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A Unified Theory Of Function Spaces And Hyperspaces: Local Properties, Szymon Dolecki, Frédéric D. Mynard 2010 Burgundy University

A Unified Theory Of Function Spaces And Hyperspaces: Local Properties, Szymon Dolecki, Frédéric D. Mynard

Mathematical Sciences Faculty Publications

Many classically used function space structures (including the topology of pointwise convergence, the compact-open topology, the Isbell topology and the continuous convergence) are induced by a hyperspace structure counterpart. This scheme is used to study local properties of function space structures on C(X,R), such as character, tighntess, fan-tightness, strong fan-tightness, the Fr{\'e}chet property and some of its variants. Under mild conditions, local properties of C(X,R) at the zero function correspond to the same property of the associated hyperspace structure at X. The latter is often easy to characterize in terms of covering properties of ...


A History Of Computer Technology And Its Impact On Academics At Suny Brockport, Thomas L. Jennings 2010 The College at Brockport

A History Of Computer Technology And Its Impact On Academics At Suny Brockport, Thomas L. Jennings

History Master's Theses

A history of academic computing at SUNY Brockport; while administrative computing shares some common history but is only examined here in the broader context of academic computing capability; their histories occasionally intertwine but are distinct.

The history of SUNY Brockport's management of the academic computing revolution containing success stories and shortcomings; It is presented in decades starting with the 1960s when computer technology was not an essential part of the campus and ends in the 21st century when computers are an integral part of the campus.


Comparative Efficacy Versus Effectiveness Of Initial Antiretroviral Therapy In Clinical Trials Versus Routine Care, Justin S. Routman, James H. Willig, Andrew O. Westfall, Sarah R. Abroms, Mohit Varshney, Sunil Adusumilli, Jeroan J. Allison, Karen G. Savage, Michael S. Saag, Michael J. Mugavero 2010 University of Alabama at Birmingham

Comparative Efficacy Versus Effectiveness Of Initial Antiretroviral Therapy In Clinical Trials Versus Routine Care, Justin S. Routman, James H. Willig, Andrew O. Westfall, Sarah R. Abroms, Mohit Varshney, Sunil Adusumilli, Jeroan J. Allison, Karen G. Savage, Michael S. Saag, Michael J. Mugavero

Quantitative Health Sciences Publications and Presentations

BACKGROUND: The applicability of clinical trial findings (efficacy) to the routine care setting (effectiveness) may be limited because of study eligibility criteria and volunteer bias. Although well-chronicled in many conditions, the efficacy versus effectiveness of antiretroviral therapy (ART) remains understudied.

METHODS: A retrospective study of the University of Alabama at Birmingham 1917 Clinic Cohort evaluated ART-naive patients who started ART from 1 January 2000 through 31 December 2006. Patients received ART through clinical trials or routine care. Multivariable logistic and linear regression models were fit to evaluate factors associated with virological failure (virological failure was defined as a viral load ...


Oxygen Regulates The Effective Diffusion Distance Of Nitric Oxide In The Aortic Wall, Xiaoping Liu, Parthasarathy Srinivasan, Eric Collard, Paula Grajdeanu, Kevin Lok, Sarah E. Boyle, Avner Friedman, Jay L. Zweier 2010 Ohio State University

Oxygen Regulates The Effective Diffusion Distance Of Nitric Oxide In The Aortic Wall, Xiaoping Liu, Parthasarathy Srinivasan, Eric Collard, Paula Grajdeanu, Kevin Lok, Sarah E. Boyle, Avner Friedman, Jay L. Zweier

Mathematics Faculty Publications

Endothelium-derived nitric oxide (NO) is critical in maintaining vascular tone. Accumulating evidence shows that NO bioavailability is regulated by oxygen concentration. However, it is unclear to what extent the oxygen concentration regulates NO bioavailability in the vascular wall. In this study, a recently developed experimental setup was used to measure the NO diffusion flux across the aortic wall at various oxygen concentrations. It was observed that for a constant NO concentration at the endothelial surface, the measured NO diffusion flux out of the adventitial surface at [O2] = 0 μM is around fivefold greater than at [O2] = 150 μM, indicating that ...


Potential Driven Deposition Of Polyelectrolytes Onto The Surface Of Cysteine Monolayers Assembled On Gold, Wesley Sanders, Mark Anderson 2010 Virginia Polytechnic Institute and State University

Potential Driven Deposition Of Polyelectrolytes Onto The Surface Of Cysteine Monolayers Assembled On Gold, Wesley Sanders, Mark Anderson

Mark R. Anderson

Electrochemical impedance spectroscopy and the quartz crystal microbalance measurements are used to examine the ability of potential applied to a substrate to create, in situ, conditions favorable for the electrostatic deposition of polyelectrolytes onto a gold substrate modified by the self-assembly of cysteine. Cysteine is a zwitterionic compound that, when confined to a substrate, has the ability to establish either a net positive or a net negative interfacial charge, depending on the conditions. As such, cysteine modified interfaces could possibly be used as a versatile substrate for deposition of either cationic or anionic polyelectrolytes. The potential of zero charge of ...


Synthesis And Characterization Of Allylic Dinuclear Molybdenum Complexes With Bridging Oxygen And Sulfur Containing Ligands., Mazin Shatnawi, Samer Tanash, Saleem Al-Ahmad, Paul Challen, Gerald Henkel 2010 John Carroll University

Synthesis And Characterization Of Allylic Dinuclear Molybdenum Complexes With Bridging Oxygen And Sulfur Containing Ligands., Mazin Shatnawi, Samer Tanash, Saleem Al-Ahmad, Paul Challen, Gerald Henkel

Paul R. Challen

No abstract provided.


Electrically Switched Color With Polymer-Stabilized Blue-Phase Liquid Crystals, Shin-Ying Lu, Liang-Chy Chien 2010 Kent State University - Kent Campus

Electrically Switched Color With Polymer-Stabilized Blue-Phase Liquid Crystals, Shin-Ying Lu, Liang-Chy Chien

Liang-Chy Chien

We report an electrical-field switched color device using a polymer-stabilized blue-phase ( PSBP) liquid crystal in which the Bragg-reflected color of the blue phase ( BP) can be switched to reflect a second color. The phase-separated three-dimensional polymer network transcribes the cubic structure of a BP liquid crystal and restrains the deformation of cubic lattice by the external electric field. The new wide-range electric-field switched colors with PSBP may be an important step toward ecofriendly color reflective displays. (C) 2010 Optical Society of America


Evaluation And Development Of Selection Criteria To Guide Organizational Selection Of A Project Management Maturity Model, Diane Zandin 2010 Regis University

Evaluation And Development Of Selection Criteria To Guide Organizational Selection Of A Project Management Maturity Model, Diane Zandin

All Regis University Theses

Organizations wishing to measurably and continuously improve processes often look towards maturity models, such as OPM3 and CMMI, as their panacea. However, selecting the wrong model for the organizations goals and resources can result in project failure. This study, focusing on OPM3 and CMMI, proposes a guidance tool that can help organizations select the right maturity model. The study is framed in the state government context due to the complexity and relative insularity of that environment. In addition to being a limited based, state governments have several limiters that factor into project selection, namely budget and taxpayer transparency. Using several ...


A Note On Empirical Sample Distribution Of Journal Impact Factors In Major Discipline Groups, Sudhanshu Mishra 2010 North-Eastern Hill University, Shillong (India)

A Note On Empirical Sample Distribution Of Journal Impact Factors In Major Discipline Groups, Sudhanshu Mishra

Sudhanshu K Mishra

What type of statistical distribution do the Journal Impact Factors follow? In the past, researchers have hypothesized various types of statistical distributions underlying the generation mechanism of journal impact factors. These are: lognormal, normal, approximately normal, Weibull, negative exponential, combination of exponentials, Poisson, Generalized inverse Gaussian-Poisson, negative binomial, generalized Waring, gamma, etc. It is pertinent to note that the major characteristics of JIF data lay in the asymmetry and non-mesokurticity. The present study, frequently encounters Burr-XII, inverse Burr-III (Dagum), Johnson SU, and a few other distributions closely related to Burr distributions to best fit the JIF data in subject groups ...


The Power Of The Weak: Recognition Of Ion Pairs In Water Using A Simple Array Sensor, Yuan-li Liu, Manuel Palacios, Pavel Anzenbacher 2010 Bowling Green State University

The Power Of The Weak: Recognition Of Ion Pairs In Water Using A Simple Array Sensor, Yuan-Li Liu, Manuel Palacios, Pavel Anzenbacher

Pavel Anzenbacher

An array sensor comprising six off-the-shelf indicators doped in a poly(ether-urethane) recognizes five cations, seven anions and thirty-five ion pairs at pH 5-9 in water. Such a discrimination capacity and recognition efficiency (6:35) with >= 93% accuracy is rare. Low cost and wide availability of various polymers and indicators could make this approach useful in numerous applications.


A Journey On Wave: Comparing Wave Energy Generation In China And In The U.S., Yao Yin 2010 Oregon State University

A Journey On Wave: Comparing Wave Energy Generation In China And In The U.S., Yao Yin

Yao Yin

This research aims to present a snapshot of wave energy development in China and in the U.S. with respect to wave energy resource, energy assessment zoning, technology types, partnership model in developing wave energy, designated wave energy organizations, policy in place, and social acceptance. The methodology of this research is based on literature review from a comparative perspective. Conclusions drawn can inform and benefit wave energy development on both sides.


Nonparametric Estimation Of The Case Fatality Ratio With Competing Risks Data: An Application To Severe Acute Respiratory Syndome (Sars) , Nicholas Jewell, Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, A. J. Hedley 2010 Division of Biostatistics, School of Public Health, University of California, Berkeley

Nonparametric Estimation Of The Case Fatality Ratio With Competing Risks Data: An Application To Severe Acute Respiratory Syndome (Sars) , Nicholas Jewell, Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, A. J. Hedley

Nicholas P. Jewell

For diseases with some level of associated mortality, the case fatality ratio measures the proportion of diseased individuals who die from the disease. In principle, it is straightforward to estimate this quantity from individual follow-up data that provides times from onset to death or recovery. In particular, in a competing risks context, the case fatality ratio is defined by the limiting value of the sub-distribution function, associated with death, at infinity. When censoring is present, however, estimation of this quantity is complicated by the possibility of little information in the right tail of of the sub-distribution function, requiring use of ...


Analyzing Direct Effects In Randomized Trials With Secondary Interventions , Michael Rosenblum, Nicholas Jewell, Mark van der Laan, Stephen Shiboski, Ariane van der Straten, Nancy Padian 2010 Division of Biostatistics, School of Public Health, University of California, Berkeley

Analyzing Direct Effects In Randomized Trials With Secondary Interventions , Michael Rosenblum, Nicholas Jewell, Mark Van Der Laan, Stephen Shiboski, Ariane Van Der Straten, Nancy Padian

Nicholas P. Jewell

The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized trial that investigated the effect of diaphragm and lubricant gel use in reducing HIV infection among susceptible women. 5,045 women were randomly assigned to either the active treatment arm or not. Additionally, all subjects in both arms received intensive condom counselling and provision, the "gold standard" HIV prevention barrier method. There was much lower reported condom use in the intervention arm than in the control arm, making it difficult to answer important public health questions based solely on the intention-to-treat analysis. We adapt an ...


Maximum Likelihood Estimation Of Ordered Multinomial Parameters , Nicholas Jewell, Jack Kalbfleisch 2010 University of California, Berkley

Maximum Likelihood Estimation Of Ordered Multinomial Parameters , Nicholas Jewell, Jack Kalbfleisch

Nicholas P. Jewell

The pool-adjacent violator-algorithm (Ayer et al., 1955) has long been known to give the maximum likelihood estimator of a series of ordered binomial parameters, based on an independent observation from each distribution (see, Barlow et al., 1972). This result has immediate application to estimation of a survival distribution based on current survival status at a set of monitoring times. This paper considers an extended problem of maximum likelihood estimation of a series of ‘ordered’ multinomial parameters pi = (p1i, p2i, . . . , pmi) for 1 < = I < = k, where ordered means that pj1 < = pj2 < = .. . < = pjk for each j with 1 < = j < = m-1. The data consist of k independent observations X1, . . . ,Xk where Xi has a multinomial distribution with probability parameter pi and known index ni > = 1. By making use of variants of the pool adjacent violator algorithm, we obtain a simple algorithm to ...


Detailed Version: Analyzing Direct Effects In Randomized Trials With Secondary Interventions: An Application To Hiv Prevention Trials, Michael Rosenblum, Nicholas Jewell, Mark van der Laan, Stephen Shiboski, Ariane van der Straten, Nancy Padian 2010 University of California, Berkeley

Detailed Version: Analyzing Direct Effects In Randomized Trials With Secondary Interventions: An Application To Hiv Prevention Trials, Michael Rosenblum, Nicholas Jewell, Mark Van Der Laan, Stephen Shiboski, Ariane Van Der Straten, Nancy Padian

Nicholas P. Jewell

This is the detailed technical report that accompanies the paper “Analyzing Direct Effects in Randomized Trials with Secondary Interventions: An Application to HIV Prevention Trials” (an unpublished, technical report version of which is available online at http://www.bepress.com/ucbbiostat/paper223). The version here gives full details of the models for the time-dependent analysis, and presents further results in the data analysis section. The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized trial that investigated the effect of diaphragm and lubricant gel use in reducing HIV infection among susceptible women. 5,045 women ...


Regression Analysis Of A Disease Onset Distribution Using Diagnosis Data, Jessica Young, Nicholas Jewell, Steven Samuels 2010 University of California, Berkeley

Regression Analysis Of A Disease Onset Distribution Using Diagnosis Data, Jessica Young, Nicholas Jewell, Steven Samuels

Nicholas P. Jewell

We consider methods for estimating the effect of a covariate on a disease onset distribution when the observed data structure consists of right-censored data on diagnosis times and current status data on onset times amongst individuals who have not yet been diagnosed. Dunson and Baird (2001) approached this problem using maximum likelihood, under the assumption that the ratio of the diagnosis and onset distributions is monotonic non-decreasing. As an alternative, we propose a two-step estimator, an extension of the approach of van der Laan, Jewell and Petersen (1997) in the single sample setting, that is computationally much simpler and requires ...


A Machine-Learning Algorithm For Estimating And Ranking The Impact Of Environmental Risk Factors In Exploratory Epidemiological Studies, Jessica Young, Alan Hubbard, B Eskenazi, Nicholas Jewell 2010 Harvard School of Public Health

A Machine-Learning Algorithm For Estimating And Ranking The Impact Of Environmental Risk Factors In Exploratory Epidemiological Studies, Jessica Young, Alan Hubbard, B Eskenazi, Nicholas Jewell

Nicholas P. Jewell

No abstract provided.


Dynamics Of A Liquid-Crystal Variable Optical Prism Based On Pancharatnam Phase, Lei Shi, Paul McManamon, Douglas Bryant, Ke Zhang, Philip Bos 2010 Kent State University - Kent Campus

Dynamics Of A Liquid-Crystal Variable Optical Prism Based On Pancharatnam Phase, Lei Shi, Paul Mcmanamon, Douglas Bryant, Ke Zhang, Philip Bos

Philip J. Bos

We consider the dynamics of a variable optical prism based on Pancharatnam phase. The device basics, using liquid crystals (LCs) as the electro-optical material, have been previously proposed. In this paper, we study the dynamics of discrete changes in the phase profile, and also continuous changes in the phase profile through acquired data and numerical modeling. We show that a design based on LCs whose dielectric anisotropy can change sign (as a function of frequency) allows continuous tuning with reasonable response times.


Non-Abelian Black Holes In D = 5 Maximal Gauged Supergravity, Mirjam Cvetič, H. Lü, C. N. Pope 2010 University of Pennsylvania

Non-Abelian Black Holes In D = 5 Maximal Gauged Supergravity, Mirjam Cvetič, H. Lü, C. N. Pope

Department of Physics Papers

We investigate static non-Abelian black hole solutions of anti–de Sitter (AdS) Einstein-Yang-Millsdilaton gravity, which is obtained as a consistent truncation of five-dimensional maximal gauged supergravity. If the dilaton is (consistently) set to zero, the remaining equations of motion, with a spherically-symmetric ansatz, may be derived from a superpotential. The associated first-order equations admit an explicit solution supported by a non-Abelian SU(2) gauge potential, which has a logarithmically growing mass term. In an extremal limit the horizon geometry becomes AdS2 X S3. If the dilaton is also excited, the equations of motion cannot easily be solved explicitly ...


Conservation Implications Of Distinct Genetic Structuring In The Endangered Freshwater Fish Nannoperca Oxleyana (Percichthyidae), James Knight, Catherine Nock, Martin Elphinstone, Peter Baverstock 2010 Southern Cross University

Conservation Implications Of Distinct Genetic Structuring In The Endangered Freshwater Fish Nannoperca Oxleyana (Percichthyidae), James Knight, Catherine Nock, Martin Elphinstone, Peter Baverstock

Martin S Elphinstone

The maintenance of genetic diversity and gene flow in threatened species is a vital consideration for recovery programs. The endangered Oxleyan pygmy perch Nannoperca oxleyana has a fragmented distribution within coastal freshwater drainages of southern Queensland and northern New South Wales, Australia. In the present study, mitochondrial DNA control region variation was used to assess genetic diversity and structure across the geographical range of this species. Haplotypic diversity was highest in a small NSW subcatchment south of Evans Head (h = 0.594) followed by Marcus Creek in Queensland (h = 0.475). Distinct genetic differentiation was evident among the Queensland localities ...


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