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Characterization Of The Effect Of Serum And Chelating Agents On Staphylococcus Aureus Biofilm Formation; Chelating Agents Augment Biofilm Formation Through Clumping Factor B, Nabil Mathew Abraham

Theses and Dissertations

Staphylococcus aureus is the causative agent of a diverse array of acute and chronic infections, and some these infections, including infective endocarditis, joint infections, and medical device-associated bloodstream infections, depend upon its capacity to form tenacious biofilms on surfaces. Inserted medical devices such as intravenous catheters, pacemakers, and artificial heart valves save lives, but unfortunately, they can also serve as a substrate on which S. aureus can form a biofilm, attributing S. aureus as a leading cause of medical device-related infections. The major aim of this work was take compounds to which S. aureus would be exposed during infection and …