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Kinetics Of Adp-Induced Human Platelet Shape Change: Apparent Positive Cooperativity, John Milton, W. Yung, C. Glushak, Mony M. Frojmovic Jan 1980

Kinetics Of Adp-Induced Human Platelet Shape Change: Apparent Positive Cooperativity, John Milton, W. Yung, C. Glushak, Mony M. Frojmovic

WM Keck Science Faculty Papers

The kinetics of ADP-induced human platelet shape change have been examined. Initial velocities of platelet shape change were estimated by two methods: 1) the slope of the initial decrease in light transmission through stirred, citrated platelet-rich plasma, and 2) direct examination of platelet morphologies by phase-contrast microscopy. In both cases, a value of the Hill coefficient, n, significantly greater than 1 is obtained (2.0 +/- 0.2 and 1.8 +/- 0.2, respectively). The observed elevated value of n is not due to a substantial fraction of the ADP being platelet bound, the presence of factors in the plasma, platelet heterogeneity, of …


Liverpool University Expedition To Jamaica, Donald A. Mcfarlane Jan 1980

Liverpool University Expedition To Jamaica, Donald A. Mcfarlane

WM Keck Science Faculty Papers

During summer 1977, five members of the Liverpool University Potholing Club spent six weeks working and exploring in the caves of Jamaica. The team consisted of Don McFarlane, John Dye, Malcolm Macduff, Mike Roger and Barry Williams, all of whom contributed to this report. The expedition base was at Troy, where the villagers are owed a debt of gratitude for their hospitality. This placed the expedition in the heart of the cave region, and a number of new caves and shafts were discovered and explored. The main discovery was the Still Waters Cave, located near Accompong, where 11,800 feet of …