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Letter From The Editor - Hirst, Russel K. Hirst 2016 University of Tennessee - Knoxville

Letter From The Editor - Hirst, Russel K. Hirst

International Journal of Nuclear Security

No abstract provided.


Call For The Student Writing Competition, 2016 University of Tennessee, Knoxville

Call For The Student Writing Competition

International Journal of Nuclear Security

No abstract provided.


Table Of Contents, 2016 University of Tennessee, Knoxville

Table Of Contents

International Journal of Nuclear Security

No abstract provided.


Challenges And Responses For Ensuring Sustainability Of Insa Training Programs, Jongsook Kim, Hyung-kyung Lee, Jin-young Lee 2016 Korea Institute of Nuclear Nonproliferation and Contol

Challenges And Responses For Ensuring Sustainability Of Insa Training Programs, Jongsook Kim, Hyung-Kyung Lee, Jin-Young Lee

International Journal of Nuclear Security

Providing a systematic training is critical for a state or international perspective to reinforce nuclear security regime nationally or internationally. Korea government recognizes the importance of such challenge, and established the INSA under the KINAC as a Center of Excellence for fostering national nuclear security capacity and contributing international nuclear security governance. INSA started with the government policy that the establishment of sustainable education and training infrastructure and processes is fundamental to the capacity building strategy. After established, INSA has been designing and delivering the domestic and international/regional training programs for the purpose of fostering human resources development in ...


Promoting Excellence And Demonstrated Competence For Nuclear Security Training, Daniel Johnson, Brunelle Battistella, Roger Howsley 2016 World Institute for Nuclear Security

Promoting Excellence And Demonstrated Competence For Nuclear Security Training, Daniel Johnson, Brunelle Battistella, Roger Howsley

International Journal of Nuclear Security

The international community has spent considerable time, money, and effort attempting to establish a series of national and regional Centres of Excellence (COEs), also known as Nuclear Security Training and Support Centres (NSSCs). These Centres tend to have a wide variety of objectives, structures, and methods of delivery. Unsurprisingly, no internationally accepted standard exists on how they should operate. The IAEA has produced some excellent guidance (TECDOC 1734), but by virtue of its role cannot provide standards for benchmarking success. Against this backdrop, the World Institute for Nuclear Security (WINS) launched the WINS Academy, an initiative to provide practitioners with ...


Building The Education And Training Pillar Of The University Of Tennessee’S Institute For Nuclear Security, Howard Lewis Hall 2016 University of Tennessee, Knoxville

Building The Education And Training Pillar Of The University Of Tennessee’S Institute For Nuclear Security, Howard Lewis Hall

International Journal of Nuclear Security

The University of Tennessee (UT) developed its first formal and coordinated efforts in nuclear security education in 2008-2009 with its graduate certificate program in nuclear security in the Department of Nuclear Engineering. Building on this work, in 2011 UT established the UT Institute for Nuclear Security (INS) as a collaborative center at the university to expand its curricular impact as well as foster research and partnerships with nearby major governmental facilities engaged in nuclear security work. Oak Ridge National Laboratory (ORNL), the Y-12 National Security Complex (Y-12), and Oak Ridge Associated Universities (ORAU) have joined with UT as charter members ...


Nuclear Security Education At Pakistan Institute Of Engineering And Applied Sciences (Pieas): Current Status, Future Prospects And The Lessons Learnt, Tariq Majeed Dr. 2016 Pakistan Institute of Engineering and Applied Sciences

Nuclear Security Education At Pakistan Institute Of Engineering And Applied Sciences (Pieas): Current Status, Future Prospects And The Lessons Learnt, Tariq Majeed Dr.

International Journal of Nuclear Security

In this paper, the details of nuclear security education at Pakistan Institute of Engineering and Applied Sciences (PIEAS) have been discussed. Nuclear Security education was initiated at PIEAS as a sub-specialty of its MS Nuclear Engineering Program in October 2009. Two courses, Nuclear Security (NE-581) and Physical Protection Systems (NE-582) have been offered on regular basis in the 3rd and 4th semesters. To date, 72 students have been graduated with this sub-specialty. The most important lesson learnt is that introduction of nuclear security related courses in nuclear engineering program has opened up new venues of applications of nuclear ...


Nuclear Security And Hrd - Viet Nam’S Effort, Nu-Hoai-Vi Nguyen, Tan Huu Vuong 2016 Vietnam Agency for Radiation and Nuclear Safety (VARANS)

Nuclear Security And Hrd - Viet Nam’S Effort, Nu-Hoai-Vi Nguyen, Tan Huu Vuong

International Journal of Nuclear Security

Viet Nam is expanding its nuclear energy program for the application in various areas including industries, agriculture, healthcare, education and research. Recognizing the importance of the nineteen issues laid out in the IAEA document “Milestones in Development of a National Infrastructure for Nuclear Power” [1], Vietnam is considering how to address these issues. This paper describes the establishment of nuclear security infrastructure in Viet Nam and how Viet Nam has addressed one of the nineteen issues, that is human resource development in nuclear energy in general and in nuclear security in particular.


Feasibility Of The Use Of Neutron Activation Analysis Techniques In An Underwater Environment, Michael D. Chick 2016 Western Kentucky University

Feasibility Of The Use Of Neutron Activation Analysis Techniques In An Underwater Environment, Michael D. Chick

Masters Theses & Specialist Projects

Elements when bombarded with neutrons emit a gamma ray that is characteristic of the isotope that underwent a neutron induced nuclear reaction; this is known as neutron activation. The characteristic gamma energy of an isotope can then be detected and recorded. One can then analyze the gamma energies captured and determine the elemental makeup of the sample. This form of analysis can be used in an underwater environment making it potentially a valuable tool for agencies tasked with maritime security of ports and waterways, or clean-up operations. This thesis will focus on the feasibility of neutron interrogation using pulsed fast ...


Actinium-225 Production Via Proton Irradiation Of Thorium-232, Justin Reed Griswold 2016 University of Tennessee, Knoxville

Actinium-225 Production Via Proton Irradiation Of Thorium-232, Justin Reed Griswold

Doctoral Dissertations

High energy proton spallation reactions on natural thorium metal targets have been utilized to produce multi mCi [milliCurie] quantities of Actinium-225. Theoretical cross sections for actinium and thorium isotopes as well as for a select number of the fission products produced in these reactions were generated by the Monte Carlo radiation transport code PHITS to simulate the experimental data obtained from sixteen irradiations of thorium metal targets with 25-210 µA [microampere] proton beams ranging in energies from 77 to 192 MeV. Irradiations were conducted at Brookhaven National Laboratory (BNL) and Los Alamos National Laboratory (LANL), while target dissolution and processing ...


A Generalized Method For Fissile Material Characterization Using Short-Lived Fission Product Gamma Spectroscopy, Justin Richard Knowles 2016 University of Tennessee, Knoxville

A Generalized Method For Fissile Material Characterization Using Short-Lived Fission Product Gamma Spectroscopy, Justin Richard Knowles

Doctoral Dissertations

Characterizing the fissile content of nuclear materials is of particular interest to the safeguards and nuclear forensics communities. Short-lived fission product gamma spectroscopy offers a significant reduction in analysis time and detection limits when compared to traditional non-destructive assay measurements. Through this work, a fully generalizable method that can be applied to variations in fissile compositions and neutron spectra was developed for the modeling and measurement of short-lived fission product gamma-rays. This method uses a 238-group neutron flux that was characterized for two pneumatic tube positions in the High Flux Isotope Reactor using flux monitor irradiations. This flux spectrum was ...


Direct Dissolution And Electrochemical Investigation Of Cerium And Uranium In Ionic Liquid, Janelle Droessler 2016 University of Nevada, Las Vegas

Direct Dissolution And Electrochemical Investigation Of Cerium And Uranium In Ionic Liquid, Janelle Droessler

UNLV Theses, Dissertations, Professional Papers, and Capstones

The solubility, coordination and speciation of f-elements in ionic liquids (ILs) has been the focus of numerous studies because the purely ionic systems have unique physical properties that can be exploited in comparison to aqueous, organic, or molten salt systems. Ionic liquids are thermally stable, have negligible vapor pressure, and are electrochemically stable at negative potentials that encompass the reduction potential of actinide species. Literature has suggested that the properties of ILs could potentially be utilized in the nuclear fuel cycle for separations and reprocessing. However, the solubility of f-elements in ILs has been significantly lower compared to traditional solvents ...


Synthesis Of A Novel Cox-2 Inhibitor Analog For Pet Scan Imaging, Rebecca Neighbor 2016 University of Tennessee, Knoxville

Synthesis Of A Novel Cox-2 Inhibitor Analog For Pet Scan Imaging, Rebecca Neighbor

University of Tennessee Honors Thesis Projects

No abstract provided.


Cd Transport In Eutectic Licl-Kcl And Contamination Of Zr Metal And Thermal Dehydration Of Bulk Licl-Kcl, Nicholas Azoy Earle 2016 University of Tennessee - Knoxville

Cd Transport In Eutectic Licl-Kcl And Contamination Of Zr Metal And Thermal Dehydration Of Bulk Licl-Kcl, Nicholas Azoy Earle

Masters Theses

Researchers at Idaho National Labs have noted unexpectedly high Cd content in empty cladding hulls after processing in the Mark-IV ER. It has been theorized that Cd metal is transporting from the LCC pool through the eutectic LiCl-KCl salt bath to the anode baskets containing the empty hull where it is retained as a Zr-Cd intermetallic. This study sought to replicate the Cd contamination in a dry Ar glovebox using small-scale analogue of the Mark-IV ER salt-Cd metal system.

Anhydrous eutectic LiCl-KCl was an essential regent in this research and experiments were conducted to investigate the feasibility of dehydrating nominally ...


The Design And Synthesis Of Ghrelin Analogues As Non‐Invasive Ghs‐R1a Imaging Probes, Carlie L. Charlton 2016 The University of Western Ontario

The Design And Synthesis Of Ghrelin Analogues As Non‐Invasive Ghs‐R1a Imaging Probes, Carlie L. Charlton

Electronic Thesis and Dissertation Repository

The field of molecular imaging is constantly growing and evolving in order to provide the best possible healthcare for patients in various stages of disease and therapy. Molecular imaging aims to locate specific markers of disease by selectively targeting the markers of interest with high selectivity and visualizing the accumulation using external detection. The growth hormone secretagogue receptor-1a (GHS-R1a) has been shown to be involved in various important biological functions such as energy homeostasis and cardiac contractility. GHS-R1a has shown involvement in proliferation, migration and cell invasion of specific cancer subtypes. Therefore, targeting GHS-R1a is an important marker of different ...


Design Rules For The Nucleation, Growth, And Encapsulation Of Gold Nanoparticles With Applications To Cancer Imaging, Matthew A. Wall 2016 Graduate Center, City University of New York

Design Rules For The Nucleation, Growth, And Encapsulation Of Gold Nanoparticles With Applications To Cancer Imaging, Matthew A. Wall

All Dissertations, Theses, and Capstone Projects

Surface-enhanced Raman scattering (SERS) nanoparticles are exciting candidates for high-precision cancer imaging due to their highly specific spectral signature (Raman “fingerprint”) and propensity for passive targeting of cancerous tissues. However, the signal intensity of currently available SERS nanoparticles is insufficient for cancer imaging via passive targeting in most solid tumors. The overarching aim of this body of work is to develop a new generation of SERS nanoparticles with sufficiently low limits of detection to enable robust detection of various solid tumors in vivo.

The complexity of SERS nanoparticles requires significant advances to the theoretical and experimental understanding of metal nanoparticle ...


Investigation Of 89zr-Siderophores As Molecular Imaging Agents For Positron Emission Tomography Imaging Of Bacterial Infections, Nora C. M. Goscinski 2015 Washington University in St. Louis

Investigation Of 89zr-Siderophores As Molecular Imaging Agents For Positron Emission Tomography Imaging Of Bacterial Infections, Nora C. M. Goscinski

Arts & Sciences Electronic Theses and Dissertations

Siderophores are small molecules synthesized by bacteria to harvest Fe3+ from their environment. In infection scenarios, their production can increase infection virulence by increasing the ability of bacteria to obtain Fe3+ and therefore grow more rapidly. The selective uptake of siderophores in vivo in multi-bacteria environments indicates that this class of molecules has a potential use as selective imaging agents. In this work, DFO-NCS and a library of trihydroxamate siderophores were evaluated as vehicles to deliver 89Zr selectively to bacteria for Positron Emission Tomography (PET) imaging of bacterial infections.

Productive work with radiometals involves thorough knowledge of ...


Uses Of Diaryliodonium Salts And Methods For Their Synthesis, Jordan M. Veness 2015 University of Nebraska-Lincoln

Uses Of Diaryliodonium Salts And Methods For Their Synthesis, Jordan M. Veness

Student Research Projects, Dissertations, and Theses - Chemistry Department

Diaryliodonium salts have been studied continuously since the first report of their synthesis in 1894. Diaryliodonium salts are I(III) derivatives that are air- and moisturestable. The reactivity of these compounds resembles the organometallic chemistry of heavy transition metal ions such as Pb(IV), Hg(II), Th(III), and Pd(II). A significant advantage of diaryliodonium salts is that they can carry undergo many of the aryl functionalization reactions of heavy metal organometallic complexes, yet they have little to no toxicity and they are relatively inexpensive to prepare. The DiMagno laboratory uses diaryliodonium salts as precursors in the final synthetic ...


Exploring Rapid Radiochemical Separations At The University Of Tennessee Radiochemistry Center Of Excellence, Howard L. Hall, John D. Auxier II 2015 University of Tennessee - Knoxville

Exploring Rapid Radiochemical Separations At The University Of Tennessee Radiochemistry Center Of Excellence, Howard L. Hall, John D. Auxier Ii

Faculty Publications and Other Works -- Institute for Nuclear Security

The University of Tennessee formed its Radiochemistry Center of Excellence (RCoE) in 2013 with support from the U.S. National Nuclear Security Administration. One of the major thrusts of the RCoE is to develop deeper understanding of rapid methods for radiochemical separations that are relevant to both general radiochemical analyses as well as post-detonation nuclear forensics. Early work has included the development and demonstration of rapid separations of lanthanide elements in the gas phase, development of a gas-phase separation front-end for ICP-TOF-MS analysis, and the development of realistic analytical surrogates for post-detonation debris to support methods development.


The Development Of Cyclic Rgd Peptides Stabilized Through 99mtc/Re(Co)3+, Aagam Patel 2015 The University of Western Ontario

The Development Of Cyclic Rgd Peptides Stabilized Through 99mtc/Re(Co)3+, Aagam Patel

Electronic Thesis and Dissertation Repository

Protein secondary structure can be mimicked by incorporating structural constraints into peptides and this can be facilitated by metal coordination. The objective of this project is to establish a chelation system with a cancer targeting peptide sequence, where the coordination to a metal centre results in a cyclic metallopeptide. Cyclic RGD peptides are antagonists for αvβ3 and other integrins, which are present during tumour angiogenesis. Arg-Gly-Asp (RGD) sequence is employed in the peptide backbone, with an un-natural amino acid (3-Pal) and a chelating molecule (pyridyl-triazole, pyta) present on opposite ends of the peptide sequence to form a ...


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