Digital Commons Network^™

Evolution Of Vacuolar Pyrophosphatases And Vacuolar H+-Atpases In Diatoms, Adrien Bussard, Pascal Jean Lopez

Journal of Marine Science and Technology

To cope with changing environments and maintain optimal metabolic conditions, the control of the intracellular proton gradients has to be tightly regulated. Among the important proton pumps, vacuolar H+ -ATPases (V-ATPases) and H+ - translocating pyrophosphatases (H+ -PPases) were found to be involved in a number of physiological processes, and shown to be regulated at the expression level and to exhibit specific sub-cellular localizations. Studies of the role of these transporters are relatively scarce in algae and nearly absent in diatoms. Phylogenetic analyses disclose that diatoms, with both K+ -dependent and K+ -independent membrane integral pyrophosphatases, including proteins with high …