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Physiologic Effects Of Nasopharyngeal Administration Of Supplemental Oxygen At Various Flow Rates In Healthy Neonatal Foals, David M. Wong, Cody J. Alcott, Chong Wang, Bonnie L. Hay-Kraus, Benjamin R. Buchanan, Charles W. Brockus 2010 Iowa State University

Physiologic Effects Of Nasopharyngeal Administration Of Supplemental Oxygen At Various Flow Rates In Healthy Neonatal Foals, David M. Wong, Cody J. Alcott, Chong Wang, Bonnie L. Hay-Kraus, Benjamin R. Buchanan, Charles W. Brockus

Veterinary Diagnostic and Production Animal Medicine Publications

Objective—To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (Fio2) and other arterial blood gas variables in healthy neonatal foals.

Animals—9 healthy neonatal (3- to 4-day-old) foals.

Procedures—In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the level of the medial canthus of each eye; oxygen was administered at 4 flow rates through either 1 or both cannulae (8 treatments/foal). Intratracheal Fio2, intratracheal end-tidal partial pressure of carbon dioxide, and arterial ...


Was Climate Change Involved?, Eugene S. Takle 2010 Iowa State University

Was Climate Change Involved?, Eugene S. Takle

Geological and Atmospheric Sciences Publications

No abstract provided.


Soil As A History Book, Bradley Allen Miller 2010 Iowa State University

Soil As A History Book, Bradley Allen Miller

Agronomy Publications

Soil is one of the most influential components of our enviroronment. It is a complex mixture of physical, chemical, and biological processes providing innumerable ecosystem services. The properties of our soil today support our way of life. It filters our water, contains our wastes, and is the substrate for the production of our food. Combined with a good climate, the convergence of the right soil properties here in Iowa has given its citizens the opportunity to be net exporters of food and feed. That opportunity gives Iowans the ability to feed themselves and prosper economically through the sale of excess ...


Sustainability Initiatives In East Bayside Neighborhood Portland, Maine, Garvan Donegan, Henry Heyburn, Caitlyn Horose, Matt Klebes, Jennifer Riley, Damon Yakovleff, New England Environmental Finance Center 2010 University of Southern Maine

Sustainability Initiatives In East Bayside Neighborhood Portland, Maine, Garvan Donegan, Henry Heyburn, Caitlyn Horose, Matt Klebes, Jennifer Riley, Damon Yakovleff, New England Environmental Finance Center

Planning

This is a bundle containing research on sustainability initiatives that could be implemented in the East Bayside neighborhood of Portland, ME. These six essays were prepared by the Spring, 2010 Sustainable Communities Class known as CPD 602 at the University of Southern Maine. The class is part of the core curriculum of the Community Planning and Development program of the Muskie School of Public Service at the university. The instructor for the class was Samuel Merrill, Ph. D. who is also director of the New England Environmental Finance Center at the University. These papers were prepared in conjunction with Alan ...


Valency Dependence Of Polymorphism And Polyamorphism In Dna-Functionalized Nanoparticles, Wei Dai, Chia Wei Hsu, Francesco Sciortino, Francis W. Starr 2010 Wesleyan University

Valency Dependence Of Polymorphism And Polyamorphism In Dna-Functionalized Nanoparticles, Wei Dai, Chia Wei Hsu, Francesco Sciortino, Francis W. Starr

Division III Faculty Publications

Nanoparticles (NP) functionalized with single-stranded DNA (ssDNA) offer a route to custom-designed, self- assembled nanomaterials with potentially unusual properties. The bonding selectivity of DNA guarantees one-to-one binding to form double-stranded DNA (dsDNA), and an appropriate base sequence results in head-to-tail binding linking NP into networks. We explore the phase behavior and structure of a model for NP functionalized with between 3 and 6 short ssDNA through simulations of a coarse-grained molecular model, allowing us to examine both the role of the number of attached strands (valency) and their relative orientations. The NP assemble into networks where the number of NP ...


Calculations Of The Binding Affinities Of Protein-Protein Complexes With The Fast Multipole Method, Bongkeun Kim, Jiming Song, Xueyu Song 2010 Iowa State University

Calculations Of The Binding Affinities Of Protein-Protein Complexes With The Fast Multipole Method, Bongkeun Kim, Jiming Song, Xueyu Song

Electrical and Computer Engineering Publications

In this paper, we used a coarse-grained model at the residue level to calculate the binding free energies of three protein-protein complexes. General formulations to calculate the electrostatic binding free energy and the van der Waals free energy are presented by solving linearized Poisson-Boltzmann equations using the boundary element method in combination with the fast multipole method. The residue level model with the fast multipole method allows us to efficiently investigate how the mutations on the active site of the protein-protein interface affect the changes in binding affinities of protein complexes. Good correlations between the calculated results and the experimental ...


Metabolic Engineering For Production Of Biorenewable Fuels And Chemicals: Contributions Of Synthetic Biology, Laura R. Jarboe, Xueli Zhang, Xuan Wang, Jonathan C. Moore, K. T. Shanmugam, Lonnie O. Ingram 2010 Iowa State University

Metabolic Engineering For Production Of Biorenewable Fuels And Chemicals: Contributions Of Synthetic Biology, Laura R. Jarboe, Xueli Zhang, Xuan Wang, Jonathan C. Moore, K. T. Shanmugam, Lonnie O. Ingram

Chemical and Biological Engineering Publications

Production of fuels and chemicals through microbial fermentation of plant material is a desirable alternative to petrochemicalbased production. Fermentative production of biorenewable fuels and chemicals requires the engineering of biocatalysts that can quickly and efficiently convert sugars to target products at a cost that is competitive with existing petrochemical-based processes. It is also important that biocatalysts be robust to extreme fermentation conditions, biomass-derived inhibitors, and their target products. Traditional metabolic engineering has made great advances in this area, but synthetic biology has contributed and will continue to contribute to this field, particularly with next-generation biofuels. This work reviews the use ...


Theoretical Study Of The Pyrolysis Of Methyltrichlorosilane In The Gas Phase. 3. Reaction Rate Constant Calculations, Yingbin Ge, Mark S. Gordon, Francine Battaglia, Rodney O. Fox 2010 Central Washington University

Theoretical Study Of The Pyrolysis Of Methyltrichlorosilane In The Gas Phase. 3. Reaction Rate Constant Calculations, Yingbin Ge, Mark S. Gordon, Francine Battaglia, Rodney O. Fox

Chemical and Biological Engineering Publications

The rate constants for the gas-phase reactions in the silicon carbide chemical vapor deposition of methyltrichlorosilane (Ge, Y. B.; Gordon, M. S.; Battaglia, F.; Fox, R. O. J. Phys. Chem. A 2007, 111, 1462.) were calculated. Transition state theory was applied to the reactions with a well-defined transition state; canonical variational transition state theory was applied to the barrierless reactions by finding the generalized transition state with the maximum Gibbs free energy along the reaction path. Geometry optimizations were carried out with second-order perturbation theory (MP2) and the cc-pVDZ basis set. The partition functions were calculated within the harmonic oscillator ...


An Extended Data Mining Method For Identifying Differentially Expressed Assay-Specific Signatures In Functional Genomic Studies, Derrick K. Rollins Sr., Ai-ling Teh 2010 Iowa State University

An Extended Data Mining Method For Identifying Differentially Expressed Assay-Specific Signatures In Functional Genomic Studies, Derrick K. Rollins Sr., Ai-Ling Teh

Chemical and Biological Engineering Publications

Background: Microarray data sets provide relative expression levels for thousands of genes for a small number, in comparison, of different experimental conditions called assays. Data mining techniques are used to extract specific information of genes as they relate to the assays. The multivariate statistical technique of principal component analysis (PCA) has proven useful in providing effective data mining methods. This article extends the PCA approach of Rollins et al. to the development of ranking genes of microarray data sets that express most differently between two biologically different grouping of assays. This method is evaluated on real and simulated data and ...


Automatic Generation Of Music For Inducing Emotive Response, Tony R. Martinez, Kristine Monteith, Dan A. Ventura 2010 Brigham Young University

Automatic Generation Of Music For Inducing Emotive Response, Tony R. Martinez, Kristine Monteith, Dan A. Ventura

Faculty Publications

We present a system that generates original music designed to match a target emotion. It creates n-gram models, Hidden Markov Models, and other statistical distributions based on musical selections from a corpus representing a given emotion and uses these models to probabilistically generate new musical selections with similar emotional content. This system produces unique and often remarkably musical selections that tend to match a target emotion, performing this task at a level that approaches human competency for the same task.


Evaluating Models Of Latent Document Semantics In The Presence Of Ocr Errors, Daniel D. Walker, William B. Lund, Eric K. Ringger 2010 Brigham Young University - Provo

Evaluating Models Of Latent Document Semantics In The Presence Of Ocr Errors, Daniel D. Walker, William B. Lund, Eric K. Ringger

Faculty Publications

Models of latent document semantics such as the mixture of multinomials model and Latent Dirichlet Allocation have received substantial attention for their ability to discover topical semantics in large collections of text. In an effort to apply such models to noisy optical character recognition (OCR) text output, we endeavor to understand the effect that character-level noise can have on unsupervised topic modeling. We show the effects both with document-level topic analysis (document clustering) and with word-level topic analysis (LDA) on both synthetic and real-world OCR data. As expected, experimental results show that performance declines as word error rates increase. Common ...


Rapid Microwave-Assisted Acid Extraction Of Chromate Copper Arsenate (Cca)-Treated Southern Pine, Bin Yu 2010 Louisiana State University and Agricultural and Mechanical College

Rapid Microwave-Assisted Acid Extraction Of Chromate Copper Arsenate (Cca)-Treated Southern Pine, Bin Yu

LSU Master's Theses

Recovery of heavy metals from chromated copper arsenate (CCA) treated southern pine wood samples with three different dimension was investigated by recovery with acetic acid, oxalic acid and phosphoric acid in microwave reactor. Diluted phosphoric acid mixed with acetic acid was found to be very effective to remove copper, chromium, and arsenic from spent CCA-treated southern pine sawdust at a high temperature and in a short time. No single acid can totally recover all these three metals in one step in this method. Oxalic acid was effective in removing chromium and arsenic, and acetic acid was effective in removing copper ...


Integration Of Paleotempestology With Coastal Risk And Vulnerability Assessment: Case Studies From The Dominican Republic And Nicaragua, Devyani Kar 2010 Louisiana State University and Agricultural and Mechanical College

Integration Of Paleotempestology With Coastal Risk And Vulnerability Assessment: Case Studies From The Dominican Republic And Nicaragua, Devyani Kar

LSU Doctoral Dissertations

Hurricanes account for a significant portion of damages, injuries, and fatalities in the Caribbean. The Dominican Republic has had 3 major hurricane strikes in this century resulting in loss of lives for thousands of people and billions of US $ in economic loss. Major hurricanes had been relatively infrequent in north-eastern Nicaragua’s modern history until Hurricane Felix, a Category 5 storm, made landfall in the north-east in 2007. It caused 130 confirmed deaths and brought devastation to many villages. These events highlight a need for re-evaluation of hurricane risk based on a more comprehensive and long-term hurricane history. Using paleotempestological ...


Particle Analysis In Infrared Laser Desorption And Ablation, Xing Fan 2010 Louisiana State University and Agricultural and Mechanical College

Particle Analysis In Infrared Laser Desorption And Ablation, Xing Fan

LSU Doctoral Dissertations

The fundamental physical processes of mid infrared laser ablation in the context of laser desorption mass spectrometry were investigated. Understanding the mechanisms of infrared laser desorption and ablation can lead to improvements in these techniques and expand their applications. Particles were generated from glycerol irradiated at atmospheric pressure using a tunable infrared laser at wavelengths between 2.6 and 3.8 µm. The wavelength dependence of size distributions of ablated particles was measured. The particle concentration roughly tracked the infrared absorption spectrum of glycerol and the mean particle size tracked the inverse of the IR absorption. A novel approach, post ...


Augmented Breast Tumor Classification By Perfusion Analysis, Bruce Yu-Sun Lin 2010 Louisiana State University and Agricultural and Mechanical College

Augmented Breast Tumor Classification By Perfusion Analysis, Bruce Yu-Sun Lin

LSU Doctoral Dissertations

Magnetic resonance and computed tomography imaging aid in the diagnosis and analysis of pathologic conditions. Blood flow, or perfusion, through a region of tissue can be computed from a time series of contrast-enhanced images. Perfusion is an important set of physiological parameters that reflect angiogenesis. In cancer, heightened angiogenesis is a key process in the growth and spread of tumorous masses. An automatic classification technique using recovered perfusion may prove to be a highly accurate diagnostic tool. Such a classification system would supplement existing histopathological tests, and help physicians to choose the most optimal treatment protocol. Perfusion is obtained through ...


A Study Of The Elongation Of Fibrils Of The Alzheimer's Amyloid Beta Protein With A Coarse-Grained Force Field, Ana Rojas 2010 Louisiana State University and Agricultural and Mechanical College

A Study Of The Elongation Of Fibrils Of The Alzheimer's Amyloid Beta Protein With A Coarse-Grained Force Field, Ana Rojas

LSU Doctoral Dissertations

Alzheimer’s disease (AD) is a brain disorder named after the German psychiatrist Alois Alzheimer, who first described the disease in 1906. AD is a form of dementia, characterized by impairment of memory and other intellectual abilities, caused by the loss of neurons and synapses (the structures that permit communication between neurons) in certain regions of the brain. Although the mechanism by which neurons are affected is not yet well understood, research points to a small protein, the beta-amyloid peptide (Abeta), as the first suspect. Ab chains are present in the brains of healthy individuals, but in AD patients, they ...


Quantifying The Impact Of Data Quality On Searches For Gravitational Waves From Binary Coalescing Systems With Ligo, Jacob Peter Slutsky 2010 Louisiana State University and Agricultural and Mechanical College

Quantifying The Impact Of Data Quality On Searches For Gravitational Waves From Binary Coalescing Systems With Ligo, Jacob Peter Slutsky

LSU Doctoral Dissertations

Gravitational waves are ripples in space-time itself, predicted by Einstein's General theory of relativity, which propagate at the speed of light and are not scattered or extinguished by passing through matter almost at all. In particular, the gravitational waves from the coalescences of binary systems of compact objects, such as neutron stars and black holes, are exciting prospects for observation. The Laser Interferometer Gravitational-wave Observatory experiment intends to make the _x000C_first direct measurement of gravitational waves, and use the results to uncover new astrophysics. These observations will not be limited by extinction from dust and gas, and will probe ...


Resource Selection By Elk In An Agro-Forested Landscape Of Northwestern Nebraska, David M. Baasch, Justin W. Fischer, Scott E. Hygnstrom, Kurt C. Vercauteren, Andrew J. Tyre, Joshua J. Millspaugh, James W. Merchant, Jerry D. Volesky 2010 University of Nebraska - Lincoln

Resource Selection By Elk In An Agro-Forested Landscape Of Northwestern Nebraska, David M. Baasch, Justin W. Fischer, Scott E. Hygnstrom, Kurt C. Vercauteren, Andrew J. Tyre, Joshua J. Millspaugh, James W. Merchant, Jerry D. Volesky

Papers in Natural Resources

In recent years, elk have begun recolonizing areas east of the Rocky Mountains that are largely agroforested ecosystems composed of privately owned land where management of elk is an increasing concern due to crop and forage depredation and interspecific disease transmission. We used a Geographic Information System, elk use locations (n = 5013), random locations (n = 25,065), discrete-choice models, and information-theoretic methods to test hypotheses about elk resource selection in an agro-forested landscape located in the Pine Ridge region of northwestern Nebraska, USA. Our objectives were to determine landscape characteristics selected by female elk and identify publicly owned land within ...


Multiscale Modeling Of Cellular Systems In Biology, J. C. Dallon 2010 Brigham Young University

Multiscale Modeling Of Cellular Systems In Biology, J. C. Dallon

Faculty Publications

Here we review eight different multiscale modeling efforts dealing with cellular systems in biology. The first two models focus on collagen based tissue, one dealing with the biomechanical properties of the tissue and the other focusing on how the dermis is remodeled in scar tissue formation. The next two models deal with first avascular tumor growth and then the role of the vasculature in tumor growth. We then consider two models which use the Immersed Boundary method to model tissue properties and cell-cell adhesion. Finally we conclude with two models with treatments of the Cellular Potts Model. The first models ...


Microfluidic Devices Interfaced To Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry For Proteomics, Jeonghoon Lee 2010 Louisiana State University and Agricultural and Mechanical College

Microfluidic Devices Interfaced To Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry For Proteomics, Jeonghoon Lee

LSU Doctoral Dissertations

Microfluidic interfaces were developed for off-line matrix-assisted laser desorption/ionization mass spectrometry (MALDI). Microfluidic interfaces allow samples to be manipulated on-chip and deposited onto a MALDI target plate for analysis. For this research, microfluidic culturing devices and automated digestion and deposition microfluidic chip platforms were developed for the identification of proteins. The microfluidic chip components were fabricated on a poly(methyl methacrylate), PMMA, wafer using the hot embossing method and a molding tool with structures prepared via micromilling. One of the most important components of the chip system was a trypsin microreactor. An open channel microreactor was constructed in a ...


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