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Nona-Arginine Facilitates Delivery Of Quantum Dots Into Cells Via Multiple Pathways, Yi Xu, Betty Revon Liu, Han Jung Lee, Katie Shannon, Jeffrey G. Winiarz, Tien-Chun Wang, Huey-Jenn Chiang, Yue-Wern Huang 2010 Missouri University of Science and Technology

Nona-Arginine Facilitates Delivery Of Quantum Dots Into Cells Via Multiple Pathways, Yi Xu, Betty Revon Liu, Han Jung Lee, Katie Shannon, Jeffrey G. Winiarz, Tien-Chun Wang, Huey-Jenn Chiang, Yue-Wern Huang

Biological Sciences Faculty Research & Creative Works

Semiconductor quantum dots (QDs) have recently been used to deliver and monitor biomolecules, such as drugs and proteins. However, QDs alone have a low efficiency of transport across the plasma membrane. In order to increase the efficiency, we used synthetic nona-arginine (SR9), a cell-penetrating peptide, to facilitate uptake. We found that SR9 increased the cellular uptake of QDs in a noncovalent binding manner between QDs and SR9. Further, we investigated mechanisms of QD/SR9 cellular internalization. Low temperature and metabolic inhibitors markedly inhibited the uptake of QD/SR9, indicating that internalization is an energy-dependent process. Results from both the pathway ...


A Detailed Model Atmosphere Analysis Of Cool White Dwarfs In The Sloan Digital Sky Survey, Mukremin Kilic, Ted von Hippel, et al. 2010 Smithsonian Astrophysical Observatory

A Detailed Model Atmosphere Analysis Of Cool White Dwarfs In The Sloan Digital Sky Survey, Mukremin Kilic, Ted Von Hippel, Et Al.

Publications

We present optical spectroscopy and near-infrared photometry of 126 cool white dwarfs (WDs) in the Sloan Digital Sky Survey (SDSS). Our sample includes high proper motion targets selected using the SDSS and USNO-B astrometry and a dozen previously known ultracool WD candidates. Our optical spectroscopic observations demonstrate that a clean selection of large samples of cool WDs in the SDSS (and the SkyMapper, Pan-STARRS, and the Large Synoptic Survey Telescope data sets) is possible using a reduced proper motion diagram and a tangential velocity cut-off (depending on the proper motion accuracy) of 30 km s–1. Our near-infrared observations reveal ...


Statistical Methods For Automatic Crack Detection Based On Vibrothermography Sequence-Of-Images Data, Ming Li, Stephen D. Holland, William Q. Meeker 2010 Iowa State University

Statistical Methods For Automatic Crack Detection Based On Vibrothermography Sequence-Of-Images Data, Ming Li, Stephen D. Holland, William Q. Meeker

Aerospace Engineering Publications

Vibrothermography is a relatively new nondestructive evaluation technique for finding cracks through frictional heat generated from crack surface vibrations under external excitations. The vibrothermography inspection method provides a sequence of infrared images as output. We use a matched filter technique to increase the signal-to-noise ratio of the sequence-of-images data. An automatic crack detection criterion based on the features extracted from the matched filter output greatly increases the sensitivity of the vibrothermography inspection method. In this paper, we develop a three dimensional matched filter for the sequence-of-images data, present the statistical analysis for the matched filter output, and evaluate the probability ...


The Effectiveness Of Vertebrate Passage And Prevention Structures: A Study Of Boeckman Road In Wilsonville, Catherine E. de Rivera, Leslie L. Bliss-Ketchum 2010 Portland State University

The Effectiveness Of Vertebrate Passage And Prevention Structures: A Study Of Boeckman Road In Wilsonville, Catherine E. De Rivera, Leslie L. Bliss-Ketchum

Environmental Science and Management Faculty Publications and Presentations

One of the most obvious impacts roads have on the natural world is direct mortality to individual animals that attempt to cross roads. A less obvious but likely more important impact of roads on many species is habitat fragmentation. The ability for individuals to travel between subpopulations is the key to genetic diversity as well as ultimately the survival of the species. Considering these impacts and management goals to increase habitat connectivity, increased attention has been given to creating road design that reduces wildlife collisions. Most studies, however, have been in other countries or regions and most focus on connectivity ...


Context-Aware Query Recommendations, Alexandros NTOULAS, Heasoo HWANG, Lise GETOOR, Stelios PAPARIZOS, Hady Wirawan LAUW 2010 Singapore Management University

Context-Aware Query Recommendations, Alexandros Ntoulas, Heasoo Hwang, Lise Getoor, Stelios Paparizos, Hady Wirawan Lauw

Research Collection School Of Information Systems

Described is a search-related technology in which context information regarding a user's prior search actions is used in making query recommendations for a current user action, such as a query or click. To determine whether each set or subset of context information is relevant to the user action, data obtained from a query log is evaluated. More particularly, a query transition (query-query) graph and a query click (query-URL) graph are extracted from the query log; vectors are computed for the current action and each context/sub-context and evaluated against vectors in the graphs to determine current action-to-context similarity. Also ...


A New Framework For Rfid Privacy, Robert H. DENG, Yingjiu LI, Moti YUNG, Yunlei ZHAO 2010 Singapore Management University

A New Framework For Rfid Privacy, Robert H. Deng, Yingjiu Li, Moti Yung, Yunlei Zhao

Research Collection School Of Information Systems

Formal RFID security and privacy frameworks are fundamental to the design and analysis of robust RFID systems. In this paper, we develop a new definitional framework for RFID privacy in a rigorous and precise manner. Our framework is based on a zero-knowledge (ZK) formulation [8,6] and incorporates the notions of adaptive completeness and mutual authentication. We provide meticulous justification of the new framework and contrast it with existing ones in the literature. In particular, we prove that our framework is strictly stronger than the ind-privacy model of [18], which answers an open question posed in [18] for developing stronger ...


Side Reactions Of Nitroxide-Mediated Polymerization: N−O Versus O−C Cleavage Of Alkoxyamines, Jennifer L. Hodgson, Luke Roskop, Mark S. Gordon, Ching Yeh Lin, Michelle L. Coote 2010 Australian National University

Side Reactions Of Nitroxide-Mediated Polymerization: N−O Versus O−C Cleavage Of Alkoxyamines, Jennifer L. Hodgson, Luke Roskop, Mark S. Gordon, Ching Yeh Lin, Michelle L. Coote

Chemistry Publications

Free energies for the homolysis of the NO−C and N−OC bonds were compared for a large number of alkoxyamines at 298 and 393 K, both in the gas phase and in toluene solution. On this basis, the scope of the N−OC homolysis side reaction in nitroxide-mediated polymerization was determined. It was found that the free energies of NO−C and N−OC homolysis are not correlated, with NO−C homolysis being more dependent upon the properties of the alkyl fragment and N−OC homolysis being more dependent upon the structure of the aminyl fragment. Acyclic alkoxyamines and ...


Genetic Analysis Of The Federally Endangered Winged Mapleleaf Mussel To Aid Proposed Re-Introduction Efforts, Kevin J. Roe 2010 Iowa State University

Genetic Analysis Of The Federally Endangered Winged Mapleleaf Mussel To Aid Proposed Re-Introduction Efforts, Kevin J. Roe

Kevin J. Roe

The winged mapleleaf, Quadrula fragosa, historically occurred in the Mississippi, Tennessee, Ohio, and Cumberland river drainages, but has suffered severe population and range reductions. At the time that the species was federally listed as endangered, its range was thought to have been reduced to a stretch of the St. Croix River between northwestern Wisconsin and east-central Minnesota. Recently, morphologically “Q. fragosa-like” specimens were discovered at sites in Arkansas (Ouachita River and Saline River), Missouri (Bourbeuse River), and Oklahoma (Little River). Subsequently, a plan was proposed to re-introduce Q. fragosa into portions of its historic range where its been extirpated from ...


Patterns In Rotating Rayleigh–Bénard Convection At High Rotation Rates, Janet Scheel, P. Mutyaba, T. Kimmel 2010 Occidental College

Patterns In Rotating Rayleigh–Bénard Convection At High Rotation Rates, Janet Scheel, P. Mutyaba, T. Kimmel

Janet D. Scheel

We present the results from numerical and theoretical investigations of rotating Rayleigh–Bénard convection for relatively large dimensionless rotation rates, 170 < Ω < 274, and a Prandtl number of 6.4. Unexpected square patterns were found experimentally by Bajaj et al. (Phys. Rev. Lett., vol. 81, 1998, p. 806) in this parameter regime and near threshold for instability in the bulk. These square patterns have not yet been understood theoretically. Sánchez-Álvarez et al. (Phys. Rev. E, vol. 72, 2005, p. 036307) have found square patterns in numerical simulations for similar parameters when only the Coriolis force is included. We performed detailed ...


Probabilistic Model-Based Diagnosis: An Electrical Power System Case Study, Ole Mengshoel, Mark Chavira, Keith Cascio, Adnan Darwiche, Scott Poll, Serdar Uckun 2010 Carnegie Mellon University

Probabilistic Model-Based Diagnosis: An Electrical Power System Case Study, Ole Mengshoel, Mark Chavira, Keith Cascio, Adnan Darwiche, Scott Poll, Serdar Uckun

Ole J Mengshoel

We present in this paper a case study of the probabilistic approach to model-based diagnosis. Here, the diagnosed system is a real-world electrical power system (EPS), i.e., the Advanced Diagnstic and Prognostic Testbed (ADAPT) located at the NASA Ames Research Center. Our probabilistic approach is formally well founded and based on Bayesian networks (BNs) and arithmetic circuits (ACs). We pay special attention to meeting two of the main challenges often associated with real-world application of model-based diagnosis technologies: model development and real-time reasoning. To address the challenge of model development, we develop a systematic approach to representing EPSs as ...


Frequency Dependence In The Initiation Of Laser-Induced Damage, Jeremy Gulley 2010 Kennesaw State University

Frequency Dependence In The Initiation Of Laser-Induced Damage, Jeremy Gulley

Jeremy R. Gulley

Numerous studies have investigated the role of photoionization in ultrafast laser-induced damage of bulk dielectrics. This study examines the role of spectral width and instantaneous laser frequency in laser-induced damage using a frequency dependent multiphoton ionization model and numerical simulation of an 800 nm laser pulse propagating through fused silica. When the individual photon wavelengths are greater than 827 nm, an additional photon is required for photoionization, reducing the probability of the event by many orders of magnitude. Simulation results suggest that this frequency dependence may significantly affect the processes of laser-induced damage and filamentation.


Network Analysis Of Scientific Workflows: A Gateway To Reuse, Wei Tan, Jia Zhang, Ian Foster 2010 Carnegie Mellon University, Silicon Valley

Network Analysis Of Scientific Workflows: A Gateway To Reuse, Wei Tan, Jia Zhang, Ian Foster

Jia Zhang

No abstract provided.


Particulate Pictures And Kinetic-Molecular Theory Concepts: Seizing An Opportunity, Mark Waner 2010 John Carroll University

Particulate Pictures And Kinetic-Molecular Theory Concepts: Seizing An Opportunity, Mark Waner

Mark J. Waner

This work examines commonly used particulate-level pictures meant to illustrate gases. These pictures are found throughout textbooks in the middle grades through the college level, as well as in questions frequently used to assess conceptual learning in students. This work uses the kinetic-molecular theory of gases to demonstrate the inaccuracies often present in these figures, which offers the opportunity to address model limitations to students and to develop better pictures. A basis for using these pictures to discuss models and ideas for ways these pictures can be used for inquiry activities based on analysis of scales is also discussed.


Kinetic And Mechanistic Studies Of The Deuterium Exchange In Classical Keto−Enol Tautomeric Equilibrium Reactions, Michael Nichols, Mark Waner 2010 John Carroll University

Kinetic And Mechanistic Studies Of The Deuterium Exchange In Classical Keto−Enol Tautomeric Equilibrium Reactions, Michael Nichols, Mark Waner

Mark J. Waner

An extension of the classic keto−enol tautomerization of β-dicarbonyl compounds into a kinetic analysis of deuterium exchange is presented. It is shown that acetylacetone and ethyl acetoacetate undergo nearly complete deuterium exchange of the α-methylene carbon when dissolved in methanol-d4. The extent of deuteration may be monitored via NMR spectroscopy as a function of time. A mechanism for deuterium exchange is presented and shown to be consistent with a consecutive first-order process. The data for acetylacetone are consistent with steady-state kinetics, whereas those of ethyl acetoacetate illustrate nonsteady-state behavior, offering an accessible example where students might collect and analyze ...


Background Fluorescence In Groundwater From A Tropical Karst Island Aquifer, Michelle Hoffman 2010 University of South Florida

Background Fluorescence In Groundwater From A Tropical Karst Island Aquifer, Michelle Hoffman

Michelle Hoffman

Background levels of four fluorescent compounds were monitored biweekly at thirteen sampling sites on Guam, consisting of subtidal and intertidal springs, dissolution fractures, and internal upland contact spring discharge, over a 13-month period from 2006 to 2007. Samples were compared to local precipitation and to seawater samples from four nearby reef flats. The data revealed that the concentrations of optical brighteners were consistently two orders of magnitude greater than either sodium fluorescein or rhodamine WT, while Eosine Y was rarely detected. Background levels in seawater, by comparison, accounted for 25% or more of the fluorescent compounds detected at the thirteen ...


Product Quality, Perceived Price And Product Features Analysis And Their Influences To Brand Image And Consumer Satisfaction, 2010 Selected Works

Product Quality, Perceived Price And Product Features Analysis And Their Influences To Brand Image And Consumer Satisfaction

Benjamin L. Harwood

Homa Posniroha Harahap, 2010; Product Quality, Perceived Price and Product Features Analysis and Their Influences to Brand Image and Consumer Satisfaction. Counsellor ; DR. Mohamad Rizan, SE., MM. Generally, the purpose of the research are: 1) Analyzing product quality, perceived price and product features and their influences to brand image and consumer satisfaction, 2) Testing hypothesis on relationship between product quality, perceived price and product features and their influences to brand image and consumer satisfaction,3) Testing hypothesis product quality, perceived price, product features and their direct influences or through brand image to consumer satisfaction. Unit of analysis are mobile phone ...


Planetary-Scale Rfid Services In An Age Of Uberveillance, K. Michael, George Roussos, George Q. Huang, Rajit Gadh, Arunabh Chattopadhyay, S Prabhu, Peter Chu 2010 University of Wollongong

Planetary-Scale Rfid Services In An Age Of Uberveillance, K. Michael, George Roussos, George Q. Huang, Rajit Gadh, Arunabh Chattopadhyay, S Prabhu, Peter Chu

Professor Katina Michael

Radio-frequency identification has a great number of unfulfilled prospects. Part of the problem until now has been the value proposition behind the technology- it has been marketed as a replacement technique for the barcode when the reality is that it has far greater capability than simply non-line-of-sight identification, towards decision-making in strategic management and reengineered business processes. The vision of the Internet of Things has not eventuated but a world in which every object you can see around you carries the possibility of being connected to the internet is still within the realm of possibility. However incremental innovations may see ...


A Web 2.0-Based Collaborative Annotation System For Enhancing Knowledge Sharing In Collaborative Learning Environments, Addison Y.S. Su, Stephen J.H. Yang, Jia Zhang, W.Y. Hwang 2010 Carnegie Mellon University, Silicon Valley

A Web 2.0-Based Collaborative Annotation System For Enhancing Knowledge Sharing In Collaborative Learning Environments, Addison Y.S. Su, Stephen J.H. Yang, Jia Zhang, W.Y. Hwang

Jia Zhang

No abstract provided.


Physical Basis Of The Inducer-Dependent Cooperativity Of The Central Glycolytic Genes Repressor/Dna Complex, Denis Chaix, Matthew L. Ferguson, Cedric Atmanene, Alain Van Dorsselaer, Sarah Sanglier-Cianférani, Catherine A. Royer, Nathalie Declerck 2010 Boise State University

Physical Basis Of The Inducer-Dependent Cooperativity Of The Central Glycolytic Genes Repressor/Dna Complex, Denis Chaix, Matthew L. Ferguson, Cedric Atmanene, Alain Van Dorsselaer, Sarah Sanglier-Cianférani, Catherine A. Royer, Nathalie Declerck

Matthew L. Ferguson

The Central glycolytic genes Repressor (CggR) from Bacillus subtilis belongs to the SorC family of transcription factors that control major carbohydrate metabolic pathways. Recent studies have shown that CggR binds as a tetramer to its tandem operator DNA sequences and that the inducer metabolite, fructose 1,6-bisphosphate (FBP), reduces the binding cooperativity of the CggR/DNA complex. Here, we have determined the effect of FBP on the size, shape and stoichiometry of CggR complexes with full-length and half-site operator sequence by small-angle X-ray scattering, size-exclusion chromatography, fluorescence cross-correlation spectroscopy and noncovalent mass spectrometry (MS). Our results show that CggR forms ...


Enhancing Stockmarket Trading Performance With Anns, Bruce Vanstone, Gavin Finnie 2010 Bond University

Enhancing Stockmarket Trading Performance With Anns, Bruce Vanstone, Gavin Finnie

Bruce Vanstone

Artificial Neural Networks (ANNs) have been repeatedly and consistently applied to the domain of trading financial time series, with mixed results. Many researchers have developed their own techniques for both building and testing such ANNs, and this presents a difficulty when trying to learn lessons and compare results. In a previous paper, Vanstone and Finnie have outlined an empirical methodology for creating and testing ANNs for use within stockmarket trading systems. This paper demonstrates the use of their methodology, and creates and benchmarks a financially viable ANN-based trading system. Many researchers appear to fail at the final hurdles in their ...


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