Digital Commons Network^™

Disuse-Induced Muscle Atrophy And Muscle Weakness From Hospitalization To Spaceflight: Exercise Succeeds In Prevention And Treatment—A Meta-Analysis, Camila S. Padilha, Figueiredo, Rafael Deminice, S. Ribeiro, Robert U. Newton, Nicolas H. Hart, José Cesar Rosa-Neto, Marília Seelaender, Fábio Santos Lira

Research outputs 2022 to 2026

Background: Exercise has been proposed as both a preventive and therapeutic countermeasure; however, its effectiveness across different disuse conditions and timings of implementation remains uncertain. Methods: This systematic review and meta-analysis (PROSPERO: CRD42021256599) searched ClinicalTrials.gov, Cochrane Central, PubMed, SPORTDiscus, Web of Science, Scopus, CINAHL and SciELO from inception to May 2021, with an update in March 2025. Randomized and nonrandomized controlled trials examining exercise interventions during or after muscle disuse were included according to the PICOS framework. Random-effects meta-analysis evaluated effects on muscle strength, power and mass across hospitalization, bed rest and spaceflight conditions. Effect sizes (ES) are reported as …

Issues That Ministers Identify As Factors Contributing To Anxiety And Depression, Heather Sawtelle

Doctor of Ministry (DMin)

Although mental health is an emerging topic within the church community, the stigmatization of mental illness within ministers’ lives can create a myriad of personal beliefs that can lead to shame and discontent in ministers’ lives. Many ministers have daily stressors that compromise their mental health, and these stressors can contribute to depression or anxiety. This study defined mental health issues and described mental illness’ influence on ministers’ lives and the factors that contribute to mental health issues. This health condition, described as mental illness, involves significant changes in thinking, emotion, behavior, distress, and problems functioning in social, work, or …

The Effect Of A Dynamic Lighting Schedule On Neurobehavioral Performance During A 45-Day Simulated Space Mission, Leilah Grant, Brianne Kent, Shadab Rahman, Melissa St Hilaire, Crystal Kirkley, Kevin Gregory, Toni Clark, John Hanifin, Laura Barger, Charles Czeisler, George Brainard, Steven Lockley, Erin Flynn-Evans

Department of Neurology Faculty Papers

Study Objective: We previously reported that during a 45-day simulated space mission, a dynamic lighting schedule (DLS) improved circadian phase alignment and performance assessed once on selected days. This study aimed to evaluate how DLS affected performance on a 5-minute psychomotor vigilance task (PVT) administered multiple times per day on selected days.

Methods: Sixteen crewmembers (37.4 ± 6.7 years; 5F) underwent six cycles of 2 × 8-hour/night followed by 5 × 5-hour/night sleep opportunities. During the DLS (n = 8), daytime white light exposure was blue-enriched (∼6000 K; Level 1: 1079, Level 2: 76 melanopic equivalent daytime illuminance (melEDI) lux) …

Preparation For Implementation Of Evidence-Based Practices In Urban Schools: A Shared Process With Implementing Partners., Ricardo Eiraldi, Rachel Comly, Courtney Benjamin Wolk, Quinn Rabenau-Mcdonnell, Barry Mccurdy, Muniya S Khanna, Abbas F Jawad, Jayme Banks, Stacina Clark, Kristina M Popkin, Tara Wilson, Kathryn Henson

PCOM Scholarly Works

BACKGROUND: Shifting organizational priorities can negatively affect the sustainment of innovations in community settings. Shifting priorities can present barriers to conducting clinical research in schools if a misalignment occurs between school district priorities and the aims of the study. Often this misalignment occurs due to a shift during the period between when the study is submitted for funding and when research activities begin. Participatory research approaches can be employed to restore alignment between study processes and school district priorities. The purpose of the study is to describe data from a shared process with district partners. The shared process resulted in …

Social Determinants Of Health And Disparities In Hypertension And Cardiovascular Diseases, Abhishek Chaturvedi, Anqi Zhu, Naga Vaishnav Gadela, Dorairaj Prabhakaran, Tazeen Jafar

Department of Medicine

High blood pressure causes over 10 million preventable deaths annually globally. Populations in low- and middle-income countries suffer the most, experiencing increased uncontrolled blood pressure and cardiovascular disease (CVD) deaths. Despite improvements in high-income countries, disparities persist, notably in the United States, where Black individuals face up to 4× higher CVD mortality than White individuals. Social determinants of health encompass complex, multidimensional factors linked to an individual's birthplace, upbringing, activities, residence, workplaces, socioeconomic and environmental structures, and significantly affect health outcomes, including hypertension and CVD. This review explored how social determinants of health drive disparities in hypertension and related CVD …

“I Want Justice From People Who Did Bad Things To Children”: Experiences Of Justice For Sex Trafficking Survivors, John G. Morrissey, James Havey, Glenn M. Miles, Nhanh Channtha, Lim Vanntheary

Dignity: A Journal of Analysis of Exploitation and Violence

This research from the Butterfly Longitudinal Research Project focused on understanding the experiences and perceptions of justice and the justice system for 93 Cambodia participants (including 88 survivors of sex trafficking) as they navigated the legal system. Thirty-two of these survivors had experiences in court and provided details into their courtroom experiences, predominantly within Cambodia but also in the United States. The survivors’ experiences were diverse; however, the prevailing themes were: fear throughout their legal journeys; a low level of awareness and understanding of their legal experiences; and that NGO support was essential for these survivors to engage in the …

“I Don’T Want The Next Generation Of Children To Be In Pain Like Me”: The Chab Dai Ten-Year Butterfly Longitudinal Research Project On Sex Trafficking Survivors In Cambodia, Glenn M. Miles, James Havey, Siobhan Miles, Eliza Piano, Lim Vanntheary, Nhanh Channtha, Sreang Phaly, Ou Sopheara

Dignity: A Journal of Analysis of Exploitation and Violence

The Butterfly Longitudinal Research Project started in 2010 and is the only research project of its kind listening to sex trafficking victims over ten years. The project was started in Cambodia by Chab Dai (translated “Hands Together”), a coalition of Non-Government Organisations since 2006 who have focused on human trafficking. The project was founded with the express purpose of listening to the survivors’ voices and recording their experiences in order to better understand their physical, emotional and spiritual needs during their initial recovery in shelters and reintegration back into their communities. The team of researchers and the participants, all of …

"When They See Someone Who Is Poor, They Step On Them": The Social Determinants Of Health Among Survivors Of Sex Trafficking In Cambodia, James P. Havey, Glenn M. Miles, Lim Vanntheary, Nhanh Channtha, Hanni Stoklosa

Dignity: A Journal of Analysis of Exploitation and Violence

Social determinants of health (SDH) are defined as the non-medical yet health-affecting conditions of a person’s life. They include such considerations as working conditions, discrimination, and access to health services. The aim of this study was to explore the SDH impacting those who have survived sex trafficking in Cambodia. This study employed a mixed methods, secondary analysis, focusing on 52 survivors of sex trafficking in the Butterfly Longitudinal Research Project from 2010 through 2019. Participants described myriad social determinants of health, including: gender, age, relationship status (marriage), ethnicity, national identification documentation (statelessness), social class, formal education, vocational training, occupation, and …

"There Is Always Violence": An Exploratory Study Of Phnom Penh, Cambodia, Street-Involved Children, Jarrett D. Davis, Glenn M. Miles, Sean Blackburn, Erika Mosebach-Kornelsen

Dignity: A Journal of Analysis of Exploitation and Violence

As the economic center of Cambodia, Phnom Penh has long been a hotspot for street-involved children and families. While violence is a common facet of life on the street, risk and vulnerability among children is notoriously difficult to measure. Most large-scale surveys tend to sample children within homes and schools, which overlook street-involved children who are commonly unregistered, irregularly attend school, and live outside of houses. This research paper is one of a series of studies on such groups in Southeast Asia. The study conducted 94 semi-structured interviews with street-involved children eight to 18 years of age in Phnom Penh. …

Microbiome For Mars: Surveying Microbiome Connections To Healthcare With Implications For Long-Duration Human Spaceflight, Virtual Workshop, July 13, 2020, Michael Lapelusa, Dorit Donoviel, Sergio E Branzini, Paul E Carlson, Stephanie Culler, Amrita K Cheema, Rima Kaddurah-Daouk, Denise Kelly, Isabelle De Cremoux, Rob Knight, Rosa Krajmalnik-Brown, Stephen L Mayo, Sarkis K Mazmanian, Emeran A Mayer, Joseph F Petrosino, Keith Garrison

Faculty, Staff and Students Publications

The inaugural "Microbiome for Mars" virtual workshop took place on July 13, 2020. This event assembled leaders in microbiome research and development to discuss their work and how it may relate to long-duration human space travel. The conference focused on surveying current microbiome research, future endeavors, and how this growing field could broadly impact human health and space exploration. This report summarizes each speaker's presentation in the order presented at the workshop.

Safety And Efficacy Of Bioidentical Hormone Therapy In Menopause: A Literature Review, Kathryn Akre

All Graduate Theses, Dissertations, and Other Capstone Projects

Vasomotor symptoms (VMS) experienced during menopause can negatively impact a woman’s quality of life, productivity, sleep, and mood. Systemic hormone therapy (HT) is the most effective treatment for moderate to severe VMS, however safety concerns raised by the 2002 Women’s Health Initiative (WHI) trial have led to a decrease in overall HT use and a growing demand for custom-compounded bioidentical HT. Misconceptions regarding the superior safety and efficacy of custom-compounded hormones and lack of clinician expertise in menopause management contribute to ongoing uncertainty and low uptake of United States (U.S.) Food and Drug Administration (FDA) approved bioidentical HT products. This …

Creating A Culture Of Teamwork And Communication, Ikjae Yang

Master's Projects and Capstones

This paper aims to explain an innovative strategy for integrating research processes and quality improvement in a medical/ surgical telemetry unit (2 North). The project is targeted to improve health care team communication regarding patient safety to improve patient outcomes. The PICO question guiding this project stated: Does the implementation of TeamSTEPPS during orientation improve communication and teamwork? CINAHL database searched terms "TeamSTEPPS", "new graduate nurses", "communication", "healthcare", "teamwork", and TeamSTEPPS effectiveness. In addition to CINAHL, Google Scholar and PubMed databases were used to narrow down database searches.

The project includes a TeamSTEPPS planning guide that offers the planning organization, …

Sex And Gender In Research On Healthcare Workers In Conflict Settings: A Scoping Review, Dana A. Halwani, Diana Mikati, Layal Hneiny

Faculty Publications

The occupational health literature has established that sex and gender are associated with all dimensions of the workplace. Sex and/or gender (sex/gender) factors play an important role in shaping the experiences, exposures, and health outcomes of male and female healthcare providers working in war and conflict settings. This study aims to (1) assess how sex/gender is considered in the occupational health literature on healthcare workers in conflict settings, and (2) identify the gaps in incorporating sex/gender concepts in this literature. A scoping review was carried out and nine electronic databases were searched using a comprehensive search strategy. Two reviewers screened …

Maternal Viral Load Monitoring: Coverage And Clinical Action At 4 Kenyan Hospitals., Matthew Sandbulte, Melinda Brown, Catherine Wexler, May Maloba, Brad Gautney, Kathy Goggin, Elizabeth Muchoki, Shadrack Babu, Nicodemus Maosa, Sarah Finocchario-Kessler

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Kenya's guidelines for prevention of mother-to-child transmission of HIV (PMTCT) recommend routine viral load (VL) monitoring for pregnant and breastfeeding women.

METHOD: We assessed PMTCT VL monitoring and clinical action occurring between last menstrual period (LMP) and 6 months postpartum at 4 Kenyan government hospitals. Pregnant women enrolled in the HIV Infant Tracking System from May 2016-March 2018 were included. We computed proportions who received VL testing within recommended timeframes and who received clinical action after unsuppressed VL result.

RESULTS: Of 424 participants, any VL testing was documented for 305 (72%) women and repeat VL testing was documented for …

Combating Pediatric Obesity With A Community-Based, Family-Centered Pediatric Obesity Prevention Program, Hillary Mayers, Msn, Fnp-C

Doctor of Nursing Practice Projects

Background: Overweight and obesity among children contributes to significant adverse health outcomes that reduce quality of life. Because children are influenced by the behaviors of their parents, there is a need for multicomponent family-based interventions within the community to help overcome these issues.

Objectives: This quality improvement project provided parents and children aged four to six years old with an interactive nutrition and physical activity educational program to increase their knowledge related to healthy lifestyle patterns and alter BMI status.

Methods: A 10-week pre/posttest design was implemented to evaluate outcome measures including BMI percentile, physical activity and nutritional habits, and …

Influenza A Viruses In Peridomestic Mammals, J. Jeffrey Root, Susan A. Shriner

United States Department of Agriculture Wildlife Services: Staff Publications

During recent years, serological evidence has shown that a number of peridomestic mammals (e.g., those commonly found in or around human structures) are naturally exposed to influenza A viruses (IAVs). In addition, experimental studies have demonstrated that many of these species can successfully replicate several different IAVs, including IAVs of high consequence to public or agricultural health. The replication of some IAVs within this group of mammals could have implications for biosecurity associated with poultry production and live bird markets in some regions of the world. Given this evidence, the need for further study and understanding of the role that …

Women’S Experiences With Epilepsy Treatment In Southern India: A Focused Ethnography, Jane R. Von Gaudecker 3172782758, Ann Gill Taylor, Janice M. Buelow, Sailas Benjamin, Claire B. Draucker

The Qualitative Report

Women with epilepsy in rural southern India often do not receive anti-epilepsy drugs (AEDs) or take these drugs regularly, but little is known about how they experience the epilepsy treatment they do receive. The purpose of this study was to provide an in-depth description of the treatment experiences of women in this region who had been diagnosed with epilepsy but who do not consistently take AEDs. Focused ethnography was conducted using participant observation and in-depth interviews with six women with epilepsy, eight of their family members, and two traditional healers. The women’s treatment experiences are best described as living at …

Simulating Human-Robot Teamwork Dynamics For Evaluation Of Work Strategies In Human-Robot Teams, Martijin Ijtsma, Sean Ye, Karen M. Feigh, Amy Pritchett

International Symposium on Aviation Psychology - 2019

To foster resilience in teams operating in complex work domains, design should allow for a range of work strategies as appropriate to context. This paper describes how computational simulation and network visualization of a team’s work can identify feasible work strategies and assess their appropriateness for different contexts. Network visualizations can identify constraints and dependencies that drive the feasible set of work strategies. After preliminary network analysis, these dependencies and inter-dependencies can be simulated in detail to better understand their impact. To illustrate, we describe a case study that explores two different work strategies that can each address the dependencies …

Dimensions Of Nurse-Physician Communication, Rachel Malek Hamdan

Walden Dissertations and Doctoral Studies

Hospital leaders set quality and safety as high priorities in their strategic goals. Improving the quality and safety of patient care requires improving internal processes that have direct implications for patient care. Hospital leaders need to improve health care providers' communication as part of improving quality and safety. The problem addressed in this study was the lack of strategies health care administrators use to guide nurse-physician communication patterns in a university medical center in the Middle East. The purpose of this qualitative case study was to explore communication strategies that health care administrators use to guide nurse-physician communication. Relational coordination …

Predicting Desired Outcomes From Applicants’ Medical School Admission Data, Mark D. Linville Jr.

Electronic Theses and Dissertations

Medical schools in the United States serve to train the next generation of physicians, admitting students who will continue to advance each school’s mission. Admission committees are tasked with identifying those candidates who will be successful academically and who promote the objectives of the school with respect to mission. The Quillen College of Medicine at East Tennessee State University in northeast Tennessee seeks to attract and retain physicians with an interest in rural and primary care medicine. A total of 630 students were included in this study representing classes from 2001 to 2011. This study examined admissions data including MCAT …

Synthesizing Data And Models For The Spread Of Mers-Cov, 2013: Key Role Of Index Cases And Hospital Transmission, Gerardo Chowell, Seth Blumberg, Lone Simonsen, Mark A. Miller, Cecile Viboud

Global Health Faculty Publications

The outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) has caused 209 deaths and 699 laboratory-confirmed cases in the Arabian Peninsula as of June 11, 2014. Preparedness efforts are hampered by considerable uncertainty about the nature and intensity of human-to-human transmission, with previous reproduction number estimates ranging from 0.4 to 1.5. Here we synthesize epidemiological data and transmission models for the MERS-CoV outbreak during April–October 2013 to resolve uncertainties in epidemic risk, while considering the impact of observation bias. We match the progression of MERS-CoV cases in 2013 to a dynamic transmission model that incorporates community and hospital compartments, and …

Church-Based Alcohol Rehabilitation In The Former Soviet Union, Mark R. Elliott

Occasional Papers on Religion in Eastern Europe

No abstract provided.

Santa Clara Magazine, Volume 53 Number 3, Winter 2012, Santa Clara University

Santa Clara Magazine

18 - MY FIGHT, MY FAITH By Steven Boyd Saum. As head of the CIA, Leon Panetta '60, J.D. '63 restored confidence in the agency and oversaw the mission to find Osama bin Laden. Now, as secretary of defense in an age of budget austerity, he has to make sure the Pentagon doesn't break the bank-and that the nation doesn't break faith with the men and women who serve.

24 - GENERAL JOE By Sam Scott '96. When Joseph Peterson '72 signed up for ROTC as an undergrad, he planned to complete his military service and then move on. Nearly …

Risk Factors Associated With Hepatitis C Among Female Substance Users Enrolled In Communitybased Hiv Prevention Studies, Diana Nurutdinova, Arbi B. Abdallah, Susan Bradford, Catina C. O'Leary, Linda B. Cottler

Open Access Publications

No abstract provided.

Correlates Of Distances Traveled To Use Recreational Facilities For Physical Activity Behaviors, Gavin R. Mccormack, Billie Giles-Corti, Max K. Bulsara, Terri J. Pikora

Medical Papers and Journal Articles

Background: Information regarding how far people are willing to travel to use destinations for different types of recreational physical activity behaviors is limited. This study examines the demographic characteristics, neighborhood opportunity and specific-physical activity behaviors associated with distances traveled to destinations used for recreational physical activity.

Methods: A secondary analysis was undertaken of data (n = 1006) from a survey of Western Australian adults. Road network distances between respondents' homes and 1) formal recreational facilities; 2) beaches and rivers; and 3) parks and ovals used for physical activity were determined. Associations between distances to destinations and demographic characteristics, neighborhood opportunity …

Tribal Wisdom For Today’S World, H Sudarshan

IIMB Management Review

No abstract provided.

Experimental Deer-To-Deer Transmission Of Mycobacterium Bovis, Mitchell V. Palmer, Diana L. Whipple, W. Ray Waters

Michigan Bovine Tuberculosis Bibliography and Database

Objective—To determine whether Mycobacterium bovis can be transmitted from experimentally infected deer to uninfected in-contact deer.

Animals—Twenty-three 6-month-old white-tailed deer.

Procedure—On day 0, M bovis (2 X 10⁸ colony-forming units) was administered by intratonsillar instillation to 8 deer; 3 control deer received saline (0.9% NaCl) solution. Eight in-contact deer were comingled with inoculated deer from day 21. On day 120, inoculated deer were euthanatized and necropsied. On day 180, 4 in-contact deer were euthanatized, and 4 new incontact deer were introduced. On day 360, all in-contact deer were euthanatized. Rectal, oral, and nasal swab specimens and …

Modification Of Sand Fly Biting Behavior By Leishmania Leads To Increased Parasite Transmission, Raymond Beach, Gabriel Kjilu, Johannis Leeuwenberg

Harold W. Manter Laboratory of Parasitology: Library Materials

To attempt rodent-sand fly-rodent transmission of Leishmania major, laboratory-reared Phlebotomus doboscqi were fed on L. major-infected mice and then refed on uninfected mice 21 days later. Flies which refed either probed 1–2 times and took a full blood meal in less than 10 minutes or probed 3 or more times and took little or no blood during a period of 15 minutes or more. When dissected, 7 of 8 flies which experienced difficulty in obtaining a blood meal had flagellates in their cibaria, an observation supporting the hypothesis that parasites in this part of the alimentary canal modify normal …

Health Problems Of Selected Lds Missionaries Throughout The World, Susan Jensen

Theses and Dissertations

The purpose of this study on Mormon missionaries was to determine the effect of health on missionary activity time, age, sex, months in field, laboring city population, monthly mission cost, living conditions, diet, pre-existing conditions, adequacy of medical care, nativity, effectiveness, emotional health, interpersonal relationships, and motivation and enthusiasm. In addition the research attempted to ascertain the effect of the selected independent factors on ill missionary lost time.

As an outcome of the statistical analysis performed on this study's sample the following results were obtained. Respiratory disorders, gastrointestinal difficulties and orthopedic injuries were the most common health problems. Well missionaries …