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Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain 2017 Dominican University of California

Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain

Senior Theses and Capstone Projects

Our country’s healthcare system is at a moral crossroads. The way we treat those whom we call “the homeless” is deplorable. The majority of the homeless are mentally ill and need treatment. Our country needs to treat those with the severe brain diseases of schizophrenia, schizo-affective disorder, and bi-polar disorder just as we would Alzheimer’s disease and Parkinson’s disease. Those with severe mental illness, who have no insight into their illness, should not be allowed to dictate their own treatment. If a homeless person is brought to San Francisco General Hospital and is found to be a ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Tiffany A. Moore Simas

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Jeroan J. Allison

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Nancy Byatt

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis 2016 University of Massachusetts Boston

A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis

Douglas M. Ziedonis

Introduction: Korean American women prefer online or telephone smoking cessation interventions that can be remotely accessed from home. However, these interventions have been found ineffective for the group.

Methods: This study is a pilot clinical trial testing the feasibility and acceptability of a videoconferencing smoking cessation intervention for Korean American women and compared its preliminary efficacy with a telephone-based smoking cessation intervention. Korean women in the United States were recruited nationwide and randomly assigned at a ratio of 1:1 to either a video arm or a telephone arm. Participants in both arms received eight 30-minute weekly individualized counseling sessions ...


Duration Of Menopausal Vasomotor Symptoms Over The Menopause Transition, Nancy E. Avis, Sybil L. Crawford, Gail A. Greendale, Joyce T. Bromberger, Susan A. Everson-Rose, Ellen B. Gold, Rachel Hess, Hadine Joffe, Howard M. Kravitz, Ping G. Tepper, Rebecca C. Thurston 2016 Wake Forest University

Duration Of Menopausal Vasomotor Symptoms Over The Menopause Transition, Nancy E. Avis, Sybil L. Crawford, Gail A. Greendale, Joyce T. Bromberger, Susan A. Everson-Rose, Ellen B. Gold, Rachel Hess, Hadine Joffe, Howard M. Kravitz, Ping G. Tepper, Rebecca C. Thurston

Sybil L. Crawford

IMPORTANCE: The expected duration of menopausal vasomotor symptoms (VMS) is important to women making decisions about possible treatments.

OBJECTIVES: To determine total duration of frequent VMS ( > /= 6 days in the previous 2 weeks) (hereafter total VMS duration) during the menopausal transition, to quantify how long frequent VMS persist after the final menstrual period (FMP) (hereafter post-FMP persistence), and to identify risk factors for longer total VMS duration and longer post-FMP persistence.

DESIGN, SETTING, AND PARTICIPANTS: The Study of Women's Health Across the Nation (SWAN) is a multiracial/multiethnic observational study of the menopausal transition among 3302 women enrolled at ...


A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis 2016 University of Massachusetts Boston

A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis

Hua Julia Fang

Introduction: Korean American women prefer online or telephone smoking cessation interventions that can be remotely accessed from home. However, these interventions have been found ineffective for the group.

Methods: This study is a pilot clinical trial testing the feasibility and acceptability of a videoconferencing smoking cessation intervention for Korean American women and compared its preliminary efficacy with a telephone-based smoking cessation intervention. Korean women in the United States were recruited nationwide and randomly assigned at a ratio of 1:1 to either a video arm or a telephone arm. Participants in both arms received eight 30-minute weekly individualized counseling sessions ...


A Pilot Study To Assess The Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women At High Risk For Gestational Diabetes Mellitus, Ling Shi, Vidya Iyer, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Laura L. Hayman 2016 University of Massachusetts Boston

A Pilot Study To Assess The Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women At High Risk For Gestational Diabetes Mellitus, Ling Shi, Vidya Iyer, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Laura L. Hayman

Tiffany A. Moore Simas

Background: Diet plays an important role in the prevention and management of gestational diabetes mellitus (GDM). Previous studies suggest that soy protein and isoflavones may have beneficial effects on lipid and glucose metabolism. Little is known regarding the cardiometabolic effects of soy intake during pregnancy. This pilot study assessed the feasibility, safety and acceptability of daily consumption of soy foods during pregnancy in women at high risk for GDM, and participant adherence to their assigned treatment.

Methods: A randomized controlled trial (RCT) was conducted among pregnant women at high risk for GDM. The Soy group were counseled to consume a ...


Proposed Typologies For The Dress Needs Of Nursing Mothers And Babies And Available Nursing Dress: An Evaluation Of The Relationship Between Concepts In These Typologies, Ellen McKinney, Armine Ghalachyan 2016 Iowa State University

Proposed Typologies For The Dress Needs Of Nursing Mothers And Babies And Available Nursing Dress: An Evaluation Of The Relationship Between Concepts In These Typologies, Ellen Mckinney, Armine Ghalachyan

Ellen C. McKinney

In the U.S., the majority of babies are weaned from the breast by the time they are three months old (CDC, 2007) in contrast to the recommendation of “exclusive breastfeeding for about 6 months. . ., with continuation of breastfeeding for 1 year or longer” (Eidelman & Schanler, 2012). Women who feel comfortable feeding in public breastfeed longer than women who are not comfortable (Allen & Pelto, 1985). Practical advice on carrying out life roles while breastfeeding is important and requires consideration of clothing (Mulford 2008). The purposes of this study were to (1) identify and organize (a) dress needs of nursing mothers ...


Racial And Ethnic Disparities In Desire For Reversal Of Sterilization Among U.S. Women, Ginny Garcia-Alexander, Kelly Gonzales, Elizabeth Carol Hauck 2016 Portland State University

Racial And Ethnic Disparities In Desire For Reversal Of Sterilization Among U.S. Women, Ginny Garcia-Alexander, Kelly Gonzales, Elizabeth Carol Hauck

Ginny Garcia-Alexander

Purpose: Female sterilization rates and subsequent desire for reversal of the procedure are substantially higher in minorities, low-income women, and those who use public insurance. Despite the disproportionate distribution of these outcomes, few studies in this area have considered the extent to which such disparities are attributable to a restricted set of contraceptive options among medically underserved populations, which may in turn explain higher rates of desire for reversal. Methods: We use the most recent wave of NSFG data (2011-2013) to estimate odds ratios for race/ethnicity on the likelihood of desire for reversal of sterilization, while controlling for an ...


Racial And Ethnic Disparities In Desire For Reversal Of Sterilization Among U.S. Women, Ginny Garcia-Alexander, Kelly Gonzales, Elizabeth Carol Hauck 2016 Portland State University

Racial And Ethnic Disparities In Desire For Reversal Of Sterilization Among U.S. Women, Ginny Garcia-Alexander, Kelly Gonzales, Elizabeth Carol Hauck

Ginny Garcia-Alexander

Purpose: Female sterilization rates and subsequent desire for reversal of the procedure are substantially higher in minorities, low-income women, and those who use public insurance. Despite the disproportionate distribution of these outcomes, few studies in this area have considered the extent to which such disparities are attributable to a restricted set of contraceptive options among medically underserved populations, which may in turn explain higher rates of desire for reversal. Methods: We use the most recent wave of NSFG data (2011-2013) to estimate odds ratios for race/ethnicity on the likelihood of desire for reversal of sterilization, while controlling for an ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

UMass Center for Clinical and Translational Science Supported Publications

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Intersecting Positions Of Social Disadvantage And Self-Reported Health Status Disparities, Carla S. Alvarado, Chunhuei Chi 2016 Oregon State University

Intersecting Positions Of Social Disadvantage And Self-Reported Health Status Disparities, Carla S. Alvarado, Chunhuei Chi

Journal of Health Disparities Research and Practice

Health disparities along the gender, race and class are particularly important to monitor and study given the predicted differential distribution of health along these social identities. Intersectionality is a theoretical framework that allows public health and health disparities researchers to account for the simultaneous, mutually constitutive, reinforcing and multidimensional effects of gender, class, and race with the aim to better understand health disparities. Disparities along gender, race and class have been noted in self-reported health status (SRHS) which has been shown to be a strong predictive factor of mortality, morbidity and mental health independent of other physiologic, behavioral and psychosocial ...


Older Women’S Muscle And Gait Response To A Bout Of Exercise Differs By Physical Activity Level, Jocelyn F. Hafer, Katherine A. Boyer 2016 University of Massachusetts Amherst

Older Women’S Muscle And Gait Response To A Bout Of Exercise Differs By Physical Activity Level, Jocelyn F. Hafer, Katherine A. Boyer

UMass Center for Clinical and Translational Science Research Retreat

Changes in gait are a consequence of aging and likely contribute to knee osteoarthritis (OA) incidence. Decrements in muscle function with age, including muscle power and fatigue resistance, may contribute to changes in gait and, subsequently, knee OA. Examining the impact of habitual physical activity (PA) on gait mechanics and muscle function may provide insight for interventions to modify knee OA risk. As knee OA affects women at greater rates than men, the current study focused on older women. The aim of this study was to determine if older women with different levels of habitual PA experienced the same effect ...


A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis 2016 University of Massachusetts Boston

A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis

UMass Center for Clinical and Translational Science Research Retreat

Introduction: Korean American women prefer online or telephone smoking cessation interventions that can be remotely accessed from home. However, these interventions have been found ineffective for the group.

Methods: This study is a pilot clinical trial testing the feasibility and acceptability of a videoconferencing smoking cessation intervention for Korean American women and compared its preliminary efficacy with a telephone-based smoking cessation intervention. Korean women in the United States were recruited nationwide and randomly assigned at a ratio of 1:1 to either a video arm or a telephone arm. Participants in both arms received eight 30-minute weekly individualized counseling sessions ...


Discovery And Development Of Human Monoclonal Antibodies To Block Rhd Alloimmunization During Pregnancy, Tushar Gupta, Melissa Gawron, Colby A. Souders, Michael A. Brehm, Dale Greiner, Leonard D. Shultz, Smita Jaiswal, Sean McCauley, Ann Dauphin, Jeremy Luban, Lisa Cavacini 2016 University of Massachusetts Medical School

Discovery And Development Of Human Monoclonal Antibodies To Block Rhd Alloimmunization During Pregnancy, Tushar Gupta, Melissa Gawron, Colby A. Souders, Michael A. Brehm, Dale Greiner, Leonard D. Shultz, Smita Jaiswal, Sean Mccauley, Ann Dauphin, Jeremy Luban, Lisa Cavacini

UMass Center for Clinical and Translational Science Research Retreat

Exposure of an Rh negative mother to red blood cells (RBCs) of an Rh positive fetus results in alloimmunization and development of anti-RhD antibodies. The anti-RhD antibodies cause hemolytic disease of the new born babies during subsequent pregnancies. Current prophylactic treatment involves polyclonal anti-RhD IgG purified from plasma of humans and is administered in approximately 20% of pregnancies. While the current prophylaxis is effective, it involves the use of human plasma and non-RhD specific antibodies, thus posing a risk of transmitting infections and undesired antibody reactions. Moreover, there is a serious scarcity of plasma donors to meet the requirement of ...


Does The Indication For Breast Surgery Impact Surgical Outcomes? A Contemporary Analysis Of The Acs-Nsqip Database, Connie Lee, Ann-Kristin U. Friedrich, Anne C. Larkin, B. Marie Ward, Ashling O'Connor, Robert M. Quinlan, Giles F. Whalen, Jennifer LaFemina 2016 University of Massachusetts Medical School

Does The Indication For Breast Surgery Impact Surgical Outcomes? A Contemporary Analysis Of The Acs-Nsqip Database, Connie Lee, Ann-Kristin U. Friedrich, Anne C. Larkin, B. Marie Ward, Ashling O'Connor, Robert M. Quinlan, Giles F. Whalen, Jennifer Lafemina

UMass Center for Clinical and Translational Science Research Retreat

Background. There is limited data about whether perioperative outcomes differ based on the indication for breast surgery. Herein we aim to assess if breast surgery for prophylaxis, compared to that for malignancy, impacts surgical outcomes.

Methods. All women who underwent simple or subcutaneous mastectomy were identified from the 2007-2012 ACS-NSQIP database. Patients were identified by their ICD-9 codes and categorized into two groups. Group 1 consisted of patients diagnosed with breast cancer or carcinoma in situ; group 2 consisted of patients diagnosed with a genetic predisposition to malignant neoplasm of the breast (i.e., BRCA mutation). Demographic and preoperative variables ...


A Pilot Study To Assess The Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women At High Risk For Gestational Diabetes Mellitus, Ling Shi, Vidya Iyer, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Laura L. Hayman 2016 University of Massachusetts Boston

A Pilot Study To Assess The Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women At High Risk For Gestational Diabetes Mellitus, Ling Shi, Vidya Iyer, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Laura L. Hayman

UMass Center for Clinical and Translational Science Research Retreat

Background: Diet plays an important role in the prevention and management of gestational diabetes mellitus (GDM). Previous studies suggest that soy protein and isoflavones may have beneficial effects on lipid and glucose metabolism. Little is known regarding the cardiometabolic effects of soy intake during pregnancy. This pilot study assessed the feasibility, safety and acceptability of daily consumption of soy foods during pregnancy in women at high risk for GDM, and participant adherence to their assigned treatment.

Methods: A randomized controlled trial (RCT) was conducted among pregnant women at high risk for GDM. The Soy group were counseled to consume a ...


Contemporary Analysis Of Malignancies In Women Of Child-Bearing Age: An Nsqip Analysis, Eva Rouanet, Ann-Kristin U. Friedrich, Kate Dinh, Kevin P. Baratta, Giles F. Whalen, Heena Santry, Jennifer LaFemina 2016 University of Massachusetts Medical School

Contemporary Analysis Of Malignancies In Women Of Child-Bearing Age: An Nsqip Analysis, Eva Rouanet, Ann-Kristin U. Friedrich, Kate Dinh, Kevin P. Baratta, Giles F. Whalen, Heena Santry, Jennifer Lafemina

UMass Center for Clinical and Translational Science Research Retreat

Background: Recent evidence suggests that cancer incidence among pregnant women is increasing. The pattern of malignancies in pregnant women and how these compare to their nonpregnant counterparts has not been explored. Here we describe the differences in the proportion of resected malignancies in this population. Methods: The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was used to identify women aged 18-49 who underwent an operation for malignancy from 2007-2012. Age-adjusted distribution of specific surgical interventions for malignancy based on ICD-9 codes were compared among pregnant and non-pregnant women using logistic regression analysis. Results: 42,732 subjects ...


Association Between First Trimester Pregnancy Associated Plasma Protein–A And The Development Of Gestational Diabetes Mellitus, Aylin Sert, Katherine Leung, Molly E. Waring, Raziel Rojas-Rodriguez, Silvia Corvera, Tiffany A. Moore Simas 2016 University of Massachusetts Medical School

Association Between First Trimester Pregnancy Associated Plasma Protein–A And The Development Of Gestational Diabetes Mellitus, Aylin Sert, Katherine Leung, Molly E. Waring, Raziel Rojas-Rodriguez, Silvia Corvera, Tiffany A. Moore Simas

UMass Center for Clinical and Translational Science Research Retreat

Background: Gestational diabetes (GDM) is a common pregnancy complication with significant cardiometabolic consequences for mothers and offspring. Previous research from our group suggests that adipose tissue IGFBP-5 and its unique metalloprotease PAPP-A (Pregnancy Associated Plasma Protein-A) may play mechanistic roles in GDM development by regulating functional IGF-1 levels and lipid storage and metabolism.

Aim: To examine the relationship between circulating PAPP-A levels and GDM development. We hypothesized that high first trimester PAPP-A levels would be associated with decreased GDM risk.

Methods: A retrospective cohort of women delivering singleton gestations at UMass Memorial Healthcare (2009, 2010, 2014, 2015) was assembled by ...


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