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The Quantification Of Tooth Displacement, Thomas W. Radmer, L Thomas Johnson, Mingan Yang, Thomas Wirtz 2010 Marquette University

The Quantification Of Tooth Displacement, Thomas W. Radmer, L Thomas Johnson, Mingan Yang, Thomas Wirtz

School of Dentistry Faculty Research and Publications

By using reference points from a single pixel marker placed at the center point of the cuspid teeth and the center point on each of the incisor teeth, a polynomial curve was generated as a native curve for each dental arch studied. The polynomial curve generated from actual tooth position in each arch provides the forensic odontologist with another reference point that is quantifiable. The study represents that individual characteristics, such as tooth displacement, can be quantified in a simple, reliable, and repeatable format.


Athlete And Coach Knowledge, Attitudes, And Perceptions Of Sickle Cell Trait And National Collegiate Athletic Association Mandated Testing: Recommendations For Intervention, Raymona Holloway Lawrence 2010 Georgia Southern University

Athlete And Coach Knowledge, Attitudes, And Perceptions Of Sickle Cell Trait And National Collegiate Athletic Association Mandated Testing: Recommendations For Intervention, Raymona Holloway Lawrence

Electronic Theses and Dissertations

Individuals with Sickle Cell Trait have died suddenly after extreme exertion during military training, athletic practice or games (Kerle & Nishimura, 1996; Harrelson, Fincher & Robinson, 1995; Howe & Bowden, 2007). One of those deaths, Dale Lloyd, a football player at Rice University, prompted a change in the National Collegiate Athletic Association's (NCAA) Sports Medicine Handbook Guideline 3c: The Student Athlete with Sickle Cell Trait. Effective August 2010, the NCAA Division I Proposal No. 2009-75-B mandated sickle cell trait testing in all Division I athletes unless documented results of a prior test are provided to the institution or the student-athlete declines the test and signs a written release. It is well-documented that in the United States, Sickle Cell Disease/Sickle Cell Trait primarily affects African Americans more than any other race or ethnicity (NIH, 2008). Sickle cell screening programs have been scrutinized since the 1970s (Pemberton & Wailoo, 2006) because of insensitivity to race. The recent change in NCAA Guideline 3c has been scrutinized partially for the same reason. The purpose of this mixed methods study was threefold. It was necessary to 1) determine perceptions of SCT and NCAA mandated SCT testing from college coaches and athletes' points of view; 2) determine the necessary components of the Sickle Cell Orientation and Education (S.C.OR.E) intervention that will be developed to educate intercollegiate athletes, as well as their coaches, about sickle cell trait from pre-participation screening to sickle cell trait diagnosis, and 3) to highlight the potential implications of an NCAA policy that mandates SCT testing. The PRECEDE-PROCEED (PRE-PRO) model of program planning was utilized to determine the necessary components of the intervention (Green & Kreuter, 1999). Constructs ...


Understanding Environmental Health Disparities Of Roma Populations In Romania, Jennifer L. Hall 2010 University of Northern Iowa

Understanding Environmental Health Disparities Of Roma Populations In Romania, Jennifer L. Hall

Dissertations and Theses @ UNI

The Roma are the largest and most marginalized minority group of Central and Eastern Europe (CEE) with the highest number residing in Romania. Their problems and struggles are multi-faceted and deeply rooted in a long history of discrimination and stigmatization. Over the years, many strategies have been developed and implemented across CEE, yet very few studies have addressed their environmental and occupational health issues. Moreover, because the vast majority of these studies have employed quantitative methodology, they have had the unfortunate effect of dehumanizing and devaluing the Roma people through scientific reductionism.

The purpose of this study was to gain ...


Trends Of Professionalization Of Nursing Faculty From 1993-2004, Wendy Wen-Chun Lin-Cook 2010 Seton Hall Univerisity

Trends Of Professionalization Of Nursing Faculty From 1993-2004, Wendy Wen-Chun Lin-Cook

Seton Hall University Dissertations and Theses (ETDs)

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Impaired M3 And Enhanced M2 Muscarinic Receptor Contractile Function In A Streptozotocin Model Of Mouse Diabetic Urinary Bladder, K. J. Pak, Rennolds S. Ostrom, M. Matsui, F. J. Ehlert 2010 University of California, Irvine

Impaired M3 And Enhanced M2 Muscarinic Receptor Contractile Function In A Streptozotocin Model Of Mouse Diabetic Urinary Bladder, K. J. Pak, Rennolds S. Ostrom, M. Matsui, F. J. Ehlert

Pharmacy Faculty Articles and Research

We investigated the contractile roles of M2 and M3 muscarinic receptors in urinary bladder from streptozotocin-treated mice. Wild-type and M2 muscarinic receptor knockout (M2 KO) mice were given a single injection of vehicle or streptozotocin (125 mg kg−1) 2–24 weeks prior to bladder assays. The effect of forskolin on contractions elicited to the muscarinic agonist, oxotremorine-M, was measured in isolated urinary bladder (intact or denuded of urothelium). Denuded urinary bladder from vehicle-treated wild-type and M2 KO mice exhibited similar contractile responses to oxotremorine-M, when contraction was normalized relative to that elicited by KCl (50 mM). Eight to 9 ...


The Able Scale: The Development And Psychometric Properties Of A New Outcome Measure For The Spinal Cord Injury Population, Elizabeth Ardolino 2010 Seton Hall University

The Able Scale: The Development And Psychometric Properties Of A New Outcome Measure For The Spinal Cord Injury Population, Elizabeth Ardolino

Seton Hall University Dissertations and Theses (ETDs)

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Analysis Of An Actin Binding Guanine Exchange Factor, Gef8, And Actin Depolymerizing Factor In Arabidopsis Thaliana., Aleksey Chudnovskiy 2010 University of Massachusetts Amherst

Analysis Of An Actin Binding Guanine Exchange Factor, Gef8, And Actin Depolymerizing Factor In Arabidopsis Thaliana., Aleksey Chudnovskiy

Masters Theses 1911 - February 2014

ABSTRACT ANALYSIS OF AN ACTIN BINDING GUANINE EXCHANGE FACTOR, GEF8, AND ACTIN DEPOLYMERIZING FACTOR IN ARABIDOPSIS THALIANA. April, 2010 Aleksey Chudnovskiy, B.S., UNIVERSITY OF MASSACHUSETTS AMHERST M.S., UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Alice Y. Cheung Polarized cell growth is a fundamental biological process that is tightly regulated spatially and temporally. In plants the key systems to study polar cell growth are pollen tubes and root hairs. In recent years a lot of work has focused on elucidating the mechanisms that mediate this process. The actin cytoskeleton plays a key role in polarized cell growth. Different studies ...


Role Of Transforming Growth Factor Beta In Corneal Function, Biology And Pathology, Ashish Tandon, Jonathan C. K. Tovey, Ajay Sharma, Rangan Gupta, Rajiv R. Mohan 2010 Harry S. Truman Memorial Veterans’ Hospital

Role Of Transforming Growth Factor Beta In Corneal Function, Biology And Pathology, Ashish Tandon, Jonathan C. K. Tovey, Ajay Sharma, Rangan Gupta, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Transforming growth factor-beta (TGFβ) is a pleiotropic multifunctional cytokine that regulates several essential cellular processes in many parts of the body including the cornea. Three isoforms of TGFβ are known in mammals and the human cornea expresses all of them. TGFβ1 has been shown to play a central role in scar formation in adult corneas whereas TGFβ2 and TGFβ3 have been implicated to play a critical role in corneal development and scarless wound healing during embryogenesis. The biological effects of TGFβ in the cornea have been shown to follow SMAD dependent as well as SMAD-independent signaling pathways depending upon cellular ...


Efficacy And Safety Of Mitomycin C As An Agent To Treat Corneal Scarring In Horses Using An In Vitro Model, Dylan G. Buss, Ajay Sharma, Elizabeth A. Giuliano, Rajiv R. Mohan 2010 Harry S. Truman Memorial Veterans' Hospital

Efficacy And Safety Of Mitomycin C As An Agent To Treat Corneal Scarring In Horses Using An In Vitro Model, Dylan G. Buss, Ajay Sharma, Elizabeth A. Giuliano, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective—Mitomycin C (MMC) is used clinically to treat corneal scarring in human patients. We investigated the safety and efficacy of MMC to treat corneal scarring in horses by examining its effects at the early and late stages of disease using an in-vitro model.

Procedure—An in-vitro model of equine corneal fibroblast (ECF) developed was used. The equine corneal fibroblast or myofibroblast cultures were produced by growing primary ECF in the presence or absence of transforming growth factor beta-1 (TGFβ1) under serum-free conditions. The MMC dose for the equine cornea was defined with dose-dependent trypan blue exclusion and MTT [(3-4 ...


Isolation And Cultivation Of Equine Corneal Keratocytes, Fibroblasts And Myofibroblasts, Dylan G. Buss, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan 2010 University of Missouri, Columbia

Isolation And Cultivation Of Equine Corneal Keratocytes, Fibroblasts And Myofibroblasts, Dylan G. Buss, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective—To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was developed.

Animal material—Equine corneal buttons were aseptically harvested from healthy research horses undergoing humane euthanasia for reasons unrelated to this study. Slit-lamp biomicroscopy was performed prior to euthanasia by a board-certified veterinary ophthalmologist to ensure that all samples were harvested from horses free of anterior segment disease.

Procedure—Equine corneal stroma was isolated using mechanical techniques and stromal subsections were then cultured. Customized media at different culture ...


"Transduction Efficiency Of Aav 2/6, 2/8 And 2/9 Vectors For Delivering Genes In Human Corneal Fibroblasts ", Ajay Sharma, Arkasubhra Ghosh, Eric T. Hansen, Jason M. Newman, Rajiv R. Mohan 2010 Chapman University

"Transduction Efficiency Of Aav 2/6, 2/8 And 2/9 Vectors For Delivering Genes In Human Corneal Fibroblasts ", Ajay Sharma, Arkasubhra Ghosh, Eric T. Hansen, Jason M. Newman, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

In the present study, cellular tropism and relative transduction efficiency of AAV2/6, AAV2/8 and AAV2/9 vectors have been tested for the cornea using primary cultures of human corneal fibroblasts. The AAV6, AAV8 and AAV9 serotypes having AAV2 ITR plasmid encoding for alkaline phosphatase (AP) gene were generated by transfecting HEK293 cell line with pHelper, pARAP4 and pRep/Cap plasmids. Primary cultures of human corneal fibroblasts were exposed to AAV infectious particles at two different doses (1×105 and 2×105 MOI). Cytochemistry and enzyme assays were used to measure delivered transgene expression in samples collected at 4 ...


Aav Serotype Influences Gene Transfer In Corneal Stroma In Vivo, Ajay Sharma, Jonathan C. K. Tovey, Arkasubhra Ghosh, Rajiv R. Mohan 2010 Chapman University

Aav Serotype Influences Gene Transfer In Corneal Stroma In Vivo, Ajay Sharma, Jonathan C. K. Tovey, Arkasubhra Ghosh, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

This study evaluated the cellular tropism and relative transduction efficiency of three AAV serotypes, AAV6, AAV8 and AAV9, for corneal gene delivery using mouse cornea in vivo and donor human cornea ex vivo. The AAV6, AAV8 and AAV9 serotypes having AAV2 plasmid encoding for alkaline phosphatase (AP) gene were generated by transfecting HEK293 cell line with pHelper, pARAP4 and pRep/Cap plasmids. Viral vectors (109 vg/μl) were topically applied onto mouse cornea in vivo and human cornea ex vivo after removing the epithelium. Human corneas were processed for transgene delivery at day 5 after viral vector application. Mouse corneas ...


Identification Of Parelaphostrongylus Odocoilei (Nematoda: Protostrongylidae) First-Stage Larvae In The Feces Of Gray Wolves (Canis Lupus) By Molecular Methods, Heather M. Bryan, Kathrin A. Sim, Chris T. Darimont, Paul C. Paquet, Brent Wagner, Violeta Muñoz-Fuentes, Judit E. Smits, Nell B. Chilton 2010 University of Saskatchewan

Identification Of Parelaphostrongylus Odocoilei (Nematoda: Protostrongylidae) First-Stage Larvae In The Feces Of Gray Wolves (Canis Lupus) By Molecular Methods, Heather M. Bryan, Kathrin A. Sim, Chris T. Darimont, Paul C. Paquet, Brent Wagner, Violeta Muñoz-Fuentes, Judit E. Smits, Nell B. Chilton

Parasitology Collection

First-stage nematode larvae with a dorsal-spine (DSL) were detected in five of 1,565 fecal samples from gray wolves (Canis lupus) collected in British Columbia, Canada, between 2005 and 2008. Molecular techniques were used to identify the DSL because it was not possible to determine their species identity using morphologic characters. The DSL were identified as Parelaphostrongylus odocoilei based on the results of single-strand conformation polymorphism (SSCP) analyses and DNA sequencing of the ribosomal DNA first and second internal transcribed spacers. Finding DSL of P. odocoilei in the feces of gray wolves was unexpected because P. odocoilei adults are parasites ...


The Reflect Statement: Reporting Guidelines For Randomized Controlled Trials In Livestock And Food Safety: Explanation And Elaboration, Jan M. Sargeant, Annette M. O'Connor, Ian A. Gardner, James S. Dickson, Mary E. Torrence, Ian R. Dohoo, Sandra L. Lefebvre, Paul S. Morley, Alejandro Ramirez, Kate Snedeker 2010 University of Guelph

The Reflect Statement: Reporting Guidelines For Randomized Controlled Trials In Livestock And Food Safety: Explanation And Elaboration, Jan M. Sargeant, Annette M. O'Connor, Ian A. Gardner, James S. Dickson, Mary E. Torrence, Ian R. Dohoo, Sandra L. Lefebvre, Paul S. Morley, Alejandro Ramirez, Kate Snedeker

Veterinary Diagnostic and Production Animal Medicine Publications

Concerns about the completeness and accuracy of reporting of randomized clinical trials (RCTs) and the impact of poor reporting on decision-making have been documented in the medical field over the past several decades. Experience from RCTs in human medicine would suggest that failure to report critical trial features can be associated with biased estimated effect measures, and there is evidence to suggest similar biases occur in RCTs conducted in livestock populations. In response to these concerns, standardized guidelines for reporting RCTs were developed and implemented in human medicine. The Consolidated Standards of Reporting Trials (CONSORT) statement was first published in ...


The Reflect Statement: Methods And Processes Of Creating Reporting Guidelines For Randomized Controlled Trials For Livestock And Food Safety, Annette M. O'Connor, Jan M. Sargeant, Ian A. Gardner, James S. Dickson, Mary E. Torrence, Cate E. Dewey, Ian R. Dohoo, Richard B. Evans, Jeffrey T. Gray, Mattias Greiner, Greg Keefe, Sandra L. Lefebvre, Paul S. Morley, Alejandro Ramirez, William Sischo, David R. Smith, Kate Snedeker, John N. Sofos, Michael P. Ward, Robert W. Wills 2010 University of Guelph

The Reflect Statement: Methods And Processes Of Creating Reporting Guidelines For Randomized Controlled Trials For Livestock And Food Safety, Annette M. O'Connor, Jan M. Sargeant, Ian A. Gardner, James S. Dickson, Mary E. Torrence, Cate E. Dewey, Ian R. Dohoo, Richard B. Evans, Jeffrey T. Gray, Mattias Greiner, Greg Keefe, Sandra L. Lefebvre, Paul S. Morley, Alejandro Ramirez, William Sischo, David R. Smith, Kate Snedeker, John N. Sofos, Michael P. Ward, Robert W. Wills

Veterinary Diagnostic and Production Animal Medicine Publications

The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes presents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A two-day consensus meeting was held on November 18–19, 2008 in Chicago, Ill, United States of America, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock production specialists, journal ...


Physiologic Effects Of Nasopharyngeal Administration Of Supplemental Oxygen At Various Flow Rates In Healthy Neonatal Foals, David M. Wong, Cody J. Alcott, Chong Wang, Bonnie L. Hay-Kraus, Benjamin R. Buchanan, Charles W. Brockus 2010 Iowa State University

Physiologic Effects Of Nasopharyngeal Administration Of Supplemental Oxygen At Various Flow Rates In Healthy Neonatal Foals, David M. Wong, Cody J. Alcott, Chong Wang, Bonnie L. Hay-Kraus, Benjamin R. Buchanan, Charles W. Brockus

Veterinary Diagnostic and Production Animal Medicine Publications

Objective—To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (Fio2) and other arterial blood gas variables in healthy neonatal foals.

Animals—9 healthy neonatal (3- to 4-day-old) foals.

Procedures—In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the level of the medial canthus of each eye; oxygen was administered at 4 flow rates through either 1 or both cannulae (8 treatments/foal). Intratracheal Fio2, intratracheal end-tidal partial pressure of carbon dioxide, and arterial ...


Exploring The Value Of Group And Traditional Obstetrical Appointments To Reduce Health Disparity, Helene M. Holbrook 2010 University of San Francisco

Exploring The Value Of Group And Traditional Obstetrical Appointments To Reduce Health Disparity, Helene M. Holbrook

Doctor of Nursing Practice (DNP) Projects

Disparity in health outcomes is influenced by socioeconomic factors that may include access to important healthcare information in a culturally sensitive way. Can a group appointment model like the CenteringPregnancy model provide a more effective means for engaging Spanish-speaking pregnant women? Research studies using the group prenatal appointment model show increased pregnancy knowledge, readiness for labor and higher satisfaction compared with individual prenatal appointments. This paper discusses the importance of reducing disparities in birth outcomes using a group appointment model conducted in partial fulfillment for the Doctor of Nursing Practice degree.


The Impact Of Patient-Centered Narrative Interviewing On The Perceptions Of Primary Care Clinicians: A Pilot Evaluation, Michael James Terry 2010 University of San Francisco

The Impact Of Patient-Centered Narrative Interviewing On The Perceptions Of Primary Care Clinicians: A Pilot Evaluation, Michael James Terry

Doctor of Nursing Practice (DNP) Projects

In this project, psychiatric nurses were trained in patient-centered narrative interviewing approaches and placed in a variety of healthcare sites and conditions to function as consultants. Primary care clinicians (PCCs) in those sites selected patients that each clinician felt was frustrating or difficult and arranged for the consultant to interview them. The consultants then presented patient information to the PCC, data typically difficult to obtain using a standard medical interviewing format. The consultant and PCC discussed the new information provided. The PCC than determined if the information provided was valuable, whether it changed their clinical decision-making regarding this patient's ...


Newborn Umbilical Cord Care: An Evidence Based Quality Improvement Project, Janeen Marie Whitmore 2010 University of San Francisco

Newborn Umbilical Cord Care: An Evidence Based Quality Improvement Project, Janeen Marie Whitmore

Doctor of Nursing Practice (DNP) Projects

No Abstract Available


Discrimination Of Tone Contrasts In Mandarin Disyllables By Naïve American English Listeners, Shari Salzhauer Berkowitz 2010 Graduate Center, City University of New York

Discrimination Of Tone Contrasts In Mandarin Disyllables By Naïve American English Listeners, Shari Salzhauer Berkowitz

Dissertations, Theses, and Capstone Projects

The present study examined the perception of Mandarin disyllabic tones by inexperienced American English speakers. Participants heard two naturally-produced Mandarin disyllables, and indicated if the two were the same or different. A small native Mandarin-speaking control group participated as well. All 21 possible Mandarin contrasts where the initial syllable varied but the final syllable stayed the same were tested. Acoustic analysis was performed on the stimuli under study. Mandarin subjects scored at ceiling on all contrasts. American English subjects performed poorly on contrasts where the difference in mean F0 was small, or where the difference in the offset F0 of ...


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