Digital Commons Network^™

Gender Differences In Dementia Management Plans Of Spousal Caregivers: Implications For Occupational Therapy., Mary A. Corcoran

Department of Occupational Therapy Faculty Papers

Occupational therapists treating older people with Alzheimer disease know that they must also consider the others who are affected by the disease, the informal caregivers. Intervention is most effective when it enables both the impaired person and the primary caregiver to manage the secondary symptoms of dementia. Unfortunately, little is understood about how caregivers approach and carry out their tasks and about why male and female caregivers respond differently to their caregiving role in terms of depression, burden, stress, and substance abuse. This paper discusses the effects of gender on dementia management plans of spousal caregivers. Husbands and wives have …

Childhood Typhoid Fever Diagnosed In An Urban U.S. Setting., Surinder K. Sodhi, Stephen C. Eppes, Joel D. Klein

Department of Pediatrics Faculty Papers

The majority of cases of childhood typhoid fever diagnosed in the United States occur in persons recently returned from travel abroad. We report two childhood cases of typhoid fever acquired in Mexico and India and diagnosed in an urban United States setting. This report describes these cases and provides insights into the pitfalls in recognizing this condition in a nonendemic setting as well as information concerning differential diagnosis and treatment.

Jefferson Alumni Bulletin – Volume Xlii, Number 1, Fall 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 1, Fall 1992

New challenges are met successfully, page 2

The longitudinal study, page 4

Changes strengthen curriculum, page 6

Applications reach all-time high, page 7

The critical link between clinical practice and basic science, page 8

Drive to raise $200 million is in high gear, page 12

Hamilton professors are named, page 13

New Rorer professor, page 14

Endocrinology director appointed, page 14

Bequest from dubbs, ’31 establishes fellowships, page 15

New associate Dean, page 15

$5 million grant made to Jefferson cancer institute, page 16

President Brucker is welcomed in Washington, …

Dementia Management: An Occupational Therapy Home-Based Intervention For Caregivers., Mary A. Corcoran, Laura N. Gitlin

Department of Occupational Therapy Faculty Papers

This paper describes an occupational therapy intervention designed for family caregivers of persons with dementia. The intervention, based on the framework of a competence-environmental press model and the principle of collaboration, was implemented during 5 home visits. Each visit was designed to build caregiving skills through collaboration in identifying problem areas, developing and implementing environmental strategies, and modifying management approaches. A case vignette illustrates the therapeutic process and outcomes. The theoretical rationale and structure of the intervention and innovative documentation for evaluation of the theoretic process are also presented.

Antibodies Against Epstein-Barr Nuclear Antigen (Ebna) In Multiple Sclerosis Csf, And Two Pentapeptide Sequence Identities Between Ebna And Myelin Basic Protein., Patrick F. Bray, J Luka, Paul F. Bray, K W. Culp, J P. Schlight

Cardeza Foundation for Hematologic Research

The Epstein-Barr virus (EBV) causes infectious mononucleosis and is linked to several disparate malignancies. Prior studies on patients with multiple sclerosis (MS) showed that 100% are EBV-seropositive and that their blood contains higher antibody titers than those of controls to both transformation and lytic cycle antigens. We performed three different assays for antibodies in CSF to three major EBV antigens from patients with MS and controls. Among 93 patients with MS, 79 (85%) had CSF that reacted with a 70 kD protein, shown to be the nuclear antigen, EBNA-1, whereas only 11 (13%) of 81 EBV-seropositive controls reacted, p less …

Jefferson Alumni Bulletin – Volume Xli, Number 4, Summer 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 4, Summer 1992

Malignant bone tumors developing at sites of benign preexisting bone disease, page 13

An experience with a small rural hospital, page 15

The prevention of Turista and the enjoyment of foreign travel, page 16

The Nemours children’s clinic, page 17

The shoulder revisited, page 19

Jeff’s trauma program, page 20

The biochemical basis for diabetic nephropathy, page 21

Dealing with the media, page 23

Space motion sickness, page 24

Total joint replacement, page 25

Decision making and the doctor-patient relationship, 26

New endowed chair, page 30

Inaugural grandon lecture, page …

Department Of Radiology-Annual Report-July 1, 1991 To June 30, 1992, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1991 to June 30, 1992. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 72 pages.

Insulin Receptor And Epidermal Growth Factor Receptor Dephosphorylation By Three Major Rat Liver Protein-Tyrosine Phosphatases Expressed In A Recombinant Bacterial System, Naotake Hashimoto, Wei-Ren Zhang, Barry J. Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine phosphatases (PTPases) play an essential role in the regulation of signal transduction mediated by reversible protein-tyrosine phosphorylation. In order to characterize individual rat hepatic PTPases that might have specificity for autophosphorylated receptor tyrosine kinases, we isolated cDNA segments encoding three PTPases (PTPase 1B, LAR and LRP) that are expressed in insulin-sensitive liver and skeletal muscle tissue, and evaluated their catalytic activity in vitro. The intrinsic PTPase activities of the full-length PTPase 1B protein and the cytoplasmic domains of LAR and LRP were studied by expression of recombinant cDNA constructs in the inducible bacterial vector pKK233-2 using extracts of …

Alternative Splicing Of Human Prostaglandin G/H Synthase Mrna And Evidence Of Differential Regulation Of The Resulting Transcripts By Transforming Growth Factor Beta 1, Interleukin 1 Beta, And Tumor Necrosis Factor Alpha., Arturo Diaz, Anthony M. Reginato, Sergio A. Jimenez

Department of Medicine Faculty Papers

Prostaglandin G/H synthase (PGG/HS) is the rate-limiting enzyme in the conversion of arachidonic acid to prostaglandins and thromboxanes. We screened a human lung fibroblast cDNA library with an ovine PGG/HS cDNA and isolated a 2.3-kilobase clone (HCO-T9). Sequence analysis of this clone showed that (a) it contained the entire translated region of PGG/HS and (b) it displayed an in-frame splicing of the last 111 base pairs encoded by exon 9, which resulted in the elimination of the N-glycosylation site at residue 409. Polymerase chain reaction amplification with specific oligonucleotides of reverse-transcribed mRNA from diverse human tissues and cultured cells yielded …

Jefferson Alumni Bulletin – Volume Xli, Number 3, Spring 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 3, Spring 1992

State of the division 1992, page 2

Interviews with two distinguished faculty members, page 5

Programs link Alumni and students, page 9

Robert Gallo, ’63 and the human element, page 10

On campus, page 14

Drawing on his medical knowledge, page 17

American psychiatric association chooses Joseph T. English, ’58 as president, page 19

Class notes, page 24

Jefferson Alumni Bulletin – Volume Xli, Number 2, Winter 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 2, Winter 1992

The Medical Scholars Program, page 2

Jefferson and Cancer Research, page 6

The Cardeza Foundation for Hematologic Research, page 9

The Contribution of Frederick Roscher to Jefferson's Art Collection, page 14

Multidisciplinary Research and a Broader Teaching of Outpatient Medicine Are Planned by the New Chairman of Medicine, page 17

On Campus, page 18

Class Notes, page 23

Germbuster Brainteaser: A Novel Education Tool, Andrew Sirotnak, Md, Joel D. Klein, Md, Stephen C. Eppes, Md

Department of Pediatrics Faculty Papers

As part of the Pediatric Infectious Diseases elective at the Alfred I. duPont Institute, pediatric residents from the Medical Center of Delaware and the Thomas Jefferson Medical College are encouraged to contribute original, educational material to our Germbusters newsletters. We thought readers of the Delaware Medical Journal would enjoy seeing one of the more innovative resident contributions.