Physical Sciences and Mathematics Commons^™

A Techno-Economic Analysis Of Carbon Dioxide Bio-Mitigation Using Microalgae, Samuel Morton, C. Fisk

Samuel A Morton

No abstract provided.

Application Of Layered Double Hydroxides To The Production Of Renewable Diesel, T. Morgan, D. Grubb, E. Santillian-Jimenez, Samuel Morton, M. Crocker

Samuel A Morton

No abstract provided.

Targeting Prostate Cancer Cells In Vivo Using A Rapidly Internalizing Novel Human Single-Chain Antibody Fragment., Arun K. Iyer

Arun Iyer

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human antibody fragment, a small-size platform, to provide high contrast in a mouse model of human prostate carcinoma. METHODS: A prostate tumor-targeting single-chain antibody fragment (scFv), UA20, along with a nonbinding control scFv, N3M2, were labeled with (99m)Tc and evaluated for binding and rapid internalization into human prostate tumor cells in vitro and tumor homing in vivo using xenograft models. For the in vitro studies, the labeled UA20 scFv was incubated …

Beethoven: Patriotism And Social Justice, Fathi Habashi

Fathi Habashi

Radio Emission From Substellar Companions Of Evolved Cool Stars., Richard Ignace, Mark L. Giroux, Donald G. Luttermoser

Richard Ignace

A number of substellar companions to evolved cool stars have now been reported. Cool giants are distinct from their progenitor main-sequence low-mass stars in a number of ways. First, the mass loss rates of cool giant stars are orders of magnitude greater than for the late-type main-sequence stars. Secondly, on the cool side of the Linsky–Haisch ‘dividing line’, K and M giant stars are not X-ray sources, although they do show evidence for chromospheres. As a result, cool star winds are largely neutral for those spectral types, suggesting that planetary or brown dwarf magnetospheres will not be effective in standing …

Portfolios In Stochastic Local Search: Efficiently Computing Most Probable Explanations In Bayesian Networks, Ole J. Mengshoel, D Roth, D Wilkins

Ole J Mengshoel

Portfolio methods support the combination of different algorithms and heuristics, including stochastic local search (SLS) heuristics, and have been identified as a promising approach to solve computationally hard problems. While successful in experiments, theoretical foundations and analytical results for portfolio-based SLS heuristics are less developed. This article aims to improve the understanding of the role of portfolios of heuristics in SLS. We emphasize the problem of computing most probable explanations (MPEs) in Bayesian networks (BNs). Algorithmically, we discuss a portfolio-based SLS algorithm for MPE computation, Stochastic Greedy Search (SGS). SGS supports the integration of different initialization operators (or initialization heuristics) …

Functional Generalized Linear Models With Images As Predictors, Philip T. Reiss, R. Todd Ogden

Philip T. Reiss

Functional principal component regression (FPCR) is a promising new method for regressing scalar outcomes on functional predictors. In this paper we present a theoretical justification for the use of principal components in functional regression. FPCR is then extended in two directions: from linear to the generalized linear modeling, and from univariate signal predictors to high-resolution image predictors. We show how to implement the method efficiently by adapting generalized additive model technology to the functional regression context. A technique is proposed for estimating simultaneous confidence bands for the coefficient function; in the neuroimaging setting, this yields a novel means to identify …

Radio Emission From Substellar Companions Of Evolved Cool Stars., Richard Ignace, Mark L. Giroux, Donald G. Luttermoser

Donald G. Luttermoser

A number of substellar companions to evolved cool stars have now been reported. Cool giants are distinct from their progenitor main-sequence low-mass stars in a number of ways. First, the mass loss rates of cool giant stars are orders of magnitude greater than for the late-type main-sequence stars. Secondly, on the cool side of the Linsky–Haisch ‘dividing line’, K and M giant stars are not X-ray sources, although they do show evidence for chromospheres. As a result, cool star winds are largely neutral for those spectral types, suggesting that planetary or brown dwarf magnetospheres will not be effective in standing …

Education In The Environment: A Strategy For Continued Interagency Outdoor Education Programming: Quarterly Progress Report: Period Ending February 28, 2010, Margaret N. Rees

Reports (PLI Education)

Highlights of the university’s focused efforts during the past three months include the following:

• A total of 56 people participated in a Families in Nature event at the Spring Mountains National Recreation Area
• More than 225 people are expected to attend the Our Places Tell Stories Conference, February 24 -27, 2010
• Forever Earth was scheduled for 19 days this quarter and benefited 622 individuals.
• Nine Discover Mojave Outdoor World events were conducted for 199 participants.

Interview With Jacquin Dole, Riverside Farms, 2010 (Audio), Jacquin Dole

All Sustainability History Project Oral Histories

Interview of Jacquin Dole by Paul Hopper at Riverside Farm McMinnville, Oregon on February 28th, 2010.

The interview index is available for download.

Interview With Bernard Smith, Full Of Life Farms, 2010 (Audio), Bernard Smith

All Sustainability History Project Oral Histories

Interview of Bernard Smith by Kyle Dykstra on February 28th, 2010.

The interview index is available for download.

A³: An Extensible Platform For Application-Aware Anonymity, Micah Sherr, Andrew Mao, William R. Marczak, Wenchao Zhou, Boon Thau Loo, Matthew A. Blaze

Departmental Papers (CIS)

This paper presents the design and implementation of Application-Aware Anonymity (A³), an extensible platform for deploying anonymity-based services on the Internet. A³ allows applications to tailor their anonymity properties and performance characteristics according to specific communication requirements. To support flexible path construction, A³ exposes a declarative language (A³LOG) that enables applications to compactly specify path selection and instantiation policies executed by a declarative networking engine. We demonstrate that our declarative language is sufficiently expressive to encode novel multi-metric performance constraints as well as existing relay selection algorithms employed by Tor and other anonymity systems, using only a few lines of …

Selective Regulation Of Aromatase Expression For Drug Discovery, Robert W. Brueggemeier, Bin Su, Michael V. Darby, Yasuro Sugimoto

Chemistry Faculty Publications

Aromatase is a particularly attractive drug target in the treatment of hormone-responsive breast cancer, and aromatase activity in breast cancer patients is greater in or near the tumor tissue compared with the normal breast tissue. Complex regulation of aromatase expression in human tissues involves alternative promoter sites that provide tissue-specific control. Previous studies in our laboratories suggested a strong association between aromatase (CYP19) gene expression and the expression of cyclooxygenase (COX) genes. Additionally, COX selective inhibitors can suppress CYP19 gene expression and decrease aromatase activity. Our current hypothesis is that pharmacological regulation of aromatase can act locally to decrease the …

40th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University

Student Research Conference Select Presentations

No abstract provided.

Interview With Katy Kolker, Portland Fruit Tree Project, 2010 (Audio), Katy Kolker

All Sustainability History Project Oral Histories

Interview of Katy Kolker by Dan Stillinger in Portland, Oregon on February 27th, 2010.

The interview index is available for download.

Geodetic Imaging Of Plate Motions, Slip Rates, And Partitioning Of Deformation In Japan, John P. Loveless, Brendan J. Meade

Geosciences: Faculty Publications

Interseismic deformation in Japan results from the combined effects of tectonic processes including rotation of crustal blocks and the earthquake cycle process of elastic strain accumulation about upper plate faults and subduction zone interfaces. We use spherical linear block theory constrained by geodetic observations from densely spaced Global Positioning System (GPS) stations to estimate plate motions, fault slip rates, and spatially variable interplate coupling on the Japan-Kuril, Sagami, and Nankai subduction zones. The reference model developed in this paper consists of 20 blocks, produces a mean residual velocity magnitude of 1.84 mm/yr at 950 stations, and accounts for 96% of …

Patent Examination Policy And The Social Costs Of Examiner Allowance And Rejection Errors, Ron D. Katznelson

Ron D. Katznelson

No abstract provided.

Ensuring Success With Program Reflection, Daphne Sewing

Our Places to Tell Stories

• Present a framework for program reflection
• Share ideas and tools
• Provide an opportunity to adapt for your program

Vortex Scattering And Intercommuting Cosmic Strings On A Noncommutative Spacetime, Anosh Joseph, Mark Trodden

Department of Physics Papers

We study the scattering of noncommutative vortices, based on the noncommutative field theory developed in [A. P. Balachandran, T. R. Govindarajan, G. Mangano, A. Pinzul, B. A. Qureshi, and S. Vaidya, Phys. Rev. D 75, 045009 (2007).], as a way to understand the interaction of cosmic strings. In the center-of-mass frame, the effects of noncommutativity vanish, and therefore the reconnection of cosmic strings occurs in an identical manner to the commutative case. However, when scattering occurs in a frame other than the center-of-mass frame, strings still reconnect but the well-known 90º scattering no longer need correspond to the head-on collision …

Biologically Inspired Computing: The Darpa Synapse Program & The Hierarchical Temporal Memory, Dan Hammerstrom

Systems Science Friday Noon Seminar Series

This presentation provides an update on biologically inspired computation. In particular, it focuses on two important developments in this area, the DARPA SyNAPSE program (Systems of Neuromorphic Adaptive Plastic Scalable Electronics) and the HTM (Hierarchical Temporal Memory) being developed by Numenta.

The SyNAPSE Program’s ultimate goal is to build a low-power, compact electronic chip combining novel analog circuit design and a neuroscience-inspired architecture that can address a wide range of cognitive abilities: perception, planning, decision making and motor control. According to DARPA program manager Todd Hylton, “Our research progress in this area is unprecedented, No suitable electronic synaptic device that …