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Articles 1 - 26 of 26
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Comparison Of Eight Published Models For Estimating Vancomycin Clearance From Creatinine Clearance In Thai Adult Patients, Aim-On Pradoo, Thitima Wattanavijitkul, Darunee Chotiprasitsakul, Duangchit Panomvana
Comparison Of Eight Published Models For Estimating Vancomycin Clearance From Creatinine Clearance In Thai Adult Patients, Aim-On Pradoo, Thitima Wattanavijitkul, Darunee Chotiprasitsakul, Duangchit Panomvana
The Thai Journal of Pharmaceutical Sciences
This prospective study was performed to determine the best published model for estimating vancomycin clearance from creatinine clearance (CLcr) in Thai adult patients with CLcr greater than or equal to 30 ml/min. Data from 36 adult patients, who were giv...
Acute Effects Of Hot Red Chili On Autonomic And Metabolic Functions In Healthy Subjects, Kannikar Chatsantiprapa, Cameron Hurst, Kaewjai Thepsuthammarat, Nutcharee Thapunkaw, Wilaiwan Khrisanapant
Acute Effects Of Hot Red Chili On Autonomic And Metabolic Functions In Healthy Subjects, Kannikar Chatsantiprapa, Cameron Hurst, Kaewjai Thepsuthammarat, Nutcharee Thapunkaw, Wilaiwan Khrisanapant
The Thai Journal of Pharmaceutical Sciences
To investigate if chili consumption as a food ingredient in a fried rice meal would have any real acute pharmacological effects on autonomic nervous system (ANS) and metabolic system (MS), a randomized, cross-over, intervention trial was conducted in 33 ...
Development And Validation Of Rp-Hplc Method For Analysis And Stability Study Of 8-Carboxyphenyl-2'-Deoxyguanosine And 8-Bromo-2'-Deoxyguanosine, Kulwadee Sawatpaiboontawee, Panutsaya Sermthaveesub, Panuwat Sangsirimongkolying, Patratorn Kunakorntham, Sudarat Thongborriboon, Bodin Tuesuwan, Vorasit Vongsutilers
Development And Validation Of Rp-Hplc Method For Analysis And Stability Study Of 8-Carboxyphenyl-2'-Deoxyguanosine And 8-Bromo-2'-Deoxyguanosine, Kulwadee Sawatpaiboontawee, Panutsaya Sermthaveesub, Panuwat Sangsirimongkolying, Patratorn Kunakorntham, Sudarat Thongborriboon, Bodin Tuesuwan, Vorasit Vongsutilers
The Thai Journal of Pharmaceutical Sciences
Modifications on C8 position of purine base have been studied for their effects on B-DNA to Z-DNA conversion. The 8-bromo and 8-carboxyphenyl adduct are among the most potent Z-DNA facil tators and hence arc aimed to be utilized for Z-DNA based probe lor...
Comparative Study Of Postmortem Blood, Urine And Vitreous Humor Methamphetamine, Rungtip Narapanyakul, Wichian Tungtananuwat, Patramon Yongpanich, Theerin Sinchai, Nantana Thong-Ra-Ar, Somsong Lawanprasert
Comparative Study Of Postmortem Blood, Urine And Vitreous Humor Methamphetamine, Rungtip Narapanyakul, Wichian Tungtananuwat, Patramon Yongpanich, Theerin Sinchai, Nantana Thong-Ra-Ar, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
Methamphetamine (MA) is a highly addictive and toxic central nervous system stimulant. Urine samples are used as evidences of MA abuse under the Narcotics Laws, whereas blood samples are specimens for investigation of MA poisoning. However, both specimen...
Association Of Genetic Variants In Ugt1a6 Genes And Non-Genetic Variant With Valproic Acid Doses And Plasma Concentration In Thai Epileptic Patients, Salinthip Aphichartphunkawee, Yotin Chinvarun, Pornpimol Kijsanayotin
Association Of Genetic Variants In Ugt1a6 Genes And Non-Genetic Variant With Valproic Acid Doses And Plasma Concentration In Thai Epileptic Patients, Salinthip Aphichartphunkawee, Yotin Chinvarun, Pornpimol Kijsanayotin
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to investigate the association of genetic variants in UGT1A6 19T>G, 541A>G and 552A>C together with non-genetic variant with VPA dose and plasma concentrations in Thai epileptic patients. Eighty four Thai epileptic patients who ...
Stability Indicating Rp-Hplc Method For Estimation Of Bamifylline Hydrochloride In Tablet Formulation: Development And Validation Consideration, Rashmin. B. Patel, Mrunali. R. Patel, Tapan S. Goswami
Stability Indicating Rp-Hplc Method For Estimation Of Bamifylline Hydrochloride In Tablet Formulation: Development And Validation Consideration, Rashmin. B. Patel, Mrunali. R. Patel, Tapan S. Goswami
The Thai Journal of Pharmaceutical Sciences
A simple, specific and robust stability indicating high performance liquid chromatographic (HPLC) method for estimation of bamifylline hydrochloride was developed and validated. Bamifylline hydrochloride was separated and quantitated on Inertsil ODS-3V c...
Protective Effect Of Deferiprone On 7-Ketocholesterol Formation In Hemin-Induced Ldl Oxidation, Usa Suwannasual, Thitima Pengsuparp, Rataya Luechapudiporn
Protective Effect Of Deferiprone On 7-Ketocholesterol Formation In Hemin-Induced Ldl Oxidation, Usa Suwannasual, Thitima Pengsuparp, Rataya Luechapudiporn
The Thai Journal of Pharmaceutical Sciences
Hemin (iron (III)-protoporphyrin IX) is found that it is elevated in the plasma of thalassemic patients and is a possible cause of oxidative stress-promoting atherosclerosis. Deferiprone (L1), an iron chelator, can prevent free radical formation catalyze...
Understanding The Medication Experiences Of Thai Patients Attending A Medication Therapy Management Clinic, Phantipa Sakthong, Win Winit-Watjana, Rungpetch Sakulbumrungsil
Understanding The Medication Experiences Of Thai Patients Attending A Medication Therapy Management Clinic, Phantipa Sakthong, Win Winit-Watjana, Rungpetch Sakulbumrungsil
The Thai Journal of Pharmaceutical Sciences
The study aimed to explore Thai patients' medication experiences in five domains, i.e., attitudes, understanding, expectations and wants, concerns, and convenience of medicine use. This cross-sectional descriptive study was carried out using a qualitativ...
Evaluation Of Antioxidant And Free Radical Scavenging Activities Of Different Fractions Of Pterospermum Suberifolium Leaf Extract, Dibyajyoti Saha, Swati Paul
Evaluation Of Antioxidant And Free Radical Scavenging Activities Of Different Fractions Of Pterospermum Suberifolium Leaf Extract, Dibyajyoti Saha, Swati Paul
The Thai Journal of Pharmaceutical Sciences
The study was aimed an evaluating the antioxidant activities of the various leaf extracts (ethyl acetate, n- butanol and chloroform) of Pterospermum suberifolium by using various in vitro antioxidant assays. The total polyphenols were also determined spe...
Determination Of Retinol And Alpha-Tocopherol In Avocado Nanoemulsion With Monolithic Column, Wisanu Thongchai
Determination Of Retinol And Alpha-Tocopherol In Avocado Nanoemulsion With Monolithic Column, Wisanu Thongchai
The Thai Journal of Pharmaceutical Sciences
A high performance liquid chromatographic procedure was developed for separation of retinol and a-tocopherol from avocado oil. The extraction methods were studied to extract of oil from avocado sample. This method was developed and validated for various ...
A New Rp-Hplc Method For Estimation Of Clindamycin And Adapalene In Gel Formulation: Development And Validation Consideration, Rohit. H. Khatri, Rashmin. B. Patel, Mrunali R. Patel
A New Rp-Hplc Method For Estimation Of Clindamycin And Adapalene In Gel Formulation: Development And Validation Consideration, Rohit. H. Khatri, Rashmin. B. Patel, Mrunali R. Patel
The Thai Journal of Pharmaceutical Sciences
This paper describes a validated high-performance liquid chromatographic (HPLC) method for simultaneous estimation of clindamycin (CLI) and adapalene (ADA) in pure powder and gel formulation. The HPLC separation was achieved on a Luna C18 (2) (250 x 4.6 ...
Gigantol-Induced Apoptosis In Lung Cancer Cell Through Mitochondrial-Dependent Pathway, Sopanya Charoenrungruang, Pithi Chanvorachote, Boonchoo Sritularak, Varisa Pongrakhananon
Gigantol-Induced Apoptosis In Lung Cancer Cell Through Mitochondrial-Dependent Pathway, Sopanya Charoenrungruang, Pithi Chanvorachote, Boonchoo Sritularak, Varisa Pongrakhananon
The Thai Journal of Pharmaceutical Sciences
Lung cancer is identified as a major cause of cancer-related death. Death in this cancer associates with the acquisition of apoptosis avoidance mechanism. Apoptosis, a programmed cell death mechanism, plays an important role on normal cell development an...
Authentication Of A Thai Crude Drug "Kot-Chula-Lumpa" Using Gas Chromatography-Mass Spectrometry And Multivariate Data Analysis, Jankana Burana-Osot, Panadda Phattanawasin, Sununta Srisopon, Praveen Kumar Ashok, Baokang Huang, Uthai Sotanaphun
Authentication Of A Thai Crude Drug "Kot-Chula-Lumpa" Using Gas Chromatography-Mass Spectrometry And Multivariate Data Analysis, Jankana Burana-Osot, Panadda Phattanawasin, Sununta Srisopon, Praveen Kumar Ashok, Baokang Huang, Uthai Sotanaphun
The Thai Journal of Pharmaceutical Sciences
Kot-chula-lumpa is a crude drug of Thai traditional medicine for fever remedy. To authenticate its botanical origin, gas chromatogram of its non-polar constituents was analysed and compared with those of authentic samples by using chemometric tools. Fing...
Molecular Binding Modes Of Diarylheptanoids From Curcuma Comosa On The Er-Ss Receptor, Nathjanan Jongkon, Prasan Tangyuenyongwatana
Molecular Binding Modes Of Diarylheptanoids From Curcuma Comosa On The Er-Ss Receptor, Nathjanan Jongkon, Prasan Tangyuenyongwatana
The Thai Journal of Pharmaceutical Sciences
Curcuma comosa Roxb. is a medicinal plant that belongs to the Zingiberaceae family. The plant has been used in traditional Thai medicine for the treatment of postpartum uterine bleeding. The major compounds found in this plant are diarylheptanoids, which...
Development And Evaluation Of Transdermal Patches Of Aceclofenac, Animesh Gairola, Urmi Chaurasia, Anupama Singh, Vikas Anand Saharan
Development And Evaluation Of Transdermal Patches Of Aceclofenac, Animesh Gairola, Urmi Chaurasia, Anupama Singh, Vikas Anand Saharan
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to develop and evaluate matrix-type transdermal therapeutic system containing aceclofenac with different ratios of hydrophilic polymers (hydroxylpropyl methylcellulose, sodium carboxy methylcellulose) and a hydrophobic polymer (...
Synthesis And Biological Screening Of Some Thienyl And Phenyl Pyrazoline Derivatives As Antimalarial Agent, Abdu Tuha, Adnan A. Bekhit, Yimer Seid
Synthesis And Biological Screening Of Some Thienyl And Phenyl Pyrazoline Derivatives As Antimalarial Agent, Abdu Tuha, Adnan A. Bekhit, Yimer Seid
The Thai Journal of Pharmaceutical Sciences
Malaria is a common parasitic disease of the developing world and drug resistance has hindered their efficient control. Pyrazole derivatives were synthesized using aldol condensation and subsequent cyclization reactions. The compounds were synthesized in...
Balancing Accountability For Adverse Drug Reactions Under American Product Liability Law: Lessons For Thailand?, Sakda Thanitcul, Matthew Lim Braslow
Balancing Accountability For Adverse Drug Reactions Under American Product Liability Law: Lessons For Thailand?, Sakda Thanitcul, Matthew Lim Braslow
The Thai Journal of Pharmaceutical Sciences
Drugs that are powerful enough to cure disease are powerful enough to do potential harm. This common saying among physicians is the central point of this paper. When harm to a patient does occur, the sense of society requires that where and when appropri...
In Silico Prediction Of Interaction Between Flavonoids Of Propolis Of Honey Bee And Anthrax Protective Antigen, Shahin Gavanji, Mohsen Doostmohammadi, Behrouz Larki
In Silico Prediction Of Interaction Between Flavonoids Of Propolis Of Honey Bee And Anthrax Protective Antigen, Shahin Gavanji, Mohsen Doostmohammadi, Behrouz Larki
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to check the interaction between four ligands (Acacetin, Chrysin, Naringenin and Caffeic Acid Phenethyl Ester) and protective antigen. These ligands are the main flavonoids of propolis of honey. Bioinformatics checking was done ...
Bioequivalence Study Of Abacavir 300 Mg Tablets In Healthy Thai Male Volunteers Under Fasting Conditions, Isariya Techatanawat, Chutima Manamuti, Jaturavit Vattanarongkup, Polsak Teerawonganan, Ekawan Yoosakul, Wiwat Supasena, Bancha Chuasuwan, Piengthong Narakorn, Ponanee Puranaoti
Bioequivalence Study Of Abacavir 300 Mg Tablets In Healthy Thai Male Volunteers Under Fasting Conditions, Isariya Techatanawat, Chutima Manamuti, Jaturavit Vattanarongkup, Polsak Teerawonganan, Ekawan Yoosakul, Wiwat Supasena, Bancha Chuasuwan, Piengthong Narakorn, Ponanee Puranaoti
The Thai Journal of Pharmaceutical Sciences
Abacavir is an antiretroviral drug that can be prescribed in single dose or in fixed-dose combination formulations to make adherence easier. Due to this advantage, a generic product of abacavir of GPO has been developed with lower price and would be bene...
Relationship Between Methamphetamine Concentrations In Hair Root, Blood And Urine Samples In Postmortem Cases, Sirirat Phomhitatorn, Theerin Sinchai, Nantana Thongra-Ar, Somsong Lawanprasert
Relationship Between Methamphetamine Concentrations In Hair Root, Blood And Urine Samples In Postmortem Cases, Sirirat Phomhitatorn, Theerin Sinchai, Nantana Thongra-Ar, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
Urine and blood samples are normally used to determine methamphetamine (MA) level in forensic and clinical toxicology for assessment of illicit MA use. In cases in which both samples are unavailable or contaminated, hair root has been proposed as an alte...
Antinociceptive And Anti-Inflammatory Activities Of Tree-Phon-Thad Remedy, Sunisa Deeoun, Pravaree Phuneerub, Chanida Palanuvej, Nijsiri Ruangrungsi, Pasarapa Towiwat
Antinociceptive And Anti-Inflammatory Activities Of Tree-Phon-Thad Remedy, Sunisa Deeoun, Pravaree Phuneerub, Chanida Palanuvej, Nijsiri Ruangrungsi, Pasarapa Towiwat
The Thai Journal of Pharmaceutical Sciences
Tree-Phon-Thad remedy is used as an antipyretic and anti-inflammatory agent by traditional practitioners in Thailand, and includes roots of Zingiber zerumbet (Kra-Thue), Zingiber montamum (Plai) and Cymbopogon nadus (Ta-Krai-Hom). In this study, the anti...
Identification And Antimicrobial Activity Of Streptomyces Strains From Thai Mangrove Sediment, Wongsakorn Phongsopitanun, Khanit Suwanborirux, Somboon Tanasupawat
Identification And Antimicrobial Activity Of Streptomyces Strains From Thai Mangrove Sediment, Wongsakorn Phongsopitanun, Khanit Suwanborirux, Somboon Tanasupawat
The Thai Journal of Pharmaceutical Sciences
Two actinomycete strains, D2-1 and D2-2, were isolated from mangrove sediment sample collected from Samut Song Kram province, Thailand. On the screening of antimicrobial activity, the crude extracts of fermentation broth of both strains exhibited activit...
Evaluation Of Analgesic Activity Of Hydroalcoholic Extract Of Ipomoea Staphylina, Soumyadeep Ghosh, M Firdous
Evaluation Of Analgesic Activity Of Hydroalcoholic Extract Of Ipomoea Staphylina, Soumyadeep Ghosh, M Firdous
The Thai Journal of Pharmaceutical Sciences
This study has been attempted to evaluate analgesic property of hydroalcoholic extract of leaves of Ipomoea staphylina. Analgesic activity was evaluated by abdominal writhing, formalin-induced paw licking method and Eddy's hot plate test in mice. The hyd...
Verification Of Using Saliva As An Alternative To Serum For Topiramate Monitoring, Jareerut Kongrit, Yotin Chinvarun, Nuansri Niwattisaiwong, Somsong Lawanprasert
Verification Of Using Saliva As An Alternative To Serum For Topiramate Monitoring, Jareerut Kongrit, Yotin Chinvarun, Nuansri Niwattisaiwong, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
This study aims to verify the correlation between serum and saliva topiramate concentrations in Thai patients with epilepsy. Twenty-six subjects were patients aged 17-56 years old who were under treatment with topiramate. Their blood and saliva samples w...
Dissolution Enhancement Of Dronedarone Hydrochloride By Complexation With Ss-Cd And Hp Ss-Cd: Dissolution And Physicochemical Characterization, Anjan Kumar Mahapatra, Supriya Samoju, Ruchita Kumari Patra, Padala Narasimha Murthy
Dissolution Enhancement Of Dronedarone Hydrochloride By Complexation With Ss-Cd And Hp Ss-Cd: Dissolution And Physicochemical Characterization, Anjan Kumar Mahapatra, Supriya Samoju, Ruchita Kumari Patra, Padala Narasimha Murthy
The Thai Journal of Pharmaceutical Sciences
The study was aimed to improve solubility or dissolution characteristics of dronedarone hydrochloride by preparing its inclusion complexes (ICs) with ß-cyclodextrin (ß-CD) and hydroxypropyl ß-cyclodextrin (HP ß-CD). The phase solubility behavior of d...
Short-Term Safety And Efficacy Of Fish-Oil Emulsions On The Prevention Of Parenteral Nutrition-Associated Liver Disease In Surgical Neonates: A Randomized Controlled Trial, Jrarat Ariyawangso, Chankit Puttilerpong, Suntaree Ratanachu-Ek, Maitree Anuntkosol
Short-Term Safety And Efficacy Of Fish-Oil Emulsions On The Prevention Of Parenteral Nutrition-Associated Liver Disease In Surgical Neonates: A Randomized Controlled Trial, Jrarat Ariyawangso, Chankit Puttilerpong, Suntaree Ratanachu-Ek, Maitree Anuntkosol
The Thai Journal of Pharmaceutical Sciences
Surgical neonates requiring prolonged parenteral nutrition (PN) are at risk for parenteral nutrition-associated liver disease (PNALD) that contributes to an increase in morbidity and mortality in surgical infants. Current lipid emulsions used with neonat...