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Acth Enhances Lipid Accumulation In Bone-Marrow Derived Mesenchymal Stem Cells Undergoing Adipogenesis, Jodi F. Evans Ph.D., Thomas Rhodes, Michelle Pazienza 2018 Molloy College

Acth Enhances Lipid Accumulation In Bone-Marrow Derived Mesenchymal Stem Cells Undergoing Adipogenesis, Jodi F. Evans Ph.D., Thomas Rhodes, Michelle Pazienza

Jodi Evans

ACTH is a major hormone of the stress axis or hypothalamic-pituitary-adrenal (HPA) axis. It is derived from pro-opiomelanocortin (POMC) the precursor to the melanocortin family of peptides. POMC produces the biologically active melanocortin peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and β-endorphin. The melanocortin system plays an imperative role in energy expenditure, insulin release and insulin sensitivity. Bone marrow derived mesenchymal stem cells circulate in the blood stream and as progenitor cells have the potential to differentiate into many cell types such as osteoblasts, chondrocytes and adipocytes. Here we ...


Adrenocorticotropin Hormone Expression In The Developing Chicken Limb, Jodi F. Evans Ph.D., Michelle Vigliotti 2018 Molloy College

Adrenocorticotropin Hormone Expression In The Developing Chicken Limb, Jodi F. Evans Ph.D., Michelle Vigliotti

Jodi Evans

In previous studies using mammalian models we have found both clinical and laboratory evidence of a role for melanocortins in endochondral ossification. The melanocortin system has remarkable conservation among vertebrates and melanocortin receptors are expressed with significant sequence homology in teleosts to mammals. The overall goal of these studies is to provide a more accessible model of melanocortin involvement in endochondral growth. We hope to determine if melanocortins play a role during endochondral ossification of the developing chicken limb. Like in mammals melanocortins are widely distributed throughout the body of chicken and participate in a wide range of physiological functions ...


Cd105 Deficieny In Mouse Aorta-Derived Mesenchymal Stem Cells Promotes An Enhanced Inflammatory Response To Lipolysaccharide., Jodi F. Evans Ph.D., Joseph Granata, Hugo Sanchez, Philip Loeschinger, Anthony Goez 2018 Molloy College

Cd105 Deficieny In Mouse Aorta-Derived Mesenchymal Stem Cells Promotes An Enhanced Inflammatory Response To Lipolysaccharide., Jodi F. Evans Ph.D., Joseph Granata, Hugo Sanchez, Philip Loeschinger, Anthony Goez

Jodi Evans

Mesenchymal stem cells (MSCs) are being widely studied for their ability to regulate macrophage cell responses. Previous works have demonstrated that mouse aorta-derived MSC (mAo-MSC) support the macrophage inflammatory response. mAo-MSC have been characterized phenotypically for MSC-associated surface antigens and express CD90 and CD105 but do not express CD73. CD105, also known as endoglin, is a coreceptor in the TGFβ superfamily of receptors. Mouse adipose-derived MSC lacking CD105 have an increased capacity to regulate T-cells by reducing their proliferation while elevated CD105 expression is consistently associated with inflammatory disease. Therefore, we hypothesized that suppression of CD105 in mAo-MSC will reduce ...


Does Stress Make You Fat?, Jodi F. Evans Ph.D., Thomas Rhodes, Michelle Pazienza, Catherine Nunez 2018 Molloy College

Does Stress Make You Fat?, Jodi F. Evans Ph.D., Thomas Rhodes, Michelle Pazienza, Catherine Nunez

Jodi Evans

ACTH is a major hormone of the stress axis or hypothalamic-pituitary-adrenal (HPA) axis. It is derived from pro-opiomelanocortin (POMC) the precursor to the melanocortin family of peptides. POMC produces the biologically active melanocortin peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and β-endorphin. The melanocortin system plays an imperative role in energy expenditure, insulin release and insulin sensitivity. Bone marrow derived mesenchymal stem cells circulate in the blood stream and as progenitor cells have the potential to differentiate into many cell types such as osteoblasts, chondrocytes and adipocytes. Here we ...


A Quest For A Custom-Made Mesenchymal Stem Cell In The Treatment Of Inflammatory Diseases, Jodi F. Evans Ph.D., Natalie Fernandez, Caroline Winters, Maria Barandica, Abi Ocava, Michael Delsignore, Kristina Coppola 2018 Molloy College

A Quest For A Custom-Made Mesenchymal Stem Cell In The Treatment Of Inflammatory Diseases, Jodi F. Evans Ph.D., Natalie Fernandez, Caroline Winters, Maria Barandica, Abi Ocava, Michael Delsignore, Kristina Coppola

Jodi Evans

Mesenchymal stem cells (MSC) are multipotent cells that can differentiate into adipocytes, osteoblasts and chondrocytes. These cells are widely studied in tissue regeneration and for their therapeutic effects in inflammatory disease. MSC interact with cells of the innate and adaptive immunity to promote or suppress the inflammatory response. MSC from the bone marrow (D1 MSC) decrease inflammatory responses by lowering macrophage (Mᶲ) secretion of soluble factors such as nitric oxide (NO), interleukin-12 (IL-12) and tumor necrosis factor-α (TNFα). Aorta-derived MSC (mAo MSC) support the macrophage inflammatory response by contributing to NO secretion and enhancing secretion of TNFα by Mᶲ. Previous ...


Using An Instrumented Drone To Probe Dust Devils On Oregon’S Alvord Desert, Brian Jackson, Ralph Lorenz, Karan Davis, Brock Lipple 2018 Boise State University

Using An Instrumented Drone To Probe Dust Devils On Oregon’S Alvord Desert, Brian Jackson, Ralph Lorenz, Karan Davis, Brock Lipple

Brian Jackson

Dust devils are low-pressure, small (many to tens of meters) convective vortices powered by surface heating and rendered visible by lofted dust. Dust devils occur ubiquitously on Mars, where they may dominate the supply of atmospheric dust, and since dust contributes significantly to Mars’ atmospheric heat budget, dust devils probably play an important role in its climate. The dust-lifting capacity of a devil likely depends sensitively on its structure, particularly the wind and pressure profiles, but the exact dependencies are poorly constrained. Thus, the exact contribution to Mars’ atmosphere remains unresolved. Analog studies of terrestrial devils have provided some insights ...


Cosmic Ray Muons In The Standard Model Of Fundamental Particles, Angel Gutarra-Leon, Jorge Del Carpio Arispe, Cioli Barazandeh, Walerian Majewski 2018 George Mason University

Cosmic Ray Muons In The Standard Model Of Fundamental Particles, Angel Gutarra-Leon, Jorge Del Carpio Arispe, Cioli Barazandeh, Walerian Majewski

Exigence

Muons are one of the twelve fundamental particle types of matter, having relatively long free-particle lifetime. A muon decays into three other light particles (leptons) through action of the “weak” force, transmitted by the so-called “heavy photons” - bosons W+/W-. Muons are present in the secondary cosmic ray showers in the atmosphere and reach the sea level. By detecting the delay time between arrival of the muon and an appearance of the decay electron in our single scintillation detector, we measured the muon’s average lifetime at rest in the material of our detector. This compares well with the established ...


Edos: Edge Assisted Offloading System For Mobile Devices, Hank H. Harvey, Ying Mao, Yantian Hou, Bo Sheng 2018 College of New Jersey

Edos: Edge Assisted Offloading System For Mobile Devices, Hank H. Harvey, Ying Mao, Yantian Hou, Bo Sheng

Yantian Hou

Offloading resource-intensive jobs to the cloud and nearby users is a promising approach to enhance mobile devices. This paper investigates a hybrid offloading system that takes both infrastructure-based networks and Ad-hoc networks into the scope. Specifically, we propose EDOS, an edge assisted offloading system that consists of two major components, an Edge Assistant (EA) and Offload Agent (OA). EA runs on the routers/towers to manage registered remote cloud servers and local service providers and OA operates on the users’ devices to discover the services in proximity. We present the system with a suite of protocols to collect the potential ...


A Graphical Digital Personal Assistant That Grounds And Learns Autonomously, Casey Kennington, Aprajita Shukla 2018 Boise State University

A Graphical Digital Personal Assistant That Grounds And Learns Autonomously, Casey Kennington, Aprajita Shukla

Casey R. Kennington

We present a speech-driven digital personal assistant that is robust despite little or no training data and autonomously improves as it interacts with users. The system is able to establish and build common ground between itself and users by signaling understanding and by learning a mapping via interaction between the words that users actually speak and the system actions. We evaluated our system with real users and found an overall positive response. We further show through objective measures that autonomous learning improves performance in a simple itinerary filling task.


Coms: Customer Oriented Migration Service, Kai Huang, Xing Gao, Fengwei Zhang, Jidong Xiao 2018 Boise State University

Coms: Customer Oriented Migration Service, Kai Huang, Xing Gao, Fengwei Zhang, Jidong Xiao

Jidong Xiao

Virtual machine live migration has been studied for more than a decade, and this technique has been implemented in various commercial hypervisors. However, currently in the cloud environment, virtual machine migration is initiated by system administrators. Cloud customers have no say on this: They can not initiate a migration, and they do not even know whether or not their virtual machines have been migrated. In this paper, we propose the COMS framework, which is short for "Customer Oriented Migration Service". COMS gives more control to cloud customers so that migration becomes a service option and customers are more aware of ...


Muang Rae Geothermal System: Drilling And Borehole Geophysics, 1000-M Core Hole Into Granitic Rock, Amphoe Pai, Mae Hong Son Province, Northern Thailand, Spencer H. Wood, Kriangsak Pirarai, Aranya Fuangswasdi, Wiboon Kaentao, Albert Waibel, Fongsaward S. Singharajwarapan 2018 Boise State University

Muang Rae Geothermal System: Drilling And Borehole Geophysics, 1000-M Core Hole Into Granitic Rock, Amphoe Pai, Mae Hong Son Province, Northern Thailand, Spencer H. Wood, Kriangsak Pirarai, Aranya Fuangswasdi, Wiboon Kaentao, Albert Waibel, Fongsaward S. Singharajwarapan

Spencer H. Wood

In 2015, a 1-km core hole was drilled into granitic rock at the Muang Rae geothermal area. Previous drilling in 1993 to 200 m was unsuccessful in obtaining flows, but one of the “dry” wells began flowing in August, 2013 at 9.75 L/s of 96.9°C water from a fracture zone 80 m deep. In the sandy bed of the Pai River, 150 m south of that well is a 600-m long line of hot seeps, oriented NE, with highest temperature measured at 94.5°C. Geology is foliated Triassic (?) granitic rock cut by a NE-SW-trending normal ...


Gphcessay.Docx, Daryl Bagley 2018 Harding University

Gphcessay.Docx, Daryl Bagley

Daryl Bagley

No abstract provided.


Gphcessay.Docx, Daryl Bagley 2018 Harding University

Gphcessay.Docx, Daryl Bagley

Daryl Bagley

No abstract provided.


Greer Studies, Teaches How To Improve Medicines, Aldemaro Romero Jr. 2018 CUNY Bernard M Baruch College

Greer Studies, Teaches How To Improve Medicines, Aldemaro Romero Jr.

Publications and Research

“As a child, I was interested in asking questions. Like why different substances work the way they do and why they have some effect on our bodies. I was fascinated by hydrogen-peroxide and how it decomposes when you pour it on the wound. I would ask why it happens, what is the reason?” That’s how Dr. Edyta Greer explains how she became interested in science. A native of Poland, Greer received her master’s from Warsaw University and her doctorate from the Graduate Center of the City University of New York. Today she is an associate professor in the ...


Physical Models Of The Toroidal Dipole, Armian Hanelli, Amanuel Eshete, Jorge Del Carpio, Walerian Majewski 2018 California Institute of Technology

Physical Models Of The Toroidal Dipole, Armian Hanelli, Amanuel Eshete, Jorge Del Carpio, Walerian Majewski

Exigence

We have investigated two models of the third elementary electromagnetic dipole, known as the toroidal dipole. Its magnetic realization is a circumferentially magnetized ring constructed of neodymium. The electric model of the dipole is a toroidal coil connected to a DC voltage. The electric and magnetic toroids produce only an inner magnetic field, inside the torus, and interact only on contact with the electric current density or when immersed in a time-dependent electric field. We studied the characteristics of a permanent-magnet toroid, and observed the influence of electric and magnetic fields on it. A static toroidal dipole moment of this ...


The Threat Of Artificial Superintelligence, Joseph D. Ebhardt 2018 Lord Fairfax Community College

The Threat Of Artificial Superintelligence, Joseph D. Ebhardt

Exigence

This paper discusses the development of AI and the threat posed by the theoretical achievement of artificial superintelligence. AI is becoming an increasingly significant fixture in our lives and this will only continue in the future. The development of artificial general intelligence (AGI) would quickly lead to artificial superintelligence (ASI). AI researcher Steve Omohundro’s universal drives of rational systems demonstrate why ASI could behave in ways unanticipated by its designers. A technological singularity may occur if AI is allowed to undergo uncontrolled rapid self-improvement, which could pose an extinction-level risk to the human race. Two possible safety measures, AI ...


Remote Sensing Of Seasonal Changes And Disturbances In Mangrove Forest: A Case Study From South Florida, Keqi Zhang, Bina Thapa, Michael S. Ross, Daniel Gann 2018 International Hurricane Research Center and Department of Earth and Environment, Florida International University

Remote Sensing Of Seasonal Changes And Disturbances In Mangrove Forest: A Case Study From South Florida, Keqi Zhang, Bina Thapa, Michael S. Ross, Daniel Gann

Daniel Gann

Knowledge of the spatial and temporal changes caused by episodic disturbances and seasonal variability is essential for understanding the dynamics of mangrove forests at the landscape scale, and for building a baseline that allows detection of the effects of future environmental change. In combination with LiDAR data, we calculated four vegetation indices from 150 Landsat TM images from 1985 to 2011 in order to detect seasonal changes and distinguish them from disturbances due to hurricanes and chilling events in a mangrove-dominated coastal landscape. We found that normalized difference moisture index (NDMI) performed best in identifying both seasonal and event-driven episodic ...


Algebraic Methods For The Construction Of Algebraic-Difference Equations With Desired Behavior, Lazaros Moysis, Nicholas Karampetakis 2018 Aristotle University of Thessaloniki

Algebraic Methods For The Construction Of Algebraic-Difference Equations With Desired Behavior, Lazaros Moysis, Nicholas Karampetakis

Electronic Journal of Linear Algebra

For a given system of algebraic and difference equations, written as an Auto-Regressive (AR) representation $A(\sigma)\beta(k)=0$, where $\sigma $ denotes the shift forward operator and $A\left( \sigma \right) $ a regular polynomial matrix, the forward-backward behavior of this system can be constructed by using the finite and infinite elementary divisor structure of $A\left( \sigma \right) $. This work studies the inverse problem: Given a specific forward-backward behavior, find a family of regular or non-regular polynomial matrices $A\left( \sigma \right) $, such that the constructed system $A\left( \sigma \right) \beta \left( k\right) =0$ has exactly the ...


Website Review: Treehugger.Com, Brandi H. Johnson 2018 University of North Alabama

Website Review: Treehugger.Com, Brandi H. Johnson

Journal of Sustainability Studies

No abstract provided.


Book Review: Naomi Klein’S This Changes Everything: Capitalism Vs. The Climate, Jacob Dawson 2018 University of North Alabama

Book Review: Naomi Klein’S This Changes Everything: Capitalism Vs. The Climate, Jacob Dawson

Journal of Sustainability Studies

No abstract provided.


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