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Effects Of Melatonin On Heartbeat And Possible Identification Of A Melatonin Receptor In Drosophila Melanogaster, Tricia L. Vankirk Dec 2015

Effects Of Melatonin On Heartbeat And Possible Identification Of A Melatonin Receptor In Drosophila Melanogaster, Tricia L. Vankirk

Electronic Theses and Dissertations

Chapter 1 of this manuscript is a literature review that serves as an introduction to the entire dissertation. Chapter 2 examines the effects of the melatonin injection on heart rate and rhythmicity in Drosophila melanogaster Canton-S (wild-type) pupae and pupae bearing a variety of heart mutations. Chapter 3 investigates further the possible mechanisms of melatonin’s ability to increase heart rhythmicity without significantly affecting heart rate. A melatonin antagonist, luzindole; a high-affinity melatonin agonist, 2-iodomelatonin and RNAi techniques are used to identify a possible melatonin receptor in Drosophila melanogaster.

An appendix contains a previously published manuscript detailing experiments performed at the …


Physical Activity Levels And Health Of Passamaquoddy Tribe At Indian Township, Michael R. Best Nov 2015

Physical Activity Levels And Health Of Passamaquoddy Tribe At Indian Township, Michael R. Best

Electronic Theses and Dissertations

This study focuses on reporting the occupational, household, transportation and leisure time physical activity of the Passamaquoddy Tribe at Indian Township. This study also focuses on health measures and the presence of chronic disease and how they are affected by physical activity, risk factors, and other health related measures.

An interview-administered questionnaire, developed by the CDC, was given to participants age 25-44 years old, with one small change. The original Intertribal Heart Project (ITHP) questionnaire used a shortened version of the WHO’s Monica Optional Study of Physical Activity (MOSPA), in order to reduce the time it takes to administer the …