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Articles 1 - 30 of 1639
Full-Text Articles in Entire DC Network
Transmutation Of Psychological Phenomena (Academic Burnout And Fomo) Into Cyanotype Art Creation, Zulfan Ali Mujtaba, Adi Kuntoro
Transmutation Of Psychological Phenomena (Academic Burnout And Fomo) Into Cyanotype Art Creation, Zulfan Ali Mujtaba, Adi Kuntoro
Paradigma: Jurnal Kajian Budaya
The pressure of hustle culture and the Fear of Missing Out (FOMO) in the digital era have triggered an escalation of academic burnout among students, demanding alternative psychological recovery interventions beyond verbal clinical approaches. This research aims to explore the creation of alternative Cyanotype photography as a medium for catharsis and resistance against toxic productivity. Utilizing a Practice-Based Research methodology with an autoethnographic approach, data were extracted from the researcher's subjective experiences and transmuted into a visual artifact titled "Metamorfosis yang Lelah". The cultural studies approach and wabi-sabi aesthetics are specifically applied to analyze visual elements in the Prussian Blue …
Determinants Of Antenatal Care Utilization: A Community-Based, Cross-Sectional Study In Morang And Sunsari Districts, Eastern Nepal, Sunil Shah, Chandra Jha
Determinants Of Antenatal Care Utilization: A Community-Based, Cross-Sectional Study In Morang And Sunsari Districts, Eastern Nepal, Sunil Shah, Chandra Jha
Journal of Social, Behavioral, and Health Sciences
This study examined the factors influencing antenatal care (ANC) utilization in the eastern region of Nepal, focusing on the Morang and Sunsari districts, with the aim of identifying key determinants affecting ANC uptake and assessing the extent of ANC service utilization among mothers. Using lot quality assurance sampling, a community-based, descriptive, cross-sectional design was employed, surveying 164 mothers who had given birth within the previous 12 months; data were collected from June through November 2023. Data were collected through a semi-structured questionnaire and analyzed using SPSS, with descriptive statistics, chi-square tests, and logistic regression. Findings revealed that 80.5% of respondents …
Relational Reasoning Across Cultures: Consistency And Variation In South Korea, The United States, And China, Alexandra Carstensen, Minju Kim, Youngon Choi, Caren M. Walker
Relational Reasoning Across Cultures: Consistency And Variation In South Korea, The United States, And China, Alexandra Carstensen, Minju Kim, Youngon Choi, Caren M. Walker
Psychology Faculty Articles and Research
Abstract reasoning in early childhood is often described as following a “relational shift,” over which children become increasingly sensitive to relations. However, recent work has challenged the generality of this account, showing that children in the US and China follow distinct trajectories in a relational match-to-sample task. This difference aligns with multiple cultural and linguistic factors implicated in relational reasoning, where the US and China appear at opposite ends of a continuum, focusing on objects (US) versus relations (CN). This raises the possibility that differences in culture and language may shape variation in the development of abstract reasoning. Here, we …
The Chameleon Experience: Queer Identity, Mental Health, And Transformation, Cameron Penny
The Chameleon Experience: Queer Identity, Mental Health, And Transformation, Cameron Penny
Communication and Theater Association of Minnesota Journal
In this autoethnographic piece, I examine the correlation between queer identity and mental health through reflective analysis of my own experiences within a Western socio-cultural setting. I expand external perspectives on the queer experience by highlighting the normalization of queer prejudice and its adverse impact on self-image. I share how the religious praxis of Catholicism enforces binary conformity by promoting dichotomous thinking that simultaneously constricts queer expression and subjugates implicit biases. In tandem, I utilize autoethnography as my medium because it provides a unique outlet to raise awareness for chronically stigmatized identities by centering marginalized voices (Atay, 2011; Chavez, 2013). …
Perceived Trustworthiness As A Pathway Linking Adhd Traits To Large Language Models Dependency: Evidence From Uk And Chinese Samples, Ala Yankouskaya, Mohammad Amin Kuhail, Haibo Yang, Xiaokun Wang, Jiaojiao Chen, Tina Yunsi Ma, Sameha Alshakhsi, Guandong Xu, Raian Ali
Perceived Trustworthiness As A Pathway Linking Adhd Traits To Large Language Models Dependency: Evidence From Uk And Chinese Samples, Ala Yankouskaya, Mohammad Amin Kuhail, Haibo Yang, Xiaokun Wang, Jiaojiao Chen, Tina Yunsi Ma, Sameha Alshakhsi, Guandong Xu, Raian Ali
All Works
Large language models (LLMs) create contexts in which individual differences may shape reliance on digital systems. Drawing on neurodiversity, this study examined whether perceived trustworthiness of user’s primary LLM mediates associations between attention-deficit/hyperactivity disorder (ADHD) traits and LMM dependencyinstrumental and relationship LLM dependency. Adults in the UK (n = 567) and China (n = 577) reported ADHD traits, perceived LLM trustworthiness of LLM, and both types of dependency. Across samples, higher ADHD traits were associated with lower trustworthiness, whereas greater trustworthiness was associated with greater instrumental and relationship dependency, yielding negative indirect effects. In the UK, direct ADHD-dependency associations were …
Quantitative Imaging Of Pyruvate Metabolism In A Patient With Anaplastic Thyroid Cancer, James A Bankson, Joshua S Niedzielski, Collin J Harlan, Yunyun Chen, Christopher M Walker, Philip L Lorenzi, Lin Tan, Vikas Kundra, Matthew E Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B Peterson, Clifton D Fuller, Vlad C Sandulache, Stephen Y Lai
Quantitative Imaging Of Pyruvate Metabolism In A Patient With Anaplastic Thyroid Cancer, James A Bankson, Joshua S Niedzielski, Collin J Harlan, Yunyun Chen, Christopher M Walker, Philip L Lorenzi, Lin Tan, Vikas Kundra, Matthew E Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B Peterson, Clifton D Fuller, Vlad C Sandulache, Stephen Y Lai
Faculty, Staff and Students Publications
Purpose: Magnetic resonance imaging using hyperpolarized (HP) [1-13C]-pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi-quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular metabolism. A validated pharmacokinetic (PK) model for analysis of intracellular pyruvate metabolism is needed to enhance the accuracy of quantitative metrics and clinical translation of metabolic MRI using HP pyruvate.
Methods: A PK model with two physical compartments and two chemical pools was developed to analyze the conversion of labeled pyruvate into lactate in vitro. …
Perspectives Of Scholars, Families, And Advisors On 360-Degree Video Technology In Graduate Education, Oluwatobi A. Mogbojuri, Bridget A. Walsh, Matthew Aguirre
Perspectives Of Scholars, Families, And Advisors On 360-Degree Video Technology In Graduate Education, Oluwatobi A. Mogbojuri, Bridget A. Walsh, Matthew Aguirre
Journal of Human Sciences and Extension
This study explored the experiences of scholars in creating and sharing 360-degree videos, as well as the perspectives of families and advisors who viewed the videos. Focus groups and individual interviews were conducted online using a videoconferencing platform. Perspectives from 20 participants (15 scholars, three advisors, and two family members) were analyzed using thematic analysis. Three primary themes were identified: (1) barriers to 360-degree video use, (2) perspective shifts and limited change, and (3) storytelling and scholar visibility. Findings suggest that 360-degree video technology may be an innovative tool for enhancing recruitment and retention, especially for historically marginalized groups, through …
Exploring Primary Care Providers’ Compassionate Care And Their Evidence-Based Practice With Death, Grief, And Loss: Patient Experience And Perspective, Kathryn Krzykala
Exploring Primary Care Providers’ Compassionate Care And Their Evidence-Based Practice With Death, Grief, And Loss: Patient Experience And Perspective, Kathryn Krzykala
Dissertations
Research on primary care providers’ (PCPs) education regarding Death, Grief, and Loss (DGL) remains limited. Specifically, data is lacking regarding patients' perceptions and opinions on what they need and expect from their PCPs regarding grief and loss. This exploratory mixed-method study comprised 146 participants who had experienced death and non-death loss. It examined participants' perceptions of 1) PCP compassion, 2) PCP utilization of evidence-based grief and loss practices, 3) their own level of comfort discussing DGL with their PCPs during medical visits, and 4) their personal grief and loss experiences. The findings revealed that PCPs' grief-informed evidence-based treatment, as reflected …
Prmt5 As A Key Driver Of Stemness And Metastatic Potential In Triple-Negative Breast Cancer, Jae Jin Jeong, Mauli Maniar, Shahrzad Ghane, Sakshi Deshpande, Claire Ellis, Ashakumary Lakshmikuttyamma
Prmt5 As A Key Driver Of Stemness And Metastatic Potential In Triple-Negative Breast Cancer, Jae Jin Jeong, Mauli Maniar, Shahrzad Ghane, Sakshi Deshpande, Claire Ellis, Ashakumary Lakshmikuttyamma
College of Pharmacy Faculty Papers
Protein arginine methyltransferase 5 (PRMT5) mediates arginine methylation of a wide range of proteins and plays context-dependent oncogenic or tumor-suppressive roles. In cancer, PRMT5 represses several tumor suppressor genes, including E-cadherin, TP53BP1, ST7, PTEN, and RB (retinoblastoma). Elevated PRMT5 expression has been reported across multiple cancer types, notably triple-negative breast cancer (TNBC). In TNBC, high PRMT5 levels are associated with enhanced cancer stem cell self-renewal, increased tumor growth and metastasis, and reduced patient survival. Mechanistically, PRMT5 promotes breast cancer stem cell maintenance and proliferation through stabilization of the transcription factors KLF4 and KLF5. Disruption of the PRMT5-KLF4 axis results in …
Healthcare Access Challenges Among Asian Americans, Phyo Theingi
Healthcare Access Challenges Among Asian Americans, Phyo Theingi
University Honors Theses
Asian Americans are the fastest growing racial ethnic group in the U.S. According to the 2023 U.S. Census Bureau population estimate, Asian Americans account for 25.2 million (or 7.4%) of the nation's population. Asian Americans are not a monolith and represent a diversity of rich histories, cultures, languages and ethnicities. According to research conducted by the Pew Research Center, most Asian Americans face discrimination of some kind, including being treated as a foreigner in the U.S and being stereotyped as a model minority. They also experience health care access barriers. Research found that Asian Americans face barriers related to language …
Living Through Misinformation: An Autoethnography Of Autism In Chinese Communities, Joy Lu
Living Through Misinformation: An Autoethnography Of Autism In Chinese Communities, Joy Lu
Ought: The Journal of Autistic Culture
This critical autoethnographic essay examines how misconception, misinformation, and disinformation shape understandings of autism within Chinese communities and produce tangible harm for autistic individuals and their families. Drawing on lived experience, advocacy work, digital observation, and cross-cultural analysis, it explores how language, medical practices, social media, and professional authority sustain persistent misrepresentation.
The essay argues that this misinformation is not merely the result of ignorance, but a socially reinforced and institutionally supported system of knowledge. By situating personal encounters within broader cultural and structural contexts, it highlights the interconnected roles of language, power, and exclusion in shaping autistic lives. It …
Development And Validation Of The Lifetime Sense Of Safety Scale In Kenyan Adults, Karen Blackmon, Anne Nyambura, Anne Gitere, Levi Muyela, Catherine Onyancha, Kendi Muchungi, Catherine Ajalo, Litha Musili, Rachel Maina, Edna Bosire, Lukoye Atwoli, Zul Merali, Chinedu Momoh
Development And Validation Of The Lifetime Sense Of Safety Scale In Kenyan Adults, Karen Blackmon, Anne Nyambura, Anne Gitere, Levi Muyela, Catherine Onyancha, Kendi Muchungi, Catherine Ajalo, Litha Musili, Rachel Maina, Edna Bosire, Lukoye Atwoli, Zul Merali, Chinedu Momoh
Brain and Mind Institute
Background. Safety supports psychological wellbeing and potentially shapes brain aging yet existing scales overlook cumulative lifespan safety experiences.
Methods. To address this gap, we developed and validated the Lifetime Sense of Safety (LSS) scale in Kenyan adults. The LSS uses visual analog scaling with a red-to-green color gradient to retrospectively rate felt safety across life stages and settings. We evaluated scale psychometrics and associations with social determinants of health and indicators of brain health.
Results. The LSS shows adequate internal consistency and test-retest reliability, with two distinct but correlated factors representing childhood and adulthood safety. Women and …
Assessing The Influence Of Disability Views On Perceptions Of Hearing Aids Among Older Korean Adults, Stasha Lee
Assessing The Influence Of Disability Views On Perceptions Of Hearing Aids Among Older Korean Adults, Stasha Lee
Dissertations, Theses, and Capstone Projects
Background
Age-related hearing loss, also known as presbycusis, is highly prevalent among older adults, yet hearing aid adoption remains low, in part due to concerns about stigma and negative social perceptions. This study aimed to examine whether attitudes towards disabilities influence perceptions of individuals wearing hearing aids among older Korean adults. It also explored the potential effects of cultural identity and the age of the individual wearing the hearing aid on these perceptions.
Methods
Ten participants completed the Attitudes and Perspectives on Persons with Disabilities (APPD) questionnaire and rated 8 different images of individuals (one younger male and one older …
Implicit Attitudes Toward Hearing Aid Visibility: Conspicuous Versus Inconspicuous Hearing Aid Colors, Orly R. Ames
Implicit Attitudes Toward Hearing Aid Visibility: Conspicuous Versus Inconspicuous Hearing Aid Colors, Orly R. Ames
Dissertations, Theses, and Capstone Projects
Hearing aid stigma remains a significant barrier to treatment uptake, with device visibility frequently identified as a contributing factor. Although prior research has examined visibility in relation to hearing aid size and style, the role of color as a distinct aesthetic dimension has not been systematically investigated. The present study assessed whether hearing aid color affects implicit and explicit attitudes toward hearing aids and whether such evaluations differ across contexts. Twenty-six adults who were not current hearing aid users participated in an online quantitative multi-method study consisting of an Implicit Association Test (IAT) and self-report questionnaires. The IAT measured implicit …
Soft Power, Arab Media And Sports Mega Events: Coverage Of Fifa 2022 And Lessons For Future Arab Hosting, Lynne Kennedy, Maaira Shahbaz, Ala Al Rajabi
Soft Power, Arab Media And Sports Mega Events: Coverage Of Fifa 2022 And Lessons For Future Arab Hosting, Lynne Kennedy, Maaira Shahbaz, Ala Al Rajabi
All Works
Sport mega-events (SMEs) increasingly transcend athletic competition, functioning as strategic instruments for national identity formation, statecraft, and soft power projection. This dynamic is particularly pronounced in the Gulf, where Qatar’s successful hosting reignited regional rivalries and attracted unprecedented global scrutiny. While existing scholars have extensively examined Western media portrayals of SMEs, a notable gap remains for academic engagement with Gulf media. Dismissed as state-controlled and analytically lacking, we contend that such media offer a rich site for exploring how small states use media as soft power, to construct and contest legitimacy, identity, and global influence. This analysis suggests how state-aligned …
Thoughts From The Pit: Can Raving Change The World? A Literature Review Exploring Rave Culture As Expressive Arts Healing, Marissa Rose Renella
Thoughts From The Pit: Can Raving Change The World? A Literature Review Exploring Rave Culture As Expressive Arts Healing, Marissa Rose Renella
Expressive Therapies Theses
This literature review examines the structural and philosophical commonalities between expressive arts therapy (EXA) and rave culture. Drawing on scholarship from anthropology, cultural studies, health sciences, transpersonal psychology, neuroscience, and expressive arts therapy, this review identifies five core principles shared between the two fields: transformational experiences, multimodality, entrainment and flow, containment and ritual, and community and social action values. Across each principle, the literature reveals not surface-level similarity but deep convergence — two fields that have, independently and through different lineages, arrived at the same understanding of what human beings need in order to heal, grow, and connect. To the …
From Cranes To Clinics: Genomic Epidemiology At The Human-Animal Interface, Sarah Shrum
From Cranes To Clinics: Genomic Epidemiology At The Human-Animal Interface, Sarah Shrum
Biology ETDs
Emerging infectious diseases represent a significant, increasing threat to human life, economic stability, and global security. The One Health framework, which promotes human health and wellness through the understanding that animal, environmental, and human health are interwoven, is critical to understanding pathogen emergence and transmission. This is underscored by the fact that roughly 60% of all human pathogens and 75% of emerging infectious disease are zoonotic, meaning they are transmitted from animals to humans.
The work presented in this dissertation integrates genomic epidemiology, ecological analysis, and One Health Surveillance approaches to characterize cross-species circulation of opportunistic yeast pathogens (Candida …
Using Group Activities To Improve Engagement And Help Alleviate Loneliness Among Older Adults At Macedonia Face, Taylor Corcoran
Using Group Activities To Improve Engagement And Help Alleviate Loneliness Among Older Adults At Macedonia Face, Taylor Corcoran
Public Health Capstone Projects
Introduction: Social isolation and loneliness are increasing public health concerns due to their association with heightened risk for chronic disease and their disproportionate impact on Black older adults (BOA). This project was designed to develop, implement, and evaluate the effectiveness of culturally relevant, low-cost activities on engagement rates among older adults during unscheduled program periods at the Macedonia Family Community Enrichment Center (FACE).
Methods: This project used a mixed methods approach over a 4-week implementation period. Three activities were introduced by the student facilitator, including UNO!, Name That Tune (NTT), and coloring pages. Engagement was measured by comparing the …
Exploring Stem Cell-Based Approaches To Ameloblast-Like Cell Development: Progress And Limitations In Enamel Formation, Ava L. Abruzzese
Exploring Stem Cell-Based Approaches To Ameloblast-Like Cell Development: Progress And Limitations In Enamel Formation, Ava L. Abruzzese
Honors Scholar Theses
Enamel is one of the most critical structural components of the tooth. As the outermost layer, it serves as a protective barrier, shielding the underlying dentin and dental pulp from physical trauma and mechanical forces. The formation and mineralization of enamel are regulated by specialized cells known as ameloblasts. Once enamel maturation is complete, these cells undergo apoptosis. Consequently, enamel lacks the capacity for natural regeneration after damage or erosion, which can result from various environmental factors. When enamel is compromised, current clinical interventions focus on preventing further deterioration rather than true regeneration. These approaches include the use of remineralizing …
A Literature Review Of Estrogen Synthesis And Metabolizing Enzymes Produced By The Human Gut Microbiome And Their Correlation With Cancer, Rebecca Cederberg
A Literature Review Of Estrogen Synthesis And Metabolizing Enzymes Produced By The Human Gut Microbiome And Their Correlation With Cancer, Rebecca Cederberg
Capstone Experience: Master of Public Health
The link between estrogen and cancer initiation or progression has been well established; such that the World Health Organization’s International Agency for Research on Cancer (WHO IARC) has classified several estrogen therapies and estrogenic compounds as group 1 carcinogens. Estrogen and/or its receptors have been associated with reproductive cancers such as breast, ovarian, endometrial, and prostate, as well as lymphomas, lung, and colon cancers. Additionally, elevated levels of estrogen and altered gut microbiomes are also associated with increased rates of breast cancer. More recently, microbial genes that are capable of synthesizing estrogen and deconjugating estrogen metabolites have been identified, and …
Artificial Intelligence In Dental Education: A Literature Review Of Global Adoption, Pedagogical Outcomes, And Ethical Implications, Betti Shahin, Jeremiah D. Ghodsi, Toleen Mazloum, Denise Hale
Artificial Intelligence In Dental Education: A Literature Review Of Global Adoption, Pedagogical Outcomes, And Ethical Implications, Betti Shahin, Jeremiah D. Ghodsi, Toleen Mazloum, Denise Hale
Journal of Educational Leadership in Action
Background: Artificial intelligence (AI) is revolutionizing many fields by enabling machines to accomplish tasks that previously required human intelligence, such as learning, decision-making, and problem-solving. In dentistry, AI is increasingly applied to diagnostics, treatment planning, and clinical training. Its integration enhances educational experiences for students while supporting more accurate and efficient patient care.
Objective: This review synthesizes recent research on AI in dental education, highlighting global adoption trends and key pedagogical, ethical, and practical considerations.
Conclusion: AI has significant potential to enhance dental education through innovative teaching, clinical training, and data-driven decision-making. Effective integration depends on institutional …
Neuropsychological Functioning And Coping Strategy Intervention Approaches In Youth With Posttraumatic Stress Disorder, Kalliopi Megari, Dimitra V. Katsarou, Georgios A. Kougioumtzis, Evangelos Mantsos, Maria Sofologi, Agathi Argyriadi, Alexandros Argyriadis, Efthymia Efthymiou
Neuropsychological Functioning And Coping Strategy Intervention Approaches In Youth With Posttraumatic Stress Disorder, Kalliopi Megari, Dimitra V. Katsarou, Georgios A. Kougioumtzis, Evangelos Mantsos, Maria Sofologi, Agathi Argyriadi, Alexandros Argyriadis, Efthymia Efthymiou
All Works
Background: Posttraumatic stress disorder (PTSD) in ages 3–18 is associated with disturbances in attention, working memory, processing speed, and executive control, as well as persistent difficulties in affect regulation. These neuropsychological vulnerabilities might interfere with learning, peer relationships, and the consolidation of age-appropriate developmental skills. Methods: We conducted a narrative review informed by a structured literature search in PubMed, Scopus, PsycINFO, Embase, EBSCOhost, Web of Science, and Google Scholar. English-language publications from 1990 to 2025 were considered if they examined (1) neuropsychological outcomes of trauma exposure or PTSD in youth and/or (2) interventions with potential to modify neurocognitive or affective …
Show And Tell: Integrating The Arts Into Transdisciplinary Public Health And Community Organizing Education, Bree L. Hemingway, Margaret Hawkins
Show And Tell: Integrating The Arts Into Transdisciplinary Public Health And Community Organizing Education, Bree L. Hemingway, Margaret Hawkins
The Transdisciplinary STEAM+ Journal
This field note examines the integration of arts-based pedagogy into a transdisciplinary graduate course that brings together students from public health, medicine, the social sciences, humanities, education, technology, and the arts. Central to the course is the Show and Tell assignment, in which students select and present a work of art connected to a social movement. Over three years and 42 student submissions, this assignment has served as an accessible entry point for exploring how artistic expression shapes activism, fosters community, and deepens understanding of justice-oriented work. Through an inductive content analysis of student-selected artworks and presentations, five major thematic …
Examining The Psychometric Properties Of The Big Three Perfectionism Scale–Short Form (Btps-Sf) Among Malaysian Chinese Students At A Private University, Kam-Fong Lee, Ashraf Sadat Ahadzadeh, Shin Ling Wu
Examining The Psychometric Properties Of The Big Three Perfectionism Scale–Short Form (Btps-Sf) Among Malaysian Chinese Students At A Private University, Kam-Fong Lee, Ashraf Sadat Ahadzadeh, Shin Ling Wu
Makara Journal of Health Research
Background: Perfectionism is increasingly prevalent among young adults and is a significant predictor of pathological and behavioral outcomes. Despite its relevance, validated and reliable measures of perfectionism tailored to university students, particularly within the Malaysian cultural and academic context, are lacking. This study addresses this gap by examining the psychometric properties of the BTPS-SF among Chinese students at a private university in Malaysia.
Methods: Data were collected using a cross-sectional design with convenience and snowball sampling from 380 students aged 18–25 years, predominantly from a Chinese student population.
Results: The results of the exploratory factor analysis, conducted …
Organizational Governance Capacity And Organizational Resilience In Hospitals: A Cross-Sectional Study, Leyla Afşar, Selim Yazıcı
Organizational Governance Capacity And Organizational Resilience In Hospitals: A Cross-Sectional Study, Leyla Afşar, Selim Yazıcı
Makara Journal of Health Research
Background: This study aims to examine the relationship between organizational governance capacity (OGC) and organizational resilience (OR) in hospitals, with a focus on cross-institutional differences.
Methods: A cross-sectional study was conducted among 1,143 employees from six hospital types in Istanbul, including university, Ministry of Health (state, training and research, and city), and private hospitals. Validated scales were used to measure OGC and OR. Data were analyzed using descriptive statistics, nonparametric tests, and structural equation modeling (SEM) to assess the relationships between these dimensions.
Results: Private hospitals demonstrated the highest levels of both OGC and OR (70%), followed …
Ethnicity, Culture, And The Epidemiology Of Eating Disorders, Rebecca Atwell
Ethnicity, Culture, And The Epidemiology Of Eating Disorders, Rebecca Atwell
Honors Theses
This systematic literature review addresses the research question: How does culture affect eating disorders? It examines the role of ethnicity and culture in shaping the prevalence, symptom presentation, and treatment of eating disorders across diverse populations. Although eating disorders have traditionally been studied in Western, predominantly White populations, growing evidence suggests that cultural norms, ethnic identity, globalization, and exposure to Western ideals significantly influence both the development and expression of disordered eating behaviors. Twenty peer-reviewed studies published between 2000 and 2024 were included. These studies were identified through systematic searches of PubMed, Scopus, Web of Science, and PsycINFO and selected …
Astrocyte Circadian Regulation In Neurodegeneration: In Vivo Bmal1 Occupancy Mapping Using Macs-Calling Cards, India Reiss
Astrocyte Circadian Regulation In Neurodegeneration: In Vivo Bmal1 Occupancy Mapping Using Macs-Calling Cards, India Reiss
Arts & Sciences Graduate Student Theses and Dissertations
Astrocytes maintain neuronal homeostasis through cellular programs that are frequently disrupted early in neurodegenerative disease, many of which are regulated by the circadian clock. The core clock transcription factor BMAL1 is required for normal astrocyte function, yet whether its regulatory activity is altered during neurodegeneration remains unclear. BMAL1 expression changes in disease are often inconsistent, suggesting that transcription factor binding, rather than expression, may be a more informative readout of BMAL1 function. We used a Cln3Δex7/8 model of neurodegeneration, which exhibits early astrocyte dysfunction prior to widespread neuronal loss, to test whether degenerative pathology reprograms BMAL1 binding in astrocytes. We …
Loss Of Znrf3/Rnf43 Unleashes Egrfr In Cancer, Fei Yue, Amy T Ku, Payton D Stevens, Megan N Michalski, Weiyu Jiang, Jianghua Tu, Zhongcheng Shi, Yongchao Dou, Yi Wang, Xin-Hua Feng, Galen Hostetter, Xiangwei Wu, Shixia Huang, Noah F Shroyer, Bing Zhang, Bart O Williams, Qingyun Liu, Xia Lin, Yi Li
Loss Of Znrf3/Rnf43 Unleashes Egrfr In Cancer, Fei Yue, Amy T Ku, Payton D Stevens, Megan N Michalski, Weiyu Jiang, Jianghua Tu, Zhongcheng Shi, Yongchao Dou, Yi Wang, Xin-Hua Feng, Galen Hostetter, Xiangwei Wu, Shixia Huang, Noah F Shroyer, Bing Zhang, Bart O Williams, Qingyun Liu, Xia Lin, Yi Li
Faculty, Staff and Students Publications
ZNRF3 and RNF43 are closely related transmembrane E3 ubiquitin ligases with significant roles in development and cancer. Conventionally, their biological functions have been associated with regulating WNT signaling receptor ubiquitination and degradation. However, our proteogenomic studies have revealed EGFR as the protein most negatively correlated with ZNRF3/RNF43 mRNA levels in multiple human cancers. Through biochemical investigations, we demonstrate that ZNRF3/RNF43 interact with EGFR via their extracellular domains, leading to EGFR ubiquitination and subsequent degradation facilitated by the E3 ligase RING domain. Overexpression of ZNRF3 reduces EGFR levels and suppresses cancer cell growth in vitro and in vivo, whereas knockout of …
Sociodemographic Factors And Dating Violence Among Adolescents Living In Rural Southern U.S. Communities, Kiara Patricia Sims-Thrasher
Sociodemographic Factors And Dating Violence Among Adolescents Living In Rural Southern U.S. Communities, Kiara Patricia Sims-Thrasher
Walden Dissertations and Doctoral Studies
Adolescent dating violence (ADV) is a significant public health issue that disproportionately affects youths in southern rural communities, yet these populations remain underrepresented in research. The purpose of this quantitative cross-sectional study was to examine the association between ADV and sociodemographic factors (gender, race, age, and education level), alcohol consumption, and bullying among adolescents in Alabama, Arkansas, and Mississippi using data from the 2021 Youth Risk Behavior Surveillance System. Guided by the social-ecological model, binary logistic regression analyses were conducted to assess relationships between ADV victimization and the selected predictors. Results indicated that females had significantly higher odds of reporting …
Bridging Cultures: Developing A Culturally Responsive Educational Website For Pediatric Service Providers, Aimun Aziz, Wendy Tremaine
Bridging Cultures: Developing A Culturally Responsive Educational Website For Pediatric Service Providers, Aimun Aziz, Wendy Tremaine
Spring 2026 OTD Capstone Symposium
The increasing cultural diversity of the pediatric population in the United States highlights the need for culturally responsive, family-centered care. However, many providers report limited training and practical resources to support the integration of cultural humility into clinical practice. This capstone project aimed to develop and evaluate an evidence-based educational website to support pediatric service providers in delivering culturally responsive care.
A program development framework was used, incorporating family needs assessments, pre- and post-intervention surveys of pediatric therapy staff, and thematic analysis of key factors related to communication, trust, and provider preparedness. Community field visits with diverse populations informed the …