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Nano-Hydroxyapatite And Nano-Hydroxyapatite/Zinc Oxide Scaffold For Bone Tissue Engineering Application, Fatemeh Heidari, Reza Bazargan-Lari, Mehdi Razavi, Farahnaz Fahimipour, Daryoosh Vashaee, Lobat Tayebi
Nano-Hydroxyapatite And Nano-Hydroxyapatite/Zinc Oxide Scaffold For Bone Tissue Engineering Application, Fatemeh Heidari, Reza Bazargan-Lari, Mehdi Razavi, Farahnaz Fahimipour, Daryoosh Vashaee, Lobat Tayebi
School of Dentistry Faculty Research and Publications
This research aims to evaluate the mechanical properties, biocompatibility, and degradation behavior of scaffolds made of pure hydroxyapatite (HA) and HA‐modified by ZnO for bone tissue engineering applications. HA and ZnO were developed using sol‐gel and precipitation methods respectively. The scaffolds properties were characterized using X‐ray diffraction (XRD), Fourier transform spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), atomic absorption (AA), and atomic force microscopy (AFM). The interaction of scaffold with cells was assessed using in vitro cell proliferation and alkaline phosphatase (ALP) assays. The obtained results indicate that the HA/ZnO scaffolds possess higher …
Porous Magnesium-Based Scaffolds For Tissue Engineering, Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee, Keyvan Moharamzadeh, Aldo R. Boccaccini, Lobat Tayebi
Porous Magnesium-Based Scaffolds For Tissue Engineering, Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee, Keyvan Moharamzadeh, Aldo R. Boccaccini, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Significant amount of research efforts have been dedicated to the development of scaffolds for tissue engineering. Although at present most of the studies are focused on non-load bearing scaffolds, many scaffolds have also been investigated for hard tissue repair. In particular, metallic scaffolds are being studied for hard tissue engineering due to their suitable mechanical properties. Several biocompatible metallic materials such as stainless steels, cobalt alloys, titanium alloys, tantalum, nitinol and magnesium alloys have been commonly employed as implants in orthopedic and dental treatments. They are often used to replace and regenerate the damaged bones or to provide structural support …