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Rearrangement Of The Bcl-6 Gene As A Prognostic Marker In Diffuse Large-Cell Lymphoma, K. Offit, D.C. Louie, N. Z. Parsa, Denis H. Y. Leung, C. Portlock, B.H. Ye, F. Lista, D.A. Filippa, A. Rosenbaum, M. Ladanyi, S. Jhanwar, R. Dalla-Favera, R.S.K. Changanti
Rearrangement Of The Bcl-6 Gene As A Prognostic Marker In Diffuse Large-Cell Lymphoma, K. Offit, D.C. Louie, N. Z. Parsa, Denis H. Y. Leung, C. Portlock, B.H. Ye, F. Lista, D.A. Filippa, A. Rosenbaum, M. Ladanyi, S. Jhanwar, R. Dalla-Favera, R.S.K. Changanti
Research Collection School Of Economics
Current therapy can induce a long-term remission in half the patients with diffuse lymphomas with a large-cell component (DLLC), but more intensive treatment has the potential to improve outcome. Rearrangement of a novel candidate proto-oncogene, bcl-6, correlates with a favorable clinical outcome in DLLC and may thus serve as a prognostic marker.