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Exercise Science

2013

Diabetes

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The Effect Of Whole Body Vibration On Skin Blood Flow And Nitric Oxide Production, Paula K. Johnson Jun 2013

The Effect Of Whole Body Vibration On Skin Blood Flow And Nitric Oxide Production, Paula K. Johnson

Theses and Dissertations

Background: Vascular dysfunction due to hyperglycemia in individuals with diabetes is a factor contributing to distal symmetric polyneuropathy (DSP). Reactive oxygen species (ROS) reduce the bioavailability of nitric oxide (NO), a powerful vasodilator, resulting in reduced circulation and nerve ischemia. Increases in blood NO concentrations and circulation have been attributed to whole body vibration (WBV). The purpose of this study was to the determine the effects of low frequency, low amplitude WBV on whole blood NO concentration and skin blood flow (SBF) in individuals with symptoms of DSP. Research Design and Methods: Ten subjects with diabetes and impaired sensory perception …