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- Climate change (2)
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- Anti-Mullerian hormone testing (1)
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- Bovine Lambda Cluster Deletion (1)
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- Immunoglobulin Gene Knockout (1)
- Johne’s disease (1)
- Life table response experiment; open top chambers (1)
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- Western dairy center (1)
Articles 1 - 11 of 11
Full-Text Articles in Entire DC Network
Registration Of ‘Newell’ Smooth Bromegrass, K P. Vogel, R B. Mitchell, B L. Waldron, M R. Haferkamp, J D. Berdahl, D D. Baltensperger, Galen Erickson, T J. Klopfenstein
Registration Of ‘Newell’ Smooth Bromegrass, K P. Vogel, R B. Mitchell, B L. Waldron, M R. Haferkamp, J D. Berdahl, D D. Baltensperger, Galen Erickson, T J. Klopfenstein
Green Canyon Environmental Research Area, Logan Utah
No abstract provided.
Efficient Gene Targeting In Golden Syrian Hamsters By The Crispr/Cas9 System, Zhiqiang Fan, Wei Li, Sang R. Lee, Qinggang Meng, Tom D. Bunch, Kenneth L. White, Zhongde Wang, Il-Keun Kong
Efficient Gene Targeting In Golden Syrian Hamsters By The Crispr/Cas9 System, Zhiqiang Fan, Wei Li, Sang R. Lee, Qinggang Meng, Tom D. Bunch, Kenneth L. White, Zhongde Wang, Il-Keun Kong
Animal, Dairy, and Veterinary Science Faculty Publications
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research. Here, we report the first successful application of the CRISPR/Cas9 system to efficiently conduct gene targeting in hamsters. We designed five synthetic single-guide RNAs (sgRNAs)—three for targeting the coding sequences for different functional domains of the hamster STAT2 protein, one for KCNQ1, and one for PPP1R12C—and demonstrated that the CRISPR/Cas9 system is highly efficient in introducing site-specific mutations in hamster somatic cells. We …
Warming, Competition, And Bromus Tectorum Population Growth Across An Elevation Gradient, Aldo Compagnoni, Peter B. Adler
Warming, Competition, And Bromus Tectorum Population Growth Across An Elevation Gradient, Aldo Compagnoni, Peter B. Adler
Green Canyon Environmental Research Area, Logan Utah
Cheatgrass (Bromus tectorum) is one of the most problematic invasive plant species in North America and climate change threatens to exacerbate its impacts. We conducted a two‐year field experiment to test the effect of warming, competition, and seed source on cheatgrass performance across an elevation gradient in northern Utah. We hypothesized that warming would increase cheatgrass performance, but that warming effects would be limited by competing vegetation and by local adaptation of cheatgrass seed sources. The warming treatment relied on open top chambers, we removed vegetation to assess the effect of competition from neighboring vegetation, and we reciprocally …
Schooling Increases Risk Exposure For Fish Navigating Past Artificial Barriers, Bertrand H. Lemasson, James W. Haefner, Mark D. Bowen
Schooling Increases Risk Exposure For Fish Navigating Past Artificial Barriers, Bertrand H. Lemasson, James W. Haefner, Mark D. Bowen
Biology Faculty Publications
Artificial barriers have become ubiquitous features in freshwater ecosystems and they can significantly impact a region's biodiversity. Assessing the risk faced by fish forced to navigate their way around artificial barriers is largely based on assays of individual swimming behavior. However, social interactions can significantly influence fish movement patterns and alter their risk exposure. Using an experimental flume, we assessed the effects of social interactions on the amount of time required for juvenile palmetto bass (Morone chrysops × M. saxatilis) to navigate downstream past an artificial barrier. Fish were released either individually or in groups into the flume …
How To Use Anti-Mullerian Hormone Testing To Diagnose Granulosa Cell Tumors In Mares, Dirk K. Vanderwall, Kerry A. Rood
How To Use Anti-Mullerian Hormone Testing To Diagnose Granulosa Cell Tumors In Mares, Dirk K. Vanderwall, Kerry A. Rood
All Current Publications
This fact sheet describes how to use Anti-Mullerian hormone testing to diagnose granulosa cell tumors in mares.
2013 Annual Report, Various Authors
Halogeton (H. Glomeratus) Poisoning In Cattle: Case Report, Kerry A. Rood, Kip E. Panter, Dale R. Gardner, Bryan L. Stegelmeier, Jeffery O. Hall
Halogeton (H. Glomeratus) Poisoning In Cattle: Case Report, Kerry A. Rood, Kip E. Panter, Dale R. Gardner, Bryan L. Stegelmeier, Jeffery O. Hall
Animal, Dairy, and Veterinary Science Faculty Publications
Historically, the most significant losses from halogeton poisoning have been reported in sheep, with multiple catastrophic deaths documented. While recorded death losses in cattle from halogeton poisoning are less common than in sheep, recent cases, including 2 reported here, and anecdotal reports from other ranchers suggest that the impact of halogeton losses in cattle herds in the western United States is much more widespread than originally thought. Halogeton may accumulate up to 30% oxalates; a small amount of the plant (300 g) is enough to cause death in sheep. Oxalates precipitate calcium from the blood, resulting in hypocalcemia, formation of …
Triple Immunoglobulin Gene Knockout Transchromosomic (Tc) Cattle: Bovine Lambda Cluster Deletion And Its Effect On Fully Human Polyclonal Antibody Production, H. Matsushita, A. Sano, H. Wu, J. Jiao, P. Kasinathan, E. J. Sullivan, Zhongde Wang, K. Kuroiwa
Triple Immunoglobulin Gene Knockout Transchromosomic (Tc) Cattle: Bovine Lambda Cluster Deletion And Its Effect On Fully Human Polyclonal Antibody Production, H. Matsushita, A. Sano, H. Wu, J. Jiao, P. Kasinathan, E. J. Sullivan, Zhongde Wang, K. Kuroiwa
Animal, Dairy, and Veterinary Science Faculty Publications
Towards the goal of producing fully human polyclonal antibodies (hpAbs or hIgGs) in transchromosomic (Tc) cattle, we previously reported that Tc cattle carrying a human artificial chromosome (HAC) comprising the entire unrearranged human immunoglobulin (Ig) heavy-chain (hIGH), kappa-chain (hIGK), and lambda-chain (hIGL) germline loci produced physiological levels of hIgGs when both of the bovine immunoglobulin mu heavy-chains, bIGHM and bIGHML1, were homozygously inactivated (bIGHM-/-, bIGHML1-/-; double knockouts or DKO). However, because endogenous bovine immunoglobulin light chain loci are still intact, the light chains are produced both from the hIGK and hIGL genomic loci on the HAC and from the endogenous …
Warming, Soil Moisture, And Loss Of Snow Increase Bromus Tectorum’S Population Growth Rate, Aldo Compagnoni, Peter B. Adler
Warming, Soil Moisture, And Loss Of Snow Increase Bromus Tectorum’S Population Growth Rate, Aldo Compagnoni, Peter B. Adler
Green Canyon Environmental Research Area, Logan Utah
Climate change threatens to exacerbate the impacts of invasive species. In temperate ecosystems, direct effects of warming may be compounded by dramatic reductions in winter snow cover. Cheatgrass (Bromus tectorum) is arguably the most destructive biological invader in basins of the North American Intermountain West, and warming could increase its performance through direct effects on demographic rates or through indirect effects mediated by loss of snow. We conducted a two-year experimental manipulation of temperature and snow pack to test whether 1) warming increases cheatgrass population growth rate and 2) reduced snow cover contributes to cheatgrass’ positive response to …
Johne's Disease, Mycoplasma And Bvd In Utah - Bulk Tank Milk Testing And Comparison To Previous Regional Prevalence And Individual Herd Results Over Time, David J. Wilson, Kerry A. Rood, J. Bunnell, C. Whitehouse, G. M. Goodell, T. M. Byrem
Johne's Disease, Mycoplasma And Bvd In Utah - Bulk Tank Milk Testing And Comparison To Previous Regional Prevalence And Individual Herd Results Over Time, David J. Wilson, Kerry A. Rood, J. Bunnell, C. Whitehouse, G. M. Goodell, T. M. Byrem
Animal, Dairy, and Veterinary Science Faculty Publications
Dairy herd-level prevalence of Mycobacterium avium subsp. paratuberculosis (MAP), causative agent of Johne’s disease (JD), Mycoplasma spp., and Bovine Viral Diarrhea (BVD) virus were estimated in Utah and surrounding states and compared to previous surveillance results. Milk was collected at 3-4 day intervals on 5 dates (duplicate samples) from each bulk tank on participating farms, samples analyzed separately. One frozen sample was shipped to a laboratory for JD/MAP testing with ELISA and real-time PCR, the other paired sample was shipped to another laboratory for mycoplasma and BVD testing. Mycoplasma was cultured on modified Hayflick medium, standard methods; BVD testing was …
Activating The Expression Of Human K-Rasg12d Stimulates Oncogenic Transformation In Transgenic Goat Fetal Fibroblast Cells, J. Gong, Zhongde Wang, I. Polejaeva, R. Salgia, C. Kao, T. Chen, L. Chen
Activating The Expression Of Human K-Rasg12d Stimulates Oncogenic Transformation In Transgenic Goat Fetal Fibroblast Cells, J. Gong, Zhongde Wang, I. Polejaeva, R. Salgia, C. Kao, T. Chen, L. Chen
Animal, Dairy, and Veterinary Science Faculty Publications
Humane use of preclinical large animal cancer models plays a critical role in understanding cancer biology and developing therapeutic treatments. Among the large animal candidates, goats have great potentials as sustainable sources for large animal cancer model development. Goats are easier to handle and cheaper to raise. The genome of the goats has been sequenced recently. It has been known that goats develop skin, adrenal cortex, breast and other types of cancers. Technically, goats are subject to somatic cell nuclear transfer more efficiently and exhibit better viability through the cloning process. Towards the development of a goat cancer model, we …