Digital Commons Network^™

Exploring Machine Learning Techniques To Improve Peptide Identification, Fawad Kirmani

Theses and Dissertations

The goal of this work is to improve proteotypic peptide prediction with lower pro- cessing time and better efficiency. Proteotypic peptides are the peptides in protein sequence that can be confidently observed by mass-spectrometry based proteomics. One of the widely used method for identifying peptides is tandem mass spectrometry (MS/MS). The peptides that need to be identified are compared with the accurate mass and elution time (AMT) tag database. The AMT tag database helps in reducing the processing time and increases the accuracy of the identified peptides. Prediction of proteotypic peptides has seen a rapid improvement in recent years for …

Inference Framework For Model Update And Development, Xiao Lin

Theses and Dissertations

Computational models play an important role in scientific discovery and engineering design. However, developing computational models is challenging, since the process always follows a path contaminated with errors and uncertainties. The uncertainties and errors inherent in computational models are the result of many factors, including experimental uncertainties, model structure inadequacies, uncertainties in model parameters and initial conditions, as well as errors due to numerical discretizations. To realize the full potential in applications it is critical to systematically and economically reduce the uncertainties inherent in all computational models.

Ontology-Guided Pre-Release Inference Disruption, Mark Stephen Daniels

Theses and Dissertations

We investigate privacy violations occurring when non-confidential patient data is combined with medical domain ontologies to disclose a patient’s protected health information (PHI). We propose a framework that detects privacy violations and eliminates undesired inferences. Our inference channel removal process is based on controlling the release of the data items that lead to undesired inferences. These data items are either blocked from release or generalized to eliminate the disclosure of the PHI. We show that our method is sound and complete. Soundness means the only inference paths generated logically follow from released data and corresponding domain knowledge. Completeness means we …

Bytecode-Based Multiple Condition Coverage: An Initial Investigation, Srujana Bollina

Theses and Dissertations

Masking occurs when one condition prevents another condition from influencing the output of a Boolean expression. Logic-based adequacy criteria such as Multiple Condition Coverage (MCC) are designed to overcome masking at the within-expression level, but can offer no guarantees about masking in subsequent expressions. As a result, a Boolean expression written as a single complex statement will yield test cases that are more likely to overcome masking than when the expression is written as series of simple statements. Many approaches to automated analysis and test case generation for Java systems operate not on the source code representation of code, but …

Tracking, Detection And Registration In Microscopy Material Images, Hongkai Yu

Theses and Dissertations

Fast and accurate characterization of fiber micro-structures plays a central role for material scientists to analyze physical properties of continuous fiber reinforced composite materials. In materials science, this is usually achieved by continuously crosssectioning a 3D material sample for a sequence of 2D microscopic images, followed by a fiber detection/tracking algorithm through the obtained image sequence.

To speed up this process and be able to handle larger-size material samples, we propose sparse sampling with larger inter-slice distance in cross sectioning and develop a new algorithm that can robustly track large-scale fibers from such a sparsely sampled image sequence. In particular, …

Ms. An (Meeting Students’ Academic Needs): A Socially Adaptive Robot Tutor For Student Engagement In Math Education, Karina Liles

Theses and Dissertations

This research presents a new, socially adaptive robot tutor, Ms. An (Meeting Students’ Academic Needs). The goal of this research was to use a decision tree model to develop a socially adaptive robot tutor that predicted and responded to student emotion and performance to actively engage students in mathematics education. The novelty of this multi-disciplinary project is the combination of the fields of HRI, AI, and education. In this study we 1) implemented a decision tree model to classify student emotion and performance for use in adaptive robot tutoring-an approach not applied to educational robotics; 2) presented an intuitive interface …

The Design, Development, And Evaluation Of A Usable And Privacy-Enhanced Telepresence Interface For Older Adults, Xian Wu

Theses and Dissertations

Maintaining health and wellness while aging-in-place independently is crucial for older adults. Telepresence technology can be potentially beneficial for this target population to stay socially connected. However, this technology is not specifically designed for older adults. For this target population to adopt such technology successfully, it is important to ensure that they do not experience usability barriers. This research uses HCI/HRI concepts and technology design principles for older adults to design, develop and test telepresence user interfaces (UI). This addresses the following research questions: 1): What are the essential usability and privacy-enhanced features needed to inform the design and development …

On The Security And Quality Of Wireless Communications In Outdoor Mobile Environment, Sharaf J. Malebary

Theses and Dissertations

The rapid advancement in wireless technology along with their low cost and ease of deployment have been attracting researchers academically and commercially. Researchers from private and public sectors are investing into enhancing the reliability, robustness, and security of radio frequency (RF) communications to accommodate the demand and enhance lifestyle. RF base communications -by nature- are slower and more exposed to attacks than a wired base (LAN). Deploying such networks in various cutting-edge mobile platforms (e.g. VANET, IoT, Autonomous robots) adds new challenges that impact the quality directly. Moreover, adopting such networks in public outdoor areas make them vulnerable to various …

Authenticating Users With 3d Passwords Captured By Motion Sensors, Jing Tian

Theses and Dissertations

Authentication plays a key role in securing various resources including corporate facilities or electronic assets. As the most used authentication scheme, knowledgebased authentication is easy to use but its security is bounded by how much a user can remember. Biometrics-based authentication requires no memorization but ‘resetting’ a biometric password may not always be possible. Thus, we propose study several behavioral biometrics (i.e., mid-air gestures) for authentication which does not have the same privacy or availability concerns as of physiological biometrics.

In this dissertation, we first propose a user-friendly authentication system Kin- Write that allows users to choose arbitrary, short and …