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Engineering

Anatoly Rozenfeld

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Full-Text Articles in Entire DC Network

Effect Of A Static Magnetic Field On Nanodosimetric Quantities In A Dna Volume, Peter Lazarakis, Marion U. Bug, Elisabetta Gargioni, Susanna Guatelli, Sabastien Incerti, Hans Rabus, Anatoly B. Rosenfeld Jun 2013

Effect Of A Static Magnetic Field On Nanodosimetric Quantities In A Dna Volume, Peter Lazarakis, Marion U. Bug, Elisabetta Gargioni, Susanna Guatelli, Sabastien Incerti, Hans Rabus, Anatoly B. Rosenfeld

Anatoly Rozenfeld

Abstract Purpose: With the advent of magnetic resonance imaging (MRI)-guided radiation therapy it is becoming increasingly important to consider the potential influence of a magnetic field on ionising radiation. This paper aims to study the effect of a magnetic field on the track structure of radiation to determine if the biological effectiveness may be altered. Methods: Using the Geant4-DNA (GEometry ANd Tracking 4) Monte Carlo simulation toolkit, nanodosimetric track structure parameters were calculated for electrons, protons and alpha particles moving in transverse magnetic fields up to 10 Tesla. Applying the model proposed by Garty et al., the track structure parameters …


Magneto-Radiotherapy: Effect Of Magnetic Field On Dose Distribution And Rbe, Heidi Nettelbeck, Anatoly B. Rosenfeld, George J. Takacs, Michael L. Lerch Jun 2013

Magneto-Radiotherapy: Effect Of Magnetic Field On Dose Distribution And Rbe, Heidi Nettelbeck, Anatoly B. Rosenfeld, George J. Takacs, Michael L. Lerch

Anatoly Rozenfeld

Magneto-radiotherapy is the application of magnetic fields during radiotherapy procedures. It aims to improve the quality of cancer treatment by altering the dose deposition of charged particles in the tissue volume being targeted. Our research has focused on applying the concept of magneto-radiotherapy to conventional linac treatment and MRT (Microbeam Radiation Therapy) oncology modalities.


Monte Carlo Study Of The Potential Reduction In Out-Of-Field Dose Using A Patient-Specific Aperture In Pencil Beam Scanning Proton Therapy, Stephen J. Dowdell, Benjamin Clasie, Nicolas Depauw, Peter E. Metcalfe, Anatoly B. Rosenfeld, Hanne M. Kooy, Jacob B. Flanz, Harald Paganetti Sep 2012

Monte Carlo Study Of The Potential Reduction In Out-Of-Field Dose Using A Patient-Specific Aperture In Pencil Beam Scanning Proton Therapy, Stephen J. Dowdell, Benjamin Clasie, Nicolas Depauw, Peter E. Metcalfe, Anatoly B. Rosenfeld, Hanne M. Kooy, Jacob B. Flanz, Harald Paganetti

Anatoly Rozenfeld

This study is aimed at identifying the potential benefits of using a patientspecific aperture in proton beam scanning. For this purpose, an accurate Monte Carlo model of the pencil beam scanning (PBS) proton therapy (PT) treatment head at Massachusetts General Hospital (MGH) was developed based on an existing model of the passive double-scattering (DS) system. The Monte Carlo code specifies the treatment head at MGH with sub-millimeter accuracy. The code was configured based on the results of experimental measurements performed at MGH. This model was then used to compare out-of-field doses in simulated DS treatments and PBS treatments. For the …