Statistical Models Commons^™

Modeling Biphasic, Non-Sigmoidal Dose-Response Relationships: Comparison Of Brain- Cousens And Cedergreen Models For A Biochemical Dataset, Venkat D. Abbaraju, Tamaraty L. Robinson, Brian P. Weiser

Rowan-Virtua School of Osteopathic Medicine Faculty Scholarship

Biphasic, non-sigmoidal dose-response relationships are frequently observed in biochemistry and pharmacology, but they are not always analyzed with appropriate statistical methods. Here, we examine curve fitting methods for “hormetic” dose-response relationships where low and high doses of an effector produce opposite responses. We provide the full dataset used for modeling, and we provide the code for analyzing the dataset in SAS using two established mathematical models of hormesis, the Brain-Cousens model and the Cedergreen model. We show how to obtain and interpret curve parameters such as the ED50 that arise from modeling, and we discuss how curve parameters might change …

A Comparison Of Confidence Intervals In State Space Models, Jinyu Du

Statistical Science Theses and Dissertations

This thesis develops general procedures for constructing confidence intervals (CIs) of the error disturbance parameters (standard deviations) and transformations of the error disturbance parameters in time-invariant state space models (ssm). With only a set of observations, estimating individual error disturbance parameters accurately in the presence of other unknown parameters in ssm is a very challenging problem. We attempted to construct four different types of confidence intervals, Wald, likelihood ratio, score, and higher-order asymptotic intervals for both the simple local level model and the general time-invariant state space models (ssm). We show that for a simple local level model, both the …

On Image Response Regression With High-Dimensional Data, Noah Fuerth

Major Papers

A recent issue in statistical analysis is modelling data when the effect variable

changes at different locations. This can be difficult to accomplish when the dimensions

of the covariates are very high, and when the domain of the varying coefficient

functions of predictors are not necessarily regular. This research paper will investigate

a method to overcome these challenges by approximating the varying coefficient

functions using bivariate splines. We do this by splitting the domain of the varying

coefficient functions into a number of triangles, and build the bivariate spline functions

based on this triangulation. This major paper will outline detailed …

Addressing The Impact Of Time-Dependent Social Groupings On Animal Survival And Recapture Rates In Mark-Recapture Studies, Alexandru M. Draghici

Electronic Thesis and Dissertation Repository

Mark-recapture (MR) models typically assume that individuals under study have independent survival and recapture outcomes. One such model of interest is known as the Cormack-Jolly-Seber (CJS) model. In this dissertation, we conduct three major research projects focused on studying the impact of violating the independence assumption in MR models along with presenting extensions which relax the independence assumption. In the first project, we conduct a simulation study to address the impact of failing to account for pair-bonded animals having correlated recapture and survival fates on the CJS model. We examined the impact of correlation on the likelihood ratio test (LRT), …

Analytical Approach For Monitoring The Behavior Of Patients With Pancreatic Adenocarcinoma At Different Stages As A Function Of Time, Aditya Chakaborty Dr, Chris P. Tsokos Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.

Predicting Dengue Incidence In Central Argentina Using Google Trends Data, Sahil Chindal, Elizabet Estallo, Yanjun Qian, Michael Robert

Biology and Medicine Through Mathematics Conference

No abstract provided.

Public Acceptance Of Guidance And Regulations For Space Flight Participation, Cory Trunkhill, Robert Joslin, Joseph Keebler

Journal of Aviation Technology and Engineering

Space flight participants are not professional astronauts and not subject to the rules and guidance covering space flight crewmembers. Ordinal logistic regression of survey data was utilized to explore public acceptance of current medical screening recommendations and regulations for safety risk and implied liability for civil space flight participation. Independent variables constituted participant demographic representations while dependent variables represented current Federal Aviation Administration guidance and regulations. Odds ratios were derived based on the demographic categories to interpret likelihood of acceptance for the criteria. Significant likely acceptance of guidance and regulations was found for five of twelve demographic variables influencing public …

Evaluating Models Of Scanpath Prediction, Matthias Kümmerer, Matthias Bethge

MODVIS Workshop

No abstract provided.

Optimizing Tumor Xenograft Experiments Using Bayesian Linear And Nonlinear Mixed Modelling And Reinforcement Learning, Mary Lena Bleile

Statistical Science Theses and Dissertations

Tumor xenograft experiments are a popular tool of cancer biology research. In a typical such experiment, one implants a set of animals with an aliquot of the human tumor of interest, applies various treatments of interest, and observes the subsequent response. Efficient analysis of the data from these experiments is therefore of utmost importance. This dissertation proposes three methods for optimizing cancer treatment and data analysis in the tumor xenograft context. The first of these is applicable to tumor xenograft experiments in general, and the second two seek to optimize the combination of radiotherapy with immunotherapy in the tumor xenograft …

Movie Recommender System Using Matrix Factorization, Roland Fiagbe

Data Science and Data Mining

Recommendation systems are a popular and beneficial field that can help people make informed decisions automatically. This technique assists users in selecting relevant information from an overwhelming amount of available data. When it comes to movie recommendations, two common methods are collaborative filtering, which compares similarities between users, and content-based filtering, which takes a user’s specific preferences into account. However, our study focuses on the collaborative filtering approach, specifically matrix factorization. Various similarity metrics are used to identify user similarities for recommendation purposes. Our project aims to predict movie ratings for unwatched movies using the MovieLens rating dataset. We developed …

Comparing Hierarchical Data Structures And Hierarchical Data Analysis, Halley Jeanne Dante, Robert Rovetti

Honors Thesis

Real world data is inherently noisy and data analysis can be especially complex when noise is compounded in hierarchical and multilevel data structures. Since such data structures can be described using multiple approaches, the way data is collapsed and grouped within these structures can influence its resulting interpretation and analyses. To avoid discrepancies in data collapsing and grouping, multiple statistical approaches have been developed specifically to analyze multilevel data structures. Examples of multilevel statistical models are the two-factor ANOVA and the general linear model with repeated-measures (GLM-RR) which is typically used in the context of looking at change over time. …

Factors Affecting Apothecia Production And Primary Infection By Monilinia Vaccinii-Corymbosi On Vaccinium Angustifolium, Ian Leonard

Electronic Theses and Dissertations

Mummy berry, caused by Monilinia vaccinii-corymbosi (MVC), is a prolific disease of Vaccinium angustifolium (wild blueberry) leading to decreased yield in wild blueberry fields throughout the Downeast (DE) and Midcoast (MC) regions of Maine (ME). This study aimed to identify factors affecting primary inoculum production and infection by MVC on wild blueberry, and what bud stages of wild blueberry are most susceptible to infection. Through common garden (CGE), field and incubation experiments conducted in 2021 and 2022, factors affecting carpogenic germination of MVC pseudosclerotia and relationships between susceptible wild blueberry buds and environmental factors were analyzed. The CGE conducted in …

A Probabilistic Exploration Of Food Supplementation And Assistance, Logan Mattingly

Honors College Theses

Food insecurity is a stark threat that grips our country and affects households throughout our country. Dietary insufficiency manifests itself in ways that affect health and public safety. According to researchers, individuals who suffer from food insecurity have a higher risk of aggression, anxiety, suicide ideation and depression. These problems tend to occur unequally distributed among those households with lower income. In this work, an exploratory analysis within these data sets will be performed to examine the socio-economic, biographical, nutritional, and geographical principal components of food insecurity among survey participants and how the US Supplemental Nutrition Assistance Program (SNAP) effects …

Hispanic Human Capital And Financial Aid Application In The West Census Region, Benjamin Lundy-Paine

Capstone Projects and Master's Theses

As of 2021, very few Hispanic residents in the United States held a college degree in comparison to non-Hispanic residents. Research has shown that, particularly for Hispanic students, financial aid increases college persistence. Hispanic Free Application for Federal Student Aid (FAFSA) submission rates rank among the lowest, preventing many Hispanic students from receiving financial assistance. This issue is most prevalent West Census Region (WCR), where there is the highest concentration of Hispanic residents. To understand what barriers may be preventing Hispanic submission in the WCR this Capstone used logistic regression models to analyze student-level data from the National Center for …

Multidimensional Investigation Of Tennessee’S Urban Forest, Jillian L. Gorrell

Doctoral Dissertations

Preserving existing trees in urban areas and properly cultivating urban forest conservation and management opportunities is valuable to the ever-growing urban environment and necessary for creating optimal experiences and educational tools to meet the needs of increasing urban populations. This dissertation contains studies investigating several facets of the urban forest, including environmental effects of deforestation and urbanization, tree equity, and urban forest facility management and accessibility. Community education and outreach at arboreta about the importance of the tree canopy can help promote environmental stewardship. A digital questionnaire was electronically distributed to representatives of arboreta certified through the Tennessee Division of …

An Analysis Of Changes In Seasonal Dynamics And Generational Differences In The Maine Lobster Fishery, Emily Fitting

Electronic Theses and Dissertations

The American lobster (Homarus americanus) supports the most valuable single species fishery in the US. Lobster landings have been increasing steadily for the last three decades, but before that landings were more variable. The high value of the lobster fishery combined with the decline of other commercially important species in this region has created increasing dependence on the resource, and previous research questions the resilience of the fishery in the face of social and environmental changes.

Important lobster life history processes, including migration patterns, growth rates, and reproduction, are driven by ocean bottom temperature, which creates a strong seasonal cycle …

Baseball’S Evolution In The 21st Century, And How It Exemplifies Human Response To Change, Jonathan Sharpe

Honors Projects

The game of baseball has changed a lot in the past twenty years. It can be primarily attributed to the explosion in data analytics and how they are used to evaluate baseball players. This led to different player profiles being preferred and eventually led to the development of players changing. As a result, the strategies employed have also evolved and turned into a different game than seen only a couple of decades ago. This paper will explore the changes that the game has seen. On the other hand, Major League Baseball has also implemented its own changes to try and …

Effects Of Functional Network Model Definition On Biomarker Outcome Prediction, Xinyang Feng

Arts & Sciences Electronic Theses and Dissertations

Machine learning (ML) models are widely used to investigate the human connectome and to predict and understand behavior, emotion, and cognition. Prior research has organized pediatric connectome data using adult functional network models. However, this assumes that adult functional network models are appropriate and useful for prediction developmental outcomes from pediatric connectome data. We hypothesize that the application of adult brain network models could result in poor model fit, limiting the generalizability of results. Here, we test whether prediction of biological age is improved by concordant brain network models matching underlying functional connectome data. To quantify the difference in age …

Uconn Baseball Batting Order Optimization, Gavin Rublewski, Gavin Rublewski

Honors Scholar Theses

Challenging conventional wisdom is at the very core of baseball analytics. Using data and statistical analysis, the sets of rules by which coaches make decisions can be justified, or possibly refuted. One of those sets of rules relates to the construction of a batting order. Through data collection, data adjustment, the construction of a baseball simulator, and the use of a Monte Carlo Simulation, I have assessed thousands of possible batting orders to determine the roster-specific strategies that lead to optimal run production for the 2023 UConn baseball team. This paper details a repeatable process in which basic player statistics …

Small But Mighty: Examing The Utility Of Microstatistics In Modeling Ice Hockey, Matt Palmer

Senior Honors Theses

As research into hockey analytics continues, an increasing number of metrics are being introduced into the knowledge base of the field, creating a need to determine whether various stats are useful or simply add noise to the discussion. This paper examines microstatistics – manually tracked metrics which go beyond the NHL’s publicly released stats – both through the lens of meta-analytics (which attempt to objectively assess how useful a metric is) and modeling game probabilities. Results show that while there is certainly room for improvement in understanding and use of microstats in modeling, the metrics overall represent an area of …