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Beyond Bmi: The “Metabolically Healthy Obese” Phenotype & Its Association With Clinical/Subclinical Cardiovascular Disease And All-Cause Mortality -- A Systematic Review, Lara L. Roberson, Ehimen C. Aneni, Wasim Maziak, Arthur Agatston, Theodore Feldman, Maribeth Rouseff, Thinh Tran, Michael J. Blaha, Raul D. Santos, Andrei Sposito, Mouaz H. Al-Mallah, Ron Blankenstein, Matthew J. Budoff, Khurram Nasir
Beyond Bmi: The “Metabolically Healthy Obese” Phenotype & Its Association With Clinical/Subclinical Cardiovascular Disease And All-Cause Mortality -- A Systematic Review, Lara L. Roberson, Ehimen C. Aneni, Wasim Maziak, Arthur Agatston, Theodore Feldman, Maribeth Rouseff, Thinh Tran, Michael J. Blaha, Raul D. Santos, Andrei Sposito, Mouaz H. Al-Mallah, Ron Blankenstein, Matthew J. Budoff, Khurram Nasir
HWCOM Faculty Publications
Background
A subgroup has emerged within the obese that do not display the typical metabolic disorders associated with obesity and are hypothesized to have lower risk of complications. The purpose of this review was to analyze the literature which has examined the burden of cardiovascular disease (CVD) and all-cause mortality in the metabolically healthy obese (MHO) population.
Methods
Pubmed, Cochrane Library, and Web of Science were searched from their inception until December 2012. Studies were included which clearly defined the MHO group (using either insulin sensitivity and/or components of metabolic syndrome AND obesity) and its association with either all cause …