Epidemiology Commons^™

Gender Differences In Episodic Memory In Later Life: The Mediating Role Of Education, Sara Robinson

USF Tampa Graduate Theses and Dissertations

In the United States (U.S.), 14 million individuals aged 65+ are expected to be diagnosed with dementia by 2060, and women are nearly twice as likely to be diagnosed. Low education is a well-established risk factor for dementia and is hypothesized to partly explain the gender differences in late-life cognition. However, few studies have investigated education as a mediator of these gender differences. This study aims to investigate education as a mediator of gender differences in episodic memory using longitudinal data from the U.S. Health and Retirement Study (HRS). I used a sample of 35,721 respondents (20,190 women and 15,531 …

Developing An Online Questionnaire To Investigate The Covid-19 Pandemic’S Impacts On Social Isolation And Health In Older Adults Living With Multimorbidity: A Pilot Study, Patricia Nistor

Electronic Thesis and Dissertation Repository

Introduction. Social restrictions preventing the spread of COVID-19 possibly increased social isolation and loneliness. The validity and reliability of a questionnaire assessing the COVID-19 pandemic’s impact on social isolation and loneliness in community dwelling older adults with multimorbidity was investigated.

Methods. A conceptual framework was developed to guide questionnaire construction. Participants were recruited through professional networks, comprising a convenience sample. Feedback interviews assessed usability and face validity. Content validity was assessed using a Content Validity Matrix, and construct validity through tests of association. Reliability of validated scales was assessed using Cronbach’s ⍺. Descriptive statistics and logistic regression were computed. …

Prevalence Of Liver Cirrhosis And Its Association With Obesity Among Mexican Americans: An Evidence Synthesis, Alexa Perlick, Abaigeal Thompson, Colton Wayne, Angel Rendon, Jose E. Campo Maldonado

Research Colloquium

Introduction: Chronic liver disease is the 6^th and 7^th leading cause of death in Hispanic men and Hispanics, respectively.¹ In contrast to other causes of liver disease, the prevalence of nonalcoholic liver disease has been growing as is diabetes and obesity.²

Objective: There is a paucity of data regarding the prevalence of cirrhosis for Mexican Americans in South Texas. The aim of this evidence synthesis is to investigate the prevalence of cirrhosis in Hispanic populations and its relationship with obesity.

Methods: PubMed was used to perform a thorough literature search on September10, 2020. The terms “liver …

Comparative Analysis Of Conformational Dynamics And Systematic Characterization Of Cryptic Pockets In The Sars-Cov-2 Omicron Ba.2, Ba.2.75 And Xbb.1 Spike Complexes With The Ace2 Host Receptor: Confluence Of Binding And Structural Plasticity In Mediating Networks Of Conserved Allosteric Sites, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

In the current study, we explore coarse-grained simulations and atomistic molecular dynamics together with binding energetics scanning and cryptic pocket detection in a comparative examination of conformational landscapes and systematic characterization of allosteric binding sites in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB.1 spike full-length trimer complexes with the host receptor ACE2. Microsecond simulations, Markov state models and mutational scanning of binding energies of the SARS-CoV-2 BA.2 and BA.2.75 receptor binding domain complexes revealed the increased thermodynamic stabilization of the BA.2.75 variant and significant dynamic differences between these Omicron variants. Molecular simulations of the SARS-CoV-2 Omicron spike full-length trimer complexes …

Ut Health Rgv Covid-19 Testing Report, Jefferson T. R. Chandler, Beatriz Tapia

Research Colloquium

Purpose: This health surveillance project's goal was to organize de-identified data received from UT Health RGV with the intent to provide timely reporting to testing sites and health affairs directors. We aimed to explore how testing rates differ between counties, testing sites and age groups from March 30 through August 7, 2020. We looked at different demographics and compared the positivity rates for each testing site. For this report, we will detail information for the pediatric population (ages 0-18).

Materials and Methods: A codebook and database were created with information about COVID-19 test data to formulate reports to the testing …

Epidemiological Algorithm And Early Molecular Testing To Prevent Covid-19 Outbreaks In A Mexican Oncologic Center, Moises González-Escamilla, Diana C. Peréz-Ibave, Carlos H. Burciaga-Flores, Vanessa N. Ortiz-Murillo, Genaro A. Ramírez-Correa, Patricia Rodríguez-Niño, Rafael Piñeiro-Retif, Hazyadee F. Rodríguez-Gutiérrez, Orlando D. Solis-Coronado, Juan F. González-Guerrero, Oscar Vidal-Gutiérrez, María Lourdes Garza-Rodríguez

Research Symposium

Introduction: Prevention strategies and detection of latent COVID-19 infections in oncology staff and oncologic patients are essential to prevent outbreaks in a cancer center. In this study, we used two statistical predictive models in oncology staff and patients from the radiotherapy area to prevent outbreaks and detect COVID-19 cases.

Methods: Staff and patients answered a questionnaire (electronic and paper surveys, respectively) with clinical and epidemiological information. The data was collected through two online survey tools: Real-Time Tracking (R-Track) and Summary of Factors (S-Facts). According to the algorithm's models, cut-off values were established. SARS-CoV-2 qRT-PCR tests confirmed the algorithm's positive individuals. …

Childhood Cancer Survival In The Highly Vulnerable Population Of South Texas: Persistent Challenges For Adolescents And Hispanic Ethnicity, Shenghui Wu, Y. N. Liu, M. Williams, C. Aguilar, A. G. Ramirez, R. Mesa, G. E. Tomlinson

Research Symposium

Background: This study examines childhood cancer survival rates and prognostic factors related to survival in the majority Hispanic population of South Texas (STX), whereas most other population studies in childhood cancer survival focus on populations with relatively few Hispanics.

Methods: The population-based cohort study used Texas Cancer Registry data (1995-2017) to examine survival and prognostic factors.

Results: The 5-year relative survival rate for STX cancer patients diagnosed at 0–19 years was 80.3% for all races/ethnicity. Hispanics had statistically significant lower 5-year relative survival rates than non-Hispanic Whites (NHW) for male and female together diagnosed at age ≥ 5 years. When …

Characterization Of Oral Cavity And Oropharyngeal Cancer In The Texas Rio Grande Valley, Jared A. Sperling, Rachel Giese

Research Symposium

Background: Cancers of the oral cavity (OC) and oropharynx (OP) account for 3% of cancers diagnosed in the United States each year. A primary cause of death among the Hispanic population in the United States is cancer, accounting for 20% of annual mortality. The Rio Grande Valley (RGV) is a medically-underserved area of South Texas with a large Hispanic population facing health disparities. In this study, we examine the incidence and mortality of OC and OP cancer in the RGV.

Methods: CDC population-level incidence and mortality rate per 100,000 of OC/OP cancer among patients in the RGV counties of Hidalgo …

Awareness Of Genetic Testing For High-Risk Cancer Among Different Racial Groups In The United States, Okechukwu C. Erinne, Modupe O. Onigbogi

Research Symposium

Background: Genetic testing for high-risk cancer can provide information on personal risk of developing cancer, as well as diagnosis, prognosis and treatment once cancer has been detected.

Methods: Data for this study were obtained from the Health Information National Trends (HINTS 5, Cycle 4), conducted among U.S. adults (age ≥ 18 years) from February 24 to June 20, 2020. An equal probability sample of addresses were stratified, and an adult was selected from each household. Data analysis was conducted 3,865 respondents who completed the survey. The primary outcome was awareness of genetic testing for high-risk cancer (GTHC). We …

Clinical Characteristics And Risk Factors For Mortality During The 'First Wave' Of Covid-19 In Reynosa, Tamaulipas, Luis G. Vargas Garcia, Francisco E. Díaz Cisneros, Antonio Gutiérrez Sierra, Juan Rosales Martínez, Manlio F. Lara Duck, Netzahualcoyotl Mayek Pérez

Research Symposium

Background: The COVID-19 pandemic has impacted public health in Mexico. As of February 2020, there have been at least four "waves" of contagion that resulted in 5.82 million positive cases and more than 325 thousand deaths. At the beginning of the COVID-19 pandemic, hospital and population-based information was available, frequently with non-specific symptoms. Little was known about the risk factors for mortality in specific conditions. We described the clinical characteristics of patients with COVID-19 in Reynosa, Tamaulipas during 2020 and identified the risk factors for mortality.

Methods: The COVID-19 cases registered from March to November 2020 in Reynosa were divided …

Quality Of Nutritional Care During Pregnancy: Folic Acid And Vitamin D Supplementation, Isabel Omaña-Guzmán, Monica Ancira-Moreno, Cecilia Pérez-Navarro, Sonia Hernández-Cordero, Soraya Burrola Méndez, Eric Monterrubio-Flores, Arturo Bautista Morales, Omar Acosta Ruiz, Constanza Bernat, Belén Sánchez,, Ariana Cajero

Research Symposium

Backgrounds: Folic acid (FA) and vitamin D supplementation is recommended during pregnancy. Quality nutritional care during pregnancy should include the supplementation of these vitamins. Therefore, the aim of this study was to assess the quality of nutritional care regarding supplementation during pregnancy in primary health care units in six states of Mexico (Estado de México, Oaxaca, Yucatán, Chihuahua, Veracruz and Chiapas).

Methods: A mixed study was conducted. An indicator (formed by two sub-indicators) to assess the quality of nutritional care focused on FA and vitamin D supplementation in pregnancy was developed and validated. To assess the quality of care, a …

Exploring Conformational Landscapes And Cryptic Binding Pockets In Distinct Functional States Of The Sars-Cov-2 Omicron Ba.1 And Ba.2 Trimers: Mutation-Induced Modulation Of Protein Dynamics And Network-Guided Prediction Of Variant-Specific Allosteric Binding Sites, Gennady M. Verkhivker, Mohammed Alshahrani, Grace Gupta

Mathematics, Physics, and Computer Science Faculty Articles and Research

A significant body of experimental structures of SARS-CoV-2 spike trimers for the BA.1 and BA.2 variants revealed a considerable plasticity of the spike protein and the emergence of druggable binding pockets. Understanding the interplay of conformational dynamics changes induced by the Omicron variants and the identification of cryptic dynamic binding pockets in the S protein is of paramount importance as exploring broad-spectrum antiviral agents to combat the emerging variants is imperative. In the current study, we explore conformational landscapes and characterize the universe of binding pockets in multiple open and closed functional spike states of the BA.1 and BA.2 Omicron …

Sugar-Sweetened Beverages And Artificially Sweetened Beverages Consumption And The Risk Of Nonalcoholic Fatty Liver (Nafld) And Nonalcoholic Steatohepatitis (Nash), Tung Sung Tseng, Wei Ting Lin, Peng Sheng Ting, Chiung Kuei Huang, Po Hung Chen, Gabrielle V. Gonzalez, Hui Yi Lin

School of Public Health Faculty Publications

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years …

Factors Associated With The Prevalence Of Hiv Infection In Haiti Among Women Of Childbearing Age - National Survey On Morbidity, Mortality, And Use Of Services, 2016-2017., Yves Sanley Thimothee

AMNET XX Conferencia Internacional

Abstract of an observational study on HIV prevalence in Haitian women of childbearing age from 2016 to 2017.

Type 2 Diabetes Mellitus Burden Of Disease In Brazil Between 1990 To 2019: A Nationwide Descriptive Analysis Of The Global Burden Of Disease Study 2019, Lucas Helal, Paula Portal Teixeira, Lucas Scotta Cabral, Tiago Montes, Rita Mattiello, Bárbara Niégia Garcia De Goulart, Bruce Bartholow Duncan

AMNET XX Conferencia Internacional

This is a Brazilian nationwide analysis of the burden of type 2 diabetes mellitus along the 26 states and federal district, between 1990 up to 2019. In summary, through spatiotemporal Gaussian regression methods, we estimated the attributable share of T2DM for prevalence, deaths, DALYs, YLLs and YLDs in Brazilian population. Moreover, we sought to investigate the behavior of top risk factors for T2DM and the attributable impact in burden of disease outcomes accordingly. We also investigated whether the geolocation and time, as well as the socio demographic index, would have any ecological relationship with different levels of disease and risk …

Mortalidade Prematura (30-69 Anos) Por Doenças Crônicas Não Transmissíveis (Dcnt) No Rio Grande Do Sul (Rs) Entre 2012 E 2022, Segundo O Sexo: Estudo Ecológico, Jonatan Da Rosa Pereira Da Silva

AMNET XX Conferencia Internacional

OBJETIVO

Analisar a taxa de mortalidade prematura por DCNT no RS, segundo o sexo, entre os anos de 2012 e 2022.

MÉTODO

A taxa de mortalidade prematura por DCNT foi calculada por meio da razão entre o número de óbitos prematuros por DCNT no Estado (provenientes do Painel de Monitoramento da Mortalidade Prematura por DCNT do Ministério da Saúde (MS)) e a estimativa populacional da faixa etária de 30 a 69 anos (fornecidas pelo Departamento de Economia e Estatística (DEE) do RS), multiplicado por 100.000 habitantes, considerando estratificações por sexo e ano de ocorrência dos óbitos. Adicionalmente, foi realizado o …

Asociación Geoespacial Entre Variables Clínicas Y Sociodemográficas Y El Control De La Hemoglobina Glicosilada En Pacientes Colombianos Con Diagnóstico De Diabetes. Un Estudio De Fuente Secundaria A Nivel Departamental., Juan Pablo Pérez Bedoya, Lina Marcela Ruiz Galvis, Elizabeth Herrera Franco, Flor Enid Taparcua Cardona, Oscar Ignacio Mendoza Cardozo, Carlos Andrés Pérez Aguirre, Noël Christopher Barengo, Paula Andrea Diaz Valencia

AMNET XX Conferencia Internacional

Objetivo: Examinar la asociación espacial a nivel departamental entre variables clínicas/sociodemográficas y el porcentaje de pacientes con diabetes que presentan un nivel de hemoglobina glicosilada (HbA1c) < 7%.

Métodos: Estudio ecológico de fuentes secundarias con datos agregados a nivel departamental, obtenidos del Instituto de Estadística y de la Cuenta de Alto Costo para el año 2021. Se recolectó información sobre la proporción de pacientes con diabetes que presentaban un índice de masa corporal (IMC) de 20 a 25 kg/m², lipoproteína de baja densidad (LDL) < 100 mg/dl, presión arterial (PA) < 140/90 mmHg, HbA1c < 7% y el índice de pobreza multidimensional (IPM). Calculamos estadísticos locales de asociación espacial con matriz de contigüidad tipo reina de primer orden y un nivel de pseudosignificación del 0,05.

Resultados: Todas las variables analizadas presentaron autocorrelación espacial con un I de Morán global positivo y …

Relação Entre Mortalidade Prematura Por Doenças Crônicas Não Transmissíveis E Cobertura De Atenção Primária No Rio Grande Do Sul: Um Estudo Ecológico, Beatriz Raffi Lerm

AMNET XX Conferencia Internacional

OBJETIVO

Mensurar a correlação entre a taxa de mortalidade prematura por Doenças Crônicas Não Transmissíveis (DCNT) e a cobertura de Atenção Primária à Saúde (APS) dos municípios do Rio Grande do Sul (RS).

METODOLOGIA

A taxa de mortalidade prematura (30 a 69 anos) por DCNT dos municípios foi calculada através da razão entre o número de óbitos prematuros de residentes por DCNT de 2021 (provenientes do Painel de Monitoramento da Mortalidade Prematura por DCNT do Ministério da Saúde (MS)) e a estimativa populacional da faixa etária de 30 a 69 anos de 2021 (fornecidas pelo Departamento de Economia e Estatística …

Tobacco, Alcohol And Diet As Mortality Risk Factors: The Secondary Analysis Of The 25-Year Cohort Study, Alina Egorova, Bulat Idrisov, Romany Redman, Stanislav Otstavnov, Sergey Soshnikov

Journal of Health Research

Background: Individual lifestyle risk factors have been linked to increased mortality globally; however, there is limited data on these associations in Russia. A secondary analysis of the Russia Longitudinal Monitoring Survey (RLMS) data was conducted to close this gap.

Methods: The secondary data have been obtained from a nationally-representative annual cohort survey conducted by the Higher School of Economics (HSE). In this original study, for the first time in Russia, we extracted RRs for researched risk factors. Of additional original value, we made a prospective-retrospective cohort based on a representative longitudinal survey and provided the deaths as outcomes for survival …

History And Current Status Of Mediterranean Spotted Fever (Msf) In The Crimean Peninsula And Neighboring Regions Along The Black Sea Coast, Muniver T. Gafarova, Marina E. Eremeeva

Department of Biostatistics, Epidemiology, and Environmental Health Sciences Faculty Publications

Mediterranean spotted fever (MSF) is a tick-borne rickettsiosis caused by Rickettsia conorii subspecies conorii and transmitted to humans by Rhipicephalus sanguineus ticks. The disease was first discovered in Tunisia in 1910 and was subsequently reported from other Mediterranean countries. The first cases of MSF in the former Soviet Union were detected in 1936 on the Crimean Peninsula. This review summarizes the historic information and main features of MSF in that region and contemporary surveillance and control efforts for this rickettsiosis. Current data pertinent to the epidemiology of the disease, circulation of the ticks and distribution of animal hosts are discussed …