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Medicine and Health Sciences

The Texas Medical Center Library

2008

Adult

Articles 1 - 2 of 2

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The Performance Of Human Papillomavirus High-Risk Dna Testing In The Screening And Diagnostic Settings, Marylou Cárdenas-Turanzas, Graciela M Nogueras-Gonzalez, Michael E Scheurer, Karen Adler-Storthz, J L Benedet, J Robert Beck, Michele Follen, Scott B Cantor Oct 2008

The Performance Of Human Papillomavirus High-Risk Dna Testing In The Screening And Diagnostic Settings, Marylou Cárdenas-Turanzas, Graciela M Nogueras-Gonzalez, Michael E Scheurer, Karen Adler-Storthz, J L Benedet, J Robert Beck, Michele Follen, Scott B Cantor

Journal Articles

OBJECTIVE: We sought to evaluate the performance of the human papillomavirus high-risk DNA test in patients 30 years and older.

MATERIALS AND METHODS: Screening (n=835) and diagnosis (n=518) groups were defined based on prior Papanicolaou smear results as part of a clinical trial for cervical cancer detection. We compared the Hybrid Capture II (HCII) test result with the worst histologic report. We used cervical intraepithelial neoplasia (CIN) 2/3 or worse as the reference of disease. We calculated sensitivities, specificities, positive and negative likelihood ratios (LR+ and LR-), receiver operating characteristic (ROC) curves, and areas under the ROC curves for the …


Effect Of Progressive Mandibular Advancement On Pharyngeal Airway Size In Anesthetized Adults., Samuel T Kuna, Lee C Woodson, Daneshvari R Solanki, Oliver Esch, Donald E Frantz, Mali Mathru Oct 2008

Effect Of Progressive Mandibular Advancement On Pharyngeal Airway Size In Anesthetized Adults., Samuel T Kuna, Lee C Woodson, Daneshvari R Solanki, Oliver Esch, Donald E Frantz, Mali Mathru

Journal Articles

BACKGROUND: General anesthesia in adult humans is associated with narrowing or complete closure of the pharyngeal airway. The purpose of this study was to determine the effect of progressive mandibular advancement on pharyngeal airway size in normal adults during intravenous infusion of propofol for anesthesia.

METHODS: Magnetic resonance imaging was performed in nine normal adults during wakefulness and during propofol anesthesia. A commercially available intraoral appliance was used to manually advance the mandible. Images were obtained during wakefulness without the appliance and during anesthesia with the participants wearing the appliance under three conditions: without mandibular advancement, advancement to 50% maximum …