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Effect Of Modified Starch On Bake-Only Chicken Nuggets, Sarah Purcell Dec 2013

Effect Of Modified Starch On Bake-Only Chicken Nuggets, Sarah Purcell

Graduate Theses and Dissertations

The food industry has become increasingly focused on healthier items. Fried foods especially are actively pursuing non-fried alternatives to attract health conscience consumers. This study investigated the bake-only chicken nugget formulation in attempts to provide characteristics of fried items. Starch was hydrolyzed by amyloglucosidase to create a porous structure that had the ability to absorb oil. Oil was plated into the enzyme-treated starch and blended into nugget formulation, and the coated nuggets were steam-baked until fully cooked. The enzyme-treated starches showed a decrease in gelatinization range and pasting viscosities for all starch types. The addition of oil-plated enzyme modified starch …


The Effect Of Calcium And Nonphytate Phosphorus On Chicken Genetic Line, Egg Production, Shell Quality, Bone Homeostasis, And Progeny Bone Quality, Phiphob Sodsee Dec 2013

The Effect Of Calcium And Nonphytate Phosphorus On Chicken Genetic Line, Egg Production, Shell Quality, Bone Homeostasis, And Progeny Bone Quality, Phiphob Sodsee

Graduate Theses and Dissertations

The study consisted of two parts to determine effects of dietary calcium (Ca) and nonphytate phosphorus (NPP) level on four pure genetic lines of broiler breeders. The first part was concentrated on body composition, egg production and shell quality changes according to diet and genetic line. The second part was the study of bone homeostasis variables combining hematology, bone histology and body composition changes according to diet and genetic line. In the study, pullets (246 from each of pure genetic line A, B, C and D) were individually caged and light stimulated at 21 weeks of age. The study duration …


The Effects Of Salinity On Pythium Disease Of Rice And Soybean, Terea Jeanette Stetina Dec 2013

The Effects Of Salinity On Pythium Disease Of Rice And Soybean, Terea Jeanette Stetina

Graduate Theses and Dissertations

Increasing salinity is an important factor limiting agricultural productivity worldwide. In addition to direct effects on growth and yield, diseases also may be affected. This study characterized the effects of soil salinity on seedling disease of soybean and rice caused by Pythium spp. Controlled environment experiments on soybean used two cultivars which differed in chloride tolerance and soil treated with a CaCl2 solution to create a range of electrical conductivity (EC) levels. For soybean, soil was either not infested or infested with Pythium sylvaticum or P. aphanidermatum (pathogenic to soybean), or P. oligandrum (not pathogenic to soybean). Twenty-one days …


Evaluation Of Shake Weight Protocol In Senior Populations, Isaac F. Cook Dec 2013

Evaluation Of Shake Weight Protocol In Senior Populations, Isaac F. Cook

Graduate Theses and Dissertations

The Shake Weight® (SW®) is designed to improve muscular fitness in a quick and inexpensive way. This study aimed to determine if the SW® was an effective tool at improving muscular fitness, body composition, and bone mineral density (BMD) in post-menopausal women. Participants were 17 healthy, post-menopausal women from aMidwestern University and divided into two training (SW® and HIT) interventions that lasted 10 weeks. HIT participants performed three sets of 8 repetitions at 80% of their estimated 1RM for the chest press, leg press, lat pulldown, and seated row. SW® participants performed the exercises prescribed by the SW® manufacturer. Changes …


Molecular And Biochemical Mechanisms Of Pathogenesis In The Maize Foliar Pathogen Cercospora Zeae-Maydis, Winfred-Peck Dorleku Dec 2013

Molecular And Biochemical Mechanisms Of Pathogenesis In The Maize Foliar Pathogen Cercospora Zeae-Maydis, Winfred-Peck Dorleku

Graduate Theses and Dissertations

GLS is a serious foliar disease of maize, a major staple crop grown commercially in the USA for both human and animal feed production, and increasingly, for ethanol production. The disease is caused by two Cercospora species, C. zeae-maydis and C. zeina, both of which infect maize in the USA and in other parts of the world, with yield losses potentially greater than 50%, depending on local conditions. In culture, C. zeae-maydis produces a phytotoxic, host non-specific perylenequinone, cercosporin, and abscisic acid (ABA), for which there is no known pathological or physiological function in the fungus. Experimental evidence indicates …


Preservice Candidates' Rating Of Effectiveness In Agricultural Education Through Structured Communication With Cooperating Teachers, Christopher Lee Hunt Dec 2013

Preservice Candidates' Rating Of Effectiveness In Agricultural Education Through Structured Communication With Cooperating Teachers, Christopher Lee Hunt

Graduate Theses and Dissertations

The relationship between cooperating teacher and student has been found as one of the key elements that affect the overall teaching efficacy of student teachers and their decision to enter the teaching field after graduation (Edgar, 2007; Edgar, Roberts, & Murphy, 2011,2008; Kasperbauer et al., 2007a; Roberts, Greiman, Murphy, Ricketts, Harlin, & Briers 2009; Roberts, Harlin, & Briers, 2007, Roberts, Harlin, & Ricketts, 2006; Roberts Mowen, Edgar, Harlin & Briers, 2007, Stripling, Ricketts, Roberts & Harlin, 2008; Wolf, 2011; Wolf et al., 2010). Therefore, determining impacts towards teaching efficacy during the student teaching experience could play a vital role in …


Biochemical And Biophysical Studies Of Novel Features Of Ras-Related Protein Interactions, Kyla Marie Morinini Morris Dec 2013

Biochemical And Biophysical Studies Of Novel Features Of Ras-Related Protein Interactions, Kyla Marie Morinini Morris

Graduate Theses and Dissertations

The Ras superfamily of G-proteins are of great research interest for structure-function relationships among proteins as they act as molecular switches in the regulation of various biochemical reactions in the cell. They are regulated by protein-protein interactions targeted to the highly flexible switch regions. Mutations in G-proteins or their effectors may cause alterations in structure and/or function that can lead to overactivity.

The Ras-related protein Cell division cycle 42 (Cdc42) is important in regulating cell-signaling processes. The T35A mutation in Cdc42 leads to a decrease in flexibility of the Switch I region responsible for effector binding. The kinetics of the …


Bacterially-Mediated Formation Of Rock Coatings In Kärkevagge, Swedish Lapland: A Mineralogical And Micro-Environmental Analog For Mars, Cassandra L. Marnocha Dec 2013

Bacterially-Mediated Formation Of Rock Coatings In Kärkevagge, Swedish Lapland: A Mineralogical And Micro-Environmental Analog For Mars, Cassandra L. Marnocha

Graduate Theses and Dissertations

The search for past or present life on Mars is, for now, limited to surface environments. An often neglected surface environment that could have served as an abode for life and could presently preserve evidence of that life is that of rock coatings. Rock coatings are mineral accretions on rock surfaces. On Earth, they are widespread and occur with considerable chemical diversity. There is growing evidence for a biotic role in their formation on Earth, particularly with respect to rock varnish. As a result, rock varnish has become a target of astrobiological interest on Mars, where varnish-like coatings have been …


Effects Of Rain And Simulated Rain On Deoxynivalenol Levels In Grain And Chaff Of Winter Wheat With Fusarium Head Blight, Manoj Kumar Pun Dec 2013

Effects Of Rain And Simulated Rain On Deoxynivalenol Levels In Grain And Chaff Of Winter Wheat With Fusarium Head Blight, Manoj Kumar Pun

Graduate Theses and Dissertations

Wheat grain affected by Fusarium head blight (FHB) contains the mycotoxin deoxynivalenol (DON) that is harmful to humans and animals. Reducing the amount of DON in grain is the goal of management practices for FHB so it is important to understand the factors affecting DON in grain. Some studies on the effects of late-season moisture found increases in DON while others found decreases due to leaching. The objectives of this study were to determine effects of late-season rain and misting on DON concentration in wheat spike tissues and to quantify the amount of DON leached from spikes. Field experiments were …


Sugar And Rice Trade Between The United States And Cuba Trade Potential And Welfare Analysis, Fabian Bloechl Dec 2013

Sugar And Rice Trade Between The United States And Cuba Trade Potential And Welfare Analysis, Fabian Bloechl

Graduate Theses and Dissertations

After the resignation of President Fidel Castro and forty-five years of the U.S.-trade embargo, the political environment between Cuba and the United States is expected to change. With the Trade Sanction Reform and Export Enhancement Act in 2000, trade sanctions were eased for a while. Future trade between both countries would increase the welfare in both countries. This Thesis has the approach to look at the impacts on the commodities of rice and sugar, and the trade sanctions between the United States and Cuba.

Cuba is a net importer of its food supply; therefore, agriculture and food trade is an …


Effect Of Functional Starch In Brown Rice And Grain Sorghum On Plasma Glucose And Insulin Responses In Humans, Nicole Marie Poquette Dec 2013

Effect Of Functional Starch In Brown Rice And Grain Sorghum On Plasma Glucose And Insulin Responses In Humans, Nicole Marie Poquette

Graduate Theses and Dissertations

Diabetes and obesity are chronic illnesses increasing at dramatic rates in the U.S. and around the world. Research has looked to prevent or control diabetes and obesity through functional ingredients such as healthy-dietary carbohydrates to control blood glucose levels. Starch is a principle carbohydrate, which influences blood glucose levels, and measuring starch digestibility fractions can help predict the glucose response in the body. The objectives of this study were to investigate the functional starch content of parboiled brown rice flour and grain sorghum flour, and measure the effects on postprandial plasma glucose and insulin levels of 14 and 10 healthy …


Phenotypic, Physiological And Growth Interactions Among Salmonella Serovars, Juliany Rivera Calo Dec 2013

Phenotypic, Physiological And Growth Interactions Among Salmonella Serovars, Juliany Rivera Calo

Graduate Theses and Dissertations

This thesis consists of four research parts: a literature review that covers Salmonella spp., one of the more prominent foodborne pathogens that represents a major risk to humans (chapter 1). Understanding the growth of Salmonella serovars and strains is an important basis for more in depth research. In this case we studied a) the aerobic and anaerobic growth responses of multiple strains from six different serovars, b) how the spent media from different serovars, more importantly S. Heidelberg, affect the growth of S. Typhimurium, and c) determined whether or not two different serovars undergo competitive interactions when they were …


Long-Term Residue And Water Management Effects On Soil Respiration And Soil Aggregate Stability In A Wheat-Soybean, Double-Crop System In Eastern Arkansas, Sharon Faye Smith Dec 2013

Long-Term Residue And Water Management Effects On Soil Respiration And Soil Aggregate Stability In A Wheat-Soybean, Double-Crop System In Eastern Arkansas, Sharon Faye Smith

Graduate Theses and Dissertations

Sustainability in agriculture is paramount to assuring continued production from our most naturally fertile soils. Storing carbon (C) in soil as organic matter through sustainable agricultural management practices can both remove atmospheric C and improve soil quality. The objective of this study was to evaluate the long-term effects of water management (irrigation and dryland), residue management [burn and no-burn, conventional (CT) and no-tillage (NT)] and residue/fertility level (high and low) on soil respiration and aggregate stability in a wheat- (Triticum aestivum L.) soybean [Glycine max (L.) Merr.], double-crop system in a silt-loam soil (Aquic Fraglossudalf) in the Mississippi River Delta …


The Development Of An In Vivo Microdialysis Collection Method Of Cytokines From Brain Tissue, Anthony W. Herbaugh Dec 2013

The Development Of An In Vivo Microdialysis Collection Method Of Cytokines From Brain Tissue, Anthony W. Herbaugh

Graduate Theses and Dissertations

In this thesis, different methods to improve the microdialysis collection procedure for cytokines from brain tissue are presented. The first method was based on stopped flow and results indicating that no significant difference in relative recovery between stopped flow and continuous flow are shown. The second method is an antibody bead-based enhancement method. With the antibody bead-based method, a 3.5 fold increase in the collected concentrations of Chemokine (C-C motif) Ligand 2 (CCL2) were observed. However, there was no significant increase in the in vivo collection efficiency of Interleukin-6 (IL-6) using the antibody enhancement. Finally the development of an in-house …


In Vitro Analysis Of Short Chain Fatty Acids And Human Fecal Microbiota Stimulated By Pectin Sources, Byungjick Min Dec 2013

In Vitro Analysis Of Short Chain Fatty Acids And Human Fecal Microbiota Stimulated By Pectin Sources, Byungjick Min

Graduate Theses and Dissertations

As interest increases for colonic health, various studies have been conducted to investigate functional ingredients for host health and prevention of chronic disease in humans such as colon cancer and Type 2 diabetes. In particular dietary fiber has been reported to have beneficial effects on colonic health. More recently, dietary fiber has been categorized based on its characteristics and numerous studies have been conducted to determine correlations with chronic diseases. Pectin is a naturally occurring biopolymer that has been used in various applications for purposes of pharmaceutical and biotechnology. Pectin is a soluble dietary fiber and can be entirely fermented …


Effect Of Prescribed Burning In The Forests Of Buffalo National River, Arkansas, Francis Ndar Onduso Dec 2013

Effect Of Prescribed Burning In The Forests Of Buffalo National River, Arkansas, Francis Ndar Onduso

Graduate Theses and Dissertations

Prescribed burning (also referred to as controlled or hazard reduction burning) refers to the use of fire under controlled conditions to achieve a desired end product or goal. However, the nature and magnitude of the changes that result from prescribed burning are still incompletely known, and this is especially true for the forests of the Ozarks of northern Arkansas. The overall objective of the research project described herein was to obtain the data necessary to develop a better understanding of these changes, particularly as they relate to the use of prescribed burning as a management technique in the Buffalo National …


The Role Of Heparin In Acidic Fibroblast Growth Factor Signaling, Rebecca Kerr Dec 2013

The Role Of Heparin In Acidic Fibroblast Growth Factor Signaling, Rebecca Kerr

Graduate Theses and Dissertations

Fibroblast growth factors (FGFs) are a superfamily of 23 heparin-binding proteins. Acidic fibroblast growth factor (FGF1) is a 16 kDa protein that is involved in many important biological processes such as cell differentiation, angiogenesis, and wound healing. FGF1 exhibits its activity by binding to cell-surface tyrosine kinase receptors (FGFRs). In addition to binding to FGFRs, FGF1 binds to heparin/HLGAGs. Heparin is proposed to have two functions: it protects FGFs from degradation by proteases and from thermal denaturation; and upon binding it induces FGF1 oligomerization, which is mandatory for binding to FGFR. However, it remains controversial whether or not heparin is …


Management Of Katahdin Hair Sheep, Elizabeth Ann Backes Dec 2013

Management Of Katahdin Hair Sheep, Elizabeth Ann Backes

Graduate Theses and Dissertations

The objectives of this research were to determine the effects of different management practices on Katahdin hair sheep performance. For experiment 1, over 2 yr, 5, 0.4-ha pastures were allocated randomly to 1 of 2 grazing treatments: 1) Continuous; or 2) 4-cell rotation. Fifty yearling Katahdin ewes (53 ± 0.7 kg initial BW; 3.3 ± 0.09 initial BCS) were stratified by BW and BCS and allocated randomly to pastures in early May. Grazing d, basal cover, forage quantity or quality did not differ across treatments; however, sampling date effects were detected for forage quantity and quality. Beginning and end of …


Quantitative Trait Loci Associated With Waterlogging Tolerance In A Soft Red Winter Wheat Mapping Population, Diana Carolina Ballesteros Benavides Dec 2013

Quantitative Trait Loci Associated With Waterlogging Tolerance In A Soft Red Winter Wheat Mapping Population, Diana Carolina Ballesteros Benavides

Graduate Theses and Dissertations

Waterlogging is caused when water stays superficially in the soil for an extended period of time, creating an anaerobic environment which decreases plant growth and grain yield at maturity. Despite the impact of waterlogging on wheat production both globally and in the southeastern U.S., very little is known about the genetic control of waterlogging tolerance in wheat. The objective of this study was to determine the amount of genetic variation for vegetative stage waterlogging tolerance present within a wheat recombinant inbred line (RIL) population and to identify quantitative trait loci (QTL) associated with tolerance and productivity. Experiments were carried out …


Effect Of Electrostatic Spraying Of Food-Grade Organic And Inorganic Acids, And Grape Seed Extract On Salmonella Typhimurium And Escherichia Coli O157:H7 On Spinach And Iceberg Lettuce, Vijayalakshmi Ganesh Dec 2013

Effect Of Electrostatic Spraying Of Food-Grade Organic And Inorganic Acids, And Grape Seed Extract On Salmonella Typhimurium And Escherichia Coli O157:H7 On Spinach And Iceberg Lettuce, Vijayalakshmi Ganesh

Graduate Theses and Dissertations

The safety of fresh produce is often challenged by the sporadic incidences of outbreaks owing to Salmonella Typhimurium (S.T.) and Escherichia coli O157:H7 (E.c.). Washing and current disinfection strategies do not completely decontaminate leafy greens such as spinach and iceberg lettuce. Therefore, more effective treatments are essential to ensure the microbial safety of the produce at the selling point. Here, a multiple hurdle approach was applied: (1) Natural antimicrobials - organic acids (malic, lactic and tartaric acids; MA, LA, TA, respectively) and plant extract (grape seed extract, GSE) and (2) Application method - Electrostatic spraying, was …


Ecological Importance Of Ectomycorrhizal Linkages In The Ozark Mountains And The Fernow Experimental Forests, Shelly Kendra Bursick Dec 2013

Ecological Importance Of Ectomycorrhizal Linkages In The Ozark Mountains And The Fernow Experimental Forests, Shelly Kendra Bursick

Graduate Theses and Dissertations

Underground stem-to-stem linkages involving ectomycorrhizal (ECM) fungi are probably important in forest ecosystems, since these linkages could assist in the survival of established trees as well as increasing the growth and development of seedlings and saplings. This study compared forest communities of the Ozark Mountains of northwest Arkansas and the Fernow Experimental Forest in West Virginia by examining species richness, diversity, relative abundance, and the potential for stems to exhibit spatial distribution and clustering patterns that reflected the existence of linkages by ECM fungi. Data on forest communities in the Ozarks were obtained from eight plot locations in Devil's Den …


Electrostatic Spray Application Of Food-Grade Organic Acids And Plant Extracts To Decrease Escherichia Coli O157:H7 And Salmonella Typhimurium On Select Produce, Leighanna Maeree Massey Dec 2013

Electrostatic Spray Application Of Food-Grade Organic Acids And Plant Extracts To Decrease Escherichia Coli O157:H7 And Salmonella Typhimurium On Select Produce, Leighanna Maeree Massey

Graduate Theses and Dissertations

Both consumers and suppliers have been negatively affected by an increase in foodborne pathogens contaminating fruits. Consequently, there is a need for the development of more efficient antimicrobials and application techniques to decrease contamination. Natural preservatives such as organic acids and plant extracts have demonstrated promising results in decontaminating produce. In addition, the effectiveness of such preservatives may be enhanced by the use of an electrostatic sprayer. The objective of this research was to determine the combinations and concentrations of organic acids and plant extract that were able to reduce Salmonella Typhimurium (ST) and Escherichia coli O157:H7 (EC) inoculated fruits …


A Comparison Of Milled Rice Fissuring Kinetics Of Hybrid And Pureline Cultivars, Semehar Haile Tesfaye Dec 2013

A Comparison Of Milled Rice Fissuring Kinetics Of Hybrid And Pureline Cultivars, Semehar Haile Tesfaye

Graduate Theses and Dissertations

Over the past decade, the use of hybrid rice cultivars has greatly increased, and this has led to questions about the processing behavior of hybrid cultivars. This study compares the milled rice fissuring kinetics of hybrid and pureline cultivars. Also, this study elucidates the effects of kernel type (long-grain vs. medium-grain rice cultivars), surface lipid content (SLC), and kernel thickness on fissuring rates.

Three hybrid (CL XL745, CL XL729 and XL753) and five pureline (Wells, CL151, Cheniere, Jupiter and CL261) cultivar lots were procured. Jupiter and CL261 are medium-grain cultivars, whereas the rest are long-grain cultivars. Two experiments were conducted. …


Post-Exercise And Post-Recovery Blood Lactate In Peripheral Arterial Disease, Rebecca Kate Roderick Dec 2013

Post-Exercise And Post-Recovery Blood Lactate In Peripheral Arterial Disease, Rebecca Kate Roderick

Graduate Theses and Dissertations

The purpose of this study was to observe how the presence of peripheral arterial disease affects the level of post-exercise blood lactate and post-recovery blood lactate during and following the six-minute walk test (6MWT). The 6MWT was administered to 49 participants (33 classified as Non-PAD and 16 classified as PAD) over the age of 50 with no uncontrolled cardiovascular or metabolic diseases or a cardiovascular event in the previous 6 months. Results demonstrated that no significant statistical difference exists between the presence of PAD and resting blood lactate (F = 0.86, p = .36), post-exercise blood lactate (F= 0.48, p …


Evaluating Economic Impacts Of Switchgrass Harvest Time, Nathanial Elsworth Cahill Dec 2013

Evaluating Economic Impacts Of Switchgrass Harvest Time, Nathanial Elsworth Cahill

Graduate Theses and Dissertations

This thesis deals with cost of production for cellulosic energy crops of switchgrass, miscanthus, and energy sorghum. The first chapter explains the rationale for development of decision support software called Energy Crop Analysis & Planning (ENCAP) and Switchgrass Harvest Date, Yield, Nutrient Removal Estimator (SHYNE). The second chapter examines harvest date implications on yield, nutrient removal, opportunity cost of modified sale dates, and post-harvest storage losses. This harvest date analysis leads to a profit maximizing harvest date from the perspective of the producer. While this harvest date may be optimal for the producer, biorefineries may be interested in sourcing switchgrass …


Risk Return Of Farmer-Elevator Contracts For Soybeans And Corn In Arkansas, Marei Undine Houpert Dec 2013

Risk Return Of Farmer-Elevator Contracts For Soybeans And Corn In Arkansas, Marei Undine Houpert

Graduate Theses and Dissertations

In Arkansas the contribution of Agriculture to the states GDP is comparatively high. To help farmer's return risk the grain industry developed several marketing tools to support farmers. Literature in this research field finds different results for different locations, commodities, marketing tools and marketing years. As Agriculture in Arkansas is important for its economy this study focuses on soybeans and corn produced in the fertile north-eastern area of Arkansas that uses Memphis Tennessee as a spot market palace. The examined marketing tools are pre-harvest futures hedges and forward contracts as well as post-harvest storage strategies and minimum price contracts. All …


Identification Of Biomarkers Associated With Ascites Incidence In Broilers, Kaylee Rowland Dec 2013

Identification Of Biomarkers Associated With Ascites Incidence In Broilers, Kaylee Rowland

Graduate Theses and Dissertations

Poultry is key in genetic research due to breeding feasibility, relatively short generation interval, and distinct phenotypes. It is estimated that 8% of broiler deaths annually can be attributed to ascites, an economically important disease that has been challenging the industry for the past 2 decades. Genetically selected ascites resistant (RES) and susceptible (SUS) chicken lines have been established and maintained by the University of Arkansas, Fayetteville. Intensive research efforts have been made to reveal physiological and biochemical characteristics for the incidence of ascites. Since the whole genome of the major ancestral chicken, the Red Jungle Fowl, has been sequenced, …


Physical And Biochemical Factors Affecting Breast Fillet Tenderness In Broilers Reared For Divergent Market Demands, Valerie Belle Brewer Dec 2013

Physical And Biochemical Factors Affecting Breast Fillet Tenderness In Broilers Reared For Divergent Market Demands, Valerie Belle Brewer

Graduate Theses and Dissertations

Market trends have dictated that broilers be reared for divergent market demands for decades. Also, broiler genetic strains have been adapted to meet market demands which include: genetic selection for improved breast meat, the practice of growing birds to older ages and greater market weights to meet demands, and decreasing postmortem (PM) aging time to improve processing efficiency and fillet yield. These production practices can also affect product quality, specifically boneless breast fillet tenderness and water-holding capacity. To address these factors, a series of experiments were conducted to determine the effect of strain and slaughter age on meat quality parameters, …


Greater Sage-Grouse (Centrocercus Urophasianus) Habitat Selection In Northwestern Wyoming And Stable Isotope Analysis Of Fecal Material, Andrea Renee Green Dec 2013

Greater Sage-Grouse (Centrocercus Urophasianus) Habitat Selection In Northwestern Wyoming And Stable Isotope Analysis Of Fecal Material, Andrea Renee Green

Graduate Theses and Dissertations

Dramatic range-wide declines in Greater Sage-Grouse populations have prompted efforts to determine habitat characteristics that are selected by sage-grouse for foraging, nesting and brood-rearing areas in an effort to conserve this species. Managers at Heart Mountain and Y U Bench in northwestern Wyoming expressed the need to quantify various habitat characteristics and to determine key use areas at both study sites. Data were collected on a variety of habitat variables in spots selected by grouse for foraging, nesting, and brood-rearing activities. These variables were compared to the same variables measured at random points at both study sites. Significant differences existed …


The Development Of A Traumatic Brain Injury Bioreactor, Zachery Heller Dec 2013

The Development Of A Traumatic Brain Injury Bioreactor, Zachery Heller

Graduate Theses and Dissertations

Approximately 1.7 million Americans experience a traumatic brain injury (TBI) each year. Concussive injuries are a subset of TBI in which blows to the head cause the brain to collide against the interior of the skull. Damage to the neurons, supporting cells, and surrounding extra cellular matrix resulting from these collisions can lead to permanent physical, cognitive, and psychological impairment. We believe the prevalence and clinical significance of concussive injures warrants research investment. To study brain injury following TBI, in vivo models have been the gold standard for TBI experiments. Although a valuable research alternative, animals are expensive, raise ethical …