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Molecular Genetic Investigation Of Autosomal Dominant Hemifacial Microsomia, Rebecca Watt
Molecular Genetic Investigation Of Autosomal Dominant Hemifacial Microsomia, Rebecca Watt
Theses: Doctorates and Masters
The overall purpose of this project was to explore the underlying pathogenesis of Hemifacial microsomia (HFM), investigate treatment and management options identify likely candidate genes and screen candidate genes for mutation(s) causing the form of HFM segregating on chromosome 11 in a West Australian family. Hemifacial microsomia is a congenital malformation arising from the derivatives of the first and second branchial arches. It is both clinically and genetically heterogeneous and can occur sporadically or segregate within families in an autosomal fashion. HFM is characterised by significant undergrowth to one side of the face and is a common birth defect with …
Deep Muscle Function In The Cervical Spine: Application To Musculoskeletal Modelling, Jonathon Green
Deep Muscle Function In The Cervical Spine: Application To Musculoskeletal Modelling, Jonathon Green
Theses : Honours
Neck pain in occupational tasks is a problem that involves a high cost to society therefore, understanding the mechanics of musculoskeletal loading is important in formulating preventative rehabilitation strategies. Musculoskeletal modelling of the neck provides a means by which to calculate loads on the components and muscles of the neck thus allowing quantitative data to be gained non-invasivcly for a wide range of occupational tasks. Anatomically detailed, electromyography (EMG) driven neck models require deep muscle EMG activation profiles which arc difficult to attain without invasive EMG procedures. The aim of this study was to determine whether EMG activity of semispinalis …