Genetic Contributors Of Incident Stroke In 10,700 African Americans With Hypertension: A Meta-Analysis From The Genetics Of Hypertension Associated Treatments And Reasons For Geographic And Racial Differences In Stroke Studies, Nicole D. Armstrong, Vinodh Srinivasasainagendra, Amit Patki, Rikki M. Tanner, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Ethan M. Lange, Leslie A. Lange, Donna K. Arnett, Marguerite R. Irvin

Epidemiology and Environmental Health Faculty Publications

Background: African Americans (AAs) suffer a higher stroke burden due to hypertension. Identifying genetic contributors to stroke among AAs with hypertension is critical to understanding the genetic basis of the disease, as well as detecting at-risk individuals.

Methods: In a population comprising over 10,700 AAs treated for hypertension from the Genetics of Hypertension Associated Treatments (GenHAT) and Reasons for Geographic and Racial Differences in Stroke (REGARDS) studies, we performed an inverse variance-weighted meta-analysis of incident stroke. Additionally, we tested the predictive accuracy of a polygenic risk score (PRS) derived from a European ancestral population in both GenHAT and REGARDS AAs …

Providing Hypertension Education For African Immigrants At A Southern California Congregation During The Covid-19 Pandemic, Esther Oshunluyi

Doctor of Nursing Practice (DNP) Projects

Providing Hypertension Education for African Immigrants at a Southern California Congregation During the COVID-19 Pandemic

Abstract

Background: Hypertension (HTN) is one of the major risk factors for cardiovascular disease and the prevalence is highest among African Americans (AAs) (American Heart Association, 2017). The difference in the management and outcomes of HTN between African Americans and Whites is most disparate with lack of education being a major contributor to uncontrolled HTN among African Americans, especially among African Immigrants (Lackland, 2014).

Problem: According to church leadership at the project setting, the majority of their adult African Immigrant population is believed to have …

Mistrust, Neighborhood Deprivation, And Telehealth Use In African Americans With Diabetes., Barry W. Rovner, Robin J. Casten, Anna Marie Chang, Judd E. Hollander, Kristin Rising

Department of Emergency Medicine Faculty Papers

This study explored the relationship between trust in physicians and telehealth use during the COVID pandemic in 162 African Americans with diabetes. More than 90% of patients had internet-capable devices and internet service but only 61 patients (39%) had a telehealth visit. Compared to the latter, participants with no telehealth visits had less trust in physicians' ability to diagnose COVID, less trust in physicians' ability to treat via telehealth, and resided in more deprived neighborhoods. There were no differences in age, sex, education, nor literacy. For African Americans with diabetes, health disparities may increase unless fundamental issues such as trust …

Providing Hypertension Education To African Immigrants At A Southern California Congregation During The Covid-19 Pandemic, Esther Oshunluyi

Doctor of Nursing Practice (DNP) Projects

Objective: To review methods that could contribute to improved knowledge of hypertension among African immigrants at a California congregation. The difference in the management and outcomes of hypertension between African Americans and Whites is most disparate in cardiovascular disease, with lack of education documented as a major contributor for African Americans (Lackland, 2014) and African immigrants (Turson-Ocran et al., 2020). African Americans differ slightly in culture, health, and migration history from Africans who are 21st century immigrants from Africa (African immigrants); however, there are more similarities than differences between them (Terrazas, 2009). This brief report will describe a Doctor of …

The Role Of Healthcare Providers In Using The Knowledge Of Sickle Cell Trait To Mitigate Health Problems In African American Clients., Stella N. Udechukwu

Nicole Wertheim College of Nursing Student Projects

Abstract

Background: Sickle cell trait (SCT) for long has been regarded as a benign condition and as such healthcare providers do little to nothing to mitigate adverse health problems associated with sickle cell trait. An effective approach to improving health outcome for those with SCT is to educate providers on SCT, its complications and management. This study is aimed at evaluating the effectiveness of an educational intervention on providers’ knowledge, attitude and practice regarding sickle cell trait.

Method: A quasi experiment study was conducted in Jackson Health System on 30 providers belonging to internal medicine team to evaluate their …

The Effects Of A Faith-Based Diabetes Program For African Americans, Pandora Goode

International Journal of Faith Community Nursing

Purpose: The purpose of the study was to pilot test the effectiveness of a diabetes self-management program for African Americans with Type 2 Diabetes (T2D) in a group format in a faith-based setting. The rationale for the study was to create appropriate diabetes education in response to the growing diabetes prevalence among African Americans. The investigator hypothesized that after completing a 12-week program, participants would have improved diabetes knowledge, self-management practices, hemoglobin A1C, and an increase in self-efficacy. By reaching these goals, this program would contribute to one of the Healthy People 2020 objectives of increasing the proportion of …

Reproductive Justice And Black Lives: A Concept Analysis For Public Health Nursing, Kathryn Burger, Robin Evans‐Agnew, Susan L. Johnson

Nursing & Healthcare Leadership Publications

Inequities in maternal mortality in the US are a form of structural violence against Black women. The concept of reproductive justice has been employed in the social sciences for almost thirty years, yet nursing has been slow to adopt this concept in promoting maternal-child health. Objective: to analyze the concept of reproductive justice as used in peer-reviewed publications with the aim of reframing black maternal health in public health nursing scholarship, research, practice, and advocacy. Design: We conducted a systematic review of the social science literature. We analyzed selected articles though a principle-based concept analysis focusing on epistemological, pragmatic, linguistic, …

Barriers To Lung Cancer Screening Among African American Males Aged 50-70 In The United States, Edward Marines

Rowan-Virtua Research Day

Objectives:

• Identify the different barriers to lung cancer screening among African American males
• Examine potential methods of increasing access and participation within this population

Ethnic Differences In Maternal Cytokines And Adipokines And Their Association With Spontaneous Preterm Delivery, Yelizavet D. Lomakova, Xinhua Chen

Rowan-Virtua Research Day

Spontaneous preterm delivery (SPTD, birth at <37 weeks’ gestation) is a leading cause of infant mortality in the United States [1]. Infants born prematurely are more likely to suffer from both short and long-term complications including neurodevelopmental delay, visual and hearing impairment, and chronic diseases such as heart disease, hypertension and diabetes in later life [2-4]. African American women have a 2-fold increased risk of preterm delivery compared to Caucasian women [5].The reasons for this disparity are poorly understood. This limits the ability to predict and prevent preterm delivery in the most high-risk populations.

The Effects Of Diabetes Self-Management Education Among African Americans, Nkeiruka Muonagolu, Joyce Knestrick, Karen Kesten

GW Research Showcase 2021-2024

No abstract provided.

Illuminating Health Disparities: The Untold Story Of Black Women’S Pregnancies, Kacy Workman

Osmosis Magazine

Recent studies have found that Black women are 3-4 times more likely to die from pregnancy-related complications than White women. Researchers in the 1990s examined data surrounding specific pregnancy complications such as postpartum hemorrhage, finding that although prevalence rates were similar between White and Black women, Black women with these conditions were 2-3 times more likely to die than their White counterparts. Despite medical advances, these rates have not improved over time. Data analyses examining maternal mortality from 2005 – 2014 reveal that mortality rates for Black women have actually increased from 39 to 49 deaths for every 100,000 live …

Neurological Complications Of Covid19 During March 2020 At Lcmc Health University Medical Center: Dataset, David Chachkhiani, Michael Y. Soliman, Delphi Barua, Marine Isakadze, Nicole R. Villemarette-Pittman, Deidre J. Devier, Jesus F. Lovera

School of Medicine Faculty Publications

We reviewed the electronic medical records (EMR) of patients hospitalized during the peak of the pandemic, March 1st through March 31st, to document the type and frequency of neurological problems seen in patients with COVID-19 at presentation to the emergency room. Secondary aims were to determine: 1) the frequency of neurological complaints during the hospital stay; 2) whether the presence of any neurological complaint at presentation or any of the individual types of neurological complaints at admission predicted three separate outcomes: death, length of hospital stay, or the need for intubation; and 3) if the presence of any neurological complaint …

Whole-Genome Sequencing Of African Americans Implicates Differential Genetic Architecture In Inflammatory Bowel Disease, Hari K Somineni, Rodney D Newberry, Et Al.

2020-Current year OA Pubs

Whether or not populations diverge with respect to the genetic contribution to risk of specific complex diseases is relevant to understanding the evolution of susceptibility and origins of health disparities. Here, we describe a large-scale whole-genome sequencing study of inflammatory bowel disease encompassing 1,774 affected individuals and 1,644 healthy control Americans with African ancestry (African Americans). Although no new loci for inflammatory bowel disease are discovered at genome-wide significance levels, we identify numerous instances of differential effect sizes in combination with divergent allele frequencies. For example, the major effect at PTGER4 fine maps to a single credible interval of 22 …

Understanding African Americans' Beliefs, Knowledge, Attitudes And Behaviors Regarding High Blood Pressure And Their Use Of Home Remedies As Treatment, Elisa Douglas

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

Understanding African Americans’ Beliefs, Knowledge, Attitudes and Behaviors Regarding High Blood Pressure and Their Use of Home Remedies as Treatment

Elisa E. Douglas

Seton Hall University, 2021

Dissertation Chair: Dr. Deborah DeLuca, J.D., MS

Background and Purpose of the Study: African Americans have the highest prevalence of high blood pressure (HBP) in the United States but the lowest blood pressure (BP) control rates of any major race/ ethnic group. Only about 45% of those who use drugs to treat the condition have been able to attain BP control. Over 40% of African Americans are affected by HBP. African Americans …

Whole-Exome Sequencing And Hipsc Cardiomyocyte Models Identify Myrip, Trappc11, And Slc27a6 Of Potential Importance To Left Ventricular Hypertrophy In An African Ancestry Population, Marguerite R. Irvin, Praful Aggarwal, Steven A. Claas, Lisa De Las Fuentes, Anh N. Do, C. Charles Gu, Andrea Matter, Benjamin S. Olson, Amit Patki, Karen Schwander, Joshua D. Smith, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amy J. Turner, Deborah A. Nickerson, Dabeeru C. Rao, Ulrich Broeckel, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Background: Indices of left ventricular (LV) structure and geometry represent useful intermediate phenotypes related to LV hypertrophy (LVH), a predictor of cardiovascular (CV) disease (CVD) outcomes.

Methods and Results: We conducted an exome-wide association study of LV mass (LVM) adjusted to height^2.7, LV internal diastolic dimension (LVIDD), and relative wall thickness (RWT) among 1,364 participants of African ancestry (AAs) in the Hypertension Genetic Epidemiology Network (HyperGEN). Both single-variant and gene-based sequence kernel association tests were performed to examine whether common and rare coding variants contribute to variation in echocardiographic traits in AAs. We then used a data-driven …

Risk Factors Associated With Opioid Use Among African American Faith-Based Populations, Kelsey Christensen Ma, Jannette Berkley-Patton Phd, Alexandria Bauer Phd, Carole Bowe Thompson, Tacia Burgin

Journal of Health Disparities Research and Practice

African Americans (AAs) in the Midwest are more likely to die from an opioid overdose compared to Whites, despite lower rates of use. Little is known about factors related to opioid use among AAs residing in the Midwest, particularly church-affiliated AAs. AAs have the highest rate of church attendance among all racial/ethnic groups, and the Black Church may be an appropriate setting for prevention efforts. The present study sought to better understand factors related to opioid use among Midwestern church-affiliated AAs to inform future faith-based interventions. This study examined predictors of opioid use (ever) using survey data from Taking It …

The Intersection Of Rural Residence And Minority Race/Ethnicity In Cancer Disparities In The United States, Whitney Zahnd, Cathryn Murphy, Marie Knoll, Gabriel A. Benavidez, Kelsey R. Day, Radhika Ranganathan, Parthenia Luke, Anja Zgodic, Kewei Shi, Melinda A. Merrell, Elizabeth L. Crouch, Heather M. Brandt, Jan Eberth

Faculty Publications

One in every twenty-five persons in America is a racial/ethnic minority who lives in a rural area. Our objective was to summarize how racism and, subsequently, the social determinants of health disproportionately affect rural racial/ethnic minority populations, provide a review of the cancer disparities experienced by rural racial/ethnic minority groups, and recommend policy, research, and intervention approaches to reduce these disparities. We found that rural Black and American Indian/Alaska Native populations experience greater poverty and lack of access to care, which expose them to greater risk of developing cancer and experiencing poorer cancer outcomes in treatment and ultimately survival. There …

Disparities In Sars-Cov-2 Positivity Rates: Associations With Race And Ethnicity, Harvey W Kaufman, Justin K Niles, David B. Nash

College of Population Health Faculty Papers

Numerous reports indicate that African Americans and Latinos are being affected disproportionately by coronavirus disease 2019 (COVID-19). Positivity rates have not been analyzed on scale because only 4 states report race/ethnicity as part of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. Previous studies also have had little ability to control for many known risk factors to better identify the effects of COVID-19 on racial and ethnic communities. Using test results from a large national reference laboratory database that included patients from all 50 states and the District of Columbia, this study compared positivity rates for SARS-CoV-2 nucleic acid amplification …

Critical Importance Of Using Fibroscan To Identify Patients With Cirrhosis In A Predominantly African American Patient Population, Sarah Nasser, Katherine Wong, Paul Naylor, Murray Ehrinpreis, Milton Mutchnick

Medical Student Research Symposium

Introduction: Identifying patients with cirrhosis is complicated, but the availability of Transient Elastography by FibroScan for non-invasive assessment of fibrosis appears to have resolved this issue. The objective of our study was to use a Fibroscan database to identify patients with cirrhosis in our primarily African American Hepatitis C patients and to track outcome especially of patients with Hepatitis C (HCV).

Methods: The electronic medical records of 79 out of the 332 individuals (24%) with a Fibroscan between 2014 and 2016 and a score of >12.5 kPa laboratory values recorded, and etiology and outcomes evaluated. AST to Platelet …

Healthcare Access For Elderly African American Type 2 Diabetics On Medicare, William Alexander Floyd

Walden Dissertations and Doctoral Studies

AbstractPrior research has shown that African Americans have less access to healthcare than do White Americans. The study’s purpose was to determine the association between race/ethnicity and quality care measures in a population of Medicare recipients with Type 2 diabetes, aged 65 75 years and over. Covariates predicted satisfaction with doctor care, compassionate doctor care, and indifferent doctor care using Andersen’s health behavior theory. The Medicare Current Beneficiary Survey (MCBS) sample consisted of 1,716 people with Type 2 diabetes, with most (76.6%) being non-Hispanic Whites, and the remainder non-Hispanic Blacks (10.8%) and Hispanics (12.6%). Race/ethnicity were associated with quality-of-care measures …

Improving Nurses’ Knowledge To Provide Diabetes Self-Management Education For African Americans, Jakeyla Reed

Walden Dissertations and Doctoral Studies

African Americans are at high risk for type II diabetes compared to other ethnic groups due to biological, socioeconomic, and psychosocial risks. Specifically, African American adults are nearly two times more likely than White individuals to develop type II diabetes. The meaningful gap-in-practice addressed by this doctoral project was nurses’ lack of diabetes knowledge affecting their ability to provide diabetes care and diabetes self-management education (DSME) to their patients with diabetes. The clinical practice-focused question asked whether an education intervention for outpatient clinic nurses could improve their knowledge of DSME. Orem’s self-care model, Bandura’s self-efficacy theory, and Lewin’s change theory …

Increasing Nurse Knowledge Of The Underutilization Of Hospice Services For African Americans, Vicki Schmidt

Walden Dissertations and Doctoral Studies

The focus of this doctoral project was increasing knowledge of underutilization ofhospice services for African Americans (AAs) and the need to increase cultural competence among nurses regarding this issue. The identified gap in practice was nurses’ lack of cultural competence and knowledge regarding the underutilization of hospice specific to AAs. The practice-focused question focused on whether a staff educational intervention increased nurses’ knowledge of the cultural implications regarding the introduction of hospice services for AAs. The education was guided by the Purnell model for culturally competent health care, Healthy People 2030, and the National Hospice and Palliative Care Organizations AA …

The Effect Of Lifestyle Modification Educational Intervention On Increasing Knowledge Of Hypertension Management Among African American Adults, Margaret Josiah

Graduate Research Showcase

Abstract

Hypertension is a public health crisis that disproportionately affects the African American population more than other races (CDC, 2019). There is a direct link between hypertension and an increased risk for cardiovascular disease in the United States (CDC, 2019). Though tremendous efforts have been made in the treatment and management of hypertension, it continues to be a challenge worldwide. African Americans that receive only pharmacological therapy have not shown significant control over hypertension (Kimani, 2019). Therefore, to improve the health outcomes in the African American community, a systematic comprehensive approach that includes lifestyle modification and medication adherence is crucial. …

Addressing Medical Mistrust In In-Patient Psychiatric African American (Aa) Patients, Eselle Molua

DNP Scholarly Projects

Abstract

Background: Medical Mistrust (MM) is associated with patient dissatisfaction, treatment nonadherence, and poor health outcomes. In the United States, MM is prevalent in African American patients in In-Patient Psychiatric settings. Caregiver training and education on MM and cultural sensitivity can help identify mistrust and provide strategies to increase trust and reduce mistrust.

Purpose: The aim of this project was to implement an educational tool to improve caregiver awareness about knowledge of MM. By doing so, it was the goal to enhance cultural sensitivity skills and patient-centeredness in the African American population at the adult psychiatric unit in Northwest …

Internet Use, Perceived Social Support, And Obesity Among African American Young Adults, Cynthia Adams

Walden Dissertations and Doctoral Studies

African Americans are disproportionately affected by obesity. Public health practitioners have an incomplete understanding of the social-environmental risk factors and how they affect obesity. The purpose of this quantitative, cross-sectional study was to explore whether internet use and perceived social support predicted obesity among African American young adults. The social cognitive theory guided this study. Secondary data were analyzed from the 2017 Behavioral Risk Factor Surveillance Survey. The sample consisted of 6,765 African American young adults age 18 to 34 and represented the U.S. population using weighted estimates. A Bonferroni correction was performed to reduce Type I error due to …