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Oxytocin Promotes Face-Sensitive Neural Responses To Infant And Adult Faces In Mothers, Mikko J. Peltola, Lane Strathearn, Kaija Puura 2018 University of Iowa

Oxytocin Promotes Face-Sensitive Neural Responses To Infant And Adult Faces In Mothers, Mikko J. Peltola, Lane Strathearn, Kaija Puura

Stead Family Department of Pediatrics Publications

Research utilizing intranasal oxytocin (OT) administration has shown that OT may increase attention and sensitivity to social cues, such as faces. Given the pivotal role of OT in parental behaviors across mammals, the paucity of intranasal OT research investigating responses to social cues in parents and particularly mothers of young children is a critical limitation. In the current study, we recorded cortical event-related potentials (ERPs) to investigate whether intranasal OT affects the early neural responses to emotional faces in mothers of 1-year-old infants. Using a double-blind, within-subjects design, mothers (n = 38) were administered intranasal OT and placebo on separate sessions ...


Measuring Physiological Responses To Sensation In Typical Adults, Sarah Button, Kristen Christensen, Emily Minor 2018 Dominican University of California

Measuring Physiological Responses To Sensation In Typical Adults, Sarah Button, Kristen Christensen, Emily Minor

Master's Theses and Capstone Projects

Objective: Sensory processing issues can have a large negative impact on the ability to participate in daily occupations such as ADLs, access to work, school and leisure environments, and social interactions (Dunn, 2001). The evidence documenting sensory processing issues in adults is sparse. Physiological information can be used as objective evidence to support the claim that those with over-responsivity to sensations are experiencing their environment differently than the typical population. Understanding more about sensory processing in adults may lead to increased recognition of the problem and more opportunities for intervention to increase occupational participation. The purpose of this quantitative study ...


Post-Traumatic Stress Disorder: Review Of Dsm Criteria And Functional Neuroanatomy, Cornelius W. Thomas 2018 Huntington VA Medical Center

Post-Traumatic Stress Disorder: Review Of Dsm Criteria And Functional Neuroanatomy, Cornelius W. Thomas

Marshall Journal of Medicine

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for post-traumatic stress disorder (PTSD) consist of over twenty possible symptoms that can be divided into six broad categories. These categories correlate with specific brain networks that regulate emotions, behaviors, and autonomic function. Normal functioning of these networks depends on two key regions; the prefrontal cortex and the amygdala. The prefrontal cortex provides top-down executive control over amygdala, whereas the amygdala is critical for threat detection and activation of the ‘fight or flight’ response. Events that trigger extreme and/or prolonged fear can cause persisting dysregulation within the prefrontal-amygdala circuit ...


Expressive Arts Group Therapy With Children And Adolescents Who Have Experienced Trauma, Shade Alfred 2018 Lesley University

Expressive Arts Group Therapy With Children And Adolescents Who Have Experienced Trauma, Shade Alfred

Expressive Therapies Capstone Theses

Experiencing traumatic situations is an inevitable part of life that many have struggled to understand and have difficulty working through its effects. This results in persons seeking therapy to better cope and heal from the impact of the traumatic experience. Children and adolescents who are considered vulnerable require more assistance to help them when they have encountered a traumatic experience. Research has highlighted that Expressive Arts Therapies is a favorable treatment option used with traumatized children and adolescents. Hence, this paper reflects research that has been conducted on group expressive arts therapy with children and adolescents who have experienced trauma ...


'No Pink Ribbons': How Women's Lived Experiences With Breast Atypia Inform Decisions Involving Risk-Reducing Medications, Sarah L. Goff, Reva Kleppel, Grace Makari-Judson 2018 University of Massachusetts Medical School - Baystate

'No Pink Ribbons': How Women's Lived Experiences With Breast Atypia Inform Decisions Involving Risk-Reducing Medications, Sarah L. Goff, Reva Kleppel, Grace Makari-Judson

Journal of Patient-Centered Research and Reviews

Purpose: Atypical hyperplasia (AH) is associated with a nearly 4-fold elevation of lifetime risk for breast cancer, and lobular carcinoma in situ (LCIS) is associated with a 7- to 8-fold risk. Women with AH/LCIS make numerous decisions in the course of treatment, including whether to take a risk-reducing medication, an option relatively few women pursue. We explored women’s decision-making processes through patient narratives in an effort to inform decision supports for AH/LCIS.

Methods: We conducted in-depth interviews with 20 English-speaking women with AH/LCIS and no subsequent diagnosis of invasive breast cancer who had enrolled in the ...


Uncertainty And Competing Priorities In Shared Clinical Decision-Making, Dennis J. Baumgardner 2018 Aurora UW Medical Group, Aurora Health Care

Uncertainty And Competing Priorities In Shared Clinical Decision-Making, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

In this issue introduction, the editor-in-chief of Journal of Patient-Centered Research and Reviews observes that a connecting thread among the articles published therein is an element of uncertainty among patients and clinicians. Competing priorities for the patient also may be present. Several approaches to overcoming these prevalent conflicts to delivery of better health care have been proposed, the most important of which may be clinicians embracing a will to practice shared decision-making.


A Framework For Conceptualizing How Narratives From Health-Care Consumers Might Improve Or Impede The Use Of Information About Provider Quality, Melissa L. Finucane, Steven C. Martino, Andrew M. Parker, Mark Schlesinger, Rachel Grob, Jennifer L. Cerully, Lise Rybowski, Dale Shaller 2018 RAND Corporation

A Framework For Conceptualizing How Narratives From Health-Care Consumers Might Improve Or Impede The Use Of Information About Provider Quality, Melissa L. Finucane, Steven C. Martino, Andrew M. Parker, Mark Schlesinger, Rachel Grob, Jennifer L. Cerully, Lise Rybowski, Dale Shaller

Patient Experience Journal

Consumers choosing a health-care provider have access to diverse information including narratives by patients about their prior experiences. However, little research has examined how narratives might improve or impede the use of information about the quality of providers’ performance. This paper describes a conceptual framework for examining mechanisms by which narrative information might influence consumer judgments and decisions about providers. We conducted a conceptual review of risk communication and behavioral decision research. We synthesized the literature to form the foundation of a conceptual framework for assessing how narrative information about provider quality impacts consumer decisions about providers. We identified four ...


Science, Mental Illness, And Ethics In Friedrich Dürrenmatt’S The Physicists, Niyant Vora 2018 Illinois Wesleyan University

Science, Mental Illness, And Ethics In Friedrich Dürrenmatt’S The Physicists, Niyant Vora

John Wesley Powell Student Research Conference

In 1962, as Cold War tensions approached their peak, Friedrich Dürrenmatt, a Swiss playwright, published his play The Physicists. Two of the most important topics in The Physicists are mental illness and ethical responsibility of scientists. Dürrenmatt’s three main characters: Möbius (a genius), Einstein (a Russian spy), and Newton (an American spy) are all physicists who appropriate the status of mentally ill in order to hide from society inside the Les Cerisiers Sanatorium. Their status as mentally ill acts as a cover up that reveals their different reasons for adapting that status–from Möbius attempt to escape the politics ...


Effects Of Psychiatric Comorbidities On The Perioperative Outcomes Following A Primary Total Arthroplasty, Taylor Smith 2018 Carroll College

Effects Of Psychiatric Comorbidities On The Perioperative Outcomes Following A Primary Total Arthroplasty, Taylor Smith

Carroll College Student Undergraduate Research Festival

This review was conducted to compare the perioperative outcomes following a total primary arthroplasty among patients with a psychiatric comorbidity versus those without a psychiatric comorbidity. Literature was reviewed from the database Pubmed. Seven cohort and case-control studies were reviewed, with the largest sample size of 8.4 million patients. Psychiatric comorbidities resulted in increased negative perioperative outcomes compared to patients without psychiatric comorbidities in six articles. These studies observed higher rates of revision, blood transfusion, mortality, non-traditional discharge, and increased length and cost of stay for patients with a diagnosed psychiatric condition. Therefore, it was concluded from most studies ...


The Relation Of Seasonal Patterns To Mood Changes And Gender Differences In College-Aged Students, mariah meza 2018 Dominican University of California

The Relation Of Seasonal Patterns To Mood Changes And Gender Differences In College-Aged Students, Mariah Meza

Student Research Posters

This study examined college students’ moods during different seasons patterns throughout the year. Previous research has indicated that many individuals feel more lethargic, lonely and moody during the winter months (Rohan & Sigmon, 2000). These mood and behavior patterns clearly depend on specific seasons of the year. However, many studies have produced inconsistent findings and current data on how weather impacts college aged students moods in California (Lucht & Kasper, 1999). There are many inconsistent studies in the United States that indicate whether there is a higher fluctuation in women’s moods during seasonal change than there is with men(Chotai, Smedh, Johansson, Nilsson, Adolfsson, 2003). The current study investigated gender differences in college students and how weather impacts their overall mood in Northern California. It was hypothesized that women have a higher Global Seasonality Score (GSS) than men. It was also hypothesized that college -aged women experience more seasonal fluctuations in mood, socialization, sleep, eating patterns, and weight gain than men do. The current study involved 60 college students from a northern California university. The Seasonal Pattern Assessment Questionnaire (SPAQ; Rosenthal, 1984), a 7-item survey that measures of winter pattern seasonality of mood in the general population along with demographic and weather related questions were used to assess the effects of weather on mood and behavioral patterns. Results are expected to conclude that there is a statistically significant difference in GSS between men and women. Analyses are also expected to indicate that women’s mood, socialization, sleep, eating patterns ...


Enhancing The Effectiveness Of Inpatient Palliative Care Consultation Teams (Pccts), Meghan McDarby 2018 Washington University in St. Louis

Enhancing The Effectiveness Of Inpatient Palliative Care Consultation Teams (Pccts), Meghan Mcdarby

Arts & Sciences Electronic Theses and Dissertations

Inpatient palliative care consultation teams (PCCTs) provide supportive care to individuals with chronic, life-limiting illness and their families. However, the clinical effectiveness of the PCCT may be affected by the quality of their collaboration with other providers. The purpose of this two-part study was to describe the efforts of inpatient PCCTs in order to (1) determine whether their expertise is maximized by other providers and (2) identify factors that may hinder or facilitate their successful collaboration with other providers. Descriptive analyses of retrospective chart review data (N = 120 charts) suggest that the majority of PCCT recommendations to other providers focus ...


Detecting Opioid-Related Aberrant Behavior Using Natural Language Processing, Jesse M. Lingeman, Priscilla Wang, William Becker, Hong Yu 2018 University of Massachusetts Amherst

Detecting Opioid-Related Aberrant Behavior Using Natural Language Processing, Jesse M. Lingeman, Priscilla Wang, William Becker, Hong Yu

Open Access Articles

The United States is in the midst of a prescription opioid epidemic, with the number of yearly opioid-related overdose deaths increasing almost fourfold since 2000(1). To more effectively prevent unintentional opioid overdoses, the medical profession requires robust surveillance tools that can effectively identify at-risk patients. Drug-related aberrant behaviors observed in the clinical context may be important indicators of patients at risk for or actively abusing opioids. In this paper, we describe a natural language processing (NLP) method for automatic surveillance of aberrant behavior in medical notes relying only on the text of the notes. This allows for a robust ...


The Predictors Of Juvenile Recidivism: Testimonies Of Adult Students 18 Years And Older Exiting From Alternative Education, La Toshia Palmer 2018 Brandman University

The Predictors Of Juvenile Recidivism: Testimonies Of Adult Students 18 Years And Older Exiting From Alternative Education, La Toshia Palmer

Dissertations

Purpose: The purpose of this descriptive, qualitative study was to identify and describe the importance of the predictors of juvenile recidivism and the effectiveness of efforts to prevent/avoid juvenile recidivism as perceived by previously detained, arrested, convicted, and/or incarcerated adult students 18 years of age and older exiting from alternative education in Northern California. A second purpose was to explore the types of support provided by alternative schools and the perceived importance of the support to avoid recidivism according to adult students 18 years of age and older exiting from alternative education.

Methodology: This qualitative, descriptive research design ...


Anxiety, Depression, And Adverse Clinical Outcomes In Patients With Atrial Fibrillation Starting Warfarin: Cardiovascular Research Network Wave Study, Christine Baumgartner, Dongjie Fan, Margaret C. Fang, Daniel E. Singer, Daniel M. Witt, John R. Schmelzer, Marc S. Williams, Jerry H. Gurwitz, Sue Hee Sung, Alan S. Go 2018 University of California, San Francisco

Anxiety, Depression, And Adverse Clinical Outcomes In Patients With Atrial Fibrillation Starting Warfarin: Cardiovascular Research Network Wave Study, Christine Baumgartner, Dongjie Fan, Margaret C. Fang, Daniel E. Singer, Daniel M. Witt, John R. Schmelzer, Marc S. Williams, Jerry H. Gurwitz, Sue Hee Sung, Alan S. Go

Open Access Articles

BACKGROUND: Anxiety and depression are associated with worse outcomes in several cardiovascular conditions, but it is unclear whether they affect outcomes in atrial fibrillation (AF). In a large diverse population of adults with AF, we evaluated the association of diagnosed anxiety and/or depression with stroke and bleeding outcomes.

METHODS AND RESULTS: The Cardiovascular Research Network WAVE (Community-Based Control and Persistence of Warfarin Therapy and Associated Rates and Predictors of Adverse Clinical Events in Atrial Fibrillation and Venous Thromboembolism) Study included adults with AF newly starting warfarin between 2004 and 2007 within 5 health delivery systems in the United States ...


Association Between Food Insecurity And Cvd Risk Factors Is Moderated By Intake Of Fruits And Vegetables In Latinos, Andrea Lopez-Cepero, Stephenie C. Lemon, Milagros C. Rosal 2018 University of Massachusetts Medical School

Association Between Food Insecurity And Cvd Risk Factors Is Moderated By Intake Of Fruits And Vegetables In Latinos, Andrea Lopez-Cepero, Stephenie C. Lemon, Milagros C. Rosal

UMass Worcester PRC Presentations

Background: Food insecurity has been consistently associated with CVD risk factors (i.e., obesity, type 2 diabetes, hypertension and hypercholesterolemia). Consumption of fruits and vegetables may reduce CVD risk factors among food insecure Latinos.

Objective: To examine the potential moderating effect of fruit and vegetable intake in the association between food insecurity and CVD risk factors in a sample of Latino men and women in the northeast U.S.

Methods: A representative community sample of Latino individuals was recruited from a community health center in Lawrence, MA. Food insecurity was measured with the 6-item USDA Household Food Security Scale. Fruit ...


A Model For Rigorously Applying The Exploration, Preparation, Implementation, Sustainment (Epis) Framework In The Design And Measurement Of A Large Scale Collaborative Multi-Site Study, Jennifer E. Becan, John P. Bartkowski, Danica K. Knight, Tisha R. A. Wiley, Ralph DiClemente, Lori Ducharme, Wayne N. Welsh, Diana Bowser, Kathryn McCollister, Matthew Hiller, Anne C. Spaulding, Patrick M. Flynn, Andrea Swartzendruber, Megan F. Dickson, Jacqueline Horan Fisher, Gregory A. Aarons 2018 Texas Christian University

A Model For Rigorously Applying The Exploration, Preparation, Implementation, Sustainment (Epis) Framework In The Design And Measurement Of A Large Scale Collaborative Multi-Site Study, Jennifer E. Becan, John P. Bartkowski, Danica K. Knight, Tisha R. A. Wiley, Ralph Diclemente, Lori Ducharme, Wayne N. Welsh, Diana Bowser, Kathryn Mccollister, Matthew Hiller, Anne C. Spaulding, Patrick M. Flynn, Andrea Swartzendruber, Megan F. Dickson, Jacqueline Horan Fisher, Gregory A. Aarons

Center on Drug and Alcohol Research Faculty Publications

Background

This paper describes the means by which a United States National Institute on Drug Abuse (NIDA)-funded cooperative, Juvenile Justice-Translational Research on Interventions for Adolescents in the Legal System (JJ-TRIALS), utilized an established implementation science framework in conducting a multi-site, multi-research center implementation intervention initiative. The initiative aimed to bolster the ability of juvenile justice agencies to address unmet client needs related to substance use while enhancing inter-organizational relationships between juvenile justice and local behavioral health partners.

Methods

The EPIS (Exploration, Preparation, Implementation, Sustainment) framework was selected and utilized as the guiding model from inception through project completion; including ...


Non-Hispanic Black-White Disparities In Pain And Pain Management Among Newly Admitted Nursing Home Residents With Cancer, Deborah Mack, Jacob N. Hunnicutt, William M. Jesdale, Kate L. Lapane 2018 University of Massachusetts Medical School

Non-Hispanic Black-White Disparities In Pain And Pain Management Among Newly Admitted Nursing Home Residents With Cancer, Deborah Mack, Jacob N. Hunnicutt, William M. Jesdale, Kate L. Lapane

UMass Center for Clinical and Translational Science Supported Publications

Background: Racial disparities in pain management persist across health care settings and likely extend into nursing homes. No recent studies have evaluated racial disparities in pain management among residents with cancer in nursing homes at time of admission.

Methods: Using a cross-sectional study design, we compared reported pain and pain management between non-Hispanic White and non-Hispanic Black newly admitted nursing home residents with cancer (n=342,920) using the de-identified Minimum Data Set version 3.0. Pain management strategies included the use of scheduled analgesics, pro re nata analgesics, and non-pharmacological methods. Presence of pain was based on self-report when ...


Film Screening: What Doesn't Kill Me, LeeAnn Bartolini 2018 Dominican University of California

Film Screening: What Doesn't Kill Me, Leeann Bartolini

Community Engagement Theme

No abstract provided.


Inhibition Of Tnf-Alpha Decreases Microglia Activation In Rats Neonatally Treated With Poly I:C, Heath W. Shelton, Russell W. Brown 2018 East Tennessee State University

Inhibition Of Tnf-Alpha Decreases Microglia Activation In Rats Neonatally Treated With Poly I:C, Heath W. Shelton, Russell W. Brown

Appalachian Student Research Forum

Introduction: Current medical treatment for individuals diagnosed with schizophrenia (SCHZ) primarily relies on the inhibition of the dopamine D2 receptor that has been shown to be supersensitive in these patients. Treatment occurs through the use of antipsychotic medication which leads to a number of debilitating dose-dependent side effects, such as weight gain, agranulocytosis, and seizures. Patients diagnosed with SCHZ have also been shown to have increased inflammation in their central nervous system (CNS), particularly within specific brain regions such as the prefrontal cortex and hippocampus. This is in large part due to the interaction between a pro-inflammatory cytokine called ...


Association Between Alzheimer's Disease And Rural Northeast Tennessee Region Between 2013 And 2015, Sylvester Olubolu Orimaye, Jodi Southerland 2018 East Tennessee State University

Association Between Alzheimer's Disease And Rural Northeast Tennessee Region Between 2013 And 2015, Sylvester Olubolu Orimaye, Jodi Southerland

Appalachian Student Research Forum

Background: Alzheimer’s disease (AD) is a type of Dementia and a neurodegenerative disease that is characterized by the gradual degrading of both memory and cognitive functions. According to the World Health Organization (WHO), the prevalence of AD is increasing globally. Currently, AD is the sixth leading cause of mortality in the United States. As the ageing population increases in the United States, it is possible that AD will move up the ladder in the top cause of mortality. Although the prevalence of AD in most urban parts of developed nations such as the United States is widely known, little ...


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