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Nova Southeastern University

Cardiovascular disease

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Ace2/Ang1-7 Mas Axis: The Counter-Regulator Of The Classical Renin Angiotensin System, Widelyne Dorsainval Feb 2020

Ace2/Ang1-7 Mas Axis: The Counter-Regulator Of The Classical Renin Angiotensin System, Widelyne Dorsainval

Mako: NSU Undergraduate Student Journal

To maintain homeostasis, the renin-angiotensin system (RAS) works to regulate the cardiovascular, renal, respiratory, and neurological systems of the body. However, there is evidence that abundant amounts of certain components of the RAS have detrimental effects and enhance disease. Recent studies have proved that there is a lesser known RAS which acts to counterbalance the classical RAS. To better understand their interaction, the effects of the alternate RAS against the classical RAS in the homeostatic systems of the body are researched and analyzed. The classical pathway employs these components: angiotensin converting enzyme (ACE), angiotensin II (AngII), and angiotensin II type …


Hyperinsulinemia, Cancer And Maqui Berry: The Promise Of Nutritional Supplementation, Brett Deters, Mir Saleem Sep 2019

Hyperinsulinemia, Cancer And Maqui Berry: The Promise Of Nutritional Supplementation, Brett Deters, Mir Saleem

Biology Faculty Articles

Nutritional supplementation has long been studied as a possible treatment alternative or as an adjunct to the standard treatments for common ailments and diseases. According to the latest research, the Chilean maqui berry, Aristotelia chilensis, has been shown to reduce postprandial insulin levels by as much as fifty percent. The berry, which has been shown to be as effective as metformin at increasing insulin sensitivity and controlling blood glucose levels, follows a simple mechanism of action that involves the inhibition of sodium dependent glucose transporters in the small intestine, slowing the rate at which sugars enter the bloodstream and thereby …