Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Freshwater (4)
- Nabokov (4)
- Bioenergy (3)
- Cellulosic (3)
- Evolution (3)
-
- Lake Michigan (3)
- Metagenomics (3)
- Switchgrass (3)
- Uncertainty (3)
- Bacteria (2)
- Biology (2)
- Course Syllabus (2)
- Horizontal gene transfer (2)
- Microbial community (2)
- Neisseria (2)
- Pathogen-host DNA transfer (2)
- Pathogenicity islands (2)
- RNA-seq (2)
- Abundence (1)
- Action Potential (1)
- Adaptability (1)
- Adaptation (1)
- Algae (1)
- Alice (1)
- American goldfinch (1)
- Anthropogenic (1)
- Apoidea (1)
- Automatic graph layout (1)
- Autonomy (1)
- Bacillariophyta (1)
- Publication
-
- Catherine Putonti (15)
- James Cheverud (7)
- Patricia Parker (5)
- Victor Fet (4)
- Gail Gasparich (3)
-
- Leon Hardy (3)
- Robert Ricklefs (3)
- Ben G. Fitzpatrick (2)
- David Wilson (2)
- Erika Gibb (2)
- Howard Laten (2)
- Lon Chubiz (2)
- Mark E. Eberle (2)
- Oliver Kerscher (2)
- Ray Enke Ph.D. (2)
- Beth Reinke (1)
- Bridget Vincent (1)
- Carrie Buo (1)
- Christian Nawroth, Ph.D. (1)
- Christopher Spilling (1)
- Cynthia Dupureur (1)
- Eric Forgoston (1)
- F. Robin O’Keefe (1)
- Foster Levy (1)
- Frank Peiris (1)
- Frank S. Gilliam (1)
- Jason Brown (1)
- Jibin Zhang (1)
- Jonathan McMurry (1)
- Katherine Campbell, PhD (1)
Articles 1 - 30 of 83
Full-Text Articles in Entire DC Network
Emma Lucy Braun's Forest Plots In Eastern North America, Robert E. Ricklefs
Emma Lucy Braun's Forest Plots In Eastern North America, Robert E. Ricklefs
Robert Ricklefs
No abstract provided.
Mechanical Test Methods For Assessing Porcine Carotid And Uterine Artery Burst Pressure Following Ex Vivo Ultrasonic Ligature Seal And Transection, Carissa M. Krane, Margaret Pinnell, Courtney Gardner, Mercedes Thompson, James Coleman, Robert Wilkens
Mechanical Test Methods For Assessing Porcine Carotid And Uterine Artery Burst Pressure Following Ex Vivo Ultrasonic Ligature Seal And Transection, Carissa M. Krane, Margaret Pinnell, Courtney Gardner, Mercedes Thompson, James Coleman, Robert Wilkens
Robert J. Wilkens
A test method was developed to identify those variables important for assessing the performance of ultrasonic surgical devices in ex vivo ligature sealing of porcine carotid and uterine arteries. Ruggedness testing using a small sample size in pilot experiments was conducted using a newly developed test method in an effort to assess the usefulness of this methodology and to identify test variables that might warrant further testing. The development of this test method included the use of a custom-designed prototypic tension device for load-controlled ex vivo vessel stretching during saline perfusion and subsequent seal and transection of porcine arteries with …
A Survey Of Lepidopteran Diversity And Abundance At Longwood University’S Lancer Park, Victoria Acosta, Sujan Henkanaththegedara
A Survey Of Lepidopteran Diversity And Abundance At Longwood University’S Lancer Park, Victoria Acosta, Sujan Henkanaththegedara
Victoria Acosta
Recent Diatoms Reported From The Central United States: Register Of Taxa And Synonyms, Mark E. Eberle
Recent Diatoms Reported From The Central United States: Register Of Taxa And Synonyms, Mark E. Eberle
Mark E. Eberle
This list of diatoms summarizes information for more than 1000 taxa and synonyms reported in published accounts of collections made in the central United States, principally within the states of Kansas, Nebraska, and Oklahoma, but also including adjacent areas in eastern Colorado and western Missouri. The objective was to provide people working on diatom projects in this region with a base reference to help them assess the results of their research. Records from Master’s theses and references focused on fossil diatoms were not incorporated into this list. Specimens were not examined, so taxa presented here are those reported in the …
Freshwater Mussels Of Kansas: Register Of Taxa, Synonyms, And Assumed Misidentifications, Mark E. Eberle
Freshwater Mussels Of Kansas: Register Of Taxa, Synonyms, And Assumed Misidentifications, Mark E. Eberle
Mark E. Eberle
The literature on freshwater mussels (Mollusca: Margaritiferidae and Unionidae) of Kansas includes a collection of names of species and subspecies that makes it difficult for even experienced malacologists to decipher which taxa actually were collected. Compounding this problem is the absence of voucher specimens for some of the studies conducted in the state. This list was compiled to aid those who are conducting research and want to assess their results with reference to the earlier accounts. The alphabetical list of valid taxa, synonyms, and assumed misidentifications of freshwater mussels of Kansas is drawn from the literature and not an examination …
Biology 141 Principles Of Biology I Fall 2015, David M. Wilson, Bryab Krall
Biology 141 Principles Of Biology I Fall 2015, David M. Wilson, Bryab Krall
David Wilson
No abstract provided.
Biology 141 Principles Of Biology I Spring 2015, Scott Siechen, David M. Wilson
Biology 141 Principles Of Biology I Spring 2015, Scott Siechen, David M. Wilson
David Wilson
No abstract provided.
The Genetic Architecture Of Fluctuating Asymmetry Of Mandible Size And Shape In A Population Of Mice: Another Look, James M. Cheverud, Larry J. Leamy, Christian Peter Klingenberg, Emma Sherratt, Jason B. Wolf
The Genetic Architecture Of Fluctuating Asymmetry Of Mandible Size And Shape In A Population Of Mice: Another Look, James M. Cheverud, Larry J. Leamy, Christian Peter Klingenberg, Emma Sherratt, Jason B. Wolf
James Cheverud
Fluctuating asymmetry (FA), typically measured by variation in the differences between right and left sides of bilateral traits, is commonly used to assess developmental instability (DI) in populations. A previous quantitative trait locus (QTL) investigation using an F2 intercross mouse population found little evidence of individual loci affecting FA in mandible size, but an abundance of epistatic interactions between loci. Here we extend this work by testing whether these patterns replicate in an F3 population derived from the same intercross. Using a large number of molecular markers genotyped in over 1200 mice, we uncovered significant interactions between loci (QTLs) affecting …
Using Whole-Genome Sequences Of The Lg/J And Sm/J Inbred Mouse Strains To Prioritize Quantitative Trait Genes And Nucleotides, Igor Nikolskiy, Donald F. Conrad, Sung Chun, Justin C. Fay, James M. Cheverud, Heather A. Lawson
Using Whole-Genome Sequences Of The Lg/J And Sm/J Inbred Mouse Strains To Prioritize Quantitative Trait Genes And Nucleotides, Igor Nikolskiy, Donald F. Conrad, Sung Chun, Justin C. Fay, James M. Cheverud, Heather A. Lawson
James Cheverud
Background The laboratory mouse is the most commonly used model for studying variation in complex traits relevant to human disease. Here we present the whole-genome sequences of two inbred strains, LG/J and SM/J, which are frequently used to study variation in complex traits as diverse as aging, bone-growth, adiposity, maternal behavior, and methamphetamine sensitivity. Results We identified small nucleotide variants (SNVs) and structural variants (SVs) in the LG/J and SM/J strains relative to the reference genome and discovered novel variants in these two strains by comparing their sequences to other mouse genomes. We find that 39% of the LG/J and …
The Effect Of Dietary Fat Intake On Hepatic Gene Expression In Lg/J And Sm/J Mice, Charlyn G. Partridge, Gloria L. Fawcett, Bing Wang, Clay F. Semenkovich, James M. Cheverud
The Effect Of Dietary Fat Intake On Hepatic Gene Expression In Lg/J And Sm/J Mice, Charlyn G. Partridge, Gloria L. Fawcett, Bing Wang, Clay F. Semenkovich, James M. Cheverud
James Cheverud
Background The liver plays a major role in regulating metabolic homeostasis and is vital for nutrient metabolism. Identifying the genetic factors regulating these processes could lead to a greater understanding of how liver function responds to a high-fat diet and how that response may influence susceptibilities to obesity and metabolic syndrome. In this study we examine differences in hepatic gene expression between the LG/J and SM/J inbred mouse strains and how gene expression in these strains is affected by high-fat diet. LG/J and SM/J are known to differ in their responses to a high-fat diet for a variety of obesity- …
The Genetic Basis Of Baculum Size And Shape Variation In Mice, Nicholas G. Schultz, Jesse Ingels, Andrew Hillhouse, Keegan Wardwell, Peter L. Chang, James M. Cheverud, Cathleen Lutz, Lu Lu, Robert W. Williams, Matthew D. Dean
The Genetic Basis Of Baculum Size And Shape Variation In Mice, Nicholas G. Schultz, Jesse Ingels, Andrew Hillhouse, Keegan Wardwell, Peter L. Chang, James M. Cheverud, Cathleen Lutz, Lu Lu, Robert W. Williams, Matthew D. Dean
James Cheverud
The rapid divergence of male genitalia is a preeminent evolutionary pattern. This rapid divergence is especially striking in the baculum, a bone that occurs in the penis of many mammalian species. Closely related species often display diverse baculum morphology where no other morphological differences can be discerned. While this fundamental pattern of evolution has been appreciated at the level of gross morphology, nearly nothing is known about the genetic basis of size and shape divergence. Quantifying the genetic basis of baculum size and shape variation has been difficult because these structures generally lack obvious landmarks, so comparing them in three …
Identification Of Eqtls For Hepatic Xbp1s And Socs3 Gene Expression In Mice Fed A High-Fat, High Caloric Diet, James M. Cheverud, Sarina Pasricha, Jane Kenney-Hunt, Kristy Anderson, Naderah Jafari, Rabea A. Hall, Frank Lammert, Richard M. Green
Identification Of Eqtls For Hepatic Xbp1s And Socs3 Gene Expression In Mice Fed A High-Fat, High Caloric Diet, James M. Cheverud, Sarina Pasricha, Jane Kenney-Hunt, Kristy Anderson, Naderah Jafari, Rabea A. Hall, Frank Lammert, Richard M. Green
James Cheverud
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent form of human hepatic disease and feeding mice a high-fat, high-caloric (HFHC) diet is a standard model of NAFLD. To better understand the genetic basis of NAFLD, we conducted an expression quantitative trait locus (eQTL) analysis of mice fed a HFHC diet. Two-hundred sixty-five (A/J × C57BL/6J) F2 male mice were fed a HFHC diet for 8 wk. eQTL analysis was utilized to identify genomic regions that regulate hepatic gene expression of Xbp1s and Socs3. We identified two overlapping loci for Xbp1s and Socs3 on Chr 1 (164.0–185.4 Mb and 174.4–190.5 …
Characterizing The Evolutionary Path(S) To Early Homo, Lauren Schroeder, Charles C. Roseman, James M. Cheverud, Rebecca R. Ackermann
Characterizing The Evolutionary Path(S) To Early Homo, Lauren Schroeder, Charles C. Roseman, James M. Cheverud, Rebecca R. Ackermann
James Cheverud
Numerous studies suggest that the transition from Australopithecus to Homo was characterized by evolutionary innovation, resulting in the emergence and coexistence of a diversity of forms. However, the evolutionary processes necessary to drive such a transition have not been examined. Here, we apply statistical tests developed from quantitative evolutionary theory to assess whether morphological differences among late australopith and early Homo species in Africa have been shaped by natural selection. Where selection is demonstrated, we identify aspects of morphology that were most likely under selective pressure, and determine the nature (type, rate) of that selection. Results demonstrate that selection must …
Genomic Correlates Of Relationship Qtl Involved In Fore- Versus Hind Limb Divergence In Mice, Mihaela Palicev, Gunter P. Wagner, James P. Noonan, Benedikt Hallgrimsson, James M. Cheverud
Genomic Correlates Of Relationship Qtl Involved In Fore- Versus Hind Limb Divergence In Mice, Mihaela Palicev, Gunter P. Wagner, James P. Noonan, Benedikt Hallgrimsson, James M. Cheverud
James Cheverud
Divergence of serially homologous elements of organisms is a common evolutionary pattern contributing to increased phenotypic complexity. Here, we study the genomic intervals affecting the variational independence of fore- and hind limb traits within an experimental mouse population. We use an advanced intercross of inbred mouse strains to map the loci associated with the degree of autonomy between fore- and hind limb long bone lengths (loci affecting the relationship between traits, relationship quantitative trait loci [rQTL]). These loci have been proposed to interact locally with the products of pleiotropic genes, thereby freeing the local trait from the variational constraint due …
Diaspora, A Large Family Of Ty3-Gypsy Retrotransposons In Glycine Max, Is An Envelope-Less Member Of An Endogenous Plant Retrovirus Lineage, Sho T. Yano, Bahman Panbehi, Arpita Das, Howard M. Laten
Diaspora, A Large Family Of Ty3-Gypsy Retrotransposons In Glycine Max, Is An Envelope-Less Member Of An Endogenous Plant Retrovirus Lineage, Sho T. Yano, Bahman Panbehi, Arpita Das, Howard M. Laten
Howard Laten
Background The chromosomes of higher plants are littered with retrotransposons that, in many cases, constitute as much as 80% of plant genomes. Long terminal repeat retrotransposons have been especially successful colonizers of the chromosomes of higher plants and examinations of their function, evolution, and dispersal are essential to understanding the evolution of eukaryotic genomes. In soybean, several families of retrotransposons have been identified, including at least two that, by virtue of the presence of an envelope-like gene, may constitute endogenous retroviruses. However, most elements are highly degenerate and are often sequestered in regions of the genome that sequencing projects initially …
Computational And Experimental Analyses Of Retrotransposon-Associated Minisatellite Dnas In The Soybean Genome, Lauren S. Mogil, Kamil Slowikowski, Howard M. Laten
Computational And Experimental Analyses Of Retrotransposon-Associated Minisatellite Dnas In The Soybean Genome, Lauren S. Mogil, Kamil Slowikowski, Howard M. Laten
Howard Laten
BACKGROUND: Retrotransposons are mobile DNA elements that spread through genomes via the action of element-encoded reverse transcriptases. They are ubiquitous constituents of most eukaryotic genomes, especially those of higher plants. The pericentromeric regions of soybean (Glycine max) chromosomes contain >3,200 intact copies of the Gmr9/GmOgre retrotransposon. Between the 3' end of the coding region and the long terminal repeat, this retrotransposon family contains a polymorphic minisatellite region composed of five distinct, interleaved minisatellite families. To better understand the possible role and origin of retrotransposon-associated minisatellites, a computational project to map and physically characterize all members of these families in the …
Miip: The Monomer Identification And Isolation Program, Christopher Bun, William Ziccardi, Jeffrey Doering, Catherine Putonti
Miip: The Monomer Identification And Isolation Program, Christopher Bun, William Ziccardi, Jeffrey Doering, Catherine Putonti
Catherine Putonti
Repetitive elements within genomic DNA are both functionally and evolutionarily informative. Discovering these sequences ab initio is computationally challenging, compounded by the fact that selection on these repeats is often relaxed; thus sequence identity between repetitive elements can vary significantly. Here we present a new application, the Monomer Identification and Isolation Program (MiIP), which provides functionality to both search for a particular repeat as well as discover repetitive elements within a larger genomic sequence. To compare MiIP’s performance with other repeat detection tools, analysis was conducted for synthetic sequences as well as several α21-II clones and HC21 BAC sequences. The …
Survey Of Microbial Populations Within Lake Michigan Nearshore Waters At Two Chicago Public Beaches, Kema Malki, Katherine Bruder, Catherine Putonti
Survey Of Microbial Populations Within Lake Michigan Nearshore Waters At Two Chicago Public Beaches, Kema Malki, Katherine Bruder, Catherine Putonti
Catherine Putonti
Lake Michigan is a critical resource for the residents of Chicago, providing drinking water to its 9+ million area residents. Along Chicago׳s 26 miles of public beaches the populous urban environment and this freshwater environment meet. While city-led monitoring initiatives investigate pathogenic bacteria in these nearshore waters, very little is known about other microbial species present. We collected surface water samples from two Chicago public beaches – Montrose Beach and 57th Street Beach – every ten days from June 5 through August 4, 2013 as well as once in early Fall (October 4, 2013). Sixteen bacterial communities in total were …
Survey Of Viral Populations Within Lake Michigan Nearshore Waters At Four Chicago Area Beaches, Emily Sible, Alexandria Cooper, Kema Malki, Katherine Bruder, Siobhan C. Watkins, Yuriy Fofanov, Catherine Putonti
Survey Of Viral Populations Within Lake Michigan Nearshore Waters At Four Chicago Area Beaches, Emily Sible, Alexandria Cooper, Kema Malki, Katherine Bruder, Siobhan C. Watkins, Yuriy Fofanov, Catherine Putonti
Catherine Putonti
In comparison to the oceans, freshwater environments represent a more diverse community of microorganisms, exhibiting comparatively high levels of variability both temporally and spatially Maranger and Bird, Microb. Ecol. 31 (1996) 141–151. This level of variability is likely to extend to the world of viruses as well, in particular bacteria-infecting viruses (bacteriophages). Phages are known to influence bacterial diversity, and therefore key processes, in environmental niches across the globe Clokie et al., Bacteriophage 1 (2011) 31–45; Jacquet et al., Adv. Ocean Limn. 1 (2010) 97–141; Wilhelm and Suttle, Bioscience 49 (1999) 781–788; Bratback et al., Microb. Ecol. 28 (1994) 209–221. …
Where Does Neisseria Acquire Foreign Dna From: An Examination Of The Source Of Genomic And Pathogenic Islands And The Evolution Of The Neisseria Genus, Catherine Putonti, Bogdan Nowicki, Michael Shaffer, Yuriy Fofanov, Stella Nowicki
Where Does Neisseria Acquire Foreign Dna From: An Examination Of The Source Of Genomic And Pathogenic Islands And The Evolution Of The Neisseria Genus, Catherine Putonti, Bogdan Nowicki, Michael Shaffer, Yuriy Fofanov, Stella Nowicki
Catherine Putonti
Background Pathogenicity islands (PAIs) or genomic islands (GEIs) are considered to be the result of a recent horizontal transfer. Detecting PAIs/GEIs as well as their putative source can provide insight into the organism’s pathogenicity within its host. Previously we introduced a tool called S-plot which provides a visual representation of the variation in compositional properties across and between genomic sequences. Utilizing S-plot and new functionality developed here, we examined 18 publicly availableNeisseria genomes, including strains of both pathogenic and non-pathogenic species, in order to identify regions of unusual compositional properties (RUCPs) using both a sliding window as well as a …
Pcr Detection Of Nearly Any Dengue Virus Strain Using A Highly Sensitive Primer ‘Cocktail’, Charul Gijavanekal, Maria Anez-Lingerfelt, Chen Feng, Catherine Putonti, George E. Fox, Aniko Sabo, Yuriy Fofanov, Richard C. Wilson
Pcr Detection Of Nearly Any Dengue Virus Strain Using A Highly Sensitive Primer ‘Cocktail’, Charul Gijavanekal, Maria Anez-Lingerfelt, Chen Feng, Catherine Putonti, George E. Fox, Aniko Sabo, Yuriy Fofanov, Richard C. Wilson
Catherine Putonti
PCR detection of viral pathogens is extremely useful, but suffers from thechallenge of detecting the many variant strains of a given virus that ariseover time. Here, we report the computational derivation and initial experi-mental testing of a combination of 10 PCR primers to be used in a singlehigh-sensitivity mixed PCR reaction for the detection of dengue virus. Pri-mer sequences were computed such that their probability of misprimingwith human DNA is extremely low. A ‘cocktail’ of 10 primers was shownexperimentally to be able to detect cDNA clones representing the four sero-types and dengue virus RNA spiked into total human whole blood …
Mechanisms Responsible For A Φx174 Mutant's Ability To Infect Escherichia Coli By Phosphorylation, Jennifer Cox, Catherine Putonti
Mechanisms Responsible For A Φx174 Mutant's Ability To Infect Escherichia Coli By Phosphorylation, Jennifer Cox, Catherine Putonti
Catherine Putonti
The ability for a virus to expand its host range is dependent upon a successful mode of viral entry. As such, the host range of the well-studied ΦX174 bacteriophage is dictated by the presence of a particular lipopolysaccharide (LPS) on the bacterial surface. The mutant ΦX174 strain JACS-K, unlike its ancestor, is capable of infecting both its native host Escherichia coli C and E. coli K-12, which does not have the necessary LPS. The conversion of an alanine to a very reactive threonine on its virion surface was found to be responsible for the strain's expanded host range.
From Where Does Neisseria Acquire Foreign Dna: An Examination Of The Source Of Genomic And Pathogenic Islands And The Evolution Of The Neisseria Genus, Catherine Putonti, Bogdan Nowicki, Michael Shaffer, Yuriy Fofanov, Stella Nowicki
From Where Does Neisseria Acquire Foreign Dna: An Examination Of The Source Of Genomic And Pathogenic Islands And The Evolution Of The Neisseria Genus, Catherine Putonti, Bogdan Nowicki, Michael Shaffer, Yuriy Fofanov, Stella Nowicki
Catherine Putonti
Background Pathogenicity islands (PAIs) or genomic islands (GEIs) are considered to be the result of a recent horizontal transfer. Detecting PAIs/GEIs as well as their putative source can provide insight into the organism’s pathogenicity within its host. Previously we introduced a tool called S-plot which provides a visual representation of the variation in compositional properties across and between genomic sequences. Utilizing S-plot and new functionality developed here, we examined 18 publicly available Neisseria genomes, including strains of both pathogenic and non-pathogenic species, in order to identify regions of unusual compositional properties (RUCPs) using both a sliding window as well as …
Cbdb: The Codon Bias Database, Adam Hilterbrand, Joseph Saelens, Catherine Putonti
Cbdb: The Codon Bias Database, Adam Hilterbrand, Joseph Saelens, Catherine Putonti
Catherine Putonti
Background In many genomes, a clear preference in the usage of particular codons exists. The mechanisms that induce codon biases remain an open question; studies have attributed codon usage to translational selection, mutational bias and drift. Furthermore, correlations between codon usage within host genomes and their viral pathogens have been observed for a myriad of host-virus systems. As such, numerous studies have investigated codon usage and codon bias in an effort to better understand how species evolve. Numerous metrics have been developed to identify biases in codon usage. In addition, a few data repositories of codon bias data are available, …
Assessment Of A Metaviromic Dataset Generated From Nearshore Lake Michigan, Siobhan C. Watkins, Neil Kuehnle, C Anthony Ruggeri, Kema Malki, Katherine Bruder, Jinan Elayyan, Kristina Damisch, Naushin Vahora, Paul O'Malley, Brianne Ruggles-Sage, Zachary Romer, Catherine Putonti
Assessment Of A Metaviromic Dataset Generated From Nearshore Lake Michigan, Siobhan C. Watkins, Neil Kuehnle, C Anthony Ruggeri, Kema Malki, Katherine Bruder, Jinan Elayyan, Kristina Damisch, Naushin Vahora, Paul O'Malley, Brianne Ruggles-Sage, Zachary Romer, Catherine Putonti
Catherine Putonti
Bacteriophages are powerful ecosystem engineers. They drive bacterial mortality rates and genetic diversity, and affect microbially mediated biogeochemical processes on a global scale. This has been demonstrated in marine environments; however, phage communities have been less studied in freshwaters, despite representing a potentially more diverse environment. Lake Michigan is one of the largest bodies of freshwater on the planet, yet to date the diversity of its phages has yet to be examined. Here, we present a composite survey of viral ecology in the nearshore waters of Lake Michigan. Sequence analysis was performed using a web server previously used to analyse …
Comparison Of The Compositional Proclivities Of The Complete Genomes Of Plasmodium Falciparum And Human, April Williams, Yuriy Fofanov, Catherine Putonti
Comparison Of The Compositional Proclivities Of The Complete Genomes Of Plasmodium Falciparum And Human, April Williams, Yuriy Fofanov, Catherine Putonti
Catherine Putonti
Pathogens and hosts have a dynamic relationship, one that is ever changing at the molecular level - the pathogen influencing the evolutionary path of the host and the host influencing the evolutionary path of the pathogen. The pathogen’s adaptation to a particular host could serve several purposes, e.g. to mimic the host to avoid detection, to take advantage of the host’s cellular machinery, to increase virulence, etc. Recognizing these adaptations is far from trivial, particularly when the size of the pathogen’s and host’s genomes differ by orders of magnitudes. Novel algorithms and data structures have been developed in our laboratory …
Evolution Of The Sequence Composition Of Flaviviruses, Alyxandria M. Schubert, Catherine Putonti
Evolution Of The Sequence Composition Of Flaviviruses, Alyxandria M. Schubert, Catherine Putonti
Catherine Putonti
The adaption of pathogens to their host(s) is a major factor in the emergence of infectious disease and the persistent survival of many of the infectious diseases within the population. Since many of the smaller viral pathogens are entirely dependent upon host machinery, it has been postulated that they are under selection for a composition similar to that of their host. Analyses of sequence composition have been conducted for numerous small viral species including the Flavivirus genus. Examination of the species within this particular genus that infect vertebrate hosts revealed that sequence composition proclivities do not correspond with vector transmission …
Adaptive Evolution And Inherent Tolerance To Extreme Thermal Environments, Jennifer Cox, Alyxandria Schubert, Michael Travisano, Catherine Putonti
Adaptive Evolution And Inherent Tolerance To Extreme Thermal Environments, Jennifer Cox, Alyxandria Schubert, Michael Travisano, Catherine Putonti
Catherine Putonti
Background When introduced to novel environments, the ability for a species to survive and rapidly proliferate corresponds with its adaptive potential. Of the many factors that can yield an environment inhospitable to foreign species, phenotypic response to variation in the thermal climate has been observed within a wide variety of species. Experimental evolution studies using bacteriophage model systems have been able to elucidate mutations, which may correspond with the ability of phage to survive modest increases/decreases in the temperature of their environment. Results Phage ΦX174 was subjected to both elevated (50°C) and extreme (70°C+) temperatures for anywhere from a few …
Improved Detection Of Bartonella Dna In Mammalian Hosts And Arthropod Vectors By Real-Time Pcr Using The Nadh Dehydrogenase Gamma Subunit (Nuog), James M. Colborn, Michael Y. Kosoy, Vladimir L. Motin, Maxim V. Telepnev, Gustavo Valbuena, Khin S. Myint, Yuri Fofanov, Catherine Putonti, Chen Feng, Leonard Peruski
Improved Detection Of Bartonella Dna In Mammalian Hosts And Arthropod Vectors By Real-Time Pcr Using The Nadh Dehydrogenase Gamma Subunit (Nuog), James M. Colborn, Michael Y. Kosoy, Vladimir L. Motin, Maxim V. Telepnev, Gustavo Valbuena, Khin S. Myint, Yuri Fofanov, Catherine Putonti, Chen Feng, Leonard Peruski
Catherine Putonti
We used a whole-genome scanning technique to identify the NADH dehydrogenase gamma subunit (nuoG) primer set that is sensitive and specific enough to detect a diverse number of Bartonella species in a wide range of environmental samples yet maintains minimal cross-reactivity to mammalian host and arthropod vector organisms.
Assessment Of Microbial Populations Within Chicago Area Nearshore Waters And Interfaces With River Systems, Emily Sible, Alexandria Cooper, Kema Malki, Katherine Bruder, Thomas Hatzopoulos, Siobhan C. Watkins, Catherine Putonti
Assessment Of Microbial Populations Within Chicago Area Nearshore Waters And Interfaces With River Systems, Emily Sible, Alexandria Cooper, Kema Malki, Katherine Bruder, Thomas Hatzopoulos, Siobhan C. Watkins, Catherine Putonti
Catherine Putonti
The Chicago area locks separate and control water flow between the freshwaters of Lake Michigan and the network of Illinois waterways. Under extreme storm conditions, however, the locks are opened and storm waters, untreated waste, and runoff are released directly into the lake. These combined sewer overflow (CSO) events introduce microbes, viruses, and nutrients such as nitrogen and phosphorous into nearshore waters which likely affect the native species. We collected surface water samples from four Chicago area beaches – Gillson Park, Montrose Beach, 57th Street Beach, and Calumet Beach – every two weeks from May 13 through August 5, 2014. …