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Clinical Epidemiology

Loma Linda University Electronic Theses, Dissertations & Projects

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The Morbidity & Mortality Of Prevalent Heart Failure, Jennifer Kwon Dec 2012

The Morbidity & Mortality Of Prevalent Heart Failure, Jennifer Kwon

Loma Linda University Electronic Theses, Dissertations & Projects

The first study population included 292 unselected consecutive patients from the LLUMC heart failure clinic who were enrolled in the study from January to July 2006 and were followed up through the end of December 2010. The treatment policy at the clinic was to uptitrate dosages of beta-adrenergic blockade (β-blockers), angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) to the most tolerable levels in order to reach target dosages, as recommended by the Heart Failure Society of America (HFSA). Patients were classified into systolic heart failure (ejection fraction (EF) < 40%) or diastolic heart failure (EF≥40%). All dosages of β-blockers, ACEi and ARB were extracted through chart reviews and were used as the main predictors of the patients' survival. Results from analyses showed that reaching target dosages of β-blockers and ACEi/ARB may increase survival when compared to not reaching target among the systolic HF population (HRβ_biockers= 0.64, 95% CI 0.26-1.56 and HRACEi/ARB=0.50, …


Psychological Distress And Change In A Pediatric Obesity Population, Amy Rebecca Beck Dec 2008

Psychological Distress And Change In A Pediatric Obesity Population, Amy Rebecca Beck

Loma Linda University Electronic Theses, Dissertations & Projects

Pediatric overweight and obesity is a growing national epidemic with 15 percent of children ages 6-19 considered obese and at least 22 percent considered overweight. While there is considerable research pointing to contributing factors of obesity, there is a paucity of research which elucidates what contributes to successful intervention. Considering that by the year 2050, nearly 50 million Americans may be obese, understanding the factors delineating success of weight loss and prevention is a necessity. The purpose of this study was to utilize archival data from the LLU Growing Fit Program to evaluate the levels of psychological distress experienced by …


Secular Trends In Life Expectancy By Diet Status Among Never Smoking Seventh-Day Adventists, Noha Salim Daher Jun 2005

Secular Trends In Life Expectancy By Diet Status Among Never Smoking Seventh-Day Adventists, Noha Salim Daher

Loma Linda University Electronic Theses, Dissertations & Projects

To evaluate how life expectancy changed by age and secular time from 1960 through 1988, two cohort studies, the Adventist Mortality Study (AMS, 1960-1985, n = 27,530) and the Adventist Health Study (AHS, 1976-1988, n = 34,192) were combined. The life expectancy of omnivores was compared to vegetarians separately in never-smoking males and females for all-cause mortality, and where the cause of death was cardiovascular disease or all site-cancer. Life expectancies were calculated for subjects who had survived to ages 30, 50, 70, and 80 during six calendar periods: 1960- 1964, 1965-1969, 1970-1974, 1975-1979, 1980-1984, and 1985-1988. Ten-year calendar periods …


The Association Of Fluid Intake With Total Natural-Cause Mortality, Coronary Heart Disease And Fatal Stroke, Jacqueline Chung Lun Chan Jan 1999

The Association Of Fluid Intake With Total Natural-Cause Mortality, Coronary Heart Disease And Fatal Stroke, Jacqueline Chung Lun Chan

Loma Linda University Electronic Theses, Dissertations & Projects

Hypohydration may be more widespread than realized since it does not always arouse a sense of thirst. When thirst is felt, it is often ignored, or satisfied before euhydration is achieved. There is growing evidence indicating that hypohydration contributes to acute and chronic illnesses, and to rheological factors associated with coronary heart disease (CHD) and stroke. Therefore the relationship of fluid intake with risk of total natural-cause mortality, CHD and stroke death was examined using data on 34,192 white, non-Hispanic participants in the Adventist Health Study.

Among the 27,342 reporting no CHD, stroke or diabetes at baseline, during six years …


The Effect Of Electroshock On The Passage Of Bacteria From A Contaminated Transducer Past A Protective Membrane Into A Disposable Chamber Dome, Patricia K. Taylor Pothier Jun 1984

The Effect Of Electroshock On The Passage Of Bacteria From A Contaminated Transducer Past A Protective Membrane Into A Disposable Chamber Dome, Patricia K. Taylor Pothier

Loma Linda University Electronic Theses, Dissertations & Projects

Infection related to use of Intra-arterial Hemodynamic Monitoring Devices is a serious complication. In an attempt to decrease the risk of infection presterilized chamber domes were developed to isolate the patient vascular system from the pressure transducer. Users were informed by manufacturers of the domes that routine decontamination of transducer heads was not necessary. Since the development of these disposable chamber domes infection outbreaks have continued to occur. Epidemiological investigation has implicated contact transmission of bacteria due to poor handling techniques in some outbreaks. However, in other outbreaks the source of the epidemic was found to be contaminated transducer heads …


Contamination Of Stuffed Cloth Toys On A Pediatric Unit, Virginia Lois Fowler, Dynnette Nelson Hart May 1968

Contamination Of Stuffed Cloth Toys On A Pediatric Unit, Virginia Lois Fowler, Dynnette Nelson Hart

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of the study was to determine if cloth stuffed toys used by children in the pediatric unit of Loma Linda University Hospital carry microbacterial pathogens that are the same type as those pathogens found in the throat of the child using the toy. A second purpose was to determine how long the selected pathogens, Staphylococcus aureus, Streptococcus pyogenes, and Diplococcus pneumonia, survive on the same cloth toys as used in the selected hospital. Throat cultures were taken of twenty-four patients and each patient was given a cloth stuffed toy selected to be studied. Cultures of the toys were …


A Study Of Door Pulls On Isolation Carts In A General Hospital For Evidence Of Contamination, Mary Alice Harper Jun 1964

A Study Of Door Pulls On Isolation Carts In A General Hospital For Evidence Of Contamination, Mary Alice Harper

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of the study was to find out if isolation carts were serving as a means of cross infection. Literature pertaining to sources of possible contamination on hospital units written in the past five years were reviewed.

Using the descriptive survey as the method of study, effort was made to find out if isolation carts were a means of cross infection on the hospital unit. Two laboratory cultures were obtained from both door pulls on all isolation carts used by nursing units. This was done over a three month period from December 12, 1963 to March 11, 1964. The …