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Growing South Dakota (Fall 2026), College Of Agriculture, Food And, Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Support from donors helping set SDSU dairy graduates above the rest
[Page] 4 A decade of impact: Celebrating 10 years of cow-calf, swine education and research facilitates
[Page] 8 98-year-old donor keeps decades-long scholarship going in honor of late husband
[Page] 11 Looking back at Michele Dudash's tenure in academia
[Page] 12Giving students opportunities, experience to build their futures
[Page] 16 A Jackrabbit's journey in growing agricultural leadership
[Page] 18 Building South Dakota's next generation of rural veterinarians
[Page] 19 Conservation: A family affair
[Page] 20 South Dakota Water Resources Institute finds solutions to South Dakota's water challenges …

Effects Of Dietary Nigella Sativa Supplementation On Growth Performance, Lipid Profile, Carcass Traits, And Immune Response Of Broiler Chickens During Summer And Winter Seasons, Zahida Jabeen, Roheela Yasmeen

Journal of Bioresource Management

The poultry industry is a major agro-based sector in Pakistan and an important source of meat protein. Nigella sativa (black cumin/kalonji) has gained attention as a natural feed additive because of its antimicrobial, antioxidant, immunomodulatory, and growth-promoting properties. This study evaluated the effects of dietary Nigella sativa seed supplementation on growth performance, feed conversion ratio (FCR), lipid profile, and carcass characteristics of broiler chickens under summer and winter conditions. A total of 120 one-day-old broiler chicks were randomly assigned to two dietary treatments, with 60 birds per treatment and three replicates of 20 birds. The control group received a basal …

Genetic Improvement Of Wheat (Triticum Aestivum L.) For Enhancing Grain Yield And Adaptability Under Changing Climate, Muhammad Umer Farooq, Fida Hussain, Mehvish Makhdoom, Najaf Batool, Javed Ahmad, Muhammad Ibrahim Khan, Minahel Shahzadi

Journal of Bioresource Management

Wheat (Triticum aestivum L.) is a fundamental major crop that serves a critical role in ensuring worldwide food availability and sustainability, particularly in developing countries such as Pakistan. Its productivity and yield stability are increasingly threatened by climate change induced stresses such as heat, drought, salinity, evolving pests and disease dynamics. These abiotic and biotic stresses disturb key biological and developmental processes, consequently leading to a decline in grain production and quality. This review synthesizes recent advances in wheat genetic improvement, focusing on breeding strategies and emerging technologies for enhancing grain yield and climate resilience. i.e., how genetic variation, …

Phosphoric Acid-Mediated Regeneration Of Sugarcane Bagasse Cellulose-Rich Fraction For Enzymatic Production Of Water-Soluble Cellulosic Oligomers, Chiou-Yeong Saw, David Agus Setiawan Wibisono, Tsung-Yen Wu, Yung Chang, Chi-Fai Chau

Journal of Food and Drug Analysis

An integrated strategy was developed to promote conversion of a sugarcane bagasse cellulose-rich fraction into water-soluble cellulosic oligomers (WCOs) through phosphoric acid-mediated regeneration and enzymatic hydrolysis. Alkaline pretreatment on sugarcane bagasse powder increased glucan content from 57.6 to 93.4 g/100 g sample and lowered Klason lignin to 6.1 g/100 g sample. Phosphoric acid-mediated regeneration was subsequently capable of reorganizing the structure of cellulose from sugarcane bagasse, resulting in a decrease of crystallinity from 72.9 to 64.0% and introducing cellulose II-like features. The hydration state of regenerated cellulose strongly influenced hydrolysis performance, as the hydrated form showed significantly higher solubilization (810.4 …

Simultaneous Determination Of Eight Sweeteners In Glycyrrhizin By Ultrahigh Performance Liquid Chromatograph-Tandem Mass Spectrometry, He Liang, Zhu Lingchao, Hu Ruilin, Zhang Tao, Song Chunman

Food and Machinery

[Objective] To establish a method based on ultrahigh performance liquid chromatography-tandem mass spectrometry for rapid determination of eight sweeteners in glycyrrhizin. [Methods] The sample is ultrasonically extracted with 20 mL pure water for 30 min, passed through a 0.22 μm microporous filter membrane, separated through the Waters HSS T3 column, subjected to gradient elution with 0.2% (V/V) ammonia solution-methanol, and detected under the negative mode of electrospray ionization. [Results] The eight sweeteners showed a good linear relationship between peak area and concentration within the range of 0.1–20.0 μg/mL, with correlation coefficients greater than 0.99. The limits of quantification are within …

Preparation Of Agaricus Bisporus Chitosan Nanoliposomes And Their In Vitro Hypoglycemic Effects, Chen Yanzhi, Zhang Jiawen, Zhang Molan, You Lijun

Food and Machinery

[Objective] To address the limited oral utilization of metformin hydrochloride (MET) and the insufficient delivery efficiency of conventional liposomes, MET-loaded nanoliposomes modified with Agaricus bisporus chitosan (ACS) (ACS-modified liposomes, A-M-L) were developed, and their physicochemical properties, storage stability, cytocompatibility, and effects on glucose consumption by HepG2 cells were evaluated. [Methods] ACS was used as a substitute for crustacean chitosan to prepare MET-loaded nanoliposomes using the thin-film dispersion-ultrasonication method. The structural characteristics and microscopic morphology were observed by Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM), and particle size, polydispersity index (PDI), zeta potential, encapsulation efficiency, storage stability, cytotoxicity, …

Correlation Between Thermal Characteristics And Fat Concomitants And Flavor Quality In The Refining Process Of Camellia Oleifera Seed Oil, Liu Zhaofan, Liu Jiabao, Li Hang, Huang Zonghai, He Xinyi, Li Yun

Food and Machinery

[Objective] To investigate the correlation between thermal characteristics, fat concomitants, and flavor quality during the refining process of Camellia oleifera seed oil, and to provide a theoretical basis for precise regulation of the refining process. [Methods] Oil samples were collected during the refining process (crude oil, alkali refining, decolorization, deodorization, and winterization). The dynamic changes in physicochemical indexes, thermal characteristics, fat concomitants, fatty acid composition, and volatile flavor substances were systematically determined, and their correlations were analyzed. [Results] The refining process reduced the acid value of C. oleifera seed oil from 1.79 mg/g to 0.26 mg/g and the peroxide value …

Extrusion Pretreatment Improves The Protein Digestibility Of Black Soybean Meal And Its Effects On The Final Quality And Antioxidant Activity Of Soy Sauce, Cheng Xiaoyuan, Ma Chengye, Li Hongjun

Food and Machinery

[Objective] To investigate the regulatory mechanisms of extrusion pretreatment on the protein digestibility of black soybean meal and systematically evaluate its effects on soy sauce quality and antioxidant activity. [Methods] A mixture of black soybean meal and flour was pretreated using extrusion technology for soy sauce brewing. Extrusion temperature, screw speed, flour addition, and moisture content were selected as the main process parameters to investigate their effects on protein digestibility. Under the optimal extrusion conditions, the raw materials were prepared and further subjected to simulated low-salt solid-state soy sauce fermentation. Amino nitrogen, total nitrogen, reducing sugar, pH, total acid, ammonium …

Effects And Mechanisms Of Carrageenan-Sodium Caseinate Interactions On Oil-Water Interfacial Properties, Huang Zequan, Cao Hongfang, He Jian, Wang Caiyun, Zhao Qiangzhong

Food and Machinery

[Objective] To investigate the effects of κ-carrageenan concentration on its interaction with sodium caseinate and the oil-water interfacial properties of the composite system. [Methods] Sodium caseinate composite systems with different κ-carrageenan concentrations were prepared. Protein structure, surface hydrophobicity, endogenous fluorescence, zeta potential, particle size, interfacial adsorption behavior, and interfacial dilatational modulus were determined. [Results] After the addition of κ-carrageenan, the secondary structure of sodium caseinate changed markedly, and the proportion of ordered structures showed a trend of initially increasing and then decreasing. Surface hydrophobicity and endogenous fluorescence intensity exhibited a similar trend. When the addition level of κ-carrageenan was 0.15‰, …

Effects Of Material Form On The Modification Of Rice By Heat-Moisture Treatment, Wang Haoyan, Feng Wei, Zheng Yubin, Wang Ren, Huo Jian

Food and Machinery

[Objective] To investigate the effects of two material forms (rice flour and whole rice grains) on the modification performance of rice by heat-moisture treatment and physicochemical properties. [Methods] Early indica rice is used as raw material. Rice flour and whole rice grains are subjected to heat-moisture treatment (100 ℃, 2 h) under three moisture levels (21%, 24%, and 27%). Subsequently, the basic chemical composition, surface particle morphology, crystal structure characteristics, and farinograph processing properties of samples from the two groups are characterized. [Results] After heat-moisture treatment, the particle dispersibility of samples in both groups decreases significantly, accompanied by obvious aggregation …

Study On Preparation And Emulsification Properties Of Distillers Dried Grains With Solubles Arabinoxylan Hydrolysate/Soy Protein Isolate Complex, Yu Shuo, Guo Qingbin, Zhao Shudi, Li Zhenjing, Jia Xing, Kang Ji

Food and Machinery

[Objective] To expand the application fields of distillers dried grains with solubles and improve its market value. [Methods] Arabinoxylan (AX) was extracted from distillers dried grains with solubles and modified to prepare AX with different molecular structures. AX was then reacted with soy protein isolate (SPI) via the Maillard reaction to prepare the AX-SPI covalent complex. The structure of the complex was characterized using circular dichroism spectroscopy, Fourier transform infrared spectroscopy, particle size, and zeta potential, and its emulsifying properties were studied. [Results] The AX-SPI covalent complex is formed by SPI and AX via the Maillard reaction, and differences in …

Inhibitory Effect Of Tbhq On The Deterioration Of Leisure Dried Tofu, Chen Durun, Huang Zhanrui, Hu Lianhua, Chen Hao, Zhao Dan

Food and Machinery

[Objective] To address key industrial challenges of leisure dried tofu subjected to mild sterilization, namely shortened shelf life (30~90 d) and susceptibility to photoenzyme -induced oxidative deterioration, this study aimed to elucidate the mechanisms by which tert -butylhydroquinone (TBHQ ) inhibits quality deterioration in leisure dried tofu induced by photoenzyme initiators. [Methods] Leisure dried tofu was prepared using marinade treated with TBHQ and photoenzyme initiators (chlorophyll and azodiisobutyronitrile ). During a 90 d storage period, dynamic changes in nutritional components, characteristic oxidation indices, textural properties, intermolecular forces, and microstructure of the dried tofu were systematically monitored.［Results］ During the early storage …

Overexpression Of Liax Enhances Stress Tolerance In Lacticaseibacillus Paracasei L9, Liu Ting, Ma Xiayin, Yan Ningning, Chen Shihao, Bai Jingfu

Food and Machinery

[Objective] To investigate the protective role of the surface protein LiaX in Lacticaseibacillus paracasei L9 against external stresses, such as bile salts, antibiotics, and the gastrointestinal environment. [Methods] A LiaX-overexpressing strain was constructed and the protein was purified. Spent media assays, in vitro simulated digestion, and exogenous protein supplementation experiments were comprehensively employed to evaluate the effect of LiaX on the survival rate of the strain under digestive, bile salt, and antibiotic stresses. [Results] The LiaX-overexpressing strain LPL9psip0968 his was successfully constructed, and the LiaX protein was isolated and purified. Spent media assays and exogenous addition of purified LiaX protein …

Preparation , Structural Characterization , And In Vitro Hypoglycemic Activities Of Acetylated Elaeagnus Moorcroftii Wall . Polysaccharides, Xue Xue, Tang Hui, Liao Bingwu, Chen Lu, Zhao Wenbin, Wang Xinbing, Sun Yan, Wei Youhong

Food and Machinery

[Objective] To explore the preparation conditions, structural information, and in vitro hypoglycemic activities of acetylated Elaeagnus moorcroftii Wall. polysaccharides of Kashgar (A-EMP-K). [Methods] EMP-K is extracted by the water extraction and alcohol precipitation method, and modified by the acetic anhydride method. Then, A-EMP-K preparation conditions are optimized using Box–Behnken response surface methodology. Furthermore, structural characterization and in vitro hypoglycemic activity assays of A-EMP-K are performed. [Results] The optimal preparation conditions are a reaction time of 3 h, a reaction temperature of 61 ℃, and an acetic anhydride addition volume of 9.3 mL. Under these conditions, A-EMP-K exhibits a degree of …

Purification , Characterization , And Hypoglycemic Activity Of Peanut Coat Polyphenols, Zhou Wenda, Yin Yunhui, Fu Jingxuan

Food and Machinery

[Objective] To optimize the purification process of peanut skin polyphenols (PSPs), improve purification efficiency, and investigate their in vitro hypoglycemic activity. [Methods] Three types of PSPs (red, white, and purple) were extracted by ultrasound-assisted ethanol extraction. Seven macroporous resins were used for static adsorption and desorption of PSPs, and the resin with the best performance was selected for single-factor experiments. The components of the purified PSPs were analyzed by UPLC-ESI-QTOF-MS/MS. Using acarbose as a positive control, the inhibitory activity and inhibition types of PSPs against α-amylase and α-glucosidase were investigated. [Results] Purple peanut skins exhibited the highest contents of total …

Effects Of Total Flavonoids From Perilla Leaves On Anti-Fatigue Capacity In Adolescent Athletes, Liu Baofeng, Liang Xiao

Food and Machinery

[Objective] To clarify the improvement effects of total flavonoids from perilla leaves on the anti-fatigue capacity of adolescent athletes and to compare the effects of different purification methods and liquid-to-solid ratios on their efficacy. [Methods] Total flavonoids from perilla leaves were extracted using microwave-assisted extraction, and two purification methods were employed for total flavonoid purification. Male adolescent track and field athletes aged 16 years with comparable physical fitness were selected to participate in a trial involving total flavonoid intake. Exhaustion time, maximum oxygen uptake, and serum lactate, serum urea nitrogen, and creatine kinase levels were measured in the male adolescent …

Effects Of Re-Frying Processes On The Quality And Volatile Flavor Compounds Of Pre-Fried Coated Tofu, Nie Jingwen, Chen Hao, Zhao Dan, Zhou Xiaohu, Yang Dajun, Zhao Liangzhong

Food and Machinery

[Objective] To investigate the effects of deep frying process (DFP), microwave process (MP), and air frying process (AFP) on the quality and aroma characteristics of pre-fried coated tofu. [Methods] The optimal re-frying conditions are selected using slurry exudation rate, moisture content, color difference, and sensory evaluation as indicators. Subsequently, the re-frying method most suitable for consumers is comprehensively determined based on texture properties, oil content, malondialdehyde content, electronic nose analysis, and volatile compound composition. [Results] Under the three re-frying methods, the coated tofu exhibits an increase-then-decrease trend in slurry exudation rate and sensory evaluation, accompanied by a continuous decline in …

Effects Of Frost Mulberry Leaf Powder On Properties Of Dough And Quality Of Bread, Zhang Erfang, Feng Yan, Zhang Yixin

Food and Machinery

[Objective] To explore the effects of frost mulberry leaf powder (FMLP) on the processing characteristics of dough and the quality and storage properties of bread. [Methods] FMLP is blended with wheat flour, and the rheological properties of the dough are analyzed by a rheometer. Bread quality is evaluated in terms of texture, color, specific volume, and sensory attributes. The TOPSIS method is adopted for comprehensive evaluation, and variations in moisture and hardness of bread during storage are compared. [Results] The addition of FMLP increases the G', G", and tanδ of the dough, enhances the hardness and chewiness of the bread, …

Research Progress In Extraction Of Food Functional Ingredients With Subcritical Dimethyl Ether, Wan Xiaofu, Pan Le, Li Muchun

Food and Machinery

With the growing demand for high-quality natural product extracts, dimethyl ether as a new green solvent operating under subcritical conditions has exhibited notable benefits for the extraction of lipids, carotenoids, and long-chain polyunsaturated fatty acids, attributable to its distinctive physicochemical characteristics. This paper reviews the progress in the application of dimethyl ether in natural product extraction, focusing on its advantages in treating biomass with high moisture content, improving extraction efficiency, and reducing energy consumption and environmental load, with a view to providing reference for the application of subcritical dimethyl ether in extraction.

Functional Components And Food Application Progress Of Almond By-Products, Xie Jingyi, Wang Wanqing, Wang Xinyi, Yuan Chunle, Li Yuna, Hua Wei

Food and Machinery

As the global almond industry expands rapidly, large quantities of by-products are generated during processing (such as green hulls, shells, and skins), which are rich in functional constituents including polyphenols, flavonoids, dietary fibers, and volatile aroma compounds. This review summarizes the compositional characteristics and extraction technologies of these by-products, while elucidating their potential applications in food and biomaterials, with a specific focus on their antioxidant properties, bioactivities, and structural features. Furthermore, in light of recent research advances, the review further discusses poor stability, low bioavailability, challenges in processing compatibility, and other problems, proposing enhancement strategies such as nano-delivery, structural modification, …

Research Progress Of 3d Printing Technology In Food Texture Design, Ou Suiling, Xie Zihong

Food and Machinery

Food texture is a key factor influencing consumer acceptance. With the growing demand for personalized and health-oriented diets, the technical bottlenecks of traditional food processing methods have gradually become apparent in texture control and diversified texture presentation. Owing to its flexible and personalized characteristics, 3D printing offers a novel approach for food texture design. This paper reviews the textures that can be personalized and optimized by 3D printing through material modulation, structural modeling, and equipment optimization. Furthermore, this paper analyzes the challenges faced by this technology, including cooking adaptability, food safety assurance, and consumer acceptance, proposing corresponding solutions.

Integration Of Freshness Monitoring And Active Packaging Technologies For Aquatic Products, Maria Ali, Abdul Waheed Ghanghro, Bheem Raj Serani, Mahrukh Zakir

Journal of Food and Drug Analysis

Aquatic products are nutritionally valuable but highly perishable, with quality loss driven by microbial spoilage, biochemical changes, including total volatile basic nitrogen (TVB-N), trimethylamine (TMA) and histamine, and physicochemical deterioration, including lipid oxidation, gas production and texture loss. Conventional packaging slows these processes but does not report real-time freshness. This review analyzes how active packaging (antimicrobial, antioxidant, enzyme-inhibiting, and oxygen-scavenging systems, including bio- and nanocomposites) can be combined with freshness monitoring technologies (colorimetric/pH indicators, gas sensors, biosensors, and digital tools such as radio frequency identification (RFID) and Internet of Things (IoT) systems) specifically for fish, shrimp, and mollusks. We first …

Food Insecurity Among Freshman Male Collegiate Athletes At A Historically Black University In Maryland, Petita Cue Rentz

Walden Dissertations and Doctoral Studies

Food insecurity is an emerging public health issue impacting collegiate student-athletes enrolled at Historically Black Universities (HBUs). Recent research revealed that 63% of football players have reported some form of food insecurity which disproportionately impacts Black athletes at higher rates. The purpose of this qualitative study was to explore the lived experiences and dietary behaviors of freshman male collegiate student-athletes who lacked access to food despite receiving athletic scholarships in a publicly funded HBU in Maryland. The research questions for this qualitative study focused on exploring the lived experiencing of Black male athletes who were experiencing food insecurity at an …

Mindful Parenting And Toddlers' Food Responsiveness: The Role Of Controlling Feeding Practices, Qingyu Jiang, Holly Wilhite, Natalie A. Williams, Dipti A. Dev, Caron A. C. Clark, Pearl Avari, Sarah B. Ladd

Journal of Extension

Controlling feeding practices may negatively impact children's eating behaviors. Mindful parenting may offer a promising way to reduce the use of these practices. This study examined the mediating role of pressuring children to eat and using food as a reward in the association between mindful parenting and toddlers' food responsiveness. Results indicated that higher levels of mindful parenting were associated with lower pressuring to eat, which was related to lower food responsiveness in toddlers. The results may inform Extension professionals providing mindfulness strategies for mothers of young children to improve feeding practices, ultimately reducing children's unhealthful eating behaviors.

Metabolic Dynamics Of Secondary Metabolites In Arabica Coffee (Coffea Arabica): From Biosynthesis To Post-Harvest Transformations, Kamilrashid Hadi Dwitama, Yudithia Maxiselly, Cucu Suherman, Santi Rosniawaty

Jurnal Kultivasi

Coffee (Coffea arabica) is a globally significant beverage whose sensory profile and physiological effects derive from a complex matrix of secondary metabolites. This review presents a comprehensive "lifecycle" perspective of three pivotal classes: the alkaloid caffeine, phenolic chlorogenic acids (CGA), and the diterpenoids cafestol and kahweol. Here, 'lifecycle' defines a metabolite's continuous biochemical trajectory, tracking its genetic origin and ecological function in the plant through structural modifications during fermentation, drying, storage, and roasting. These classes are highlighted because they serve as the primary drivers of bitterness, acidity, and health bioactivities with fundamentally distinct transformational pathways. Following a systematic methodology, this …

Evaluating The Potential Of Cajanus Cajan (L.) Millsp. Root To Improve Atopic Dermatitis With Different Anti-Inflammatory Models And Active Compounds, Shu-Er Yang, Xiang-Ming Cai, Yu-Wen Chu, Jen-Chieh Tsai, Mey-Fann Lee, Tuzz-Ying Song

Journal of Food and Drug Analysis

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent bacterial infections that cause pruritus, erythema, xerosis and thickening. Cajanus cajan root extract prepared with 95% ethanol (EECR95) has been shown to possess antioxidant, anti-inflammatory, and antibacterial properties in previous studies. This study aimed to evaluate EECR95’s ability to improve AD by inhibiting methicillin-resistant Staphylococcus aureus (MRSA) growth and reducing inflammation. This study found EECR95 effectively inhibits MRSA growth (IC₅₀ = 103.74 μg/mL) and reduces pro-inflammatory cytokine production in an MRSA-keratinocyte-macrophage model. LC/MS/MS analysis revealed the presence of active compounds- flavonoids, isoflavones, and flavonoid glycosides, highlighting EECR95's potential …

In Vitro Digestion Modifies Lepidium Meyenii Extract, Altering Its Major Glucosinolates, Lepidilines, Β-Carbolines, And Gut Bacterial Growth, Dominik Tarabasz, Ewa Baranowska-Wójcik, Paweł Szczeblewski, Tomasz Laskowski, Klaudia Gustaw, Marzena Furtak-Niczyporuk, Dominik Szwajgier, Rita Cristina Orihuela-Campos, Henry O. Meissner, Julia Borzyszkowska-Bukowska, Wirginia Kukula-Koch

Journal of Food and Drug Analysis

The tubers of Lepidium meyenii (commonly known as maca) have been used in the Andean cuisine for ages. The study aims to determine the behavior of the extract from the red phenotype of maca in the in vitro gastrointestinal tract model and also to define the overall impact of the extract on the microbiota. Glucosinolates, lepidilines, and a derivative of β-carboline alkaloid, i.e. 1-methyltetrahydro-β-5,6-hydride-carboline-3-carboxylic acid, as representatives of one of the main groups of metabolites were selected for the quantitative analysis after in vitro digestion at every stage of the digestion model. The results showed that lepidilines …

Bridging Animal Production And Human Nutrition: How Production Ecology Shapes The Nutritional Quality Of Terrestrial Animal Foods And Human Omega-3 Status, Joseph Vinod Varre

All Graduate Theses and Dissertations, Fall 2023 to Present

The question at the center of this dissertation is simple: does the way food is produced change the quality of the food itself in ways that matter for human health? Across a series of studies on bison meat, eggs, and human dietary intervention, the answer was yes. This work began with a broad look at the modern food system and the nutritional consequences of industrialized diets. In particular, it focused on the growing imbalance between omega-6 and omega-3 fatty acids in the Western diet. This balance matters because omega-3 fats support heart, brain, and immune health, and diets high in …

Youth Agricultural Engagement And Its Association With Dietary Diversity, Household Food Insecurity, And Nutritional Status In Southwest Nigeria, Sherif Olasoji

All Graduate Theses and Dissertations, Fall 2023 to Present

Youth remain underserved in nutrition research, policy, and programming despite being an integral part of the food systems. While the nutrition-sensitive agriculture framework has been established, there is limited evidence demonstrating how youth engagement in agriculture can serve as a pathway to improve nutritional outcomes. The study assessed youth agricultural engagement and its association with household dietary diversity, household food insecurity, and nutritional status in southwest Nigeria.

Using a cross-sectional design, data on socio-demographic characteristics, agricultural engagement, dietary diversity, household food insecurity, body mass index, and skin carotenoids were collected from 143 youth aged 15 to 35 from Ekiti, Osun, …

The Effects Of Psychological Stress On Gut Health In Mice Fed Either A Healthy Diet Or The Total Western Diet, David Keenan Thomas Prescott

All Graduate Theses and Dissertations, Fall 2023 to Present

The Total Western Diet (TWD), a rodent diet designed to model the typical American dietary pattern, has been shown to worsen inflammation and colitis severity in mice. Psychological stress has also been associated with increased intestinal inflammation, barrier dysfunction, and alterations to the gut microbiome. The goal of this study was to determine whether combining the TWD with psychological stress would further worsen colitis severity and alter the gut microbiome. To investigate this, mice were fed either a healthy control diet or the TWD and exposed to psychological stress using a social disruption stress model. Colitis was induced using established …