Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

203,686 Full-Text Articles 340,712 Authors 45,816,135 Downloads 465 Institutions

All Articles in Medicine and Health Sciences

Faceted Search

203,686 full-text articles. Page 7615 of 7627.

Persistent Suicide Risk In Clinically Improved Schizophrenia Patients: Challenge Of The Suicidal Dimension, Amresh Shrivastava, Megan Johnston, Nilesh Shah, Marco Innamorati, Larry Stitt, Meghana Thakar, David Lester, Maurizio Pompili 2009 The University of Western Ontario

Persistent Suicide Risk In Clinically Improved Schizophrenia Patients: Challenge Of The Suicidal Dimension, Amresh Shrivastava, Megan Johnston, Nilesh Shah, Marco Innamorati, Larry Stitt, Meghana Thakar, David Lester, Maurizio Pompili

Amresh Srivastava

BACKGROUND: Suicide is a major problem in schizophrenia, estimated to affect 9%-13% of patients. About 25% of schizophrenic patients make at least one suicide attempt in their lifetime. Current outcome measures do not address this problem, even though it affects quality of life and patient safety. The aim of this study was to assess suicidality in long-term clinically improved schizophrenia patients who were treated in a nongovernmental psychiatric treatment centre in Mumbai, India.

METHOD: Participants were 61 patients out of 200 consecutive hospitalized first-episode patients with schizophrenia diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders who ...


Esophageal Dysfunction In Four Alpaca Crias And A Llama Cria With Vascular Ring Anomalies., E. McKenzie, B. Sequin, C. Cebra, M. Margiocco, David Anderson, C. Löhr 2009 Kansas State University

Esophageal Dysfunction In Four Alpaca Crias And A Llama Cria With Vascular Ring Anomalies., E. Mckenzie, B. Sequin, C. Cebra, M. Margiocco, David Anderson, C. Löhr

David Edgar Anderson, DVM, MS, DACVS

CASE DESCRIPTION: 3 alpaca crias and cadavers of an alpaca cria and a llama cria were evaluated for evidence of esophageal dysfunction. CLINICAL FINDINGS: All 5 crias were between 3 and 5 months of age when clinical signs developed, and all had a thin body condition when examined. Clinical signs included coughing, regurgitation, and grossly visible esophageal peristaltic waves. A barium esophagram was used to diagnose esophageal obstruction, megaesophagus, and a vascular ring anomaly (VRA). Fluoroscopy was used to evaluate deglutition, esophageal peristalsis, and the extent of esophageal dilation in 1 alpaca cria. A persistent right aortic arch was identified ...


Haematopoietic Stem Cells In Spleen Have Distinct Differentiative Potential For Antigen Presenting Cells., Jonathan Tan, Helen O'Neill 2009 Australian National University

Haematopoietic Stem Cells In Spleen Have Distinct Differentiative Potential For Antigen Presenting Cells., Jonathan Tan, Helen O'Neill

Helen O'Neill

Dendritic cells (DC) are known to develop from macrophage dendritic progenitors (MDP) in bone marrow (BM), which give rise to conventional (c)DC and monocytes, both dominant antigen presenting cell (APC) subsets in spleen. This laboratory has however defined a distinct dendritic-like cell subset in spleen (L-DC), which can also be derived in long-term cultures of spleen. In line with the restricted in vitro development of only L-DC in these stromal cultures, we questioned whether self-renewing HSC or progenitors exist in spleen with restricted differentiative capacity for only L-DC. Neonatal spleen and BM were compared for their ability to reconstitute ...


Effects Of Domperidone On Digital Laminar Microvascular Blood Flow In Clinically Normal Adult Horses, Jose Castro, Henry Adair, III, SV Radecki, VR Kiefer, SB Elliot, SL Longhofer 2009 University of Tennessee - Knoxville

Effects Of Domperidone On Digital Laminar Microvascular Blood Flow In Clinically Normal Adult Horses, Jose Castro, Henry Adair, Iii, Sv Radecki, Vr Kiefer, Sb Elliot, Sl Longhofer

Henry S. Adair, III MS, DVM, DACVS

OBJECTIVE: To determine effects of domperidone and acepromazine maleate on microvascular blood flow in digital laminae of clinically normal adult horses. ANIMALS: 8 clinically normal adult horses (4 mares and 4 geldings). PROCEDURES: In a 4-period crossover study, domperidone was administered PO at 1.1 mg/ kg and 5.5 mg/kg and IV at 0.2 mg/kg; acepromazine was administered IV at 0.04 mg/kg. The washout period between treatments was 1 week. A 3-minute measurement of laminar microvascular blood flow (LMBF) was obtained with laser Doppler flowmetry. Baseline measurements were obtained at -2, -1, and 0 ...


Gingival Osteogenic Melanoma In Two Dogs., A. Ellis, B. Harmon, Debra Miller, N. Northup, K. Latimer, E. Uhl 2009 University of Tennessee, Knoxville

Gingival Osteogenic Melanoma In Two Dogs., A. Ellis, B. Harmon, Debra Miller, N. Northup, K. Latimer, E. Uhl

Debra L Miller

Osteogenic melanoma is a rare variant of metaplastic malignant melanoma in human medicine and appears to be a similarly rare variant in dogs. Two dogs with oral malignant melanoma with neoplastic bone formation are reported in this study. Both tumors were characterized by malignant melanocytes that transitioned into neoplastic bone at the deep margins of the neoplasm. Immunohistochemical analysis revealed S100- and Melan-A-positive neoplastic cells adjacent to, and occasionally embedded within, an osteoid and chondroblastic matrix. Scattered clusters of neoplastic cells were also positive for osteocalcin. The findings indicate that in dogs, as in humans, neoplastic melanocytes have metaplastic potential ...


A Journey With A Clear Destination: Environmental Health Research, R. Konkel, David Evans, M. Mulcahy 2009 Eastern Kentucky University

A Journey With A Clear Destination: Environmental Health Research, R. Konkel, David Evans, M. Mulcahy

Steve Konkel

Research is vital if we are to improve the health of the population on the island of Ireland and provide better qualtiy and access to services. Yet all too often, research can be a neglected and overlooked component of evironmental health.


Lysophosphatidic Acid Induction Of Interleukin 6 Secretion From Aortic Smooth Muscle Cells Via Lpa1 Regulated, Pkc Dependent And P38alpha Mediated Pathway, F. Hao, M. Tan, D. Wu, X. Xu, Mei Cui 2009 University of Tennessee, Knoxville

Lysophosphatidic Acid Induction Of Interleukin 6 Secretion From Aortic Smooth Muscle Cells Via Lpa1 Regulated, Pkc Dependent And P38alpha Mediated Pathway, F. Hao, M. Tan, D. Wu, X. Xu, Mei Cui

Mei-Zhen Cui

Lysophosphatidic acid (LPA) is a potent bioactive lysophospholipid. Accumulated evidence supports a role for LPA in inflammation. To profile LPA-induced cytokine production in vascular smooth muscle cells (SMCs), we used a cytokine antibody array system and found that LPA prominently induces the secretion of IL-6 and monocyte chemoattractant protein (MCP)-1 from human aortic SMCs (HASMCs). The mechanism by which LPA induces MCP-1 expression in SMCs has been previously reported. However, LPA induction of IL-6 secretion from vascular SMCs and its regulatory mechanism are unknown. The present study reveals that LPA induces the expression of IL-6 mRNA and protein in ...


Slug (Snai2) Expression During Skin And Hair Follicle Development. Parent A, Newkirk K, Kusewitt D, Kim Newkirk 2009 University of Tennessee - Knoxville

Slug (Snai2) Expression During Skin And Hair Follicle Development. Parent A, Newkirk K, Kusewitt D, Kim Newkirk

Kim M Newkirk

No abstract provided.


What Is Your Diagnosis? Congenital Portosystemic Shunt In A Dog, M Anderson, Silke Hecht, Amy Holford, David Hicks 2009 University of Tennessee - Knoxville

What Is Your Diagnosis? Congenital Portosystemic Shunt In A Dog, M Anderson, Silke Hecht, Amy Holford, David Hicks

Silke Hecht

No abstract provided.


Premedication With Topical 1% Prednisolone Acetate In Dogs Undergoing Phacoemulsification: Effects Of One Week Vs. One Day Preoperative Regimens, NJ McLean, Daniel Ward, Diane Hendrix 2009 University of Tennessee, Knoxville

Premedication With Topical 1% Prednisolone Acetate In Dogs Undergoing Phacoemulsification: Effects Of One Week Vs. One Day Preoperative Regimens, Nj Mclean, Daniel Ward, Diane Hendrix

Daniel A. Ward

No abstract provided.


Nsaid-Activated Gene-1 As A Molecular Target For Capsaicin-Induced Apoptosis Through A Novel Molecular Mechanism Involving Gsk3beta, C/Ebpbeta And Atf3, Seung Baek, Seong-Ho Lee, Chutwadee Krisanapun 2009 The University of Tennessee

Nsaid-Activated Gene-1 As A Molecular Target For Capsaicin-Induced Apoptosis Through A Novel Molecular Mechanism Involving Gsk3beta, C/Ebpbeta And Atf3, Seung Baek, Seong-Ho Lee, Chutwadee Krisanapun

Seung J Baek

Capsaicin, a natural product of the Capsicum species of red peppers, is known to induce apoptosis and suppress growth. Non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) is a cytokine associated with pro-apoptotic and antitumorigenic property in colorectal and lung cancer. Our data demonstrate that capsaicin leads to induction of apoptosis and up-regulates NAG-1 gene expression at the transcriptional level. Overexpression of CCAAT/enhancer binding protein beta (C/EBPbeta) caused a significant increase of basal and capsaicin-induced NAG-1 promoter activity. We subsequently identified C/EBPbeta binding sites in the NAG-1 promoter responsible for capsaicin-induced NAG-1 transactivation. Electrophoretic mobility shift assay and chromatin immunoprecipitation ...


Tailoring A Diabetes Nursing Elective Course To Millennial Students, Sharon Strang, M. Bagnardi, S. Utz 2009 James Madison University

Tailoring A Diabetes Nursing Elective Course To Millennial Students, Sharon Strang, M. Bagnardi, S. Utz

Sharon L. Strang

No abstract provided.


Return To Play After An Initial Or Recurrent Concussion In A Prospective Study Of Physician-Observed Junior Ice Hockey Concussions: Implications For Return To Play After A Concussion, Paul Echlin, Charles Tator, Michael Cusimano, Robert Cantu, Jack Taunton, Ross Upshur, Michael Czarnota, Craig Hall, Andrew Johnson, Lorie Forwell, Molly Driediger, Elaine Skopelja 2009 University of Toronto

Return To Play After An Initial Or Recurrent Concussion In A Prospective Study Of Physician-Observed Junior Ice Hockey Concussions: Implications For Return To Play After A Concussion, Paul Echlin, Charles Tator, Michael Cusimano, Robert Cantu, Jack Taunton, Ross Upshur, Michael Czarnota, Craig Hall, Andrew Johnson, Lorie Forwell, Molly Driediger, Elaine Skopelja

Andrew M. Johnson

Object. The authors investigated return-to-play duration for initial and recurrent concussion in the same season in 2 teams of junior (16–21-year-old) ice hockey players during a regular season. Methods. The authors conducted a prospective cohort study during 1 junior regular season (2009–2010) of 67 male fourth- tier ice hockey players (mean age


Multimodal Management Of Canine Osteoarthritis, Steven Fox, Darryl Millis 2009 University of Tennessee, Knoxville

Multimodal Management Of Canine Osteoarthritis, Steven Fox, Darryl Millis

Darryl L. Millis

No abstract provided.


Closing The Medical Buffet, Katrina Bramstedt 2009 Bond University

Closing The Medical Buffet, Katrina Bramstedt

Katrina A. Bramstedt

Extract:The standard hotel breakfast buffet includes trays of eggs Benedict, bacon, oatmeal, sliced fruit, muffins and bagels. Now imagine another type of buffet: the medical buffet. Instead of food, imagine a long table with segmented areas containing dialysis machines, ventilators, feeding tubes, organs for transplant, ventricular assist devices, blood for transfusion, transcutaneous electrotherapy devices, and spinal cord stimulation implants. Patients and families sometimes feel that the mere existence of a bounty of medical technology equates to their right to use it, even if the technology will offer no benefit. Skillful language from clinicians is needed in order that a ...


What Is Your Diagnosis? Congenital Portosystemic Shunt In A Dog, M Anderson, Silke Hecht, Amy Holford, David Hicks 2009 University of Tennessee - Knoxville

What Is Your Diagnosis? Congenital Portosystemic Shunt In A Dog, M Anderson, Silke Hecht, Amy Holford, David Hicks

Amy L. Holford VMD, DACVIM

No abstract provided.


Improving Risk Assessment With Suicidal Patients: A Preliminary Evaluation Of The Clinical Utility Of The Scale For Impact Of Suicidality - Management, Assessment And Planning Of Care (Sis-Map), Charles Nelson, Megan Johnston, Amresh Srivastava 2009 The University of Western Ontario

Improving Risk Assessment With Suicidal Patients: A Preliminary Evaluation Of The Clinical Utility Of The Scale For Impact Of Suicidality - Management, Assessment And Planning Of Care (Sis-Map), Charles Nelson, Megan Johnston, Amresh Srivastava

Amresh Srivastava

Although a number of suicide risk assessment tools are available to clinicians, the high levels of suicide still evident in society suggest a clear need for new strategies in order to facilitate the prevention of suicidal behaviors. The present study examined the utilization of a new structured clinical interview called the Scale for Impact of Suicidality Management, Assessment and Planning of Care (SIS-MAP). SIS-MAP ratings were obtained from a group of incoming psychiatric patients over a 6-month period at Regional Mental Health Care, St. Thomas, Ontario. A canonical discriminant function analysis resulted in a total 74.0% of original grouped ...


Effects Of Duration Of Untreated Psychosis On Long-Term Outcome Of ‘People Hospitalized With First Episode Schizophrenia”, Amresh Srivastava, Larry Stitt, Meghana Thakar, Gurusamy Chinnasamy, Nilesh Shah 2009 University of Western Ontario

Effects Of Duration Of Untreated Psychosis On Long-Term Outcome Of ‘People Hospitalized With First Episode Schizophrenia”, Amresh Srivastava, Larry Stitt, Meghana Thakar, Gurusamy Chinnasamy, Nilesh Shah

Amresh Srivastava

AIM: Duration of untreated psychosis (DUP), which has emerged as a reliable predictor of outcome continues to remain under scientific scrutiny . The present study examines effect of differential periods of DUP on long-term outcome of first episode schizophrenia at Mumbai, India. Method: This is a prospective, ten year follow up naturalistic study. Hospitalized patients of first episode schizophrenia were selected and followed up Results: The mean DUP was higher for group, which showed clinical recovery on Clinical Global Impression Scale [14.0 months (SD=8.0) in recovered and 10.8 months (SD=5.7) in non-recovered group (p=0 ...


Conducting A Needs Assessment For A Nurse-Managed Multidisciplinary Clinic, Sharon Strang, D. Glick, L. Hulton 2009 James Madison University

Conducting A Needs Assessment For A Nurse-Managed Multidisciplinary Clinic, Sharon Strang, D. Glick, L. Hulton

Sharon L. Strang

No abstract provided.


Measuring Parental Barriers To Childhood Immunizations: The Development And Validation Of The Searching For Hardships And Obstacles To Shots (Shots) Instrument, Victoria Niederhauser 2009 University of Tennessee, Knoxville

Measuring Parental Barriers To Childhood Immunizations: The Development And Validation Of The Searching For Hardships And Obstacles To Shots (Shots) Instrument, Victoria Niederhauser

Victoria Niederhauser

There is a plethora of literature on barriers to immunizations; however, these studies lack standardization of measurement. The aim of this study was to develop and establish an initial psychometric evaluation of an instrument to measure parental barriers to childhood immunizations. This was a cross-sectional study design. Data analysis included descriptive statistics, reliability estimates, item analysis, and factor analysis. Six hundred and fifty-five participants completed the survey. The Searching for Hardships and Obstacles to Shots instrument was developed with 60 items and reduced to 23 items thorough multiple statistical computations; the best factor model was a three-factor solution (Access to ...


Digital Commons powered by bepress