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Comparative Analysis Of Proteomics Biomarkers Associated With Residual Ridge Resorption Induced By Denture Wear, Rohana Ahmad, Ainin Sofia Mohamad Napi, Tong Wah Lim, Su Keng Tan, Saiful Anuar Karsani, Musalmah Mazlan, Lay Kek Teh, Steven M. Morgano, Nadim Z. Baba

Makara Journal of Health Research

Background: The biochemical bone turnover markers for residual ridge resorption (RRR) are unclear. Therefore, the present study aimed to determine the biochemical bone turnover markers associated with RRR by comparing proteomics between the compressed mucosa of denture wearers and the non-compressed mucosa of non-denture wearers.

Methods: The mucosal specimens of 11 complete-denture wearers were obtained from the alveolar ridge during surgical implant exposure for implant-retained overdentures. All denture wearers had been edentulous and worn dentures for at least 5 years. The tissues of 11 non-denture wearers were taken from the ridge during minor preprosthetic surgery. The mucosal proteins …

Investigations On Congenital And Induced Osteopetrosis, Donald G. Walker

MCV/Q, Medical College of Virginia Quarterly

Osteopetrosis, or marble bone disease, is a disturbance of skeletal development in which the rate of bone resorption fails to keep pace with the rate of bone formation. Bone matrix accumulates excessively throughout the skeletal system, causing damage to neighboring tissues--particularly the dental, hematopoietic and nervous tissues. The line of investigation on osteopetrosis which has led to the current point of view that the thyroid gland represents the primary side of the disturbance was initiated soon after an experimental animal became available.