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Integrative Analysis Of Prognosis Data On Multiple Cancer Subtypes, Shuangge Ma
Integrative Analysis Of Prognosis Data On Multiple Cancer Subtypes, Shuangge Ma
Shuangge Ma
In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is diverse. Examining similarity and difference in the genetic basis of multiple subtypes of the same cancer can lead to a better understanding of their connections and distinctions. Classic meta-analysis methods analyze each subtype separately and then compare analysis results across subtypes. Integrative analysis methods, in contrast, analyze the raw data on multiple subtypes simultaneously and can outperform meta-analysis methods. In this study, prognosis data on multiple subtypes of the same cancer are analyzed. An AFT (accelerated failure time) model is adopted to describe …
Identification Of Cancer-Associated Gene Pathways From Analysis Of Expression Data, Shuangge Ma
Identification Of Cancer-Associated Gene Pathways From Analysis Of Expression Data, Shuangge Ma
Shuangge Ma
No abstract provided.
Lecture 5, Shuangge Ma
Final Project, Shuangge Ma
Lecture 4, Shuangge Ma
Lecture 4, Shuangge Ma
Computer Intensive Methods Lecture 13, Shuangge Ma
Final Project (Description), Shuangge Ma
Final Project (Data), Shuangge Ma
Lecture 3, Shuangge Ma
Lecture 2, Shuangge Ma
Reference: Multiple Imputation, Shuangge Ma
Reference: Weighted Bootstrap, Shuangge Ma
Computer Intensive Methods Lecture 9, Shuangge Ma
Computer Intensive Methods Lecture 8, Shuangge Ma
Reference: Counter Examples [Bootstrap], Shuangge Ma
Reference: Counter Examples [Bootstrap], Shuangge Ma
Shuangge Ma
No abstract provided.
Computer Intensive Methods Lecture 7 (Lab 2), Shuangge Ma
Computer Intensive Methods Lecture 7 (Lab 2), Shuangge Ma
Shuangge Ma
No abstract provided.
Computer Intensive Methods Lecture 6, Shuangge Ma
Reference: Block Jackknife, Shuangge Ma
Computer Intensive Methods Lecture 5, Shuangge Ma
Reading: Simulate Multivariate Distribution, Shuangge Ma
Reading: Simulate Multivariate Distribution, Shuangge Ma
Shuangge Ma
No abstract provided.
Computer Intensive Methods Lecture 4, Shuangge Ma
Computer Intensive Methods Lecture 3 (Lab 1), Shuangge Ma
Computer Intensive Methods Lecture 3 (Lab 1), Shuangge Ma
Shuangge Ma
No abstract provided.
Computer Intensive Methods Lecture 2, Shuangge Ma
Computer Intensive Methods Lecture 1, Shuangge Ma
Detection Of Gene Pathways With Predictive Power For Breast Cancer Prognosis, Shuangge Ma
Detection Of Gene Pathways With Predictive Power For Breast Cancer Prognosis, Shuangge Ma
Shuangge Ma
Prognosis of breast cancer is of great scientific and practical interest. Biomedical studies suggest that clinical and environmental risk factors do not have satisfactory predictive power for prognosis. Multiple gene profiling studies have been conducted, searching for predictive genomic measurements. Genes have the inherent pathway structure, where pathways are composed of multiple genes with similar biological functions. The goal of this study is to identify gene pathways with predictive power for breast cancer prognosis. Although multiple pathway analysis methods are available, they have certain drawbacks and are not suitable for the proposed analysis. In this article, we develop a new …