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Somatic Injury Precedes Distal Atrophy Following Excitotoxic Hippocampal Insult, Lynda Sharrett-Field 2010 University of Kentucky

Somatic Injury Precedes Distal Atrophy Following Excitotoxic Hippocampal Insult, Lynda Sharrett-Field

University of Kentucky Master's Theses

Excitotoxicity can lead to increases in intracellular Na+ and Ca2+ concentrations via the glutamatergic NMDA receptors, which can lead to cell death. Detailing the time-dependent degradation of neuronal components in response to excitotoxic challenge may help elucidate the sequence in which these signaling pathways are initiated and further, associate these pathways with topographic cellular demise. Using organotypic hippocampal slice culture technique, tissue from neonatal rat pups was exposed to NMDA, APV, or co-exposed for 24, 72 or 120 hours. Fluorescent microscopy of propidium iodide (PI) was used to evaluate neuronal membrane damage, changes in the density of mature soma ...


Time-Dependence Of Distal-To-Proximal Hippocampal Neurodegeneration Produced By N-Methyl-D-Aspartate Receptor Activation, Jennifer Nicole Berry 2010 University of Kentucky

Time-Dependence Of Distal-To-Proximal Hippocampal Neurodegeneration Produced By N-Methyl-D-Aspartate Receptor Activation, Jennifer Nicole Berry

University of Kentucky Master's Theses

Excitotoxicity is the overexcitation of neurons due to the excessive activation of excitatory amino acid receptors and is thought to be involved in many neurodegenerative states. The manner in which the neuron breaks down during excitotoxicity is still unclear. The current study used the organotypic hippocampal slice culture model to examine the time-dependent loss of the synaptic vesicular protein synaptophysin and the loss of N-methyl-D-aspartate (NMDA) receptor NR1 subunit availability following an excitotoxic insult (20 μM NMDA) to provide a better understanding of the topographical nature of neuronal death following NMDA receptor activation. Significant NMDA-induced cytotoxicity in the CA1 ...


Health Literacy: A Bibliometric And Citation Analysis, Robert M. Shapiro II 2010 University of Kentucky

Health Literacy: A Bibliometric And Citation Analysis, Robert M. Shapiro Ii

University of Kentucky Master's Theses

The concept of health literacy finds its origins in the field of education. In its brief history the definition, structure, and direction of the field has changed dramatically and has emerged as a multidisciplinary endeavor full of discipline specific manifestations, most recently, public health literacy. Using bibliometric and citation analyses, this study investigated the field of health literacy from the first use of the term in 1974 to the present year, 2010. A range of databases from the various fields that have contributed to the field were searched using the keyword string, “health literacy.” Data was organized, cleaned and parsed ...


A Comparison Of The Reiss Profile With The Neo Pi-R Assessment Of Personality, Sara E. Boyd 2010 University of Kentucky

A Comparison Of The Reiss Profile With The Neo Pi-R Assessment Of Personality, Sara E. Boyd

University of Kentucky Master's Theses

The purpose of this thesis was to determine whether the NEO Personality Inventory-Revised (NEO PI-R) could account for significant variance within a measure of personality developed for the intellectually disabled (i.e., the Reiss Profile of Fundamental Motives), as well as to consider their comparative validity. The NEO PI-R and the Reiss Profile of Fundamental Motives were administered to 127 undergraduate students in conjunction with the Personality Research Form (PRF) and the Behavior Report Form (BRF). The NEO PI-R was able to account for a substantial amount of variance in the Reiss Profile scales, and the Reiss and the NEO ...


Nativist Notions: The Effects Of Anti-Immigration Parties On Mainstream Conservative Parties In Western European Democracies, Kathleen Gish 2010 University of Kentucky

Nativist Notions: The Effects Of Anti-Immigration Parties On Mainstream Conservative Parties In Western European Democracies, Kathleen Gish

University of Kentucky Master's Theses

This is an analysis of flank and shift effects in political sociology that focuses on anti-immigrant parties in eight European countries. In a positive radical flank effect the radical party makes the moderate and mildly-threatening parties look good. In turn, that moderate party then gains power or at least many of their ends. A negative radical flank effect occurs when the actual or perceived association of the moderate party with the radical party causes the moderate party to lose support. Radical shift effects are when the moderate or conservative party shifts its policy toward the radical direction. In this case ...


Law And Ideology In The U.S. Courts Of Appeals Judicial Review Of Federal Agency Decisions, Jerry D. Thomas 2010 University of Kentucky

Law And Ideology In The U.S. Courts Of Appeals Judicial Review Of Federal Agency Decisions, Jerry D. Thomas

University of Kentucky Doctoral Dissertations

The attitudinal model of judicial behavior dominates judicial politics scholarship, including studies of federal courts and agencies. Extant research finds limited support for legal constraints as determinants of judge behavior when agency decisions are under review. Attitudinal scholars suggest judges substitute their policy preferences in place of agency preferences. Contrarily, the legal model suggests judges defer to agencies because of procedures and doctrine rooted in the rule of law.

This study tests hypotheses predicting whether federal agency review decisions in the U.S. Courts of Appeals during 1982-2002 are a function of judges‘ attitudes, namely ideology, or a function of ...


Faculty Manual, 2010-2011, Clemson University 2010 Clemson University

Faculty Manual, 2010-2011, Clemson University

Faculty Manuals

No abstract provided.


Aboriginal Practitioners Speak Out: Contextualising Child Protection Interventions, Dawn Bessarab, Frances Crawford 2010 Centre for International Health

Aboriginal Practitioners Speak Out: Contextualising Child Protection Interventions, Dawn Bessarab, Frances Crawford

Aboriginal Policy Research Consortium International (APRCi)

One month before the June 2007 Federal Government Emergency Intervention in the Northern Territory some 55 West Australian Aboriginal child protection workers attended a 3-day summit in Fremantle. Their purpose as front-line practitioners from across the State was to identify how more nurturing and healing communities could be developed and supported in a climate of despair. This paper reports on how the summit was designed and on some of the ideas and concerns that emerged within this dialogical space of cooperative inquiry. The project was a partnership between Aboriginal and non-Aboriginal representatives of university, government, and community-service bodies. Aboriginal practitioners ...


Hypermedia Space And Global Communication Studies: Lessons From The Middle East, Marwan M. Kraidy, Sara Mourad 2010 University of Pennsylvania

Hypermedia Space And Global Communication Studies: Lessons From The Middle East, Marwan M. Kraidy, Sara Mourad

Departmental Papers (ASC)

No abstract provided.


Promoting System-Wide Cultural Competence For Serving Aboriginal Families And Children In A Midsized Canadian City, Ruby Ambtman, Suzanne Hudson, Reid Hartry, Dawne MacKay-Chiddenton 2010 Western University

Promoting System-Wide Cultural Competence For Serving Aboriginal Families And Children In A Midsized Canadian City, Ruby Ambtman, Suzanne Hudson, Reid Hartry, Dawne Mackay-Chiddenton

Aboriginal Policy Research Consortium International (APRCi)

This article describes the work of the Circle of Courage, a cross– cultural group committed to improving the cultural competence of organizations providing services to Aboriginal populations in a midsized city in Canada. Rather than concentrating on indi- viduals’ cultural competence, the Circle targets mainstream orga- nizations. Many of its activities, therefore, require organizations to examine themselves and make systemic changes. Providing support to Aboriginal staff of mainstream organizations is a significant element of the Circle’s initiatives. After an analysis of cultural proficiency—particularly at the organizational and systemic levels—the history of the Circle, its internal functioning, and ...


Competing Demands Of Prosociality & Equity In Monkeys, Sarah F. Brosnan, Daniel Houser, Kristin Leimgruber, Erte Xiao, Tianwen Chen, Frans B.M. de Waal 2010 Georgia State University

Competing Demands Of Prosociality & Equity In Monkeys, Sarah F. Brosnan, Daniel Houser, Kristin Leimgruber, Erte Xiao, Tianwen Chen, Frans B.M. De Waal

Psychology Faculty Publications

Prosocial decisions may lead to unequal payoffs among group members. Although an aversion to inequity has been found in empirical studies of both human and nonhuman primates, the contexts previously studied typically do not involve a trade-off between pro-sociality and inequity. Here we investigate the apparent co-existence of these two factors, specifically the competing demands of prosociality and equity. We directly compare the responses of brown capuchin monkeys (Cebus apella) among situations where pro-social preferences conflict with equality, using a paradigm comparable to other studies of cooperation and inequity in this species. By choosing to pull a tray towards themselves ...


Sisters In Spirit Research Framework: Reflecting On Methodology And Process, Jennifer King 2010 Western University

Sisters In Spirit Research Framework: Reflecting On Methodology And Process, Jennifer King

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Searching Together: A Model For Community-Driven Research In Remote First Nations, Judy Finlay, Anna Nagy, Connie Gray-McKay 2010 Western University

Searching Together: A Model For Community-Driven Research In Remote First Nations, Judy Finlay, Anna Nagy, Connie Gray-Mckay

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Finding The Keys To Unlock Successful Aboriginal Community Governance: Case Studies Of Three Aboriginal Councils In North Queensland, Australia, Michael Limerick 2010 Western University

Finding The Keys To Unlock Successful Aboriginal Community Governance: Case Studies Of Three Aboriginal Councils In North Queensland, Australia, Michael Limerick

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


In Praise Of Taxes: The Link Between Taxation And Good Governance In A First Nations Context, John Graham, Jodi Bruhn 2010 Western University

In Praise Of Taxes: The Link Between Taxation And Good Governance In A First Nations Context, John Graham, Jodi Bruhn

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Explaining Aboriginal Turnout In Federal Elections: Evidence From Alberta, Saskatchewan, And Manitoba, Allison Harell, Dimitrios Panagos, J. Scott Matthews 2010 Western University

Explaining Aboriginal Turnout In Federal Elections: Evidence From Alberta, Saskatchewan, And Manitoba, Allison Harell, Dimitrios Panagos, J. Scott Matthews

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Domestic Sex Trafficking Of Aboriginal Girls In Canada: Issues And Implications, Anupriya Sethi 2010 Western University

Domestic Sex Trafficking Of Aboriginal Girls In Canada: Issues And Implications, Anupriya Sethi

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


The Social Determinants Of Health: Defining A Research Agenda For Canada’S Urban Aboriginal Population, Chantelle Richmond, Katie Big-Canoe 2010 Western University

The Social Determinants Of Health: Defining A Research Agenda For Canada’S Urban Aboriginal Population, Chantelle Richmond, Katie Big-Canoe

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Disproportionate And Unjustifiable: Teen First Nations Mothers And Unstated Paternity Policy, Michelle Mann 2010 Western University

Disproportionate And Unjustifiable: Teen First Nations Mothers And Unstated Paternity Policy, Michelle Mann

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Scientific Certainty In A Time Of Uncertainty: Predicting Vulnerability Of Canada’S First Nations To The H1n1/09 Pandemic, Nicholas Spence 2010 Western University

Scientific Certainty In A Time Of Uncertainty: Predicting Vulnerability Of Canada’S First Nations To The H1n1/09 Pandemic, Nicholas Spence

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


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