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Epidemiologic Survey Of Legionella Urine Antigen Testing Within A Large Wisconsin-Based Health Care System, Caroline P. Toberna, Hannah M. William, Jessica J. F. Kram, Kayla Heslin, Dennis J. Baumgardner 2020 Aurora Research Institute; Center for Urban Population Health; Aurora UW Medical Group, Aurora Health Care

Epidemiologic Survey Of Legionella Urine Antigen Testing Within A Large Wisconsin-Based Health Care System, Caroline P. Toberna, Hannah M. William, Jessica J. F. Kram, Kayla Heslin, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Purpose: Legionella pneumophila pneumonia is a life-threatening, environmentally acquired infection identifiable via Legionella urine antigen tests (LUAT). We aimed to identify cumulative incidence, demographic distribution, and undetected disease outbreaks of Legionella pneumonia via positive LUAT in a single eastern Wisconsin health system, with a focus on urban Milwaukee County.

Methods: A multilevel descriptive ecologic study was conducted utilizing electronic medical record data from a large integrated health care system of patients who underwent LUAT from 2013 to 2017. A random sample inclusive of all positive tests was reviewed to investigate geodemographic differences among patients testing positive versus negative. Statistical comparisons ...


Effect Of Poverty Level On The Relationship Between Hyperlipidemia And Cardiorenal Syndrome, Sri K. Banerjee MD, PhD, Raymond Panas, James Diegel, Karen Banerjee 2020 Walden University, Core Faculty, Program Director Designee, College of Health Sciences

Effect Of Poverty Level On The Relationship Between Hyperlipidemia And Cardiorenal Syndrome, Sri K. Banerjee Md, Phd, Raymond Panas, James Diegel, Karen Banerjee

Journal of Health Disparities Research and Practice

Purpose. Elevated cholesterol is known to be associated with chronic kidney disease (CKD) and cardiovascular disease (CVD) independently. Cardiorenal syndrome (CRS), a recently defined syndrome, is characterized by renal failure that is closely interrelated to cardiac dysfunction. The effect of socioeconomic status on cardiorenal syndrome has not been explored in a multi-ethnic population. In this retrospective secondary analysis, the hypothesis was tested if socioeconomic status modifies the effect of hyperlipidemia on CRS.

Methods. The National Health and Nutrition Examination Survey (NHANES) is a cross sectional survey done on the non-institutionalized population of the United States. All patients from the NHANES ...


Vaccines In Current Culture: The Hpv Vaccine Controversy, Alyssa Johnston 2020 Liberty University

Vaccines In Current Culture: The Hpv Vaccine Controversy, Alyssa Johnston

Senior Honors Theses

The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care. However, the fear of risks related to vaccines has been partially responsible for the decisions of many parents to delay or avoid vaccinating their children. The human papilloma virus (HPV) vaccine specifically is one of the most controversial vaccines in current culture due to reports of new onset or exacerbation of autoimmune diseases, infertility, and even death following its administration. This review synthesizes information regarding the relevance and safety of the HPV vaccine, as well ...


Alcohol_Focused Drowning Prevention Campaigns: What Do We Know And What Should We Do Now?, Hannah Calverley, Lauren Petrass, Jennifer Blitvich 2020 Federation University, Austalia

Alcohol_Focused Drowning Prevention Campaigns: What Do We Know And What Should We Do Now?, Hannah Calverley, Lauren Petrass, Jennifer Blitvich

International Journal of Aquatic Research and Education

Alcohol and drugs have been identified as key risk factors for youth (aged 15-24 years) and adult drownings in high-income countries (HIC). Whilst alcohol specific drowning prevention education programs have been developed and implemented, youth continue to be over-represented in drowning statistics, including those linked with alcohol. Therefore, this project aimed to: (i) review and assess all alcohol themed drowning prevention campaigns within HICs; (ii) determine whether the campaign had undergone evaluation for effectiveness; and (iii) provide recommendations to improve the effectiveness of future interventions. For each of the eighty-one HICs identified for the 2019 fiscal year, searches of peer-reviewed ...


Socio-Ecological Nature Of Drowning In Low- And Middle-Income Countries: A Review To Inform Health Promotion Approaches, Muthia Cenderadewi, Richard Charles Franklin, Susan Devine 2020 James Cook University, Australia; the University of Mataram, Indonesia

Socio-Ecological Nature Of Drowning In Low- And Middle-Income Countries: A Review To Inform Health Promotion Approaches, Muthia Cenderadewi, Richard Charles Franklin, Susan Devine

International Journal of Aquatic Research and Education

Most deaths by drowning (91%) have occurred in low- and middle-income countries (LMICs), particularly in Southeast Asia (35%) and Africa (20%), in proportion to total drowning deaths worldwide. Poor data collection in LMICs hinders the planning, implementation, and evaluation of prevention strategies. The objective of this study was to review the rates and risk factors of unintentional drowning in LMICs and to identify drowning prevention strategies within a socio-ecological health promotion framework. A systematic search, guided by PRISMA, was conducted on Ovid MEDLINE, CINAHL, Informit health, PsycINFO (ProQuest), Scopus, SafetyLit, Google Scholar, and BioMed Central databases for all relevant studies ...


Novel Coronavirus (2019-Ncov) In Disguise, Qian Zhang, Annyella Douglas, Zain U. Abideen, Shristi Khanal, Stephanie Tzarnas 2020 Thomas Jefferson University

Novel Coronavirus (2019-Ncov) In Disguise, Qian Zhang, Annyella Douglas, Zain U. Abideen, Shristi Khanal, Stephanie Tzarnas

Abington Jefferson Health Papers

Novel coronavirus (2019-nCoV) pandemic is currently one of the most influential topics as it not only impacts the field of medicine but most importantly, it affects the lives of many individuals throughout the world. We report an interesting 2019-nCoV case in a tertiary community hospital with the initial concern of acute pyelonephritis without respiratory symptoms that ultimately led to the quarantine of a number of healthcare providers. This case emphasizes the importance of radiological evidence in diagnosing 2019-nCoV in the setting of an initial atypical presentation. It also serves as an example of how healthcare providers may need to increase ...


Covid-19 And Severe Acute Respiratory Infection, Steven C. Hatch 2020 University of Massachusetts Medical School

Covid-19 And Severe Acute Respiratory Infection, Steven C. Hatch

PEER Liberia Project

This presentation provides an overview of Severe Acute Respiratory Infection (SARI) and COVID-19, with following objectives: characterize current & near-future epidemiology of COVID-19 outbreak; provide general clinical features of SARI due to COVID; outline clinical management of COVID.


Covid-19 In The Pediatric Population, Patricia A. McQuilkin 2020 University of Massachusetts Medical School

Covid-19 In The Pediatric Population, Patricia A. Mcquilkin

PEER Liberia Project

This presentation provides an overview of a recent study and its implications pertaining to COVID-19 for pediatric patients.


Coronavirus Disease 2019 (Covid-19), Matthew Dunbar 2020 Ohio Northern University

Coronavirus Disease 2019 (Covid-19), Matthew Dunbar

Pharmacy Student Scholarship

No abstract provided.


The Association Between Patient-Reported Clinical Factors And 30-Day Acute Care Utilization In Chronic Heart Failure, Jinying Chen, Rajani S. Sadasivam, Amanda C. Blok, Christine S. Ritchie, Catherine S. Nagawa, Elizabeth Aaker Orvek, Kanan Patel, Thomas K. Houston 2020 University of Massachusetts Medical School

The Association Between Patient-Reported Clinical Factors And 30-Day Acute Care Utilization In Chronic Heart Failure, Jinying Chen, Rajani S. Sadasivam, Amanda C. Blok, Christine S. Ritchie, Catherine S. Nagawa, Elizabeth Aaker Orvek, Kanan Patel, Thomas K. Houston

Population and Quantitative Health Sciences Publications

BACKGROUND: Heart failure patients have high rates of repeat acute care use. Current efforts for risk prediction often ignore postdischarge data.

OBJECTIVE: To identify postdischarge patient-reported clinical factors associated with repeat acute care use.

RESEARCH DESIGN: In a prospective cohort study that followed patients with chronic heart failure for 30 days postdischarge, for 7 days after discharge (or fewer days if patients used acute care within 7 days postdischarge), patients reported health status, heart failure symptoms, medication management, knowledge of follow-up plans, and other issues using a daily interactive automatic phone call.

SUBJECTS: A total of 156 patients who had ...


Vaccine Confidence, Coverage, And Hesitancy Worldwide: A Literature Analysis Of Vaccine Hesitancy And Potential Causes Worldwide, Jordan Hammond 2020 University of South Carolina - Columbia

Vaccine Confidence, Coverage, And Hesitancy Worldwide: A Literature Analysis Of Vaccine Hesitancy And Potential Causes Worldwide, Jordan Hammond

Senior Theses

Vaccines are one of the world’s most impactful medical therapies. They are cost-effective, successfully proven, and one of the quickest treatment options available today (Clark et al., 2016). They save millions of lives every year and have eliminated certain diseases on a national and international level. However, millions of people worldwide still remain unvaccinated. In developed nations, mainly The United States (U.S.) and the European countries, many of the unvaccinated are a result of rising vaccine hesitancy of parents in conjunction with the anti-vaccination movement. Vaccine hesitancy is defined as “a delay in acceptance or refusal of vaccines ...


Investigating The Impact Of Asymptomatic Carriers On Covid-19 Transmission, Jacob B. Aguilar, Jeremy Samuel Faust, Lauren M. Westafer, Juan B. Gutierrez 2020 Saint Leo University

Investigating The Impact Of Asymptomatic Carriers On Covid-19 Transmission, Jacob B. Aguilar, Jeremy Samuel Faust, Lauren M. Westafer, Juan B. Gutierrez

Coronavirus COVID-19 Publications by UMMS Authors

Coronavirus disease 2019 (COVID-19) is a novel human respiratory disease caused by the SARS-CoV-2 virus. Asymptomatic carriers of the virus display no clinical symptoms but are known to be contagious. Recent evidence reveals that this sub-population, as well as persons with mild, represent a major contributor in the propagation of COVID-19. The asymptomatic sub-population frequently escapes detection by public health surveillance systems. Because of this, the currently accepted estimates of the basic reproduction number (Ro) of the virus are inaccurate. It is unlikely that a pathogen can blanket the planet in three months with an Ro in the vicinity of ...


First Aid First: Implementation And Evaluation Of A Community-Based First Aid Training Course, Luke Wesemann 2020 Wayne State University

First Aid First: Implementation And Evaluation Of A Community-Based First Aid Training Course, Luke Wesemann

Medical Student Research Symposium

In 2018, medical students at Wayne State University School of Medicine (WSUSOM) created a first aid training initiative called First Aid First (FAF). FAF is a comprehensive community-based training program that teaches lifesaving skills tailored for Detroit. The objective of this initiative was to improve the confidence and basic first aid skills of those who attend trainings.

Pre- and post-test surveys were used to measure knowledge, confidence and skill level. The survey data gathered from March 2018-October 2019 consisted of 5 Likert scale questions for self-evaluation component and 23-25 multiple choice questions, number depending on time of administration due to ...


Simulation-Based Power And Sample Size Calculation For Designing Interrupted Time Series Analyses Of Count Outcomes In Evaluation Of Health Policy Interventions, Wei Liu, Shangyuan Ye, Bruce A. Barton, Melissa A. Fischer, Colleen Lawrence, Elizabeth J. Rahn, Maria I. Danila, Kenneth G. Saag, Paul A. Harris, Stephenie C. Lemon, Jeroan J. Allison, Bo Zhang 2020 Harbin Institute of Technology

Simulation-Based Power And Sample Size Calculation For Designing Interrupted Time Series Analyses Of Count Outcomes In Evaluation Of Health Policy Interventions, Wei Liu, Shangyuan Ye, Bruce A. Barton, Melissa A. Fischer, Colleen Lawrence, Elizabeth J. Rahn, Maria I. Danila, Kenneth G. Saag, Paul A. Harris, Stephenie C. Lemon, Jeroan J. Allison, Bo Zhang

Population and Quantitative Health Sciences Publications

Objective: The purpose of this study was to present the design, model, and data analysis of an interrupted time series (ITS) model applied to evaluate the impact of health policy, systems, or environmental interventions using count outcomes. Simulation methods were used to conduct power and sample size calculations for these studies.

Methods: We proposed the models and analyses of ITS designs for count outcomes using the Strengthening Translational Research in Diverse Enrollment (STRIDE) study as an example. The models we used were observation-driven models, which bundle a lagged term on the conditional mean of the outcome for a time series ...


Changing Trends In The Landscape Of Patients Hospitalized With Acute Myocardial Infarction (2001 To 2011) (From The Worcester Heart Attack Study), Regino Mercado-Lubo, Jorge Yarzebski, Darleen M. Lessard, Joel M. Gore, Robert J. Goldberg 2020 University of Massachusetts Medical School

Changing Trends In The Landscape Of Patients Hospitalized With Acute Myocardial Infarction (2001 To 2011) (From The Worcester Heart Attack Study), Regino Mercado-Lubo, Jorge Yarzebski, Darleen M. Lessard, Joel M. Gore, Robert J. Goldberg

Population and Quantitative Health Sciences Publications

During the past several decades, new diagnostic tools, interventional approaches, and population-wide changes in the major coronary risk factors have taken place. However, few studies have examined relatively recent trends in the demographic characteristics, clinical profile, and the short-term outcomes of patients hospitalized for acute myocardial infarction (AMI) from the more generalizable perspective of a population-based investigation. We examined decade long trends (2001 to 2011) in patient's demographic and clinical characteristics, treatment practices, and hospital outcomes among residents of the Worcester metropolitan area hospitalized with an initial AMI (n=3,730) at all 11 greater Worcester medical centers during ...


Combining Genomics And Epidemiology To Track Mumps Virus Transmission In The United States, Shirlee Wohl, Lawrence C. Madoff, Bronwyn L. MacInnis 2020 Harvard University

Combining Genomics And Epidemiology To Track Mumps Virus Transmission In The United States, Shirlee Wohl, Lawrence C. Madoff, Bronwyn L. Macinnis

Open Access Articles

Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks. We paired epidemiological data from public health investigations with analysis of mumps virus whole genome sequences from 201 infected individuals, focusing on Massachusetts university communities. Our analysis suggests continuous, undetected circulation of mumps locally and nationally, including multiple independent introductions into Massachusetts and into individual communities. Despite the presence of these multiple mumps virus lineages, the genomic data show that one lineage has dominated in the US since at least 2006 ...


Seek And You Shall Find: Is Routine Duplex Ultrasound Screening For Deep Vein Thrombosis In Trauma Warranted?, Ashley Thompson MD, Krista Miller MD, Tatiana R. Eversley-Kelso MPH, Eric Shaw PhD, James Dunne MD, Heather MacNew MD, FACS 2020 HCA Healthcare

Seek And You Shall Find: Is Routine Duplex Ultrasound Screening For Deep Vein Thrombosis In Trauma Warranted?, Ashley Thompson Md, Krista Miller Md, Tatiana R. Eversley-Kelso Mph, Eric Shaw Phd, James Dunne Md, Heather Macnew Md, Facs

General Surgery

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Identifying Unreliable Predictions In Clinical Risk Models, Paul D. Myers, Kenney Ng, Kristen Severson, Uri Kartoun, Wangzhi Dai, Wei Huang, Frederick A. Anderson Jr., Collin M. Stultz 2020 Massachusetts Institute of Technology

Identifying Unreliable Predictions In Clinical Risk Models, Paul D. Myers, Kenney Ng, Kristen Severson, Uri Kartoun, Wangzhi Dai, Wei Huang, Frederick A. Anderson Jr., Collin M. Stultz

Open Access Articles

The ability to identify patients who are likely to have an adverse outcome is an essential component of good clinical care. Therefore, predictive risk stratification models play an important role in clinical decision making. Determining whether a given predictive model is suitable for clinical use usually involves evaluating the model's performance on large patient datasets using standard statistical measures of success (e.g., accuracy, discriminatory ability). However, as these metrics correspond to averages over patients who have a range of different characteristics, it is difficult to discern whether an individual prediction on a given patient should be trusted using ...


Trajectories Of Health-Related Quality Of Life And Hba1c Values Of Children And Adolescents With Diabetes Mellitus Type 1 Over 6 Months: A Longitudinal Observational Study, Kathrin I. Fischer, Felix H. Fischer, Dana Barthel, Christiane Otto, Ute Thyen, Marcus Klein, Otto Walter, Ulrike Ravens-Sieberer, Matthias S. F. Rose, Sandra Nolte 2020 Free University of Berlin

Trajectories Of Health-Related Quality Of Life And Hba1c Values Of Children And Adolescents With Diabetes Mellitus Type 1 Over 6 Months: A Longitudinal Observational Study, Kathrin I. Fischer, Felix H. Fischer, Dana Barthel, Christiane Otto, Ute Thyen, Marcus Klein, Otto Walter, Ulrike Ravens-Sieberer, Matthias S. F. Rose, Sandra Nolte

Open Access Articles

Introduction: To achieve optimized blood glucose concentrations (assessed by HbA1c) and high health-related quality of life (HRQL), children and adolescents with diabetes mellitus type 1 (T1DM) must follow strict disease management strategies. This study aims to investigate HRQL of children and adolescents with T1DM and its association with HbA1c values over the course of 6 months.

Methods: Patients aged 7-17 years (n = 203) with T1DM provided HRQL data on a monthly basis. HRQL was measured using the Kids-CAT, a computer-adaptive test (CAT) comprising five generic HRQL domains. HbA1c concentrations were assessed at baseline, at 3 and 6 months. We explored ...


Patient-Reported Outcomes Feedback Report For Knee Arthroplasty Patients Should Present Selective Information In A Simple Design - Findings Of A Qualitative Study, Kathrin I. Fischer, Diarmuid De Faoite, Matthias S. F. Rose 2020 Charité – Universitätsmedizin Berlin

Patient-Reported Outcomes Feedback Report For Knee Arthroplasty Patients Should Present Selective Information In A Simple Design - Findings Of A Qualitative Study, Kathrin I. Fischer, Diarmuid De Faoite, Matthias S. F. Rose

Open Access Articles

BACKGROUND: Technical innovation to assess patient-reported outcomes (PROs) facilitates their implementation in clinical practice. In particular, mobile applications (apps) allow PROs to be assessed outside of the clinical setting. A patient's health status can be remotely monitored and evaluated after discharge, and their recovery process tracked. This is of particular interest for patients after knee arthroplasty, as the recovery phase after surgery usually takes place in an outpatient setting and requires a high level of patient engagement. Providing results of PRO assessments to patients in the form of a feedback report could increase patient engagement and may improve communication ...


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