taken. Radiographic analysis using CBCT and 3D volumetric rendering was done. Results: There is a moderate positive correlation …
The Effect Of Psychological Stress On Periodontal Disease During Covid-19 Virus Threat: Relation To Salivary Prostaglandin (Pge2), Samah Helmy, Hamdy Nassar, Omnia Ahmed
The Effect Of Psychological Stress On Periodontal Disease During Covid-19 Virus Threat: Relation To Salivary Prostaglandin (Pge2), Samah Helmy, Hamdy Nassar, Omnia Ahmed
Al-Azhar Journal of Dentistry
Purpose: The current study aimed to evaluate the impact of the stress on the periodontium and its clinical features present in the oral cavity, also to measure the PGE2 present in saliva and its effect on the periodontal disease. Subjects and Methods: A total number of thirty health care providers were involved in the study. They were passing through heavy physiological issues during theCOVID-19 pandemic threats. The study consisted of three phases. First phase the clinical periodontal evaluation which included assessment of Gingival index (GI), probing depth (PD) and clinical attachment level (CAL).Second phase the psychological stress was assessed via …
Radiographic Assessment Of Buccolingual Dimension Of Allogenic Bone Ring When Used Simultaneously With Dental Implant Placement, Hussein Elrawy, Hatem Al-Ahmady, Fayez Safadi
Radiographic Assessment Of Buccolingual Dimension Of Allogenic Bone Ring When Used Simultaneously With Dental Implant Placement, Hussein Elrawy, Hatem Al-Ahmady, Fayez Safadi
Al-Azhar Journal of Dentistry
Purpose: This study aimed to evaluate the use of allogenic bone ring technique to restore the bucco-lingual dimension of the alveolar bone defects combined with simultaneous dental implant placement. Subjects and methods: Ten patients requiring bone augmentation horizontally or both horizontally and vertically at the time of implant placement were included in this retrospective study. All patients received simultaneous bone augmentation surgery and implant placement with allogenic bone ring grafts. Postoperative efficacy of the technique was evaluated using CBCT as a radiographical parameter. Results: Survival rates of implants were 100%. Cone-beam computed tomography revealed that the allogenic bone ring graft …
Molecular Assessment Of Kallikrein 3 In Ameloblastoma And Odontogenic Keratocyst, Kholoud Ahmed, Mohamed El Sebie, Nadia Radi, Amal Abd El Rahman, Eman Abohager
Molecular Assessment Of Kallikrein 3 In Ameloblastoma And Odontogenic Keratocyst, Kholoud Ahmed, Mohamed El Sebie, Nadia Radi, Amal Abd El Rahman, Eman Abohager
Al-Azhar Journal of Dentistry
Purpose: The current research was conducted to assess KLK3 at molecular and protein level in AB and OKC to shed more light on its role on biologic behaviour of these lesions. Material and methods: 30 paraffin embedded blocks of AB, OKC and Dentigerous Cyst (DC) as a control were included. Immunohistochemical staining technique with KLK3 antibody was applied to all the tissue blocks and RT-PCR KLK3 gene were done for all specimens. Results: The mean area percent of KLK3 expression was significantly greater in AB and OKC compared with DC. According to the current study, presence of significant difference between …
The Effect Of Psychological Stress On Periodontal Disease During Covid-19 Virus Threat: Relation To Salivary Immunoglobulin A (Siga), Hala Sayed, Hamdy Nassar, Nora Abd El-Gawad
The Effect Of Psychological Stress On Periodontal Disease During Covid-19 Virus Threat: Relation To Salivary Immunoglobulin A (Siga), Hala Sayed, Hamdy Nassar, Nora Abd El-Gawad
Al-Azhar Journal of Dentistry
Purpose: The present study aimed to examine serum cortisol concentrations and salivary immunoglobulin A (S-IgA) levels under psychological stress during the COVID-19 virus threat and its relationship to periodontal condition. Materials and methods: A total of 30 participants who had particularly high scores on the perceived stress scale (PSS) were involved in this study. Psychological stress was assessed via the PSS questionnaire. The Clinical periodontal evaluation included assessment of gingival index (GI), probing depth (PD) and clinical attachment level (CAL). Biochemical quantification of serum cortisol concentrations and S-IgA levels was performed using the enzyme-linked immunosorbent assays method (ELIZA). Every step …
The Effect Of Human Demineralized Dentin Matrix Scaffold Alone And Combined With Concentrated Growth Factor On Bone Repair In Rabbits, Somaya Mostafa, Mena Abd Allah, Heba Adawy
The Effect Of Human Demineralized Dentin Matrix Scaffold Alone And Combined With Concentrated Growth Factor On Bone Repair In Rabbits, Somaya Mostafa, Mena Abd Allah, Heba Adawy
Al-Azhar Journal of Dentistry
Purpose: This study aimed to evaluate the potential effect of Human Demineralized Dentin Scaffold (HDDS) alone and when combined with Concentrated Growth Factor (CGF) on repair of bony defects in the tibia of rabbits, histologically, by using scanning electron microscope and computed tomography. Materials and Methods: Ten adult male rabbits (weight 2 to 2.5 kg) were used in this study. Ethics committee approval of Faculty of Dental Medicine For Girls as obtained with code number (REC-BI-19-01). In each rabbit two holes were created (one in each tibia). In five rabbits, the first control hole was left empty and the second …
Correction Of Gummy Smile By Surgical Lip Repositioning With Myotomy Versus Botox Injection Technique, Karima Ali, Naglaa El-Kilanni, Mai Attia
Correction Of Gummy Smile By Surgical Lip Repositioning With Myotomy Versus Botox Injection Technique, Karima Ali, Naglaa El-Kilanni, Mai Attia
Al-Azhar Journal of Dentistry
Purpose: This study aimed to compare surgical lip repositioning with myotomy and Botox injection in treatment of patients with excessive gingival display. Subjects and Methods: A sample of 10 female patients with age range (19-42) yearold with excessive gingival display greater than 2 mm were randomly allocated into 2 groups, Group I: patients were treated with surgical lip repositioning with myotomy. Group II: patients were treated with Botox injection. Treatment changes were evaluated for each group and compared between groups. Data were collected and analyzed using paired t-test for each group and student t-test to compare between groups at baseline, …
Photodynamic Periodontal Therapy Vs. Diode Laser As An Adjunctive To Conventional Periodontal Treatment In Management Of Chronic Periodontitis, Marwa Mohammed, Osama El-Shall, Nora Mohammed
Photodynamic Periodontal Therapy Vs. Diode Laser As An Adjunctive To Conventional Periodontal Treatment In Management Of Chronic Periodontitis, Marwa Mohammed, Osama El-Shall, Nora Mohammed
Al-Azhar Journal of Dentistry
Purpose: This study was made to evaluate and compare the efficacy of photodynamic periodontal therapy and diode laser as an adjunctive approach to conventional periodontal therapy in management of chronic periodontitis. Subjects and methods: 30 patients with chronic periodontitis and age range from 30-40 years old were divided randomly into three groups. Group I (control group) 10 patients received conventional periodontal therapy alone. Group II (laser group): patients received SRP + additional application of a 940-nm diode laser. Group III (photodynamic group): patients received SRP + antimicrobial photodynamic therapy by using low level 670 nm diode laser application in addition …
Evaluation Of Glutathione Levels In Gingival Cervical Fluid In Periodontitis From Stage 1 – Stage 4 Among Type 2 Diabetic Patients, Maha Elsayed, Mai Attia, Zienab Farid
Evaluation Of Glutathione Levels In Gingival Cervical Fluid In Periodontitis From Stage 1 – Stage 4 Among Type 2 Diabetic Patients, Maha Elsayed, Mai Attia, Zienab Farid
Al-Azhar Journal of Dentistry
Purpose: This study aimed to evaluate if glutathione could be used as a diagnostic biomarker in diabetic patients with stage 1, stage 2, stage 3, and stage 4 periodontitis who were receiving non-surgical periodontal therapy. Material and methods: Twentyeight participants were included, who were separated into four groups, each with seven members. Seven diabetic patients with stage 1 periodontitis were assigned to Group 1, seven diabetic patients with stage 2 periodontitis were assigned to Group 2, and seven diabetic patients with stage 3 periodontitis were assigned to Group 3 and Seven diabetic patients with stage 4 periodontitis were assigned to …