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Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women: Preliminary Results From A Pilot Randomized Controlled Trial, Ling Shi, Vidya Iyer, Errol Norwitz, Tiffany A. Moore Simas, Nirupa R. Matthan, Alice H. Lichtenstein, Laura L. Hayman 2017 University of Massachusetts Boston

Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women: Preliminary Results From A Pilot Randomized Controlled Trial, Ling Shi, Vidya Iyer, Errol Norwitz, Tiffany A. Moore Simas, Nirupa R. Matthan, Alice H. Lichtenstein, Laura L. Hayman

Tiffany A. Moore Simas

Background: Previous evidence suggests that soy containing foods may have beneficial effects on lipid and glycemic metabolism. Pregnancy is associated with a progressive deterioration in glucose and lipid metabolism, partially attributable to elevated estrogen concentrations. Little is known about the effects of soy intake on cardiometabolic risk factors in pregnant women. Methods: A pilot RCT was conducted in 30 pregnant women who were randomized to receive counseling to consume a high-soy or low-soy foods containing diet. Assessments (physical measurements, food frequency questionnaires, fasting blood samples) were conducted at 14 and 28 weeks of pregnancy, and 6 weeks’ postpartum. Monthly follow-up ...


Addressing The Racial Disparity In Birth Outcomes: Implications For Maternal Racial Identity On Birthweight, Wanda M. Burton, Maria Hernandez-Reif, Brad Lian 2017 University of Alabama - Tuscaloosa

Addressing The Racial Disparity In Birth Outcomes: Implications For Maternal Racial Identity On Birthweight, Wanda M. Burton, Maria Hernandez-Reif, Brad Lian

Journal of Health Disparities Research and Practice

Background: As a widely used marker of health, birthweight has been a persistent racialized disparity with the low birthweight rate of Blacks in Alabama nearly doubling the national average. The purpose of this study was to examine the role of racial identity and acculturation on birthweight in a sample of Black women living in Alabama.

Methods: Black women (n=72) in West Alabama were surveyed about the birthweight of their first born child. Correlation and multiple linear regression analyses were conducted.

Results: Racial identity was the only significant predictor of birthweight. Mothers with a strong racial identity reported having low ...


Residential Segregation, Neighborhood Social And Physical Context In Obesity Disparities In Hispanic Preschoolers: A Conceptual Model, Catherina Chang Martinez PhD(c), Nasar U. Ahmed PhD, Ruby A. Natale PhD, PsyD 2017 Robert Stempel College of Public Health and Social Work, Florida International University

Residential Segregation, Neighborhood Social And Physical Context In Obesity Disparities In Hispanic Preschoolers: A Conceptual Model, Catherina Chang Martinez Phd(C), Nasar U. Ahmed Phd, Ruby A. Natale Phd, Psyd

Journal of Health Disparities Research and Practice

During the last decade, there has been a significant inclusion in obesity prevention studies from individual characteristics to household factors then neighborhood factors. The study of place in the context of early childhood obesity studies has been limited to the food and physical built environment. With the persistent disparities in the prevalence of childhood obesity, and Hispanic minorities being increasingly affected, there is a need to reexamine existing models and develop new model conceptual frameworks to examine the role of place and residential segregation in the context of race, ethnicity, social position, and socioeconomic disparities. In the context of place ...


Community-Level Characteristics Of High Infant Mortality: A Tool To Identify At-Risk Communities, Brandi M. White, Lee S. Horton, Kit N. Simpson 2017 Medical University of South Carolina

Community-Level Characteristics Of High Infant Mortality: A Tool To Identify At-Risk Communities, Brandi M. White, Lee S. Horton, Kit N. Simpson

Journal of Health Disparities Research and Practice

Infant mortality (IM) rate is a key indicator of population health and has been gradually improving in the United States. However, it is still a public health problem among minority and low-income communities. Maternal factors explain some of the variation, but community-level factors may also be a contributor. This study examines measures to identify a set of indicators that explain variations in IM at the community-level. Data for 77 communities in a city were obtained from local health databases. We used multivariable linear regression models to examine the strength of the association between IM and maternal, population, community wealth, and ...


Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey 2017 University of Massachusetts Medical School

Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey

Heather Z Sankey MD

This study examined racial/ethnic differences in gestational weight gain (GWG) predictors and association of first-trimester GWG to overall GWG among 271 White women and 300 Latina women. Rates of within-guideline GWG were higher among Latinas than among Whites (28.7% versus 24.4%, p < 0.016). Adjusted odds of above-guideline GWG were higher among prepregnancy overweight (OR = 3.4, CI = 1.8-6.5) and obese (OR = 4.5, CI = 2.3-9.0) women than among healthy weight women and among women with above-guideline first-trimester GWG than among those with within-guideline first-trimester GWG (OR = 4.9, CI = 2.8-8.8 ...


Supporting Mothers With Mental Illness: Postpartum Mental Health Service Linkage As A Matter Of Public Health And Child Welfare Policy, Jesse Krohn, MSEd, JD, Meredith Matone, DrPH, MHS 2017 Drexel University

Supporting Mothers With Mental Illness: Postpartum Mental Health Service Linkage As A Matter Of Public Health And Child Welfare Policy, Jesse Krohn, Msed, Jd, Meredith Matone, Drph, Mhs

Journal of Law and Health

Through our work in youth advocacy as, respectively, legal and public health professionals, we are all too aware of the high levels of health care fragmentation experienced during pregnancy and postpartum by poor, young mothers of color. Meredith Matone’s research highlights the heightened risk of fragmentation for girls with histories of child welfare involvement. For example, she found that 66.7% of young mothers who had resided in out-of-home placements and who had taken antipsychotic medication prior to becoming pregnant failed to fill prescriptions for antipsychotics in their first postpartum year. Put another way, two-thirds of these vulnerable young ...


Abnormal Dendritic Maturation Of Developing Cortical Neurons Exposed To Corticotropin Releasing Hormone (Crh): Insights Into Effects Of Prenatal Adversity?, Megan M. Curran, Curt A. Sandman, Elyssia Poggi Davis, Laura M. Glynn, Tallie Z. Baram 2017 University of California, Irvine

Abnormal Dendritic Maturation Of Developing Cortical Neurons Exposed To Corticotropin Releasing Hormone (Crh): Insights Into Effects Of Prenatal Adversity?, Megan M. Curran, Curt A. Sandman, Elyssia Poggi Davis, Laura M. Glynn, Tallie Z. Baram

Psychology Faculty Articles and Research

Corticotropin releasing hormone (CRH) produced by the hypothalamus initiates the hypothalamic- pituitary-adrenal (HPA) axis, which regulates the body's stress response. CRH levels typically are undetectable in human plasma, but during pregnancy the primate placenta synthesizes and releases large amounts of CRH into both maternal and fetal circulations. Notably, placental CRH synthesis increases in response to maternal stress signals. There is evidence that human fetal exposure to high concentrations of placental CRH is associated with behavioral consequences during infancy and into childhood, however the direct effects on of the peptide on the human brain are unknown. In this study, we ...


Collaboration To Promote Healthy Teen Development., Kimberly A. Greder 2017 Iowa State University

Collaboration To Promote Healthy Teen Development., Kimberly A. Greder

Kimberly A. Greder

The teen years are a transitional period for both teens and parents, particularly when there are special challenges and needs. Adults have great opportunities during this period to help teens transition positively into adulthood. While the key principles of healthy teen development have not changed over the years, the context in which teens develop has changed. The period of adolescence begins earlier today than in prior years, teens have more sporadic and less intense contact with parents than they did in the past, peers provide a strong sense of social support, schools are larger and less personal, and technology has ...


Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey 2017 University of Massachusetts Medical School

Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey

Tiffany A. Moore Simas

This study examined racial/ethnic differences in gestational weight gain (GWG) predictors and association of first-trimester GWG to overall GWG among 271 White women and 300 Latina women. Rates of within-guideline GWG were higher among Latinas than among Whites (28.7% versus 24.4%, p < 0.016). Adjusted odds of above-guideline GWG were higher among prepregnancy overweight (OR = 3.4, CI = 1.8-6.5) and obese (OR = 4.5, CI = 2.3-9.0) women than among healthy weight women and among women with above-guideline first-trimester GWG than among those with within-guideline first-trimester GWG (OR = 4.9, CI = 2.8-8.8). GWG was positively associated with neonate birth size (p < 0.001). Interventions targeting prepregnancy overweight or obese women and those with excessive first-trimester GWG are needed.


Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey 2017 University of Massachusetts Medical School

Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey

Milagros C. Rosal

This study examined racial/ethnic differences in gestational weight gain (GWG) predictors and association of first-trimester GWG to overall GWG among 271 White women and 300 Latina women. Rates of within-guideline GWG were higher among Latinas than among Whites (28.7% versus 24.4%, p < 0.016). Adjusted odds of above-guideline GWG were higher among prepregnancy overweight (OR = 3.4, CI = 1.8-6.5) and obese (OR = 4.5, CI = 2.3-9.0) women than among healthy weight women and among women with above-guideline first-trimester GWG than among those with within-guideline first-trimester GWG (OR = 4.9, CI = 2.8-8.8). GWG was positively associated with neonate birth size (p < 0.001). Interventions targeting prepregnancy overweight or obese women and those with excessive first-trimester GWG are needed.


Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey 2017 University of Massachusetts Medical School

Predictors Of Gestational Weight Gain Among White And Latina Women And Associations With Birth Weight, Milagros C. Rosal, Monica L. Wang, Tiffany A. Moore Simas, Jamie S. Bodenlos, Sybil L. Crawford, Katherine Leung, Heather Z. Sankey

Sybil L. Crawford

This study examined racial/ethnic differences in gestational weight gain (GWG) predictors and association of first-trimester GWG to overall GWG among 271 White women and 300 Latina women. Rates of within-guideline GWG were higher among Latinas than among Whites (28.7% versus 24.4%, p < 0.016). Adjusted odds of above-guideline GWG were higher among prepregnancy overweight (OR = 3.4, CI = 1.8-6.5) and obese (OR = 4.5, CI = 2.3-9.0) women than among healthy weight women and among women with above-guideline first-trimester GWG than among those with within-guideline first-trimester GWG (OR = 4.9, CI = 2.8-8.8 ...


Aplastic Anemia: Clinicohaematological Features, Treatment And Outcome Analysis, Rabia Wali, Zehra Fidoo, Salman Adil, Muhammad Ahmed Naqvi 2017 Aga Khan University

Aplastic Anemia: Clinicohaematological Features, Treatment And Outcome Analysis, Rabia Wali, Zehra Fidoo, Salman Adil, Muhammad Ahmed Naqvi

Salman Naseem Adil

Objective: To determine the clinicohaematological features, treatment and outcome of children diagnosed with aplastic anemia at a single institution. Study Design: Observational study. Place and Duration of Study: The Aga Khan University Hospital, Karachi, from January 1999 till December 2008. Methodology: Medical records of children aged less than 15 years of age diagnosed with aplastic anemia were reviewed. Clinicohaematological features, treatment and its response to therapy and outcome were recorded. Results were described in percentages. Results: Ninety patients were diagnosed to have aplastic anemia (AA); 65 were male during the study period. Age ranged from 1 to 15 years. Fever ...


Prenatal Care Enhanced With Digital Health Tools Can Reduce Visit Frequency While Improving Patient Satisfaction, Kathryn I. Marko, Nihar Ganju, Anish Sebastian, Joshua Benham 2017 George Washington University

Prenatal Care Enhanced With Digital Health Tools Can Reduce Visit Frequency While Improving Patient Satisfaction, Kathryn I. Marko, Nihar Ganju, Anish Sebastian, Joshua Benham

Medicine Faculty Posters and Presentations

100 low-risk obstetric patients were enrolled to evaluate the use of digital health technology in prenatal care. 50 patients were placed on an alternate prenatal care schedule (8 visits), supplemented with an integrated technology platform of a mobile application and connected devices including a wireless weight scale and blood pressure cuff. The remaining 50 control patients received routine care, without the technology platform. Patients were evaluated for satisfaction and engagement throughout pregnancy.


Paying It Forward: Training Doulas As A Form Of Reintegration And Support For Communities Of Color, Sandra E. Luna-Martinez 2017 The University of San Francisco

Paying It Forward: Training Doulas As A Form Of Reintegration And Support For Communities Of Color, Sandra E. Luna-Martinez

Master's Projects and Capstones

As part of the birth justice movement in Alameda County, Roots of Labor Birth Collective (RLBC) is committed to support, empower and care for birthing members of the community. RLBC works to empower people of color with education and tools to have healthy babies and positive birth experiences regardless of their: gender, size, sexuality, orientation, culture or family structure. Healthy families begin with healthy communities and with that in mind, RLBC decided to tackle two major public health issues at once: recidivism and poor birth outcomes in communities of color. Doula training is not just an intervention to improve birth ...


Fetal And Childhood Effects Of Children Exposed To Opioids, Opioid Maintenance Therapy (Omt), And Methamphetamine In Utero, Seth Peters 2017 Rhode Island Department of Health

Fetal And Childhood Effects Of Children Exposed To Opioids, Opioid Maintenance Therapy (Omt), And Methamphetamine In Utero, Seth Peters

UMass Center for Clinical and Translational Science Research Retreat

The opioid use epidemic in the U.S. is a well-known growing problem. According to the U.S. Department of Health & Human Services, opioid use has increased nationally nearly 400% over the past 18 years1. Subsequently, Opioid Maintenance Therapy (OMT), methadone or buprenorphine, is expanding2. Additionally, methamphetamine (MA) use and abuse is a continuing problem worldwide. Rates of MA use are high In the U.S. and overseas rates are greater3. Opioid and MA use affects not only the user, but also friends, family, and the communities close to them4,5. A child exposed to opioids ...


Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women: Preliminary Results From A Pilot Randomized Controlled Trial, Ling Shi, Vidya Iyer, Errol Norwitz, Tiffany A. Moore Simas, Nirupa R. Matthan, Alice H. Lichtenstein, Laura L. Hayman 2017 University of Massachusetts Boston

Feasibility, Safety And Acceptability Of Soy-Based Diet For Pregnant Women: Preliminary Results From A Pilot Randomized Controlled Trial, Ling Shi, Vidya Iyer, Errol Norwitz, Tiffany A. Moore Simas, Nirupa R. Matthan, Alice H. Lichtenstein, Laura L. Hayman

UMass Center for Clinical and Translational Science Research Retreat

Background: Previous evidence suggests that soy containing foods may have beneficial effects on lipid and glycemic metabolism. Pregnancy is associated with a progressive deterioration in glucose and lipid metabolism, partially attributable to elevated estrogen concentrations. Little is known about the effects of soy intake on cardiometabolic risk factors in pregnant women.

Methods: A pilot RCT was conducted in 30 pregnant women who were randomized to receive counseling to consume a high-soy or low-soy foods containing diet. Assessments (physical measurements, food frequency questionnaires, fasting blood samples) were conducted at 14 and 28 weeks of pregnancy, and 6 weeks’ postpartum. Monthly follow-up ...


Working With Pregnant & Postpartum Women With Opioid Use Dependence: Digital Storytelling As An Innovative Qualitative Data Collection Tool And Intervention, Alice Fiddian-Green 2017 University of Massachusetts Amherst

Working With Pregnant & Postpartum Women With Opioid Use Dependence: Digital Storytelling As An Innovative Qualitative Data Collection Tool And Intervention, Alice Fiddian-Green

UMass Center for Clinical and Translational Science Research Retreat

As part of the mini-symposium entitled "Pregnant and Parenting Mothers with History of Opiate Addiction," this presentation describes a qualitative study that will use digital storytelling with pregnant women in a medication assisted treatment (MAT) program as an intervention to promote self-efficacy as well as a patient-centered data collection tool.


Substance Use Disorder In Pregnancy: Improving Care And Reducing Risk In Franklin County With Empower, Linda Jablonski 2017 The Birthplace at Baystate Franklin Medical Center

Substance Use Disorder In Pregnancy: Improving Care And Reducing Risk In Franklin County With Empower, Linda Jablonski

UMass Center for Clinical and Translational Science Research Retreat

As part of the mini-symposium entitled "Pregnant and Parenting Mothers with History of Opiate Addiction," this presentation describes Project EMPOWER, an innovative hospital-based intervention to improve management of neonatal abstinence syndrome through the use of rooming-in and access to a designated psychotherapist.


Caring For Substance Exposed Newborns, Rachana Singh 2017 University of Massachusetts Medical School, Baystate Health

Caring For Substance Exposed Newborns, Rachana Singh

UMass Center for Clinical and Translational Science Research Retreat

As part of the mini-symposium entitled "Pregnant and Parenting Mothers with History of Opiate Addiction," this presentation describes innovations in care for substance exposed newborns while highlighting the gaps in services antepartum and post hospital discharge.


Obstacles For The Implementation Of Fertility And Family Planning Initiatives In Post Conflict Rwanda, Elizabeth Cave, Dakota Wayne 2017 University of Wyoming

Obstacles For The Implementation Of Fertility And Family Planning Initiatives In Post Conflict Rwanda, Elizabeth Cave, Dakota Wayne

Honors Theses AY 16/17

Increased measures by the State government to educate people on Family Planning and to provide access to contraceptives has had promising results in many countries in reducing poverty and raising the standard of living. However, it remains unclear whether these measures can have similar results in a post-conflict setting. Rwanda is the ideal setting to study these questions. The horrible genocide that occurred in Rwanda had a dramatic effect on the population in terms of infrastructure, fertility rates, and trust in the government. As the country is the most populous in the African continent as well as the site of ...


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