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Perturbations Of Periosteel Bone During Healing: Effect Of Non-Weight Bearing, Helen E. Gruber, Mary E. Kirchen, John R. Sweeney, William E. Anderson, G. June Marshall
Perturbations Of Periosteel Bone During Healing: Effect Of Non-Weight Bearing, Helen E. Gruber, Mary E. Kirchen, John R. Sweeney, William E. Anderson, G. June Marshall
Cells and Materials
Weight bearing (WB) is an important factor influencing bone remodelling. The present study evaluates the effects of weight bearing and non-weight bearing (S) (achieved by tail suspension and hindlimb elevation) on the healing of a fibular osteotomy in adult male rats. After 9, 18 or 36 days under WB or S conditions, periosteum near the callus formed at the osteotomy site was compared to periosteum of the contralateral fibula (which did not receive an osteotomy) or to periosteum of fibula of control animals which did not receive an osteotomy. Data show that periosteal bone healing is sensitive to alterations in …