Aga Khan University
Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Louisville
La Salle University
SIT Study Abroad
Independent Researcher
Portland State University
Lstm-Based Recurrent Neural Network Predicts Influenza-Like-Illness In Variable Climate Zones,
2024
Noorda College of Osteopathic Medicine
Lstm-Based Recurrent Neural Network Predicts Influenza-Like-Illness In Variable Climate Zones, Alfred Amendolara, Christopher Gowans, Joshua Barton, David Sant, Andrew Payne
Annual Research Symposium
Purpose: Influenza virus is responsible for a recurrent, yearly epidemic in most temperate regions of the world. For the 2021-2022 season the CDC reports 5000 deaths and 100,000 hospitalizations, a significant number despite the confounding presence of SARS-CoV-2. The mechanisms behind seasonal variance in flu burden are not well understood. Based on a previously validated model, this study seeks to expand understanding of the impact of variable climate regions on seasonal flu trends. To that end, three climate regions have been selected. Each region represents a different ecological region and provides different weather patterns showing how the climate variables impact …
Influenza Prevalence And Risk Factors: A Population-Based Cross-Sectional Study,
2023
Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia
Influenza Prevalence And Risk Factors: A Population-Based Cross-Sectional Study, Kiran Ganesh Balakrishnan, Mohd Rizal Abd Manaf, Mohd Rohaizat Hassan, Mohd Kamarul Imran Musa, Azizul Rahman Mohamad Jamil, Norhaslira Abdul Rahim, Umi Kalsom Satariah Ali, Rahman Jamal
Makara Journal of Health Research
Background: Influenza infection can lead to mortality and morbidity. In densely populated Kuala Lumpur, Malaysia, the transmission of influenza-like illness (ILI) is high. This study assessed the prevalence and epidemiology of influenza in the target population.
Methods: A cross-sectional convenience sample study was conducted in government clinics of Cheras, Malaysia, from November 1, 2022, to February 28, 2023. Consent was sought from patients older than 18 years with symptoms of ILI (fever, cough, and onset within 10 days). A nasopharyngeal swab preceded an influenza rapid test. Logistic regression was used in SPSS 22.0 to evaluate the data.
Results …
The Effects Of An Influenza Vaccine Education Bundle On Environmental Management Services Workers,
2023
University of St. Augustine for Health Sciences
The Effects Of An Influenza Vaccine Education Bundle On Environmental Management Services Workers, Michelle Keister
Student Scholarly Projects
Practice Problem: Environmental Management Service Workers have low vaccination rates. They work around a vulnerable patient population.
PICOT: For Environmental Management Services (EMS) workers (P), does the use of an Influenza Vaccine Education Bundle (I) compared to the current practice (C) impact EMS worker influenza vaccine compliance (O) within a 10-week period (T)?
Evidence: Using an educational vaccine bundle that increases access to the vaccine, provides education regarding the vaccine, and comes from a trusted source will increase flu vaccination rates among Environmental Management Services workers.
Intervention: Implement a vaccine education bundle.
Outcome: After implementation in 2023, vaccination rates …
Improving Overall Capability Of Chinese Medical Science And Technology For Targeting People’S Health,
2023
National Academy of Innovation Strategy, Beijing 100038, China
Improving Overall Capability Of Chinese Medical Science And Technology For Targeting People’S Health, Shanchao Wu, Wei Wu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Medicine and life health field is the most active and potential strategic sector in the science and technology innovation system, and is also an important guarantee to improve people’s health, promote the progress of social civilization, and maintain national security. China’s medical research system is weak in basic research, with few breakthroughs in cutting-edge innovation and high dependence on foreign medical equipment and instruments, so it is urgent to strengthen the weaknesses and make up for the shortcomings. Under the strategic guidance of “Four-pronged”, China should strengthen strategic thinking and system concepts, comprehensively plan the medium- and long-term medical science …
Igg3 Subclass Antibodies Recognize Antigenically Drifted Influenza Viruses And Sars-Cov-2 Variants Through Efficient Bivalent Binding,
2023
Thomas Jefferson University
Igg3 Subclass Antibodies Recognize Antigenically Drifted Influenza Viruses And Sars-Cov-2 Variants Through Efficient Bivalent Binding, Marcus J. Bolton, Jefferson J.S. Santos, Claudia P. Arevalo, Trevor Griesman, Megan Watson, Shuk Hang Li, Paul Bates, Holly Ramage, Patrick C. Wilson, Scott E. Hensley
Department of Microbiology and Immunology Faculty Papers
The constant domains of antibodies are important for effector functions, but less is known about how they can affect binding and neutralization of viruses. Here, we evaluated a panel of human influenza virus monoclonal antibodies (mAbs) expressed as IgG1, IgG2, or IgG3. We found that many influenza virus-specific mAbs have altered binding and neutralization capacity depending on the IgG subclass encoded and that these differences result from unique bivalency capacities of the subclasses. Importantly, subclass differences in antibody binding and neutralization were greatest when the affinity for the target antigen was reduced through antigenic mismatch. We found that antibodies expressed …
Neurotropic Manifestations As A Potential Risk Factor For Schizophrenia Following In Utero Exposure To Sars-Cov-2,
2023
University of Louisville
Neurotropic Manifestations As A Potential Risk Factor For Schizophrenia Following In Utero Exposure To Sars-Cov-2, Mir Ali R Talpur, Omar H. Elsayed, Rif S. El-Mallakh
The University of Louisville Journal of Respiratory Infections
Background: COVID-19 infection is associated with neurologic and psychiatric morbidity that suggests a direct effect of the virus or secondary effect of an inflammatory process. These neuropsychiatric consequences may increase the likelihood of schizophrenia in the offspring of women who become infected with COVID-19 during their pregnancy.
Methods: We performed a directed narrative review of the literature focusing on the proposed pathophysiological processes that lead to schizophrenia and known pathological consequences of COVID-19 infection.
Results: Schizophrenia in adult offspring has been associated with maternal infections during pregnancy by a wide range of respiratory and neurotropic pathogens. Spikes in the incidence …
The Impact Of The Covid-19 Pandemic On Respiratory Syncytial Virus,
2023
University of Louisville
The Impact Of The Covid-19 Pandemic On Respiratory Syncytial Virus, Amrit Kahlon, Ravina Ramnani, Kartik Rajpal, Yusra Irshad, Sudeep Chapagain, Arushee Bhatnagar, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
On The Respiratory Syncytial Virus Vaccine,
2023
University of Louisville
On The Respiratory Syncytial Virus Vaccine, Forest W. Arnold
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Identification Of Molecular Markers Associated With Copd In Non-Smokers And Smokers: A Bioinformatics Analysis,
2023
University of Ilorin, Ilorin
Identification Of Molecular Markers Associated With Copd In Non-Smokers And Smokers: A Bioinformatics Analysis, Agede O. Ayodele, Isa M. Wasagu, Ademola E. Fawibe, Alakija K. Salami
The University of Louisville Journal of Respiratory Infections
Background
Even though the proportional burden of COPD among never-smokers is significant in both developing and developed nations, accounting for around 30% of all COPD in the community, there is little awareness of the prevalence of COPD in this population. Understanding the molecular processes that underlie COPD in nonsmokers is essential.
Methods
Dataset (GSE146560) was acquired from the Gene Expression Omnibus (GEO). The limma and clusterProfiler software tools were used to identify differentially expressed genes (DEGs) and conduct a functional enrichment analysis respectively.
Results
In all, 10,583 DEGs were found, of which 1,065 were up-regulated and 9,518 were down-regulated. The …
Performance Of A Sars-Cov-2 Rt-Pcr Assay With Non-Traditional Specimen Types,
2023
University of Louisville
Performance Of A Sars-Cov-2 Rt-Pcr Assay With Non-Traditional Specimen Types, Subathra Marimuthu, Holly Aliesky, Heather Ness, Daniya Sheikh, Sathya Rashmit, Dawn Balcom, Leslie A. Wolf
The University of Louisville Journal of Respiratory Infections
During the first two years of the coronavirus disease 2019 (COVID-19) pandemic, nasopharyngeal (NP) specimens were the gold standard for clinical diagnostic testing. As information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the pandemic continued to be shared, it was clear that the virus could be detected in other specimen types during an active infection. The University of Louisville Infectious Diseases Laboratory accepted non-traditional specimen types, most without a paired, positive NP result, for research purposes only to support local epidemiology efforts. A real-time reverse transcription-polymerase chain reaction (RT-PCR) assay originally validated for NP specimens was used …
What? Now A Respiratory Syncytial Virus Epidemic,
2023
University of Louisville
What? Now A Respiratory Syncytial Virus Epidemic, Aya Allam, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Covid-19 Newsletter (Vol. 153),
2023
Touro College and University System
Covid-19 Newsletter (Vol. 153), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Covid-19 Newsletter (Vol. 152),
2023
Touro College and University System
Covid-19 Newsletter (Vol. 152), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis,
2023
Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo
Articles
The association between current smoking and coronavirus disease 2019 (COVID-19) progression remains uncertain. We aim to provide up-to-date evidence of the role of cigarette smoking in COVID-19 hospitalisation, severity and mortality. On 23 February 2022 we conducted an umbrella review and a traditional systematic review via PubMed/Medline and Web of Science. We used random-effects meta-analyses to derive pooled odds ratios of COVID-19 outcomes for smokers in cohorts of severe acute respiratory syndrome coronavirus 2 infected individuals or COVID-19 patients. We followed the Meta-analysis of Observational Studies in Epidemiology reporting guidelines. PROSPERO: CRD42020207003. 320 publications were included. The pooled odds ratio …
Far-Uvc: Technology Update With An Untapped Potential To Mitigate Airborne Infections,
2023
Roger Williams University
Far-Uvc: Technology Update With An Untapped Potential To Mitigate Airborne Infections, P. Jacob Bueno De Mesquita, Rosemary K. Sokas, Mary B. Rice, Edward A. Nardell
Arts & Sciences Faculty Publications
No abstract provided.
Covid-19 Newsletter (Vol. 151),
2022
Touro College and University System
Covid-19 Newsletter (Vol. 151), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Covid-19 Newsletter (Vol. 150),
2022
Touro College and University System
Covid-19 Newsletter (Vol. 150), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Covid-19 Newsletter (Vol. 149),
2022
Touro College and University System
Covid-19 Newsletter (Vol. 149), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Influenza And Wastewater Surveillance,
2022
University of Nevada, Las Vegas
Influenza And Wastewater Surveillance, Tiffany Familara, Hayley Baker, Anthony Harrington, Ching-Lan Chang
Undergraduate Research Symposium Lightning Talks
Quantitative PCR led to identification of influenza A viral RNA at three schools in Las Vegas, Nevada.
Covid-19 Newsletter (Vol. 148),
2022
Touro College and University System
Covid-19 Newsletter (Vol. 148), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
