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Interview No. 1622, Michael Fushille M.D. 2010 University of Texas at El Paso

Interview No. 1622, Michael Fushille M.D.

Combined Interviews

He describes the process of getting into medical school, and trying to keep his G.I. benefits. Dr. Fushille enlisted in the Navy before the war and was accepted, but was told to remain in school because they had no place for him. He eventually served on an aircraft carrier during WWII, where he faced hurricanes, fires, and kamikaze attacks by the Japanese. Dr. Fushille served in the combat information center on the carrier as a radar technician. He finished his medical exams in 1957, before returning to New Jersey to complete his internship; by this time he and his ...


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Assessment Of Tissue Fibrosis In Skin Biopsies From Patients With Systemic Sclerosis Employing Confocal Laser Scanning Microscopy: An Objective Outcome Measure For Clinical Trials?, Joanna Busquets, Francesco Del Galdo, Eugene Y. Kissin, Sergio A. Jimenez 2010 Thomas Jefferson University

Assessment Of Tissue Fibrosis In Skin Biopsies From Patients With Systemic Sclerosis Employing Confocal Laser Scanning Microscopy: An Objective Outcome Measure For Clinical Trials?, Joanna Busquets, Francesco Del Galdo, Eugene Y. Kissin, Sergio A. Jimenez

Jefferson Institute of Molecular Medicine Papers and Presentations

OBJECTIVES: To obtain an objective, unbiased assessment of skin fibrosis in patients with SSc for use in clinical trials of SSc disease-modifying therapeutics.

METHODS: Skin biopsies from the dorsal forearm of six patients with diffuse SSc and six healthy controls, and skin biopsies from the forearm of one patient with diffuse SSc before and following 1 year treatment with mycophenolate mofetil were analysed by confocal laser scanning microscopy (CLSM) with specific antibodies against collagen types I and III or fibronectin. The integrated density of fluorescence (IDF) was calculated employing National Institutes of Health-ImageJ software in at least four different fields ...


Electronic Medical Records As A Research Tool: Evaluating Topiramate Use At A Headache Center., Michael J. Marmura, MD, Mary Hopkins, RN, MSN, Jocelyn Andrel, MSPH, William B. Young, MD, David M. Biondi, DO, Marcia F.T. Rupnow, PhD, Robert B. Armstrong, MD 2010 Thomas Jefferson University

Electronic Medical Records As A Research Tool: Evaluating Topiramate Use At A Headache Center., Michael J. Marmura, Md, Mary Hopkins, Rn, Msn, Jocelyn Andrel, Msph, William B. Young, Md, David M. Biondi, Do, Marcia F.T. Rupnow, Phd, Robert B. Armstrong, Md

Department of Neurology Faculty Papers

Background.—Electronic medical records (EMRs) are used in large healthcare centers to increase efficiency and accuracy of documentation. These databases may be utilized for clinical research or to describe clinical practices such as medication usage.

Methods.—We conducted a retrospective analysis of EMR data from a headache clinic to evaluate clinician prescription use and dosing patterns of topiramate. The study cohort comprised 4833 unique de-identified records, which were used to determine topiramate dose and persistence of treatment.

Results.—Within the cohort, migraine was the most common headache diagnosis (n = 3753, 77.7%), followed by tension-type headache (n = 338, 7.0 ...


Metabolic Syndrome In The American Hispanic Population: What Does The Evidence Show?, Sharon Strang 2010 James Madison University

Metabolic Syndrome In The American Hispanic Population: What Does The Evidence Show?, Sharon Strang

Sharon L. Strang

No abstract provided.


Test–Retest Reliability Of The Soleus H-Reflex Is Affected By Joint Positions And Muscle Force Levels, Yungsheng Chen, Shi Zhou, Colleen Cartwright, Zachary Crowley, Robert Baglin, Fang Wang 2010 Southern Cross University

Test–Retest Reliability Of The Soleus H-Reflex Is Affected By Joint Positions And Muscle Force Levels, Yungsheng Chen, Shi Zhou, Colleen Cartwright, Zachary Crowley, Robert Baglin, Fang Wang

Professor Colleen M Cartwright

The purpose of this study was to determine the test-retest reliability of the soleus (SOL) H-reflex during rest and isometric contractions at 10%, 30%, and 50% of the maximal voluntary force (MVC) at the ankle joint angles of neutral (0°), plantarflexion (20°), and dorsiflexion (-20°) respectively, in a sitting position. Ten healthy participants, with mean age of 24.9 ± 5.0 (SD) years, height 168.3 ± 8.8 cm, weight 62.7 ± 12.3 kg, were tested for the SOL H-reflex (Hmax) on two separate occasions within 7 days. The intra-class correlation coefficient (ICC) for the test–retest of the ...


Today - March 3, 2010, Loma Linda University 2010 Loma Linda University

Today - March 3, 2010, Loma Linda University

TODAY

Inside this issue:

-- Pediatric residency at SACHS-Norton clinic brings physicians face to face with the health care needs of inner city kids
-- Inland Empire boy helps Loma Linda University assist the children of Haiti
-- CHIP program coming to Loma Linda
-- Longtime LLU professor writes new book on whole person medicine
-- The China Study author to speak at Loma Linda University Church
-- Big Hearts for Little Hearts Loma Linda Guild hosts ‘Dressing Up Red’ Luncheon
-- Children’s Hospital to benefit from Food 4 Less fundraiser
-- ‘The Adventists’ documentary makes West Coast premiere in Loma Linda
-- SAHP announces 1,007 enrollment during ...


Unmasking The Moving Threat: Reckless Driving, Borderline Personality Disorder, And The Impact On Motor Vehicle Accidents, Charlene Lam 2010 Wright State University - Main Campus

Unmasking The Moving Threat: Reckless Driving, Borderline Personality Disorder, And The Impact On Motor Vehicle Accidents, Charlene Lam

Master of Public Health Program Student Publications

Background: Motor vehicle accidents (MVAs), a leading cause of mortality in the United States have an enormous impact on public health. Researchers contend that approximately 90% of all MVAs are, to some extent, a result of driver characteristics and behavior (Lewin, 1982). One of the least researched driver characteristics is psychiatric comorbidity, especially borderline personality disorder (BPD), a disorder that is characterized by impulsivity and emotional volatility.

Objective: The purpose of this study is to examine the relationship between BPD and driving citations.

Method: Using two measures for BPD, we surveyed a consecutive sample of patients who were being seen ...


Obat Gatal Area Selangkangan, obatgatal seluruhtubuh 2010 Bryant University

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The Narrative Exercise: Introduction To Therapeutic Communication In The Psychiatry Clerkship, David A. Garrison, Julia Frank 2010 University of Rochester

The Narrative Exercise: Introduction To Therapeutic Communication In The Psychiatry Clerkship, David A. Garrison, Julia Frank

E-Learning Modules

Introduction: In medical school, much time is devoted to teaching students to elicit disease-centered histories from their patients. The narrative exercise supplements this traditional focus by requiring students to develop a person-centered narrative for one patient under their care. While the ultimate test of a diagnosis is the verification of the diagnosis by tests or treatment outcome, the ultimate test of a patient-centered narrative is whether the patient accepts it as a legitimate characterization of his or her experience.

Methods: The psychiatry clerkship directors at the University of Rochester School of Medicine and George Washington University School of Medicine have ...


Symptom Recognition In Elders With Heart Failure, Barbara Riegel, Victoria V. Dickson, Janette Cameron, Jerry C. Johnson, Stephen Bunker, Karen Page, Linda Worrall-Carter 2010 University of Pennsylvania

Symptom Recognition In Elders With Heart Failure, Barbara Riegel, Victoria V. Dickson, Janette Cameron, Jerry C. Johnson, Stephen Bunker, Karen Page, Linda Worrall-Carter

School of Nursing Departmental Papers

Purpose: Aging is associated with losses in hearing and vision. The objective of this study was to assess whether aging also is associated with less ability to detect and interpret afferent physiological information.

Design: A cross‐sectional mixed methods study was conducted with 29 persons with a confirmed diagnosis of chronic heart failure of at least 6 months duration. The sample was divided at the median to compare younger (<73 years) versus older (≥73 years) patients in the ability to detect and interpret their heart failure symptoms.

Methods: Shortness of breath was stimulated using a 6‐minute walk test (6MWT) and used to assess the ability of heart failure patients to detect shortness of breath using the Borg ...


Identification Of Functional Modules That Correlate With Phenotypic Difference: The Influence Of Network Topology, Jui-Hung Hung, Troy W. Whitfield, Tun-Hsiang Yang, Zhenjun Hu, Zhiping Weng, Charles Delisi 2010 Boston University

Identification Of Functional Modules That Correlate With Phenotypic Difference: The Influence Of Network Topology, Jui-Hung Hung, Troy W. Whitfield, Tun-Hsiang Yang, Zhenjun Hu, Zhiping Weng, Charles Delisi

Open Access Publications by UMMS Authors

One of the important challenges to post-genomic biology is relating observed phenotypic alterations to the underlying collective alterations in genes. Current inferential methods, however, invariably omit large bodies of information on the relationships between genes. We present a method that takes account of such information - expressed in terms of the topology of a correlation network - and we apply the method in the context of current procedures for gene set enrichment analysis.


Behavioral Health Disorders And The Quality Of Diabetes Care: A Dissertation, Yat (Gary) Hung Leung 2010 University of Massachusetts Medical School

Behavioral Health Disorders And The Quality Of Diabetes Care: A Dissertation, Yat (Gary) Hung Leung

GSBS Dissertations and Theses

Both diabetes and behavioral health disorders (mental and substance use disorders) are significant health issues in the United States. While previous studies have shown worse health outcomes in people with diabetes and co-occurring behavioral health disorders (BHDs) than those with diabetes alone, it is unclear whether the quality of diabetes care was poorer in the presence of co-occurring BHDs. Although previous research has observed a trend of positive outcomes in people with comprehensive diabetes care, there is a lack of evidence about whether that mode of care delivery can improve outcomes in people with co-occurring BHDs. Therefore, further studies are ...


Countervailing Power In Wholesale Pharmaceuticals, Sara F. Ellison, Christopher M. Snyder 2010 Massachusetts Institute of Technology

Countervailing Power In Wholesale Pharmaceuticals, Sara F. Ellison, Christopher M. Snyder

Open Dartmouth: Published works by Dartmouth faculty

Using data on wholesale prices for antibiotics sold to U.S. drugstores, we test the growing theoretical literature on ‘countervailing power’ (a term for the ability of large buyers to extract discounts from suppliers). Large drugstores receive a modest discount for antibiotics produced by competing suppliers but no discount for antibiotics produced by monopolists. These findings support theories suggesting that supplier competition is a prerequisite for countervailing power. As further evidence for the importance of supplier competition, we find that hospitals receive substantial discounts relative to drugstores, attributed to hospitals' greater ability to induce supplier competition through restrictive formularies.


An Integral Role Of Arrdc3 In Stem Cell Migration And Breast Cancer Progression: A Dissertation, Kyle M. Draheim 2010 University of Massachusetts Medical School

An Integral Role Of Arrdc3 In Stem Cell Migration And Breast Cancer Progression: A Dissertation, Kyle M. Draheim

GSBS Dissertations and Theses

Despite the importance of integrins in epithelial cell biology surprisingly little is known about their regulation. It is known that they form hemidesmosomes (HDs), are actively involved in cell contacts during cell migration/invasion, and are key signaling molecules for survival and growth. However, there has been a distinct lack of understanding about what controls the dynamic integrin localization during cell activation and movement. Growth factors, such as EGF, are elevated during wound healing and carcinoma invasion leading to phosphorylation of ITGβ4 and the disassembly of the HD and mobilization of ITGβ4 to actin-rich protrusions. More recently the phosphorylation of ...


Findings From The Research On The Rural Pharmacy Workforce, Janie Smith 2010 Bond University

Findings From The Research On The Rural Pharmacy Workforce, Janie Smith

Janie Smith

No abstract provided.


Ion Selective Electrodes (Ises) And Interferences – A Review, Goce Dimeski, Tony Badrick, Andrew St John 2010 Bond University

Ion Selective Electrodes (Ises) And Interferences – A Review, Goce Dimeski, Tony Badrick, Andrew St John

Tony Badrick

Ion Selective Electrodes (ISEs) are used to measure some of the most critical analytes on clinical laboratory and point-of-care analysers. These analytes which include Na(+), K(+), Cl(-), Ca(2+), Mg(2+) and Li(+) are used for rapid patient care decisions. Although the electrodes are very selective, they are not free of interferences. It is important for laboratories to have an understanding of the type and extent of interferences in order to avoid incorrect clinical decisions and treatment.


Changing Po2licy: The Elements For Improving Childhood Asthma Outcomes, Anne Rossier Markus, Meagan Lyon, Sara J. Rosenbaum 2010 George Washington University

Changing Po2licy: The Elements For Improving Childhood Asthma Outcomes, Anne Rossier Markus, Meagan Lyon, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Childhood asthma is a serious and chronic health issue that affects one in seven U.S. children and their families, compromising their health and quality of life and placing a heavy financial burden on families as well as an enormous strain on the health care system. Treating, managing, and ultimately preventing and reducing the burden of asthma represents a critical test of the ability of the U.S. health system – health insurers, clinical care providers, and public health agencies – to work together. Our investigation found that, as a country, we already know enough to act and improve life for the ...


The Effect Of Medicare Part D On Pharmaceutical Prices And Utilization, Mark Duggan, Fiona S. morton 2010 University of Pennsylvania

The Effect Of Medicare Part D On Pharmaceutical Prices And Utilization, Mark Duggan, Fiona S. Morton

Health Care Management Papers

Medicare Part D began coverage of prescription drugs in 2006. Rather than setting pharmaceutical prices, the government contracted with private insurers to provide drug coverage. Theory suggests that additional insured consumers will raise the optimal price of a branded drug, while the insurer's ability to move demand to substitute treatments may lower prices. We estimate the program's effect on the price and utilization of pharmaceutical treatments. We find that Part D enrollees paid substantially lower prices than while uninsured, and increased their utilization of prescription drugs. We find relative price declines only for drugs with significant therapeutic competition.


Comparison Of Nine Different Real-Time Pcr Chemistries For Qualitative And Quantitative Applications In Gmo Detection, Torstein Tengs 2010 Norwegian Veterinary Institute

Comparison Of Nine Different Real-Time Pcr Chemistries For Qualitative And Quantitative Applications In Gmo Detection, Torstein Tengs

Dr. Torstein Tengs

Several techniques have been developed for detection and quantification of genetically modified organisms, but quantitative real-time PCR is by far the most popular approach. Among the most commonly used realtime PCR chemistries are TaqMan probes and SYBR green, but many other detection chemistries have also been developed. Because their performance has never been compared systematically, here we present an extensive evaluation of some promising chemistries: sequenceunspecific DNA labeling dyes (SYBR green), primer-based technologies (AmpliFluor, Plexor, Lux primers), and techniques involving double-labeled probes, comprising hybridization (molecular beacon) and hydrolysis (TaqMan, CPT, LNA, and MGB) probes, based on recently published experimental data ...


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