Digital Commons Network^™

Does Dupilumab Decrease The Amount Of Asthma Exacerbations In Patients Suffering From Asthma Compared To Placebo?, Rachel N. Campo

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic EBM review is to determine “Does dupilumab decrease the amount of asthma exacerbations in patients suffering from asthma compared to placebo?”

STUDY DESIGN: A review of three randomized, placebo-controlled trials (RCTs) that were peer reviewed and published in English after 2009.

DATA SOURCE: All articles were published in peer reviewed journals and were researched using PubMed. Studies were selected based on their ability to answer the question posed in the objective, and if the researched outcomes were patient oriented.

OUTCOMES: Assessed outcomes were either the occurrence or rate of asthma exacerbations during the studies. …

Does Aerobic Training On A Treadmill Improve Symptomatic Control And Quality Of Life In Patients With Asthma?, Brianna Bracy

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Does aerobic training on a treadmill improve symptomatic control and quality of life in patients with asthma?”

STUDY DESIGN: This is a systematic review of three randomized control trials (RCTs) published between 2013 and 2016 in peer-reviewed journals.

DATA SOURCES: Three randomized control trials (RCTs) were found using PubMed. All articles were published in peer reviewed journals and selected based on their relevance to the topic and evaluation of outcomes that mattered to patients.

OUTCOMES MEASURED: Symptomatic control was measured by recording occurrence of symptoms in …

Understanding The Comorbidity Of Asthma And Anxiety In Childhood: Characteristics, Vulnerabilities, And Treatment Implications, Nicole Fleischer, Elizabeth Gosch, Phil Kendall

Research Day

Introduction: Given the high incidence of asthma and anxiety comorbidity, clinicians should be informed of the unique presentation of these clients in clinical practice. Although much is known about the development and characteristics of childhood anxiety, less is known about children with anxiety and comorbid asthma.

Methods: This study, using archival data, examined the potential differences in children with comorbid asthma and anxiety compared to children with anxiety from a random controlled trial. These two groups were compared on negative self-talk, number of physical symptoms, parent anxiety, content of their worries, and presence of panic, generalized anxiety, and …

Is Reslizumab Effective In Improving Quality Of Life And Asthma Control In Adolescent And Adult Patients With Poorly Controlled Eosinophilic Asthma?, Carrie A. Notestine

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not reslizumab is effective in improving quality of life and asthma control in adolescent and adult patients with poorly controlled eosinophilic asthma.

STUDY DESIGN: This is a systematic review of three randomized controlled trials, published in peer-reviewed journals from 2015 and 2016.

DATA SOURCES: Three randomized, placebo-controlled, double-blind clinical trials comparing the effectiveness of reslizumab to a placebo in improving quality of life and asthma control. Articles were found using CINAL and PubMed databases.

OUTCOMES MEASURED: Outcomes measured include quality of life, assessed using the Asthma Quality …

Is The Addition Of Vitamin D In Treatment For Asthma Effective In Children Less Than 18 Years Old?, Danielle M. Read

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the addition of vitamin D in treatment for asthma is effective in children less than 18 years old.

STUDY DESIGN: Review of three English language, randomized, controlled, double blind studies after 1999.

DATA SOURCES: Randomized, controlled double blind studies comparing the addition of vitamin D with an inhaled corticosteroid in treatment of asthma with a control group of inhaled corticosteroid alone. All articles were found in PubMed.

OUTCOMES MEASURED: Each study assessed the number of asthma exacerbations or symptoms in the control group and in the …

Are Probiotics Effective At Reducing The Symptoms Of Asthma In Children From Birth To Twelve-Years Old?, Rachel Sulat

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not probiotics are effective at reducing the symptoms of asthma in children ages birth to twelve-years old.

STUDY DESIGN: Review of three English-language, double-blinded randomized controlled trials (RCTs) from 2010 and 2011.

DATA SOURCES: Three peer-reviewed RCTs were found using PubMed database. These studies compared probiotics to placebos in patients with episodes of wheezing.

OUTCOMES MEASURED: Reduction in symptoms of asthma (particularly wheezing) measured with the use of diary cards and symptom scores.

RESULTS: Chen et al. demonstrated statistically significant improvement in daytime asthma symptoms in probiotic treated …

Is Oral Dexamethasone Safe And Effective For Treating Asthma Exacerbations In Pediatric Patients?, Benhamin J. Kunze

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence based medicine review is to determine whether or not a one or two dose regimen of dexamethasone (DEX) is a safe and effective treatment for asthma exacerbations in the pediatric population.

STUDY DESIGN: Review of three English language, primary randomized controlled trials (RCT) published from 2001-2008.

DATA SOURCES: Three RCTs examining the efficacy of DEX either in a single dose or one dose for two days, compared to a traditional five day regimen of prednisone (PRED).

OUTCOMES MEASURED: The studies examined the number of relapses within 10 days of …

Does The Use Of Fascial Manipulative Therapy Help To Improve Overall Asthma Quality Of Life By Descreasing Asthma Symptoms?, Christie Mecouch

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of fascial manipulative therapy helps to improve overall asthma quality of life by decreasing asthma symptoms.

STUDY DESIGN: Review of two randomized controlled trials (RCTs) and one case study, published between 2005-current, all in the English language.

DATA SOURCES: Two randomized controlled trials (RCTs) and one case study, all of which evaluate the effectiveness of fascial manipulative therapy as it pertains to asthma quality of life. All studies were found using PubMed.

OUTCOMES MEASURED: The outcomes measured were an improvement …

Asthma & Cardiac Physician Treatment (Techniques), Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Dr Koch's notes on treatment techniques used for his patients with asthma/cardiac issues.

Personal Notes On Asthma And Colds, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Dr Koch's personal notes on asthma and colds.

Structural Patterns & Principles Of Treatment In Asthmatic Patients, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Discusses and provides evidence for connection between spinal asymmetries and asthma.